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• Activity deltas table
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Motif ID: RBPJ.p2

Z-value: 1.070

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_158948176	3.159	NM_001778	CD48	CD48 molecule
chr10_+_70517863	2.243		SRGN	serglycin
chr22_+_21027538	1.840
chrX_-_70248022	1.827	NM_000206	IL2RG	interleukin 2 receptor, gamma
chr9_-_122716670	1.822	NM_001190947	TRAF1	TNF receptor-associated factor 1
chr2_-_160469438	1.753		LY75-CD302 LY75	LY75-CD302 read-through transcript lymphocyte antigen 75
chr1_+_111215343	1.664	NM_001040033	CD53	CD53 molecule
chr11_-_110755366	1.610	NM_006235	POU2AF1	POU class 2 associating factor 1
chr9_-_122728993	1.546	NM_005658	TRAF1	TNF receptor-associated factor 1
chr6_-_27548438	1.401	NM_007149	ZNF184	zinc finger protein 184
chr14_-_22354389	1.184		SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr10_+_70517823	1.067	NM_002727	SRGN	serglycin
chr5_+_112340326	1.031	NM_152624	DCP2	DCP2 decapping enzyme homolog (S. cerevisiae)
chrX_+_24393264	1.029	NM_001142386 NM_005391	PDK3	pyruvate dehydrogenase kinase, isozyme 3
chr15_+_89061579	1.011	NM_000057	BLM	Bloom syndrome, RecQ helicase-like
chr2_-_160469512	0.961	NM_001198759 NM_001198760 NM_002349	LY75-CD302 LY75	LY75-CD302 read-through transcript lymphocyte antigen 75
chr11_-_110755112	0.941		POU2AF1	POU class 2 associating factor 1
chr19_-_55220439	0.913		VRK3	vaccinia related kinase 3
chr16_+_23597691	0.893		PLK1	polo-like kinase 1
chr19_-_55220495	0.865	NM_001025778 NM_016440	VRK3	vaccinia related kinase 3
chr16_+_23597735	0.864		PLK1	polo-like kinase 1
chr12_-_55432348	0.830	NM_000946	PRIM1	primase, DNA, polypeptide 1 (49kDa)
chr16_+_23597692	0.808	NM_005030	PLK1	polo-like kinase 1
chr16_+_23597713	0.803		PLK1	polo-like kinase 1
chr16_+_23597661	0.796		PLK1	polo-like kinase 1
chr2_-_162883062	0.779	NM_022168	IFIH1	interferon induced with helicase C domain 1
chr8_+_96215144	0.778		PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr7_-_99536966	0.760		MCM7	minichromosome maintenance complex component 7
chr7_-_99536929	0.748		MCM7	minichromosome maintenance complex component 7
chr15_-_63871492	0.726		DENND4A	DENN/MADD domain containing 4A
chr5_-_169657395	0.707	NM_005565	LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr7_-_99536852	0.696		MCM7	minichromosome maintenance complex component 7
chr15_-_63871598	0.692	NM_001144823 NM_005848	DENND4A	DENN/MADD domain containing 4A
chr12_+_6930694	0.682	NM_002831 NM_080549	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr2_-_175255717	0.671	NM_001077269	WIPF1	WAS/WASL interacting protein family, member 1
chr9_-_122728173	0.671		TRAF1	TNF receptor-associated factor 1
chr2_+_172530120	0.668		HAT1	histone acetyltransferase 1
chr22_+_38652555	0.664		GRAP2	GRB2-related adaptor protein 2
chr7_-_99537362	0.664	NM_005916	MCM7	minichromosome maintenance complex component 7
chr2_-_158008763	0.655	NM_004288	CYTIP	cytohesin 1 interacting protein
chr17_-_23950171	0.641	NM_006461	SPAG5	sperm associated antigen 5
chr5_+_85949511	0.633		COX7C	cytochrome c oxidase subunit VIIc
chr16_+_30102231	0.632	NM_001193333 NM_007074	CORO1A	coronin, actin binding protein, 1A
chr8_+_145221973	0.630		CYC1	cytochrome c-1
chr6_-_49712483	0.614	NM_000324	RHAG	Rh-associated glycoprotein
chr1_+_210275752	0.613		DTL	denticleless homolog (Drosophila)
chr17_+_18700385	0.612		PRPSAP2	phosphoribosyl pyrophosphate synthetase-associated protein 2
chr12_+_9713472	0.610	NM_001197318 NM_013269 NM_001004419 NM_001197317 NM_001197319	CLEC2D	C-type lectin domain family 2, member D
chr12_+_6930778	0.591		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr12_-_9804682	0.591	NM_001781	CD69	CD69 molecule
chr19_+_49408523	0.586	NM_182490	ZNF227	zinc finger protein 227
chr22_-_35970230	0.572	NM_002872	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr5_+_85949518	0.558	NM_001867	COX7C	cytochrome c oxidase subunit VIIc
chr19_-_6432765	0.549	NM_024898	DENND1C	DENN/MADD domain containing 1C
chr8_+_96215273	0.524		PLEKHF2	pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr10_+_94342789	0.518	NM_004523	KIF11	kinesin family member 11
chrX_+_23982981	0.508	NM_001415	EIF2S3	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr1_+_51207242	0.499		CDKN2C	cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr18_-_46068048	0.495		CXXC1	CXXC finger protein 1
chr11_+_60886407	0.493		TMEM138	transmembrane protein 138
chr11_-_58102169	0.492	NM_001143995	LPXN	leupaxin
chr17_-_23950142	0.491		SPAG5	sperm associated antigen 5
chr1_+_210275541	0.477	NM_016448	DTL	denticleless homolog (Drosophila)
chr16_+_84490267	0.477	NM_002163	IRF8	interferon regulatory factor 8
chr5_-_169657312	0.468		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr4_+_140442118	0.467	NM_057175	NAA15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chrX_+_23982992	0.466		EIF2S3	eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr5_+_137542652	0.463		KIF20A	kinesin family member 20A
chr14_-_105997732	0.454		IGHA1 IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chr5_-_94443300	0.450	NM_001002796	MCTP1	multiple C2 domains, transmembrane 1
chr18_+_10516095	0.449		NAPG	N-ethylmaleimide-sensitive factor attachment protein, gamma
chr18_+_10516022	0.444		NAPG	N-ethylmaleimide-sensitive factor attachment protein, gamma
chr5_-_39110235	0.444		RICTOR	RPTOR independent companion of MTOR, complex 2
chr19_+_49268106	0.438	NM_001037813	ZNF284	zinc finger protein 284
chr19_-_55220388	0.435		VRK3	vaccinia related kinase 3
chr20_+_9443225	0.435	NM_012261	C20orf103	chromosome 20 open reading frame 103
chr12_+_6930804	0.428		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr14_-_104332895	0.427		AKT1	v-akt murine thymoma viral oncogene homolog 1
chr7_+_120378052	0.419	NM_019071 NM_198267	ING3	inhibitor of growth family, member 3
chr8_+_145221966	0.419		CYC1	cytochrome c-1
chrX_-_30505804	0.415	NM_025159	CXorf21	chromosome X open reading frame 21
chr10_-_52053617	0.415	NM_147156	SGMS1	sphingomyelin synthase 1
chr5_-_7922113	0.411	NM_024091	FASTKD3	FAST kinase domains 3
chr5_-_169657360	0.410		LCP2	lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr12_+_132073014	0.410	NM_019591	ZNF26	zinc finger protein 26
chr19_-_17377383	0.407	NM_004335	BST2	bone marrow stromal cell antigen 2
chr8_+_145221924	0.407	NM_001916	CYC1	cytochrome c-1
chr18_+_10515861	0.406	NM_003826	NAPG	N-ethylmaleimide-sensitive factor attachment protein, gamma
chr18_-_46068022	0.406		CXXC1	CXXC finger protein 1
chr10_+_94342853	0.403		KIF11	kinesin family member 11
chr9_+_99214000	0.401	NM_014290	TDRD7	tudor domain containing 7
chr18_-_46068185	0.398		CXXC1	CXXC finger protein 1
chr5_-_176769141	0.397	NM_000505	F12	coagulation factor XII (Hageman factor)
chr1_-_25129354	0.394	NM_004350	RUNX3	runt-related transcription factor 3
chr12_+_6930792	0.389		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr1_+_111484404	0.389		CEPT1	choline/ethanolamine phosphotransferase 1
chr9_+_99214190	0.387		TDRD7	tudor domain containing 7
chr15_-_36644122	0.383	NM_001128602 NM_005739	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr11_+_7574992	0.382		PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr11_-_36488343	0.379	NM_004620 NM_145803	TRAF6	TNF receptor-associated factor 6
chrX_-_118610880	0.379	NM_001173488	NKRF	NFKB repressing factor
chr18_-_46068003	0.379		CXXC1	CXXC finger protein 1
chr14_-_99911679	0.378	NM_004184 NM_213646	WARS	tryptophanyl-tRNA synthetase
chr6_-_32920167	0.378		PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr17_+_8865547	0.376	NM_004822	NTN1	netrin 1
chr9_-_35093189	0.375		STOML2	stomatin (EPB72)-like 2
chr16_+_30102426	0.368		CORO1A	coronin, actin binding protein, 1A
chr9_+_99303639	0.366	NM_003275	TMOD1	tropomodulin 1
chr10_+_59815110	0.364	NM_003201	TFAM	transcription factor A, mitochondrial
chr22_-_37598115	0.363		CBX6	chromobox homolog 6
chr15_+_72969404	0.360	NM_002435	MPI	mannose phosphate isomerase
chr1_-_27099515	0.356		GPATCH3	G patch domain containing 3
chr8_+_18111894	0.351	NM_000662 NM_001160170 NM_001160171 NM_001160172 NM_001160173 NM_001160175 NM_001160176	NAT1	N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr18_+_10516044	0.349		NAPG	N-ethylmaleimide-sensitive factor attachment protein, gamma
chr15_-_62460622	0.348	NM_001029989 NM_014736	KIAA0101	KIAA0101
chr12_+_25096472	0.347	NM_006152	LRMP	lymphoid-restricted membrane protein
chr6_+_42639929	0.342		UBR2	ubiquitin protein ligase E3 component n-recognin 2
chr2_-_191723978	0.340		STAT4	signal transducer and activator of transcription 4
chr12_+_6930799	0.340		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr16_+_21872201	0.336		UQCRC2	ubiquinol-cytochrome c reductase core protein II
chr10_+_35456095	0.329		CREM	cAMP responsive element modulator
chr2_-_191723951	0.329		STAT4	signal transducer and activator of transcription 4
chr1_+_45578464	0.322		TOE1	target of EGR1, member 1 (nuclear)
chr19_-_1993022	0.321		MKNK2	MAP kinase interacting serine/threonine kinase 2
chr5_-_88155360	0.319	NM_001193348 NM_001193349	MEF2C	myocyte enhancer factor 2C
chr10_-_88271466	0.317		WAPAL	wings apart-like homolog (Drosophila)
chr17_+_23723113	0.316	NM_015077	SARM1	sterile alpha and TIR motif containing 1
chr17_-_26175850	0.314	NM_015986	CRLF3	cytokine receptor-like factor 3
chr10_+_124903874	0.313		BUB3	budding uninhibited by benzimidazoles 3 homolog (yeast)
chr14_-_56805309	0.313		EXOC5	exocyst complex component 5
chr9_-_35093144	0.313	NM_013442	STOML2	stomatin (EPB72)-like 2
chr3_-_47798341	0.312		SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr1_-_234834410	0.311	NM_018072	HEATR1	HEAT repeat containing 1
chr1_-_27834210	0.310	NM_005248	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr12_-_119391884	0.310		SRSF9	serine/arginine-rich splicing factor 9
chr7_-_16471817	0.309	NM_015464	SOSTDC1	sclerostin domain containing 1
chr19_+_54872304	0.308	NM_001536 NM_198318	PRMT1	protein arginine methyltransferase 1
chr4_-_84475328	0.307	NM_001166498 NM_006665	HPSE	heparanase
chrX_+_122922058	0.306	NM_001042749	STAG2	stromal antigen 2
chr12_-_47679176	0.304	NM_015086	DDN	dendrin
chr12_+_6930815	0.303		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr17_+_23723220	0.303		SARM1	sterile alpha and TIR motif containing 1
chr3_+_123036719	0.302	NM_018456	EAF2	ELL associated factor 2
chr8_+_79590890	0.301	NM_006823 NM_181839	PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr16_+_21872178	0.299		UQCRC2	ubiquinol-cytochrome c reductase core protein II
chr21_+_33560608	0.298		IL10RB	interleukin 10 receptor, beta
chr2_-_191723996	0.298		STAT4	signal transducer and activator of transcription 4
chr18_+_647461	0.297	NM_001071	TYMS	thymidylate synthetase
chr22_-_37598160	0.296		CBX6	chromobox homolog 6
chr2_-_169927258	0.294	NM_004525	LRP2	low density lipoprotein receptor-related protein 2
chr18_+_647674	0.294		TYMS	thymidylate synthetase
chr12_-_119391794	0.293		SRSF9	serine/arginine-rich splicing factor 9
chr15_+_64584686	0.291		ZWILCH	Zwilch, kinetochore associated, homolog (Drosophila)
chr12_-_119391918	0.291	NM_003769	SRSF9	serine/arginine-rich splicing factor 9
chr4_-_84475024	0.290		HPSE	heparanase
chr14_-_56805367	0.290	NM_006544	EXOC5	exocyst complex component 5
chr4_-_84475023	0.289		HPSE	heparanase
chr5_-_169749215	0.287	NM_004137	KCNMB1	potassium large conductance calcium-activated channel, subfamily M, beta member 1
chr18_+_647633	0.285		TYMS	thymidylate synthetase
chr12_+_8167494	0.285	NM_016184 NM_194447 NM_194448 NM_194450	CLEC4A	C-type lectin domain family 4, member A
chr14_+_99633570	0.285		EVL	Enah/Vasp-like
chrX_-_72351381	0.284		NAP1L2	nucleosome assembly protein 1-like 2
chr15_+_64584484	0.282	NM_017975	ZWILCH	Zwilch, kinetochore associated, homolog (Drosophila)
chr19_+_55221106	0.282		ZNF473	zinc finger protein 473
chr20_+_47328575	0.278		NCRNA00275	non-protein coding RNA 275
chr10_+_111755715	0.278	NM_019903	ADD3	adducin 3 (gamma)
chr4_+_39137038	0.277	NM_006859 NM_194451	LIAS	lipoic acid synthetase
chr9_-_129752687	0.276	NM_203305	FAM102A	family with sequence similarity 102, member A
chr4_+_174528602	0.276	NM_003864	SAP30	Sin3A-associated protein, 30kDa
chr2_-_169455167	0.276	NM_020675	SPC25	SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr1_+_179269183	0.275	NM_001194999 NM_001195000 NM_001195035 NM_001531	MR1	major histocompatibility complex, class I-related
chr16_-_83209140	0.273	NM_021149	COTL1	coactosin-like 1 (Dictyostelium)
chr1_-_35097232	0.271	NM_001164824	C1orf212	chromosome 1 open reading frame 212
chr9_-_35093048	0.270		STOML2	stomatin (EPB72)-like 2
chr3_-_168674502	0.270	NM_006217	SERPINI2	serpin peptidase inhibitor, clade I (pancpin), member 2
chr1_+_153374900	0.269	NM_001122837 NM_001122839 NM_018845	SLC50A1	solute carrier family 50 (sugar transporter), member 1
chr18_+_647666	0.267		TYMS	thymidylate synthetase
chr3_-_47798337	0.267		SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr14_-_22354851	0.265	NM_001126105 NM_003982	SLC7A7	solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr6_-_32919751	0.264	NM_148919	PSMB8	proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr11_-_32408934	0.263	NM_001198551 NM_001198552	WT1	Wilms tumor 1
chrX_+_19271931	0.260	NM_000284 NM_001173454 NM_001173455 NM_001173456	PDHA1	pyruvate dehydrogenase (lipoamide) alpha 1
chr2_-_27433130	0.258		GTF3C2	general transcription factor IIIC, polypeptide 2, beta 110kDa
chr16_+_21872155	0.258		UQCRC2	ubiquinol-cytochrome c reductase core protein II
chr19_+_44590345	0.258		ZFP36	zinc finger protein 36, C3H type, homolog (mouse)
chr2_+_237143118	0.256	NM_020311	CXCR7	chemokine (C-X-C motif) receptor 7
chr17_-_26175764	0.256		CRLF3	cytokine receptor-like factor 3
chr19_-_1992862	0.253		MKNK2	MAP kinase interacting serine/threonine kinase 2
chr16_-_83209185	0.252		COTL1	coactosin-like 1 (Dictyostelium)
chr8_+_79591074	0.252		PKIA	protein kinase (cAMP-dependent, catalytic) inhibitor alpha
chr3_-_47798308	0.247		SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr2_-_191724169	0.246	NM_003151	STAT4	signal transducer and activator of transcription 4
chr14_-_92284626	0.246	NM_001008530 NM_005606	LGMN	legumain
chr1_-_38046433	0.245		YRDC	yrdC domain containing (E. coli)
chr1_+_153374967	0.244		SLC50A1	solute carrier family 50 (sugar transporter), member 1
chr2_+_88772388	0.243		RPIA	ribose 5-phosphate isomerase A
chr21_+_16024241	0.241	NM_013396	USP25	ubiquitin specific peptidase 25
chr14_-_99911528	0.241		WARS	tryptophanyl-tRNA synthetase
chr4_-_84475036	0.241	NM_001098540	HPSE	heparanase
chrX_-_137621060	0.241		FGF13	fibroblast growth factor 13

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.25	8.05e-03	GO:0071156	regulation of cell cycle arrest
1.42	1.22e-02	GO:0006996	organelle organization
1.72	1.33e-02	GO:0051276	chromosome organization
1.73	1.72e-02	GO:0000278	mitotic cell cycle
2.20	2.36e-02	GO:0000075	cell cycle checkpoint
1.65	3.14e-02	GO:0022403	cell cycle phase

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.27	7.35e-08	GO:0005634	nucleus
1.16	2.84e-06	GO:0043231	intracellular membrane-bounded organelle
1.16	3.76e-06	GO:0043227	membrane-bounded organelle
1.10	4.82e-05	GO:0005622	intracellular
1.40	5.03e-05	GO:0044428	nuclear part
1.10	2.08e-04	GO:0044424	intracellular part
1.82	2.57e-04	GO:0005694	chromosome
1.12	4.25e-04	GO:0043229	intracellular organelle
1.40	5.77e-04	GO:0031981	nuclear lumen
1.12	6.47e-04	GO:0043226	organelle
1.34	2.19e-03	GO:0070013	intracellular organelle lumen
1.82	2.73e-03	GO:0044427	chromosomal part
1.33	3.12e-03	GO:0043233	organelle lumen
1.76	4.03e-03	GO:0005730	nucleolus
1.31	4.84e-03	GO:0031974	membrane-enclosed lumen

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.29	2.18e-03	GO:0003676	nucleic acid binding
1.33	1.26e-02	GO:0003677	DNA binding
1.07	2.01e-02	GO:0005488	binding