Motif ID: POU2F1..3.p2

Z-value: 3.898


Transcription factors associated with POU2F1..3.p2:

Gene SymbolEntrez IDGene Name
POU2F1 5451 POU class 2 homeobox 1
POU2F2 5452 POU class 2 homeobox 2
POU2F3 25833 POU class 2 homeobox 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU2F2chr19_-_473283990.683.9e-03Click!
POU2F1chr1_+_1654565720.601.3e-02Click!
POU2F3chr11_+_1196161120.371.6e-01Click!


Activity profile for motif POU2F1..3.p2.

activity profile for motif POU2F1..3.p2


Sorted Z-values histogram for motif POU2F1..3.p2

Sorted Z-values for motif POU2F1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU2F1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_23754822 29.614 PRKCB
protein kinase C, beta
chr16_+_23754860 27.585 PRKCB
protein kinase C, beta
chr16_+_23754772 25.112 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr14_-_106084519 16.888 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_105997732 15.559 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr22_+_21116283 13.280


chr14_-_105762742 13.187


chr22_+_21065134 11.714 LOC100290481
immunoglobulin lambda light chain-like
chr22_+_21340757 11.690


chr22_+_21370394 11.533 IGL@
immunoglobulin lambda locus
chrX_-_48661226 11.287 NM_006875
PIM2
pim-2 oncogene
chr14_-_106184988 10.674 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr10_-_98021144 10.473 NM_001114094
NM_013314
BLNK

B-cell linker

chr14_-_105845570 10.452 IGHA1
immunoglobulin heavy constant alpha 1
chr14_-_105589467 10.245 LOC100126583
IGHA1
IGHG1
IGHG2
IGHM
hypothetical LOC100126583
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant mu
chr22_+_21065207 10.126 IGLJ3
immunoglobulin lambda joining 3
chr14_-_106064887 10.111 LOC100126583
IGHV3-48
IGHA1
IGHM
hypothetical LOC100126583
immunoglobulin heavy variable 3-48
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr22_+_21407066 9.544


chr6_+_12825022 9.313 PHACTR1
phosphatase and actin regulator 1
chr22_+_21495273 8.841



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
10.43 5.20e-14 GO:0006334 nucleosome assembly
10.18 9.23e-14 GO:0031497 chromatin assembly
9.71 5.72e-14 GO:0034728 nucleosome organization
9.50 9.67e-14 GO:0065004 protein-DNA complex assembly
9.31 3.33e-14 GO:0071824 protein-DNA complex subunit organization
7.97 2.41e-11 GO:0006323 DNA packaging
7.68 3.68e-12 GO:0006333 chromatin assembly or disassembly
7.01 1.12e-10 GO:0071103 DNA conformation change
5.32 4.61e-02 GO:0042113 B cell activation
3.58 1.99e-06 GO:0034622 cellular macromolecular complex assembly
3.47 1.63e-07 GO:0006325 chromatin organization
3.20 7.98e-07 GO:0034621 cellular macromolecular complex subunit organization
2.88 4.82e-06 GO:0051276 chromosome organization
2.55 9.02e-06 GO:0006955 immune response
2.37 1.09e-03 GO:0065003 macromolecular complex assembly
2.24 7.60e-04 GO:0043933 macromolecular complex subunit organization
1.99 5.21e-04 GO:0002376 immune system process
1.72 1.97e-02 GO:0006996 organelle organization

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
15.65 3.63e-19 GO:0000786 nucleosome
9.71 4.93e-14 GO:0032993 protein-DNA complex
5.91 4.22e-14 GO:0000785 chromatin
3.28 2.53e-07 GO:0044427 chromosomal part
2.98 5.89e-07 GO:0005694 chromosome
1.46 2.12e-02 GO:0043228 non-membrane-bounded organelle
1.46 2.12e-02 GO:0043232 intracellular non-membrane-bounded organelle
1.26 3.82e-02 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
10.56 8.10e-07 GO:0003823 antigen binding
1.64 1.16e-03 GO:0003677 DNA binding
1.46 5.81e-03 GO:0003676 nucleic acid binding