Motif ID: PATZ1.p2

Z-value: 1.468


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PATZ1chr22_-_300723290.792.8e-04Click!


Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_37245860 4.730 NM_002648
 PIM1
pim-1 oncogene
chrX_+_138060 4.324 NM_018390
 PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chrY_+_138060 4.324 NM_018390
 PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr7_-_158073121 2.644 NM_002847
NM_130842
NM_130843
 PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr19_-_18578631 2.537 NM_004750
 CRLF1
cytokine receptor-like factor 1
chr19_-_18578577 2.518 CRLF1
cytokine receptor-like factor 1
chr11_-_116213511 2.395 NM_000039
 APOA1
apolipoprotein A-I
chr2_+_47449951 2.374 EPCAM
epithelial cell adhesion molecule
chr20_-_3102169 2.343 ProSAPiP1
ProSAPiP1 protein
chr19_-_45888259 2.330 NM_004756
 NUMBL
numb homolog (Drosophila)-like
chr7_-_103417198 2.244 NM_005045
NM_173054
 RELN

reelin

chr19_+_54708312 2.158 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr20_-_23566325 2.086 NM_000099
 CST3
cystatin C
chr16_-_51138306 2.032 NM_001080430
 TOX3
TOX high mobility group box family member 3
chr19_+_54708389 2.007 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr14_-_37134191 1.975 NM_004496
 FOXA1
forkhead box A1
chr1_-_233879617 1.965 NM_001098722
 GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr2_+_47449790 1.929 NM_002354
 EPCAM
epithelial cell adhesion molecule
chr16_+_68157611 1.911 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr11_+_46359781 1.891 NM_002391
 MDK
midkine (neurite growth-promoting factor 2)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 37 entries
enrichment   p-value GO term description
1.53 6.87e-05 GO:0016569 covalent chromatin modification
1.52 1.63e-04 GO:0016570 histone modification
1.45 9.89e-08 GO:0016568 chromatin modification
1.31 1.87e-02 GO:0018193 peptidyl-amino acid modification
1.28 9.47e-03 GO:0006325 chromatin organization
1.27 4.13e-03 GO:0051253 negative regulation of RNA metabolic process
1.27 7.48e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.26 2.19e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.26 4.40e-03 GO:0010629 negative regulation of gene expression
1.25 2.64e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.25 1.12e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24 1.29e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
1.23 9.81e-03 GO:0009890 negative regulation of biosynthetic process
1.23 1.14e-02 GO:0031327 negative regulation of cellular biosynthetic process
1.22 2.47e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.21 5.90e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.20 1.24e-02 GO:0031324 negative regulation of cellular metabolic process
1.19 1.76e-02 GO:0009892 negative regulation of metabolic process
1.14 6.51e-05 GO:0010468 regulation of gene expression
1.14 2.18e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
1.67 1.42e-04 GO:0016585 chromatin remodeling complex
1.20 1.43e-02 GO:0044451 nucleoplasm part
1.17 1.37e-07 GO:0044428 nuclear part
1.17 1.69e-04 GO:0005654 nucleoplasm
1.16 2.40e-05 GO:0031981 nuclear lumen
1.13 6.41e-04 GO:0005829 cytosol
1.11 7.50e-03 GO:0043233 organelle lumen
1.11 8.22e-03 GO:0070013 intracellular organelle lumen
1.10 1.81e-02 GO:0031974 membrane-enclosed lumen
1.09 7.47e-07 GO:0005634 nucleus
1.06 1.75e-06 GO:0043227 membrane-bounded organelle
1.06 3.50e-06 GO:0043231 intracellular membrane-bounded organelle
1.06 2.27e-05 GO:0005737 cytoplasm
1.06 7.57e-03 GO:0044422 organelle part
1.06 1.52e-02 GO:0044446 intracellular organelle part
1.05 7.90e-10 GO:0005622 intracellular
1.05 2.53e-09 GO:0044424 intracellular part
1.05 4.22e-04 GO:0043226 organelle
1.05 5.35e-04 GO:0043229 intracellular organelle

Gene overrepresentation in function category:

Showing 1 to 19 of 19 entries
enrichment   p-value GO term description
1.41 5.55e-03 GO:0010843 promoter binding
1.40 5.70e-03 GO:0000975 regulatory region DNA binding
1.40 5.70e-03 GO:0001067 regulatory region nucleic acid binding
1.40 5.70e-03 GO:0044212 transcription regulatory region DNA binding
1.35 2.08e-03 GO:0016564 transcription repressor activity
1.34 3.72e-03 GO:0008134 transcription factor binding
1.32 4.93e-02 GO:0003702 RNA polymerase II transcription factor activity
1.28 4.41e-03 GO:0019904 protein domain specific binding
1.27 5.19e-05 GO:0043565 sequence-specific DNA binding
1.26 3.71e-02 GO:0003712 transcription cofactor activity
1.26 4.65e-02 GO:0000988 protein binding transcription factor activity
1.26 4.65e-02 GO:0000989 transcription factor binding transcription factor activity
1.23 1.28e-05 GO:0030528 transcription regulator activity
1.20 1.53e-03 GO:0001071 nucleic acid binding transcription factor activity
1.20 1.53e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.20 2.24e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.19 2.09e-02 GO:0016301 kinase activity
1.07 5.72e-06 GO:0005515 protein binding
1.03 2.19e-03 GO:0005488 binding