Motif ID: NKX2-3_NKX2-5.p2

Z-value: 1.451


Transcription factors associated with NKX2-3_NKX2-5.p2:

Gene SymbolEntrez IDGene Name
NKX2-3 159296 NK2 transcription factor related, locus 3 (Drosophila)
NKX2-5 1482 NK2 transcription factor related, locus 5 (Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX2-5chr5_-_172594691-0.421.0e-01Click!


Activity profile for motif NKX2-3_NKX2-5.p2.

activity profile for motif NKX2-3_NKX2-5.p2


Sorted Z-values histogram for motif NKX2-3_NKX2-5.p2

Sorted Z-values for motif NKX2-3_NKX2-5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX2-3_NKX2-5.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_94135384 4.648 PEG10
paternally expressed 10
chr17_-_53849888 4.346 RNF43
ring finger protein 43
chr4_+_74493174 4.238 ALB
albumin
chr3_-_79899748 3.974 NM_002941
 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr17_-_61655915 3.714 NM_000042
 APOH
apolipoprotein H (beta-2-glycoprotein I)
chrX_+_105823723 3.593 NM_024539
 RNF128
ring finger protein 128
chr10_+_7785360 3.556 ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785347 3.526 ITIH2
inter-alpha (globulin) inhibitor H2
chr4_+_74493266 3.480 ALB
albumin
chr10_-_105835609 3.467 NM_000494
 COL17A1
collagen, type XVII, alpha 1
chr10_+_7785290 3.328 ITIH2
inter-alpha (globulin) inhibitor H2
chr10_+_7785331 3.303 ITIH2
inter-alpha (globulin) inhibitor H2
chr12_-_51173238 3.272 NM_005554
 KRT6A
keratin 6A
chr4_+_74493218 3.149 ALB
albumin
chrX_+_115481774 3.148 NM_007231
 SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr3_-_152517204 3.031 NM_023915
 GPR87
G protein-coupled receptor 87
chr4_+_74520796 3.029 NM_001134
 AFP
alpha-fetoprotein
chr4_+_74493331 2.884 ALB
albumin
chr10_-_105835525 2.787 COL17A1
collagen, type XVII, alpha 1
chr4_+_74493301 2.703 ALB
albumin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.58 1.63e-02 GO:0003008 system process
1.30 4.79e-04 GO:0032501 multicellular organismal process
1.30 3.34e-02 GO:0023052 signaling

Gene overrepresentation in compartment category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.36 3.61e-02 GO:0044459 plasma membrane part

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
9.43 3.99e-02 GO:0008527 taste receptor activity