Motif ID: MZF1.p2

Z-value: 2.177


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_63776547,
chr19_-_63776442		0.194.7e-01Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_113574925 15.360 NM_001143945
 GAS6
growth arrest-specific 6
chr5_+_17270781 9.535 BASP1
brain abundant, membrane attached signal protein 1
chr5_+_17270474 8.861 NM_006317
 BASP1
brain abundant, membrane attached signal protein 1
chr10_-_126839000 5.808 CTBP2
C-terminal binding protein 2
chr10_-_126839056 5.769 NM_001329
 CTBP2
C-terminal binding protein 2
chr2_-_161058550 4.891 NM_002897
NM_016836
 RBMS1

RNA binding motif, single stranded interacting protein 1

chr4_-_158111995 4.487 NM_016205
 PDGFC
platelet derived growth factor C
chr2_-_56004366 4.446 NM_001039348
NM_001039349
 EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr7_-_150604752 4.197 NM_001003802
 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr3_-_121652183 4.099 NM_007085
 FSTL1
follistatin-like 1
chr13_-_39075200 3.700 LHFP
lipoma HMGIC fusion partner
chr2_-_161058120 3.548 RBMS1
RNA binding motif, single stranded interacting protein 1
chr10_-_126839546 3.424 NM_001083914
 CTBP2
C-terminal binding protein 2
chrX_+_73557809 3.365 NM_006517
 SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr12_+_51777684 3.199 NM_002178
 IGFBP6
insulin-like growth factor binding protein 6
chr19_+_46416938 3.180 NM_001699
NM_021913
 AXL

AXL receptor tyrosine kinase

chr10_-_79067552 3.169 NM_001014797
NM_001161352
NM_001161353
NM_002247
 KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr5_+_82803248 3.102 NM_001126336
NM_001164097
NM_001164098
NM_004385
 VCAN



versican



chr12_+_51777715 3.079 IGFBP6
insulin-like growth factor binding protein 6
chr1_+_154318954 2.883 LMNA
lamin A/C

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 93 entries
enrichment   p-value GO term description
2.00 1.34e-02 GO:0031333 negative regulation of protein complex assembly
1.84 1.87e-02 GO:0051494 negative regulation of cytoskeleton organization
1.58 3.58e-02 GO:0010639 negative regulation of organelle organization
1.49 1.39e-03 GO:0051129 negative regulation of cellular component organization
1.48 4.65e-02 GO:0032869 cellular response to insulin stimulus
1.44 3.39e-02 GO:0071375 cellular response to peptide hormone stimulus
1.43 2.85e-02 GO:0001558 regulation of cell growth
1.43 3.43e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.41 4.41e-06 GO:0000904 cell morphogenesis involved in differentiation
1.40 2.45e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.40 4.38e-02 GO:0008361 regulation of cell size
1.39 1.66e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.38 6.65e-05 GO:0031175 neuron projection development
1.37 3.32e-07 GO:0007167 enzyme linked receptor protein signaling pathway
1.37 5.71e-04 GO:0048812 neuron projection morphogenesis
1.37 1.31e-03 GO:0007409 axonogenesis
1.37 1.68e-02 GO:0071495 cellular response to endogenous stimulus
1.37 3.83e-02 GO:0032870 cellular response to hormone stimulus
1.36 9.32e-06 GO:0032989 cellular component morphogenesis
1.35 6.48e-05 GO:0048666 neuron development

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
1.92 3.09e-02 GO:0008287 protein serine/threonine phosphatase complex
1.65 4.54e-03 GO:0005925 focal adhesion
1.61 1.02e-02 GO:0005924 cell-substrate adherens junction
1.60 8.88e-03 GO:0030055 cell-substrate junction
1.43 3.49e-03 GO:0016323 basolateral plasma membrane
1.28 3.34e-03 GO:0030054 cell junction
1.25 8.96e-03 GO:0015630 microtubule cytoskeleton
1.20 9.42e-03 GO:0044430 cytoskeletal part
1.19 5.46e-04 GO:0005856 cytoskeleton
1.13 4.36e-03 GO:0005829 cytosol
1.12 5.52e-03 GO:0043228 non-membrane-bounded organelle
1.12 5.52e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.08 2.02e-03 GO:0005634 nucleus
1.03 2.72e-02 GO:0044424 intracellular part
1.03 3.64e-02 GO:0005622 intracellular
1.02 1.30e-02 GO:0044464 cell part
1.02 1.41e-02 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
1.46 7.23e-03 GO:0000975 regulatory region DNA binding
1.46 7.23e-03 GO:0001067 regulatory region nucleic acid binding
1.46 7.23e-03 GO:0044212 transcription regulatory region DNA binding
1.46 9.49e-03 GO:0010843 promoter binding
1.29 4.43e-04 GO:0043565 sequence-specific DNA binding
1.29 3.76e-03 GO:0008092 cytoskeletal protein binding
1.20 1.66e-02 GO:0030528 transcription regulator activity
1.10 9.78e-11 GO:0005515 protein binding
1.03 2.99e-02 GO:0005488 binding