Motif ID: SPIB.p2

Z-value: 2.123


Transcription factors associated with SPIB.p2:

Gene SymbolEntrez IDGene Name
SPIB 6689 Spi-B transcription factor (Spi-1/PU.1 related)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPIBchr19_+_556140060.783.5e-04Click!


Activity profile for motif SPIB.p2.

activity profile for motif SPIB.p2


Sorted Z-values histogram for motif SPIB.p2

Sorted Z-values for motif SPIB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPIB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_15005761 8.931 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chrX_+_48427103 4.987 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr18_-_51219880 4.463 TCF4
transcription factor 4
chr16_+_30102426 3.259 CORO1A
coronin, actin binding protein, 1A
chr2_-_175207521 3.249 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr6_-_32742265 3.113 NM_002123
HLA-DQB1
major histocompatibility complex, class II, DQ beta 1
chr10_-_64246129 3.112 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr17_+_31455332 2.897 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr12_+_25096755 2.856 LRMP
lymphoid-restricted membrane protein
chr2_-_96174865 2.693 NM_004418
DUSP2
dual specificity phosphatase 2
chr17_+_31664143 2.613 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr3_-_122862447 2.577 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr22_+_21552897 2.473 LOC100290481
immunoglobulin lambda light chain-like
chr19_+_54530497 2.446 CD37
CD37 molecule
chr10_+_70517863 2.440 SRGN
serglycin
chr19_+_54530485 2.434 NM_001040031
NM_001774
CD37

CD37 molecule

chr1_-_181826086 2.431 NCF2
neutrophil cytosolic factor 2
chr6_-_32268267 2.420 GPSM3
G-protein signaling modulator 3
chr12_+_25096472 2.416 NM_006152
LRMP
lymphoid-restricted membrane protein
chr1_-_181826633 2.415 NM_001127651
NCF2
neutrophil cytosolic factor 2
chr10_+_70517823 2.411 NM_002727
SRGN
serglycin
chr19_+_54530512 2.365 CD37
CD37 molecule
chr1_-_25128951 2.352 RUNX3
runt-related transcription factor 3
chr19_+_54530546 2.337 CD37
CD37 molecule
chr3_-_122862391 2.317 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr19_+_54530458 2.268 CD37
CD37 molecule
chr1_-_181826292 2.217 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chr17_+_64922420 2.169 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr11_+_59979857 2.145 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr4_+_39874921 2.125 NM_004310
RHOH
ras homolog gene family, member H
chr14_+_87541220 2.066 NM_003608
GPR65
G protein-coupled receptor 65
chr12_+_53177806 2.037 NCKAP1L
NCK-associated protein 1-like
chr3_+_48482213 2.020 NM_016381
NM_033629
TREX1

three prime repair exonuclease 1

chr17_-_26665220 1.975 NM_006495
EVI2B
ecotropic viral integration site 2B
chr12_+_46785922 1.968 NM_001166686
PFKM
phosphofructokinase, muscle
chr12_+_4253143 1.925 NM_001759
CCND2
cyclin D2
chr17_-_26665213 1.924 EVI2B
ecotropic viral integration site 2B
chrX_+_48427137 1.909 WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr12_+_53177789 1.894 NCKAP1L
NCK-associated protein 1-like
chr7_+_68701704 1.881 NM_001127231
NM_001127232
NM_015570
AUTS2


autism susceptibility candidate 2


chr17_+_31562577 1.850 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr12_+_53177758 1.846 NM_005337
NCKAP1L
NCK-associated protein 1-like
chr22_+_21495273 1.843


chr5_-_169657312 1.786 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr17_-_26665144 1.779 EVI2B
ecotropic viral integration site 2B
chr12_+_6930778 1.774 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chrX_-_70248022 1.769 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr12_+_6930799 1.769 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr5_-_169657395 1.756 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr4_-_25473528 1.754 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr12_+_6930792 1.753 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr4_+_103641854 1.751 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr12_+_6930804 1.744 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr6_-_32268615 1.704 GPSM3
G-protein signaling modulator 3
chr5_-_169657360 1.667 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr19_-_40925151 1.665 NM_024660
TMEM149
transmembrane protein 149
chr17_-_26665194 1.664 EVI2B
ecotropic viral integration site 2B
chr11_-_58099884 1.656 NM_004811
LPXN
leupaxin
chr17_-_26672757 1.652 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr10_+_17312654 1.629 VIM
vimentin
chrX_-_111953009 1.628 NM_001113490
AMOT
angiomotin
chr11_+_101693403 1.622 NM_001165
NM_182962
BIRC3

baculoviral IAP repeat containing 3

chr1_-_205161821 1.618 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chrX_-_135690770 1.616 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr12_+_6930694 1.613 NM_002831
NM_080549
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr11_-_33847937 1.609 NM_001142316
LMO2
LIM domain only 2 (rhombotin-like 1)
chr4_+_68107039 1.600 NM_012108
STAP1
signal transducing adaptor family member 1
chr5_+_168996852 1.595 DOCK2
dedicator of cytokinesis 2
chr12_+_6930815 1.592 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr11_-_33847834 1.591 LMO2
LIM domain only 2 (rhombotin-like 1)
chrX_-_135690699 1.583 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr17_-_59437782 1.576 NM_000873
ICAM2
intercellular adhesion molecule 2
chrX_-_100527799 1.542 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr3_-_120761092 1.526 NM_005191
CD80
CD80 molecule
chr7_+_68702252 1.490 AUTS2
autism susceptibility candidate 2
chr1_-_25164061 1.471 NM_001031680
RUNX3
runt-related transcription factor 3
chr11_-_33847507 1.429 LMO2
LIM domain only 2 (rhombotin-like 1)
chr17_+_37693090 1.426 NM_003152
STAT5A
signal transducer and activator of transcription 5A
chr14_-_105762742 1.393


chr7_-_37454933 1.374 NM_014800
ELMO1
engulfment and cell motility 1
chr1_+_207995999 1.374 NM_025228
TRAF3IP3
TRAF3 interacting protein 3
chr1_+_154390939 1.361 SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr1_-_31003260 1.353 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr1_-_171441234 1.335 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr6_-_154719560 1.317 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr1_-_31003181 1.306 LAPTM5
lysosomal protein transmembrane 5
chr10_-_64246080 1.302 EGR2
early growth response 2
chr17_+_69974361 1.301 CD300A
CD300a molecule
chr6_+_31647854 1.292 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr4_+_103641762 1.287 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr1_+_100957883 1.252 NM_001078
NM_080682
VCAM1

vascular cell adhesion molecule 1

chr8_-_6407882 1.240 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chrX_+_119622012 1.232 MCTS1
malignant T cell amplified sequence 1
chr14_+_64041257 1.215 ZBTB1
zinc finger and BTB domain containing 1
chr2_+_68445821 1.207 NM_002664
PLEK
pleckstrin
chrX_+_12904207 1.204 TMSB4X
TMSL3
thymosin beta 4, X-linked
thymosin-like 3
chr8_-_29263714 1.202 NM_001394
DUSP4
dual specificity phosphatase 4
chr11_-_33848061 1.178 NM_001142315
LMO2
LIM domain only 2 (rhombotin-like 1)
chr2_-_213723298 1.175 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr5_+_118719591 1.163 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr7_+_149895390 1.151 NM_018326
GIMAP4
GTPase, IMAP family member 4
chr19_+_40337846 1.142 FXYD5
FXYD domain containing ion transport regulator 5
chr11_-_66961709 1.125 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr15_-_41572558 1.122 NM_001141979
NM_001141980
TP53BP1

tumor protein p53 binding protein 1

chr5_-_169657192 1.122 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr6_+_31690957 1.121 NM_004847
NM_001623
AIF1

allograft inflammatory factor 1

chr17_+_22982372 1.088 LGALS9
lectin, galactoside-binding, soluble, 9
chr19_-_6432765 1.085 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr1_-_25129354 1.081 NM_004350
RUNX3
runt-related transcription factor 3
chr6_-_6265896 1.081 NM_000129
F13A1
coagulation factor XIII, A1 polypeptide
chr4_+_91035025 1.064 NM_007351
MMRN1
multimerin 1
chr11_+_5602782 1.064 NM_021616
TRIM34
tripartite motif containing 34
chr17_+_22982344 1.064 LGALS9
lectin, galactoside-binding, soluble, 9
chr16_+_80370426 1.062 NM_002661
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr1_+_182040837 1.062 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr17_+_22982319 1.061 LGALS9
lectin, galactoside-binding, soluble, 9
chr3_-_16530132 1.053 NM_015150
RFTN1
raftlin, lipid raft linker 1
chr11_-_60475558 1.052 NM_016582
SLC15A3
solute carrier family 15, member 3
chr17_+_22982383 1.045 LGALS9
lectin, galactoside-binding, soluble, 9
chr15_+_79376295 1.045 NM_004513
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr1_-_23758871 1.044 NM_002167
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr3_+_69216747 1.036 NM_006407
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr19_+_40337454 1.032 NM_014164
FXYD5
FXYD domain containing ion transport regulator 5
chr6_+_116707975 1.026 NM_001080976
LOC100506515
DSE
hypothetical LOC100506515
dermatan sulfate epimerase
chr6_+_32515596 1.019 NM_019111
HLA-DRA
major histocompatibility complex, class II, DR alpha
chr17_+_73676219 1.018 NM_004710
SYNGR2
synaptogyrin 2
chrX_-_15782842 1.009 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr18_-_59137488 1.001 NM_000633
NM_000657
BCL2

B-cell CLL/lymphoma 2

chrX_+_37524190 0.992 NM_000397
CYBB
cytochrome b-245, beta polypeptide
chr11_-_33848013 0.991 LMO2
LIM domain only 2 (rhombotin-like 1)
chr17_+_18320822 0.987 NM_001040078
LGALS9B
LGALS9C
lectin, galactoside-binding, soluble, 9B
lectin, galactoside-binding, soluble, 9C
chr10_-_53129315 0.987 NM_015235
CSTF2T
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chr13_-_45654327 0.986 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr14_-_105206106 0.986


chr19_+_40337480 0.983 NM_144779
NM_001164605
FXYD5

FXYD domain containing ion transport regulator 5

chrX_-_15782826 0.979


chr17_-_35975227 0.978 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr12_-_101398288 0.967 IGF1
insulin-like growth factor 1 (somatomedin C)
chr14_-_105644300 0.966 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr22_+_21053972 0.966


chrX_-_15783015 0.960 NM_003916
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr12_+_53178834 0.960 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr17_+_22982278 0.953 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr12_-_108918440 0.951 GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
chr6_+_31651319 0.943 NM_000594
TNF
tumor necrosis factor
chr19_-_44518516 0.943 NM_004877
GMFG
glia maturation factor, gamma
chrX_-_129072333 0.939 NM_001127197
ELF4
E74-like factor 4 (ets domain transcription factor)
chr8_+_98772537 0.930 MTDH
metadherin
chr8_-_28803341 0.925 NM_001172562
INTS9
integrator complex subunit 9
chr10_+_35524060 0.920 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr22_-_35875890 0.916 NM_000878
IL2RB
interleukin 2 receptor, beta
chr11_-_10786610 0.912 EIF4G2
eukaryotic translation initiation factor 4 gamma, 2
chr10_-_27189898 0.910 ABI1
abl-interactor 1
chr3_-_16529996 0.909 RFTN1
raftlin, lipid raft linker 1
chr16_+_80370400 0.907 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr4_-_105631915 0.899 NM_025212
CXXC4
CXXC finger protein 4
chr10_+_35524835 0.896 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr3_+_48482625 0.895 TREX1
three prime repair exonuclease 1
chr6_-_6265874 0.895 F13A1
coagulation factor XIII, A1 polypeptide
chr7_+_128367961 0.895 NM_001098627
IRF5
interferon regulatory factor 5
chr1_-_158883666 0.894 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr19_-_44518465 0.892 GMFG
glia maturation factor, gamma
chr22_-_35970230 0.892 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr12_-_101398503 0.887 NM_000618
NM_001111283
NM_001111285
IGF1


insulin-like growth factor 1 (somatomedin C)


chr1_+_26517032 0.886 CD52
CD52 molecule
chr20_+_44180296 0.878 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr5_+_168996816 0.872 NM_004946
DOCK2
dedicator of cytokinesis 2
chr12_-_91063441 0.872 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr1_+_26517045 0.869 CD52
CD52 molecule
chr16_+_30102231 0.869 NM_001193333
NM_007074
CORO1A

coronin, actin binding protein, 1A

chr1_-_23758503 0.865 ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr20_+_29598848 0.865 HM13
histocompatibility (minor) 13
chr1_-_111544784 0.860 NM_024901
DENND2D
DENN/MADD domain containing 2D
chr9_+_115382990 0.854 RGS3
regulator of G-protein signaling 3
chr14_+_49157150 0.853 NM_002408
MGAT2
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr1_-_111544820 0.850 DENND2D
DENN/MADD domain containing 2D
chr22_-_35970133 0.836 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr13_-_48008118 0.834 RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr3_+_9809776 0.834 NM_001198780
ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr10_-_98021144 0.832 NM_001114094
NM_013314
BLNK

B-cell linker

chr1_+_157246305 0.831 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr16_+_30391460 0.824 NM_001114380
NM_002209
ITGAL

integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)

chr1_+_148511806 0.821 NM_024579
C1orf54
chromosome 1 open reading frame 54
chrX_+_119621771 0.812 NM_014060
MCTS1
malignant T cell amplified sequence 1
chr19_-_40928131 0.810 NM_001040425
NM_144987
U2AF1L4

U2 small nuclear RNA auxiliary factor 1-like 4

chr3_-_191322919 0.803 NM_001134418
LEPREL1
leprecan-like 1
chr17_-_38087366 0.802 NM_016602
CCR10
chemokine (C-C motif) receptor 10
chr1_-_171442937 0.800 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr14_-_105997732 0.796 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr9_+_115246831 0.789 NM_144488
RGS3
regulator of G-protein signaling 3
chr1_+_26516967 0.789 NM_001803
CD52
CD52 molecule
chrX_+_55495262 0.789 NM_014061
MAGEH1
melanoma antigen family H, 1
chr11_+_61316968 0.788 FEN1
flap structure-specific endonuclease 1
chrX_+_78087484 0.788 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr11_+_61316928 0.787 FEN1
flap structure-specific endonuclease 1
chr2_-_88946767 0.784


chr2_-_74259308 0.784 NM_018221
MOBKL1B
MOB1, Mps One Binder kinase activator-like 1B (yeast)
chr11_+_61316989 0.784 FEN1
flap structure-specific endonuclease 1
chr22_+_21543671 0.780 IGLV4-3
immunoglobulin lambda variable 4-3
chr20_+_44180355 0.777 CD40
CD40 molecule, TNF receptor superfamily member 5

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.41 1.39e-10 GO:0002376 immune system process
1.11 3.12e-06 GO:0050794 regulation of cellular process
1.24 6.24e-06 GO:0090304 nucleic acid metabolic process
1.91 6.48e-06 GO:0051251 positive regulation of lymphocyte activation
1.27 1.12e-05 GO:0016070 RNA metabolic process
1.18 1.29e-05 GO:0007165 signal transduction
1.84 1.47e-05 GO:0050867 positive regulation of cell activation
1.97 1.58e-05 GO:0050870 positive regulation of T cell activation
1.41 1.90e-05 GO:0006955 immune response
1.06 1.94e-05 GO:0009987 cellular process
1.10 2.41e-05 GO:0050789 regulation of biological process
1.20 2.98e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25 3.13e-05 GO:0010467 gene expression
1.83 3.73e-05 GO:0002696 positive regulation of leukocyte activation
1.09 3.91e-05 GO:0065007 biological regulation
1.16 7.73e-05 GO:0023052 signaling
1.14 9.03e-05 GO:0044260 cellular macromolecule metabolic process
1.82 1.25e-04 GO:0050863 regulation of T cell activation
1.15 1.54e-04 GO:0051716 cellular response to stimulus
1.71 2.89e-04 GO:0051249 regulation of lymphocyte activation
1.66 3.01e-04 GO:0050865 regulation of cell activation
1.39 3.11e-04 GO:0002682 regulation of immune system process
1.11 9.95e-04 GO:0050896 response to stimulus
1.63 1.54e-03 GO:0002694 regulation of leukocyte activation
1.46 1.90e-03 GO:0002684 positive regulation of immune system process
1.99 2.04e-03 GO:0050851 antigen receptor-mediated signaling pathway
1.22 2.51e-03 GO:0007166 cell surface receptor linked signaling pathway
1.43 2.55e-03 GO:0001775 cell activation
1.62 2.56e-03 GO:0045321 leukocyte activation
1.30 3.54e-03 GO:0032774 RNA biosynthetic process
1.68 5.27e-03 GO:0002764 immune response-regulating signaling pathway
1.69 5.40e-03 GO:0002757 immune response-activating signal transduction
1.73 8.03e-03 GO:0050900 leukocyte migration
1.66 8.79e-03 GO:0046649 lymphocyte activation
2.14 1.45e-02 GO:0031294 lymphocyte costimulation
2.14 1.45e-02 GO:0031295 T cell costimulation
1.31 1.98e-02 GO:0006952 defense response
1.21 2.27e-02 GO:0034645 cellular macromolecule biosynthetic process
1.83 3.57e-02 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.82 3.63e-02 GO:0002768 immune response-regulating cell surface receptor signaling pathway
1.78 3.71e-02 GO:0042110 T cell activation
1.20 4.75e-02 GO:0009059 macromolecule biosynthetic process
2.36 4.99e-02 GO:0006413 translational initiation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.23 5.73e-06 GO:0005829 cytosol
1.17 9.66e-06 GO:0032991 macromolecular complex
1.49 1.23e-05 GO:0030529 ribonucleoprotein complex
3.45 5.76e-03 GO:0005852 eukaryotic translation initiation factor 3 complex
1.14 7.62e-03 GO:0043234 protein complex
1.09 9.58e-03 GO:0044446 intracellular organelle part
1.17 1.05e-02 GO:0044428 nuclear part
1.09 1.17e-02 GO:0044422 organelle part
1.06 2.45e-02 GO:0005737 cytoplasm
1.02 3.52e-02 GO:0005623 cell
1.02 4.33e-02 GO:0044464 cell part
1.04 4.46e-02 GO:0044424 intracellular part
1.17 4.69e-02 GO:0031981 nuclear lumen

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.11 1.08e-07 GO:0005515 protein binding
1.39 1.26e-05 GO:0003723 RNA binding
1.04 3.33e-03 GO:0005488 binding
1.14 1.22e-02 GO:0003676 nucleic acid binding