Motif ID: TLX2.p2

Z-value: 0.949


Transcription factors associated with TLX2.p2:

Gene SymbolEntrez IDGene Name
TLX2 3196 T-cell leukemia homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
TLX2chr2_+_745950730.292.8e-01Click!


Activity profile for motif TLX2.p2.

activity profile for motif TLX2.p2


Sorted Z-values histogram for motif TLX2.p2

Sorted Z-values for motif TLX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TLX2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_46593923 1.578 NM_001040084
NM_001098845
 ANXA8L2
LOC653110
ANXA8
ANXA8L1
annexin A8-like 2
hypothetical LOC653110
annexin A8
annexin A8-like 1
chr10_+_47875229 1.508 NM_001040084
NM_001098845
 ANXA8L2
ANXA8
ANXA8L1
annexin A8-like 2
annexin A8
annexin A8-like 1
chr10_+_47216925 1.452 NM_001630
 ANXA8L2
ANXA8
annexin A8-like 2
annexin A8
chr4_+_169789327 1.321 NM_001166109
 PALLD
palladin, cytoskeletal associated protein
chr11_+_35117391 1.309 CD44
CD44 molecule (Indian blood group)
chr20_-_14266200 1.288 NM_013281
NM_198391
 FLRT3

fibronectin leucine rich transmembrane protein 3

chr6_+_116798791 1.234 NM_013352
 DSE
dermatan sulfate epimerase
chr11_+_35117408 1.214 CD44
CD44 molecule (Indian blood group)
chr1_-_151630168 1.127 NM_002964
 S100A8
S100 calcium binding protein A8
chr8_+_26491317 1.063 NM_001386
 DPYSL2
dihydropyrimidinase-like 2
chr6_-_31432954 1.044 NM_005514
 HLA-B
major histocompatibility complex, class I, B
chr1_-_68470585 0.940 NM_001002292
NM_001193334
NM_024911
 WLS


wntless homolog (Drosophila)


chr1_+_86662356 0.888 NM_006536
 CLCA2
chloride channel accessory 2
chr19_-_50601406 0.867 NM_001142502
 PPP1R13L
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr11_+_86189138 0.861 NM_007173
 PRSS23
protease, serine, 23
chr6_-_31432934 0.836 HLA-B
major histocompatibility complex, class I, B
chr1_+_151147646 0.796 NM_005547
 IVL
involucrin
chr5_+_125786975 0.796 GRAMD3
GRAM domain containing 3
chr4_+_78297356 0.793 NM_004354
 CCNG2
cyclin G2
chr3_-_78749633 0.792 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
2.25 2.73e-02 GO:0050900 leukocyte migration
1.86 2.43e-02 GO:0007411 axon guidance
1.71 9.36e-03 GO:0006935 chemotaxis
1.71 9.36e-03 GO:0042330 taxis
1.69 2.98e-02 GO:0000904 cell morphogenesis involved in differentiation
1.56 4.52e-03 GO:0040011 locomotion
1.47 1.50e-03 GO:0002376 immune system process
1.39 1.17e-03 GO:0048583 regulation of response to stimulus
1.35 3.34e-03 GO:0048869 cellular developmental process
1.35 7.94e-03 GO:0030154 cell differentiation
1.33 7.56e-05 GO:0048731 system development
1.31 8.44e-05 GO:0048856 anatomical structure development
1.27 1.46e-03 GO:0007275 multicellular organismal development
1.26 5.90e-04 GO:0032502 developmental process
1.18 3.34e-02 GO:0032501 multicellular organismal process

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
5.77 6.41e-03 GO:0042613 MHC class II protein complex
2.99 1.78e-02 GO:0015934 large ribosomal subunit
2.06 3.93e-02 GO:0070161 anchoring junction
1.41 2.56e-02 GO:0044421 extracellular region part
1.36 9.75e-04 GO:0005576 extracellular region
1.30 3.18e-03 GO:0044459 plasma membrane part
1.26 3.36e-05 GO:0071944 cell periphery
1.26 5.31e-05 GO:0005886 plasma membrane
1.17 2.00e-03 GO:0044425 membrane part
1.16 1.97e-04 GO:0016020 membrane

Nothing significant found in function category.