Motif ID: NKX6-1,2.p2

Z-value: 1.215


Transcription factors associated with NKX6-1,2.p2:

Gene SymbolEntrez IDGene Name
NKX6-1 4825 NK6 homeobox 1
NKX6-2 84504 NK6 homeobox 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX6-1chr4_-_856384100.078.0e-01Click!


Activity profile for motif NKX6-1,2.p2.

activity profile for motif NKX6-1,2.p2


Sorted Z-values histogram for motif NKX6-1,2.p2

Sorted Z-values for motif NKX6-1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX6-1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_169654742 5.202 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr2_-_151052391 3.416 NM_005168
RND3
Rho family GTPase 3
chr2_-_237987579 3.305 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chr2_-_237987554 2.666 COL6A3
collagen, type VI, alpha 3
chr12_-_90029328 2.657 LUM
lumican
chr12_-_90029672 2.603 NM_002345
LUM
lumican
chr4_+_54790020 2.549 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr4_+_40953652 2.447 NM_004181
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr13_-_37070862 2.444 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chrX_+_135058402 2.381 NM_001159700
FHL1
four and a half LIM domains 1
chr5_-_111119846 2.373 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr3_-_79899748 2.176 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr9_+_115303527 2.064 NM_130795
RGS3
regulator of G-protein signaling 3
chr20_+_19863716 2.006 RIN2
Ras and Rab interactor 2
chr7_+_93862137 1.882 COL1A2
PLAG1
collagen, type I, alpha 2
pleiomorphic adenoma gene 1
chr7_-_136679045 1.846 NM_002825
PTN
pleiotrophin
chr8_-_122722674 1.839 NM_005328
HAS2
hyaluronan synthase 2
chr6_+_114285209 1.832 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr21_+_29439768 1.823 C21orf7
chromosome 21 open reading frame 7
chrX_-_100759562 1.790 NM_001009584
NM_001184768
NM_019007
ARMCX6


armadillo repeat containing, X-linked 6



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
3.28 2.71e-02 GO:0007156 homophilic cell adhesion
3.14 1.93e-03 GO:0007517 muscle organ development

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
14.91 1.47e-02 GO:0016011 dystroglycan complex
1.64 1.86e-02 GO:0044421 extracellular region part
1.39 3.63e-02 GO:0044459 plasma membrane part
1.33 2.27e-03 GO:0071944 cell periphery
1.33 3.24e-03 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
1.94 5.25e-03 GO:0005509 calcium ion binding