Motif ID: MAZ.p2

Z-value: 1.547


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
MAZchr16_+_297289320.371.6e-01Click!


Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_138060 4.086 NM_018390
 PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chrY_+_138060 4.086 NM_018390
 PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr19_-_45888259 3.099 NM_004756
 NUMBL
numb homolog (Drosophila)-like
chr9_-_131845277 2.477 NM_015033
 FNBP1
formin binding protein 1
chr9_-_131845077 2.338 FNBP1
formin binding protein 1
chr6_-_29703725 2.058 GABBR1
gamma-aminobutyric acid (GABA) B receptor, 1
chr6_-_90178375 2.032 RRAGD
Ras-related GTP binding D
chr7_-_158073121 1.937 NM_002847
NM_130842
NM_130843
 PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr14_-_88953059 1.904 NM_005197
 FOXN3
forkhead box N3
chr14_-_94855848 1.861 NM_024734
 CLMN
calmin (calponin-like, transmembrane)
chr6_+_37245860 1.797 NM_002648
 PIM1
pim-1 oncogene
chr6_-_90178544 1.666 RRAGD
Ras-related GTP binding D
chr3_-_12983959 1.639 NM_014869
 IQSEC1
IQ motif and Sec7 domain 1
chr10_+_76256305 1.582 NM_012330
 MYST4
MYST histone acetyltransferase (monocytic leukemia) 4
chr2_-_61551403 1.531 USP34
ubiquitin specific peptidase 34
chr3_-_130323033 1.524 RAB43
RAB43, member RAS oncogene family
chr16_-_11588525 1.522 LITAF
lipopolysaccharide-induced TNF factor
chr16_-_51138306 1.519 NM_001080430
 TOX3
TOX high mobility group box family member 3
chr16_-_11588257 1.514 NM_001136472
NM_001136473
 LITAF

lipopolysaccharide-induced TNF factor

chr9_-_91302707 1.506 SEMA4D
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 46 entries
enrichment   p-value GO term description
1.45 9.15e-04 GO:0016569 covalent chromatin modification
1.44 1.97e-03 GO:0016570 histone modification
1.36 4.75e-05 GO:0016568 chromatin modification
1.30 5.51e-06 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.28 1.21e-05 GO:0010558 negative regulation of macromolecule biosynthetic process
1.28 7.30e-05 GO:0010629 negative regulation of gene expression
1.27 2.03e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.26 3.33e-07 GO:0010605 negative regulation of macromolecule metabolic process
1.26 3.55e-03 GO:0051253 negative regulation of RNA metabolic process
1.26 3.60e-02 GO:0032583 regulation of gene-specific transcription
1.25 5.51e-07 GO:0009892 negative regulation of metabolic process
1.25 1.89e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.25 2.00e-04 GO:0009890 negative regulation of biosynthetic process
1.25 1.35e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25 1.77e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.24 2.17e-06 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.24 3.89e-06 GO:0031324 negative regulation of cellular metabolic process
1.19 9.19e-04 GO:0051246 regulation of protein metabolic process
1.18 3.78e-03 GO:0032268 regulation of cellular protein metabolic process
1.18 1.70e-02 GO:0048468 cell development

Gene overrepresentation in compartment category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
1.14 3.77e-03 GO:0005654 nucleoplasm
1.13 4.25e-05 GO:0005829 cytosol
1.13 5.00e-04 GO:0031981 nuclear lumen
1.11 9.76e-04 GO:0070013 intracellular organelle lumen
1.11 1.01e-03 GO:0031974 membrane-enclosed lumen
1.11 1.24e-03 GO:0043233 organelle lumen
1.11 3.50e-03 GO:0044428 nuclear part
1.10 5.83e-09 GO:0005634 nucleus
1.07 1.17e-09 GO:0043227 membrane-bounded organelle
1.07 2.45e-09 GO:0043231 intracellular membrane-bounded organelle
1.06 1.32e-08 GO:0043226 organelle
1.06 2.05e-08 GO:0043229 intracellular organelle
1.05 9.90e-12 GO:0044424 intracellular part
1.05 2.75e-11 GO:0005622 intracellular
1.05 1.20e-04 GO:0005737 cytoplasm
1.05 1.48e-02 GO:0044444 cytoplasmic part
1.02 3.74e-06 GO:0005623 cell
1.02 4.52e-06 GO:0044464 cell part

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
enrichment   p-value GO term description
1.35 1.91e-02 GO:0000975 regulatory region DNA binding
1.35 1.91e-02 GO:0001067 regulatory region nucleic acid binding
1.35 1.91e-02 GO:0044212 transcription regulatory region DNA binding
1.35 3.27e-02 GO:0010843 promoter binding
1.29 4.87e-07 GO:0043565 sequence-specific DNA binding
1.29 1.66e-02 GO:0016563 transcription activator activity
1.26 1.00e-06 GO:0019899 enzyme binding
1.25 1.33e-02 GO:0004674 protein serine/threonine kinase activity
1.25 4.04e-02 GO:0000988 protein binding transcription factor activity
1.25 4.04e-02 GO:0000989 transcription factor binding transcription factor activity
1.23 1.59e-06 GO:0001071 nucleic acid binding transcription factor activity
1.23 1.59e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.22 1.83e-05 GO:0030528 transcription regulator activity
1.20 4.98e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.19 8.32e-03 GO:0016301 kinase activity
1.16 4.13e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.08 3.73e-12 GO:0005515 protein binding
1.03 2.91e-03 GO:0005488 binding