Motif ID: PAX8.p2

Z-value: 0.139


Transcription factors associated with PAX8.p2:

Gene SymbolEntrez IDGene Name
PAX8 7849 paired box 8

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PAX8chr2_-_1137529570.039.2e-01Click!


Activity profile for motif PAX8.p2.

activity profile for motif PAX8.p2


Sorted Z-values histogram for motif PAX8.p2

Sorted Z-values for motif PAX8.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX8.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_179380301 0.218 NM_003319
NM_133378
NM_133379
NM_133432
NM_133437
TTN




titin




chr9_+_34980715 0.078 DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr8_+_39911630 0.077 NM_194294
IDO2
indoleamine 2,3-dioxygenase 2
chrX_-_33139349 0.067 NM_004006
DMD
dystrophin
chr1_-_27825178 0.061 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr1_-_171442937 0.049 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr9_+_123088690 0.048 GSN
gelsolin
chr1_+_111573855 0.037 NM_001025199
CHI3L2
chitinase 3-like 2
chrX_-_152794592 0.029 NM_000425
NM_001143963
NM_024003
L1CAM


L1 cell adhesion molecule


chr10_+_135190855 0.025 NM_000773
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr5_-_94250357 0.021 MCTP1
multiple C2 domains, transmembrane 1
chr4_+_75449720 0.021 NM_001432
EREG
epiregulin
chr2_-_87102453 0.019 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr1_-_47179729 0.013 NM_000778
CYP4A11
CYP4A22
cytochrome P450, family 4, subfamily A, polypeptide 11
cytochrome P450, family 4, subfamily A, polypeptide 22
chr17_+_9686572 0.013 GLP2R
glucagon-like peptide 2 receptor
chr7_-_99604171 0.011 NM_024637
GAL3ST4
galactose-3-O-sulfotransferase 4
chr3_-_9266251 0.005 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr18_+_57308754 0.002 NM_031891
CDH20
cadherin 20, type 2

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
335.50 3.87e-04 GO:0018685 alkane 1-monooxygenase activity
24.23 4.65e-04 GO:0020037 heme binding
22.60 6.13e-04 GO:0046906 tetrapyrrole binding
191.74 1.35e-03 GO:0016713 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen
14.25 3.75e-03 GO:0005506 iron ion binding
27.62 4.50e-03 GO:0004497 monooxygenase activity
16.55 2.05e-02 GO:0016705 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
13.12 4.03e-02 GO:0009055 electron carrier activity