Motif ID: MZF1.p2

Z-value: 2.177


Transcription factors associated with MZF1.p2:

Gene SymbolEntrez IDGene Name
MZF1 7593 myeloid zinc finger 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MZF1chr19_-_63776547,
chr19_-_63776442
0.194.7e-01Click!


Activity profile for motif MZF1.p2.

activity profile for motif MZF1.p2


Sorted Z-values histogram for motif MZF1.p2

Sorted Z-values for motif MZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MZF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_+_113574925 15.360 NM_001143945
GAS6
growth arrest-specific 6
chr5_+_17270781 9.535 BASP1
brain abundant, membrane attached signal protein 1
chr5_+_17270474 8.861 NM_006317
BASP1
brain abundant, membrane attached signal protein 1
chr10_-_126839000 5.808 CTBP2
C-terminal binding protein 2
chr10_-_126839056 5.769 NM_001329
CTBP2
C-terminal binding protein 2
chr2_-_161058550 4.891 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr4_-_158111995 4.487 NM_016205
PDGFC
platelet derived growth factor C
chr2_-_56004366 4.446 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr7_-_150604752 4.197 NM_001003802
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr3_-_121652183 4.099 NM_007085
FSTL1
follistatin-like 1
chr13_-_39075200 3.700 LHFP
lipoma HMGIC fusion partner
chr2_-_161058120 3.548 RBMS1
RNA binding motif, single stranded interacting protein 1
chr10_-_126839546 3.424 NM_001083914
CTBP2
C-terminal binding protein 2
chrX_+_73557809 3.365 NM_006517
SLC16A2
solute carrier family 16, member 2 (monocarboxylic acid transporter 8)
chr12_+_51777684 3.199 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr19_+_46416938 3.180 NM_001699
NM_021913
AXL

AXL receptor tyrosine kinase

chr10_-_79067552 3.169 NM_001014797
NM_001161352
NM_001161353
NM_002247
KCNMA1



potassium large conductance calcium-activated channel, subfamily M, alpha member 1



chr5_+_82803248 3.102 NM_001126336
NM_001164097
NM_001164098
NM_004385
VCAN



versican



chr12_+_51777715 3.079 IGFBP6
insulin-like growth factor binding protein 6
chr1_+_154318954 2.883 LMNA
lamin A/C
chr16_-_63713382 2.872 NM_001797
CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr6_+_121798443 2.852 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr7_-_150605112 2.846 NM_003078
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr2_-_227372574 2.793 IRS1
insulin receptor substrate 1
chr11_+_86189138 2.698 NM_007173
PRSS23
protease, serine, 23
chr8_+_95722448 2.690 ESRP1
epithelial splicing regulatory protein 1
chr4_-_102487356 2.681 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr21_-_27261276 2.676 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr17_+_58058783 2.653 MRC2
mannose receptor, C type 2
chr1_+_26479167 2.582 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr11_+_69165119 2.568 CCND1
cyclin D1
chr10_-_79067296 2.468 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr5_-_127901633 2.466 NM_001999
FBN2
fibrillin 2
chr12_+_13240987 2.466 EMP1
epithelial membrane protein 1
chr6_+_116798791 2.430 NM_013352
DSE
dermatan sulfate epimerase
chr8_+_95722575 2.335 ESRP1
epithelial splicing regulatory protein 1
chr8_+_95722516 2.311 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr4_-_158111504 2.263 PDGFC
platelet derived growth factor C
chr7_-_19123765 2.226 TWIST1
twist homolog 1 (Drosophila)
chr13_+_72531098 2.222 NM_001730
KLF5
Kruppel-like factor 5 (intestinal)
chr22_-_34566276 2.216 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr6_+_17501589 2.192 NM_006366
CAP2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr2_-_237987579 2.184 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chr13_-_39075355 2.181 NM_005780
LHFP
lipoma HMGIC fusion partner
chr7_+_68702252 2.179 AUTS2
autism susceptibility candidate 2
chr11_+_69165018 2.163 NM_053056
CCND1
cyclin D1
chr12_-_105056577 2.157 NUAK1
NUAK family, SNF1-like kinase, 1
chr9_-_14304036 2.140 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr21_+_46226072 2.129 NM_001848
COL6A1
collagen, type VI, alpha 1
chr13_-_39075304 2.096 LHFP
lipoma HMGIC fusion partner
chr16_-_63713485 2.043 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr1_-_103346639 2.026 NM_001190709
NM_001854
NM_080629
NM_080630
COL11A1



collagen, type XI, alpha 1



chr1_+_67168470 2.022 NM_001077701
NM_001077704
MIER1

mesoderm induction early response 1 homolog (Xenopus laevis)

chr10_-_79067210 2.020 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr12_-_105165805 2.018 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr22_-_34566367 2.005 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr1_+_26479173 2.002 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chrX_-_100801472 1.991 NM_014782
NM_177949
ARMCX2

armadillo repeat containing, X-linked 2

chr3_-_55496370 1.971 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr16_+_31390567 1.969 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr16_-_63713466 1.961 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr7_+_115952325 1.961 CAV1
caveolin 1, caveolae protein, 22kDa
chr20_+_17498507 1.938 NM_001011546
NM_006870
DSTN

destrin (actin depolymerizing factor)

chr5_-_151046680 1.911 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr1_-_142535878 1.902 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chr22_-_28972683 1.901 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chrY_-_1291526 1.875 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chrX_-_1291526 1.875 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr3_+_156280338 1.857 NM_007287
MME
membrane metallo-endopeptidase
chr13_-_109236897 1.851 NM_003749
IRS2
insulin receptor substrate 2
chr12_-_21702036 1.844 LDHB
lactate dehydrogenase B
chr12_-_21702000 1.836 LDHB
lactate dehydrogenase B
chr1_+_181259317 1.818


chr1_-_103346482 1.814 COL11A1
collagen, type XI, alpha 1
chr19_-_56178882 1.806 NM_139277
NM_005046
KLK7

kallikrein-related peptidase 7

chr16_+_54070302 1.799 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr7_+_114349376 1.795 NM_001166345
NM_001166346
NM_199072
MDFIC


MyoD family inhibitor domain containing


chr1_-_146398501 1.791 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chr4_-_102487649 1.788 NM_000944
NM_001130691
NM_001130692
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr1_+_181258952 1.781 NM_002293
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr22_-_34566210 1.768 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr12_+_4253143 1.764 NM_001759
CCND2
cyclin D2
chr6_-_167195647 1.747 NM_001006932
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr7_-_94123308 1.714 SGCE
sarcoglycan, epsilon
chr6_-_10523424 1.706 NM_003220
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr12_+_46799279 1.699 NM_000289
PFKM
phosphofructokinase, muscle
chrX_+_135058402 1.699 NM_001159700
FHL1
four and a half LIM domains 1
chr9_+_111850698 1.691 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr15_-_81667169 1.686 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr11_+_111288686 1.678 HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr10_+_17310263 1.673 NM_003380
VIM
vimentin
chr1_-_223907283 1.646 NM_001008493
NM_018212
ENAH

enabled homolog (Drosophila)

chr11_+_35596310 1.644 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr16_-_83209140 1.640 NM_021149
COTL1
coactosin-like 1 (Dictyostelium)
chr17_+_58058479 1.638 NM_006039
MRC2
mannose receptor, C type 2
chr11_-_27700180 1.630 NM_170731
BDNF
brain-derived neurotrophic factor
chr19_-_56196611 1.629 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chr7_-_19123787 1.629 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr1_+_162795328 1.621 NM_002585
PBX1
pre-B-cell leukemia homeobox 1
chr11_-_27677755 1.613 NM_170734
BDNF
brain-derived neurotrophic factor
chr2_+_36436873 1.611 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr17_-_43977273 1.606 NM_002145
HOXB2
homeobox B2
chr14_-_52487558 1.597 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr1_+_198975227 1.581 NM_203459
CAMSAP1L1
calmodulin regulated spectrin-associated protein 1-like 1
chr18_-_20105814 1.577 OSBPL1A
oxysterol binding protein-like 1A
chr11_-_27697768 1.557 NM_001143807
BDNF
brain-derived neurotrophic factor
chr21_+_41461962 1.554 BACE2
beta-site APP-cleaving enzyme 2
chr1_+_26479208 1.551 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr17_+_7728819 1.536 NM_001005271
CHD3
chromodomain helicase DNA binding protein 3
chr4_-_1156959 1.529 NM_001128325
SPON2
spondin 2, extracellular matrix protein
chr21_+_41461924 1.494 BACE2
beta-site APP-cleaving enzyme 2
chr1_-_20685314 1.481 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr1_-_56817823 1.480 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr9_-_14303899 1.462 NFIB
nuclear factor I/B
chr10_-_79067400 1.459 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr19_+_3317536 1.456 NM_005597
NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr2_-_158440587 1.453 NM_001111067
ACVR1
activin A receptor, type I
chr3_-_55490401 1.435 WNT5A
wingless-type MMTV integration site family, member 5A
chr21_+_41461597 1.433 NM_012105
NM_138991
NM_138992
BACE2


beta-site APP-cleaving enzyme 2


chr12_+_46785922 1.430 NM_001166686
PFKM
phosphofructokinase, muscle
chr17_-_45633873 1.408 COL1A1
collagen, type I, alpha 1
chr6_-_10520592 1.404 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr1_-_85816520 1.402 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr2_+_69093641 1.401 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr11_-_118799452 1.399 NM_006288
THY1
Thy-1 cell surface antigen
chr11_-_111287657 1.396 NM_001885
CRYAB
crystallin, alpha B
chr19_-_1966628 1.387 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr4_+_89147821 1.381 NM_000297
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr1_-_146543016 1.381


chr1_-_68470585 1.366 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr19_+_46416975 1.362 AXL
AXL receptor tyrosine kinase
chr3_-_151171190 1.353 NM_002628
NM_053024
PFN2

profilin 2

chr12_-_90100679 1.347 DCN
decorin
chr19_-_242335 1.341 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr12_-_21702021 1.340 LDHB
lactate dehydrogenase B
chr6_+_83130220 1.338 TPBG
trophoblast glycoprotein
chr3_-_100103142 1.337 NM_080927
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr12_+_55201854 1.336 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr12_-_90100710 1.333 DCN
decorin
chr6_-_167195987 1.328 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr10_-_69505048 1.327 NM_015601
NM_022079
HERC4

hect domain and RLD 4

chr2_+_5750229 1.320 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr17_-_43470134 1.318 NM_016429
COPZ2
coatomer protein complex, subunit zeta 2
chr12_-_21701985 1.315 NM_001174097
LDHB
lactate dehydrogenase B
chr7_+_68701704 1.315 NM_001127231
NM_001127232
NM_015570
AUTS2


autism susceptibility candidate 2


chr2_-_237987554 1.310 COL6A3
collagen, type VI, alpha 3
chr7_-_94123362 1.306 SGCE
sarcoglycan, epsilon
chr9_+_136673464 1.303 NM_000093
COL5A1
collagen, type V, alpha 1
chr4_+_174326464 1.288 NM_017423
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr1_+_157246305 1.279 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr4_-_102486975 1.267 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr4_-_1156533 1.267 NM_012445
SPON2
spondin 2, extracellular matrix protein
chr9_-_109291866 1.266 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr5_+_49998528 1.246 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr19_+_40337480 1.245 NM_144779
NM_001164605
FXYD5

FXYD domain containing ion transport regulator 5

chr5_-_151046638 1.234 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chrX_-_37964924 1.230 NM_001170750
NM_001170751
NM_001170752
NM_006307
SRPX



sushi-repeat containing protein, X-linked



chr15_+_78483624 1.219 NM_014862
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr10_-_79067476 1.215 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr15_+_66658626 1.213 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr20_+_52525538 1.203 NM_018431
DOK5
docking protein 5
chrX_-_13866451 1.203 GPM6B
glycoprotein M6B
chr17_+_2443983 1.193 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr5_+_49998677 1.184 PARP8
poly (ADP-ribose) polymerase family, member 8
chr5_-_81082614 1.183 SSBP2
single-stranded DNA binding protein 2
chr4_+_169789327 1.181 NM_001166109
PALLD
palladin, cytoskeletal associated protein
chr11_+_116575249 1.180 NM_001001522
NM_003186
TAGLN

transgelin

chr14_-_104515738 1.178 NM_138420
AHNAK2
AHNAK nucleoprotein 2
chr2_-_216008689 1.176 FN1
fibronectin 1
chr11_-_62070867 1.173 NM_001620
NM_024060
AHNAK

AHNAK nucleoprotein

chr17_+_39990124 1.165 NM_001466
FZD2
frizzled homolog 2 (Drosophila)
chr9_+_115367122 1.163 NM_134427
RGS3
regulator of G-protein signaling 3
chr19_+_16048306 1.157 TPM4
tropomyosin 4
chr19_+_46416971 1.155 AXL
AXL receptor tyrosine kinase
chr2_+_217206450 1.147 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr19_+_16048266 1.144 TPM4
tropomyosin 4
chr19_-_242168 1.141 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr12_-_90100733 1.134 NM_001920
DCN
decorin
chrX_+_102518764 1.134 NM_014380
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr16_-_83209020 1.132 COTL1
coactosin-like 1 (Dictyostelium)
chr12_+_52618815 1.131 NM_017410
HOXC13
homeobox C13
chr7_-_525556 1.130 PDGFA
platelet-derived growth factor alpha polypeptide
chr19_+_16048315 1.128 TPM4
tropomyosin 4
chr9_+_129414287 1.125 NM_001032221
NM_003165
STXBP1

syntaxin binding protein 1

chr10_-_69504956 1.125 HERC4
hect domain and RLD 4
chr17_-_45617899 1.125 COL1A1
collagen, type I, alpha 1
chr7_+_55054416 1.123 EGFR
epidermal growth factor receptor
chr17_+_2443652 1.122 NM_000430
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr4_+_30330963 1.121 NM_001173523
NM_002589
NM_032456
NM_032457
PCDH7



protocadherin 7



chr15_-_46725087 1.111 NM_000138
FBN1
fibrillin 1
chr12_+_70952729 1.105 NM_013381
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr10_-_103568197 1.104 NM_001142434
NM_012215
MGEA5

meningioma expressed antigen 5 (hyaluronidase)

chr11_-_62070775 1.103 AHNAK
AHNAK nucleoprotein
chr19_+_3317575 1.103 NFIC
nuclear factor I/C (CCAAT-binding transcription factor)
chr12_+_47498778 1.098 NM_000725
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr2_-_110230642 1.090 MALL
mal, T-cell differentiation protein-like
chr10_+_23424383 1.089 NM_012228
MSRB2
methionine sulfoxide reductase B2
chr4_-_1156378 1.089 SPON2
spondin 2, extracellular matrix protein
chr7_+_55054152 1.083 NM_005228
NM_201282
NM_201283
NM_201284
EGFR



epidermal growth factor receptor



chr18_-_51406359 1.081 TCF4
transcription factor 4

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.10 6.73e-11 GO:0065007 biological regulation
1.25 7.71e-11 GO:0030154 cell differentiation
1.24 4.00e-10 GO:0048869 cellular developmental process
1.10 1.11e-09 GO:0050794 regulation of cellular process
1.10 1.24e-09 GO:0050789 regulation of biological process
1.20 2.76e-08 GO:0048519 negative regulation of biological process
1.18 9.86e-08 GO:0048518 positive regulation of biological process
1.33 1.67e-07 GO:0022008 neurogenesis
1.20 2.04e-07 GO:0048523 negative regulation of cellular process
1.14 2.24e-07 GO:0032502 developmental process
1.25 2.58e-07 GO:0009653 anatomical structure morphogenesis
1.18 3.23e-07 GO:0048522 positive regulation of cellular process
1.37 3.32e-07 GO:0007167 enzyme linked receptor protein signaling pathway
1.05 1.74e-06 GO:0009987 cellular process
1.32 2.01e-06 GO:0051128 regulation of cellular component organization
1.40 2.45e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.30 2.84e-06 GO:0048468 cell development
1.23 2.99e-06 GO:0007399 nervous system development
1.14 3.17e-06 GO:0031323 regulation of cellular metabolic process
1.14 3.38e-06 GO:0007275 multicellular organismal development
1.41 4.41e-06 GO:0000904 cell morphogenesis involved in differentiation
1.31 5.24e-06 GO:0048699 generation of neurons
1.14 6.10e-06 GO:0080090 regulation of primary metabolic process
1.36 9.32e-06 GO:0032989 cellular component morphogenesis
1.34 1.67e-05 GO:0030182 neuron differentiation
1.09 1.73e-05 GO:0050896 response to stimulus
1.14 2.51e-05 GO:0060255 regulation of macromolecule metabolic process
1.35 6.48e-05 GO:0048666 neuron development
1.38 6.65e-05 GO:0031175 neuron projection development
1.12 7.45e-05 GO:0023052 signaling
1.14 1.07e-04 GO:0048856 anatomical structure development
1.14 1.10e-04 GO:0048731 system development
1.34 1.26e-04 GO:0000902 cell morphogenesis
1.12 1.26e-04 GO:0019222 regulation of metabolic process
1.23 1.66e-04 GO:0031325 positive regulation of cellular metabolic process
1.39 1.66e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.11 2.83e-04 GO:0051716 cellular response to stimulus
1.32 3.14e-04 GO:0030030 cell projection organization
1.12 4.10e-04 GO:0007165 signal transduction
1.16 4.36e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.22 4.60e-04 GO:0009893 positive regulation of metabolic process
1.37 5.71e-04 GO:0048812 neuron projection morphogenesis
1.15 6.66e-04 GO:0010556 regulation of macromolecule biosynthetic process
1.09 1.16e-03 GO:0043170 macromolecule metabolic process
1.22 1.21e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.24 1.23e-03 GO:0009892 negative regulation of metabolic process
1.24 1.27e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.37 1.31e-03 GO:0007409 axonogenesis
1.25 1.33e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.25 1.33e-03 GO:0031324 negative regulation of cellular metabolic process
1.49 1.39e-03 GO:0051129 negative regulation of cellular component organization
1.34 1.44e-03 GO:0048858 cell projection morphogenesis
1.12 1.61e-03 GO:0016043 cellular component organization
1.10 1.86e-03 GO:0044260 cellular macromolecule metabolic process
1.33 2.03e-03 GO:0032990 cell part morphogenesis
1.14 2.44e-03 GO:0071842 cellular component organization at cellular level
1.14 2.51e-03 GO:0031326 regulation of cellular biosynthetic process
1.11 2.56e-03 GO:0071840 cellular component organization or biogenesis
1.14 3.21e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.22 3.43e-03 GO:0051246 regulation of protein metabolic process
1.09 3.69e-03 GO:0032501 multicellular organismal process
1.14 3.83e-03 GO:0009889 regulation of biosynthetic process
1.27 4.33e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.22 5.25e-03 GO:0032268 regulation of cellular protein metabolic process
1.07 5.77e-03 GO:0044238 primary metabolic process
1.13 6.39e-03 GO:0006950 response to stress
1.13 6.78e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.17 1.10e-02 GO:0023051 regulation of signaling
1.13 1.11e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34 1.13e-02 GO:0040008 regulation of growth
1.27 1.14e-02 GO:0009725 response to hormone stimulus
1.24 1.18e-02 GO:0031328 positive regulation of cellular biosynthetic process
1.23 1.32e-02 GO:0050793 regulation of developmental process
2.00 1.34e-02 GO:0031333 negative regulation of protein complex assembly
1.23 1.57e-02 GO:0009891 positive regulation of biosynthetic process
1.14 1.66e-02 GO:0065008 regulation of biological quality
1.37 1.68e-02 GO:0071495 cellular response to endogenous stimulus
1.84 1.87e-02 GO:0051494 negative regulation of cytoskeleton organization
1.26 1.93e-02 GO:0009719 response to endogenous stimulus
1.24 2.72e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.43 2.85e-02 GO:0001558 regulation of cell growth
1.17 3.05e-02 GO:0009966 regulation of signal transduction
1.30 3.37e-02 GO:0007010 cytoskeleton organization
1.44 3.39e-02 GO:0071375 cellular response to peptide hormone stimulus
1.43 3.43e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.13 3.49e-02 GO:0010468 regulation of gene expression
1.58 3.58e-02 GO:0010639 negative regulation of organelle organization
1.37 3.83e-02 GO:0032870 cellular response to hormone stimulus
1.15 4.00e-02 GO:0048583 regulation of response to stimulus
1.40 4.38e-02 GO:0008361 regulation of cell size
1.26 4.42e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.14 4.62e-02 GO:0051252 regulation of RNA metabolic process
1.48 4.65e-02 GO:0032869 cellular response to insulin stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.19 5.46e-04 GO:0005856 cytoskeleton
1.08 2.02e-03 GO:0005634 nucleus
1.28 3.34e-03 GO:0030054 cell junction
1.43 3.49e-03 GO:0016323 basolateral plasma membrane
1.13 4.36e-03 GO:0005829 cytosol
1.65 4.54e-03 GO:0005925 focal adhesion
1.12 5.52e-03 GO:0043228 non-membrane-bounded organelle
1.12 5.52e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.60 8.88e-03 GO:0030055 cell-substrate junction
1.25 8.96e-03 GO:0015630 microtubule cytoskeleton
1.20 9.42e-03 GO:0044430 cytoskeletal part
1.61 1.02e-02 GO:0005924 cell-substrate adherens junction
1.02 1.30e-02 GO:0044464 cell part
1.02 1.41e-02 GO:0005623 cell
1.03 2.72e-02 GO:0044424 intracellular part
1.92 3.09e-02 GO:0008287 protein serine/threonine phosphatase complex
1.03 3.64e-02 GO:0005622 intracellular

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.10 9.78e-11 GO:0005515 protein binding
1.29 4.43e-04 GO:0043565 sequence-specific DNA binding
1.29 3.76e-03 GO:0008092 cytoskeletal protein binding
1.46 7.23e-03 GO:0000975 regulatory region DNA binding
1.46 7.23e-03 GO:0001067 regulatory region nucleic acid binding
1.46 7.23e-03 GO:0044212 transcription regulatory region DNA binding
1.46 9.49e-03 GO:0010843 promoter binding
1.20 1.66e-02 GO:0030528 transcription regulator activity
1.03 2.99e-02 GO:0005488 binding