Motif ID: HMX1.p2

Z-value: 1.142


Transcription factors associated with HMX1.p2:

Gene SymbolEntrez IDGene Name
HMX1 3166 H6 family homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot


Activity profile for motif HMX1.p2.

activity profile for motif HMX1.p2


Sorted Z-values histogram for motif HMX1.p2

Sorted Z-values for motif HMX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HMX1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_48915127 2.551 NM_002668
 PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr1_-_58815415 2.111 TACSTD2
tumor-associated calcium signal transducer 2
chr22_-_35970230 1.932 NM_002872
 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr14_-_104705753 1.879 JAG2
jagged 2
chr22_-_35970133 1.640 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr19_+_43447078 1.558 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr19_+_43446937 1.407 NM_001166103
NM_021102
 SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr1_+_166461881 1.212 SFT2D2
SFT2 domain containing 2
chr5_-_81082699 1.176 NM_012446
 SSBP2
single-stranded DNA binding protein 2
chr19_+_43447262 1.168 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr5_-_81082614 1.136 SSBP2
single-stranded DNA binding protein 2
chr1_+_166461872 1.134 NM_199344
 SFT2D2
SFT2 domain containing 2
chrX_-_78509662 1.127 NM_001171581
NM_004867
 ITM2A

integral membrane protein 2A

chr13_+_40929679 1.121 C13orf15
chromosome 13 open reading frame 15
chr13_+_40929690 1.113 C13orf15
chromosome 13 open reading frame 15
chr11_-_33847507 1.111 LMO2
LIM domain only 2 (rhombotin-like 1)
chr13_+_40929525 1.102 NM_014059
 C13orf15
chromosome 13 open reading frame 15
chr11_-_33847834 1.098 LMO2
LIM domain only 2 (rhombotin-like 1)
chr17_-_59451662 1.069 NM_001099786
NM_001099787
NM_001099788
NM_001099789
 ICAM2



intercellular adhesion molecule 2



chr3_-_112796855 1.038 NM_024508
 ZBED2
zinc finger, BED-type containing 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 16 of 16 entries
enrichment   p-value GO term description
1.76 2.32e-02 GO:0006163 purine nucleotide metabolic process
1.71 1.95e-02 GO:0051094 positive regulation of developmental process
1.71 2.70e-02 GO:0072521 purine-containing compound metabolic process
1.66 2.73e-02 GO:0006753 nucleoside phosphate metabolic process
1.66 2.73e-02 GO:0009117 nucleotide metabolic process
1.65 1.25e-02 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.58 5.21e-03 GO:2000026 regulation of multicellular organismal development
1.47 4.53e-02 GO:0050793 regulation of developmental process
1.37 9.91e-04 GO:0030154 cell differentiation
1.34 3.70e-03 GO:0048869 cellular developmental process
1.33 1.48e-02 GO:0048513 organ development
1.30 2.32e-02 GO:0048523 negative regulation of cellular process
1.29 1.89e-02 GO:0048519 negative regulation of biological process
1.25 3.74e-02 GO:0048518 positive regulation of biological process
1.21 2.25e-02 GO:0023052 signaling
1.18 3.16e-02 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.24 1.80e-04 GO:0005886 plasma membrane
1.24 1.82e-04 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.11 4.40e-02 GO:0005515 protein binding