Motif ID: PBX1.p2

Z-value: 0.504


Transcription factors associated with PBX1.p2:

Gene SymbolEntrez IDGene Name
PBX1 5087 pre-B-cell leukemia homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PBX1chr1_+_162795538-0.185.2e-01Click!


Activity profile for motif PBX1.p2.

activity profile for motif PBX1.p2


Sorted Z-values histogram for motif PBX1.p2

Sorted Z-values for motif PBX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PBX1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_45577144 1.314 NM_001872
NM_016413
 CPB2

carboxypeptidase B2 (plasma)

chr4_+_74496575 0.859 ALB
albumin
chr17_+_16225130 0.829


chr4_+_74499651 0.829 ALB
albumin
chr22_-_27467776 0.763 NM_001005735
NM_007194
NM_145862
 CHEK2


CHK2 checkpoint homolog (S. pombe)


chr9_-_115880366 0.755 AMBP
alpha-1-microglobulin/bikunin precursor
chr9_-_115880281 0.746 AMBP
alpha-1-microglobulin/bikunin precursor
chr9_-_115880425 0.716 AMBP
alpha-1-microglobulin/bikunin precursor
chr14_+_23654161 0.683 DCAF11
DDB1 and CUL4 associated factor 11
chr2_+_20510312 0.614 NM_004040
 RHOB
ras homolog gene family, member B
chr4_+_74496660 0.591 ALB
albumin
chr20_-_45410033 0.578 ZMYND8
zinc finger, MYND-type containing 8
chr2_-_200030944 0.531 NM_001172509
 SATB2
SATB homeobox 2
chr5_+_162797149 0.517 NM_004060
NM_199246
 CCNG1

cyclin G1

chr4_+_69716298 0.483 NM_001075
NM_001144767
 UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr15_-_35179185 0.467 MEIS2
Meis homeobox 2
chr9_-_98421894 0.440 NM_003671
NM_033331
 CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr15_-_35178888 0.440 NM_172316
 MEIS2
Meis homeobox 2
chr15_-_35180656 0.421 NM_002399
 MEIS2
Meis homeobox 2
chr1_+_15862887 0.419



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
6.73 3.31e-08 GO:0031497 chromatin assembly
6.63 3.83e-09 GO:0065004 protein-DNA complex assembly
6.53 1.90e-07 GO:0006334 nucleosome assembly
6.23 1.39e-08 GO:0071824 protein-DNA complex subunit organization
5.88 1.73e-09 GO:0006333 chromatin assembly or disassembly
5.81 1.44e-06 GO:0034728 nucleosome organization
5.54 4.08e-07 GO:0006323 DNA packaging
4.66 9.62e-06 GO:0071103 DNA conformation change
2.84 2.80e-04 GO:0034622 cellular macromolecular complex assembly
2.74 6.38e-05 GO:0006325 chromatin organization
2.70 4.23e-02 GO:0000280 nuclear division
2.70 4.23e-02 GO:0007067 mitosis
2.68 1.33e-06 GO:0051276 chromosome organization
2.31 7.13e-03 GO:0034621 cellular macromolecular complex subunit organization
1.98 2.42e-02 GO:0071844 cellular component assembly at cellular level
1.96 4.70e-02 GO:0065003 macromolecular complex assembly
1.76 4.88e-04 GO:0006996 organelle organization
1.55 6.43e-04 GO:0071842 cellular component organization at cellular level
1.51 2.10e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.42 4.73e-03 GO:0016043 cellular component organization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 21 entries
enrichment   p-value GO term description
7.62 4.55e-07 GO:0000786 nucleosome
5.40 6.68e-06 GO:0032993 protein-DNA complex
3.53 7.89e-06 GO:0000785 chromatin
2.66 1.17e-06 GO:0005694 chromosome
2.66 2.35e-05 GO:0044427 chromosomal part
1.72 1.64e-03 GO:0005654 nucleoplasm
1.57 1.77e-04 GO:0043233 organelle lumen
1.54 4.08e-04 GO:0031974 membrane-enclosed lumen
1.54 7.11e-04 GO:0070013 intracellular organelle lumen
1.54 8.26e-03 GO:0031981 nuclear lumen
1.47 2.20e-03 GO:0043228 non-membrane-bounded organelle
1.47 2.20e-03 GO:0043232 intracellular non-membrane-bounded organelle
1.34 4.63e-05 GO:0005634 nucleus
1.28 9.73e-04 GO:0044422 organelle part
1.27 3.63e-03 GO:0044446 intracellular organelle part
1.20 1.20e-04 GO:0043231 intracellular membrane-bounded organelle
1.20 1.40e-04 GO:0043227 membrane-bounded organelle
1.19 3.12e-05 GO:0043229 intracellular organelle
1.18 4.13e-05 GO:0043226 organelle
1.13 2.09e-04 GO:0044424 intracellular part

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.53 3.26e-03 GO:0003677 DNA binding
1.42 3.45e-03 GO:0003676 nucleic acid binding