Motif ID: SRF.p3

Z-value: 3.811


Transcription factors associated with SRF.p3:

Gene SymbolEntrez IDGene Name
SRF 6722 serum response factor (c-fos serum response element-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SRFchr6_+_43247168-0.273.1e-01Click!


Activity profile for motif SRF.p3.

activity profile for motif SRF.p3


Sorted Z-values histogram for motif SRF.p3

Sorted Z-values for motif SRF.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of SRF.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr20_+_34603290 30.789 NM_006097
NM_181526
 MYL9

myosin, light chain 9, regulatory

chr20_+_34603311 30.426 MYL9
myosin, light chain 9, regulatory
chr2_+_73973640 18.480 ACTG2
actin, gamma 2, smooth muscle, enteric
chr2_+_73973600 18.044 NM_001615
 ACTG2
actin, gamma 2, smooth muscle, enteric
chr15_-_32875040 17.149 NM_005159
 ACTC1
actin, alpha, cardiac muscle 1
chr11_+_116575249 13.608 NM_001001522
NM_003186
 TAGLN

transgelin

chr12_+_74160779 12.865 NM_006851
 GLIPR1
GLI pathogenesis-related 1
chr10_-_90702490 11.502 NM_001613
 ACTA2
actin, alpha 2, smooth muscle, aorta
chr3_-_124822113 10.688 NM_053031
NM_053032
 MYLK

myosin light chain kinase

chr6_+_151602787 9.954 NM_005100
 AKAP12
A kinase (PRKA) anchor protein 12
chr14_-_52487558 9.803 NM_001134999
NM_001135000
NM_006832
 FERMT2


fermitin family member 2


chr3_-_124821868 9.003 MYLK
myosin light chain kinase
chr1_-_89303478 8.606 NM_002053
 GBP1
guanylate binding protein 1, interferon-inducible, 67kDa
chr3_-_101077605 7.439 NM_014890
 FILIP1L
filamin A interacting protein 1-like
chr6_+_151603201 7.173 AKAP12
A kinase (PRKA) anchor protein 12
chr9_-_78710698 6.885 NM_015225
 PRUNE2
prune homolog 2 (Drosophila)
chr7_-_94123308 6.420 SGCE
sarcoglycan, epsilon
chr19_+_16039170 6.315 NM_001145160
 TPM4
tropomyosin 4
chr1_-_227636462 6.153 NM_001100
 ACTA1
actin, alpha 1, skeletal muscle
chr7_-_94123413 5.911 NM_001099400
NM_001099401
NM_003919
 SGCE


sarcoglycan, epsilon



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
9.04 4.27e-02 GO:0030048 actin filament-based movement
6.99 1.10e-05 GO:0006936 muscle contraction
6.86 4.18e-06 GO:0003012 muscle system process
4.69 4.86e-02 GO:0007517 muscle organ development
4.39 3.32e-03 GO:0030029 actin filament-based process
3.98 4.45e-02 GO:0061061 muscle structure development
2.19 2.27e-02 GO:0003008 system process
1.49 3.82e-02 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
25.60 4.98e-09 GO:0001725 stress fiber
24.00 8.09e-10 GO:0042641 actomyosin
23.84 1.04e-08 GO:0032432 actin filament bundle
8.54 1.02e-02 GO:0016459 myosin complex
8.37 1.14e-05 GO:0044449 contractile fiber part
8.31 3.11e-06 GO:0043292 contractile fiber
8.13 1.54e-05 GO:0030016 myofibril
7.68 3.72e-04 GO:0005925 focal adhesion
7.36 5.36e-04 GO:0005924 cell-substrate adherens junction
7.15 2.34e-03 GO:0030017 sarcomere
7.12 5.34e-12 GO:0015629 actin cytoskeleton
7.06 7.59e-04 GO:0030055 cell-substrate junction
5.82 1.28e-03 GO:0005912 adherens junction
5.23 3.29e-03 GO:0070161 anchoring junction
2.74 2.41e-07 GO:0005856 cytoskeleton
2.48 3.54e-03 GO:0044430 cytoskeletal part
1.69 2.61e-02 GO:0043228 non-membrane-bounded organelle
1.69 2.61e-02 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
4.92 3.77e-02 GO:0005516 calmodulin binding
4.81 1.55e-05 GO:0003779 actin binding
3.46 2.19e-04 GO:0008092 cytoskeletal protein binding