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• Activity deltas table
• Regulatory interactions
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Motif ID: NFIL3.p2

Z-value: 0.947

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_+_74488910	8.807		ALB	albumin
chr4_+_74488947	8.550		ALB	albumin
chr10_-_95350949	7.670	NM_006744	RBP4	retinol binding protein 4, plasma
chr4_+_74488835	7.527	NM_000477	ALB	albumin
chr3_+_134976965	5.753		TF	transferrin
chr10_-_52315436	2.764	NM_001198818 NM_001198819 NM_001198820 NM_014576 NM_138932 NM_138933	A1CF	APOBEC1 complementation factor
chr10_-_82039158	2.207	NM_000429	MAT1A	methionine adenosyltransferase I, alpha
chr14_+_23633101	2.067	NM_001018073 NM_004563	PCK2	phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr3_+_187813538	1.989	NM_001622	AHSG	alpha-2-HS-glycoprotein
chr1_+_205328834	1.917	NM_001017365 NM_001017366	C4BPB	complement component 4 binding protein, beta
chr8_-_17797127	1.828	NM_147203 NM_201553 NM_004467 NM_201552	FGL1	fibrinogen-like 1
chrX_-_131375217	1.817	NM_001170701 NM_001170702 NM_001170703	MBNL3	muscleblind-like 3 (Drosophila)
chr17_-_38979178	1.809	NM_001079675	ETV4	ets variant 4
chr16_-_54424517	1.770	NM_001025194 NM_001025195 NM_001266	CES1	carboxylesterase 1
chr6_-_133076873	1.608	NM_004666	VNN1	vanin 1
chr17_-_38978772	1.605	NM_001986	ETV4	ets variant 4
chr7_+_45899621	1.504
chr10_-_69267774	1.500	NM_021800 NM_201262	DNAJC12	DnaJ (Hsp40) homolog, subfamily C, member 12
chr6_+_131936057	1.356	NM_000045	ARG1	arginase, liver
chr8_-_27524744	1.311	NM_203339	CLU	clusterin
chr3_+_187813553	1.263		AHSG	alpha-2-HS-glycoprotein
chr2_-_224611568	1.256	NM_001136530	SERPINE2	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr10_+_4995453	1.237	NM_001353	AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr4_+_155703581	1.157	NM_001184741 NM_005141	FGB	fibrinogen beta chain
chr2_+_101874765	1.097		MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr10_+_4995597	1.095		AKR1C1 AKR1C3	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr14_-_93919305	1.002		SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr4_-_186815116	0.993	NM_001145674 NM_001145675	SORBS2	sorbin and SH3 domain containing 2
chr16_-_54424473	0.979		CES1	carboxylesterase 1
chr3_-_101316038	0.972	NM_001042459 NM_182909	FILIP1L	filamin A interacting protein 1-like
chr1_+_210805319	0.951	NM_001030287	ATF3	activating transcription factor 3
chr10_+_4995685	0.883		AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr10_-_5035967	0.826	NM_001135241	AKR1C1 AKR1C2	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr1_+_57093030	0.816	NM_000562	C8A	complement component 8, alpha polypeptide
chr2_-_98646367	0.808	NM_001160154	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr1_+_24713396	0.798		RCAN3	RCAN family member 3
chr17_-_23965305	0.795	NM_001174103	SGK494	uncharacterized serine/threonine-protein kinase SgK494
chr4_-_70115037	0.788	NM_001073	UGT2B11	UDP glucuronosyltransferase 2 family, polypeptide B11
chr2_-_88208650	0.769	NM_001443	FABP1	fatty acid binding protein 1, liver
chr3_+_187813405	0.757		AHSG	alpha-2-HS-glycoprotein
chr2_+_101874809	0.754		MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr3_-_78749633	0.714		ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr2_+_148319033	0.637	NM_001616	ACVR2A	activin A receptor, type IIA
chrM_+_1670	0.636		USP47	ubiquitin specific peptidase 47
chr4_+_187424336	0.634		F11	coagulation factor XI
chr14_+_20226762	0.589	NM_001097577 NM_194431	ANG RNASE4	angiogenin, ribonuclease, RNase A family, 5 ribonuclease, RNase A family, 4
chr3_-_150422474	0.565	NM_000096	CP	ceruloplasmin (ferroxidase)
chr2_-_188127294	0.561		TFPI	tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr5_-_111119846	0.556	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chr5_-_32424352	0.553		ZFR	zinc finger RNA binding protein
chr16_+_70654625	0.539	NM_020995	HPR	haptoglobin-related protein
chr3_+_120984246	0.520	NM_022002	NR1I2	nuclear receptor subfamily 1, group I, member 2
chr17_-_59204622	0.505		CCDC47	coiled-coil domain containing 47
chr13_+_96672541	0.502	NM_144778 NM_207304	MBNL2	muscleblind-like 2 (Drosophila)
chr9_+_96561750	0.491	NM_001193329	C9orf3	chromosome 9 open reading frame 3
chr2_-_238861830	0.485	NM_022817	PER2	period homolog 2 (Drosophila)
chr6_-_2785682	0.473		SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr6_-_29635456	0.468		UBD	ubiquitin D
chr5_-_42847716	0.467	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr7_+_134114701	0.459	NM_004342 NM_033138 NM_033157	CALD1	caldesmon 1
chr12_-_121767272	0.456	NM_006018	GPR109B	G protein-coupled receptor 109B
chr8_-_27525084	0.456	NM_001171138	CLU	clusterin
chr17_-_59204685	0.456	NM_020198	CCDC47	coiled-coil domain containing 47
chr16_+_70646008	0.452	NM_001126102 NM_005143	HP	haptoglobin
chr17_+_38250122	0.440	NM_001158 NM_009590	AOC2	amine oxidase, copper containing 2 (retina-specific)
chr2_+_11591692	0.439	NM_014668	GREB1	growth regulation by estrogen in breast cancer 1
chr16_+_3447957	0.414	NM_001083600 NM_024845	NAT15	N-acetyltransferase 15 (GCN5-related, putative)
chr12_-_121753795	0.411	NM_177551	GPR109A	G protein-coupled receptor 109A
chr3_-_187309442	0.411	NM_004454	ETV5	ets variant 5
chr21_-_42659671	0.408	NM_003225	TFF1	trefoil factor 1
chr17_-_36346240	0.400		KRT23	keratin 23 (histone deacetylase inducible)
chr18_+_30875297	0.394	NM_014268	MAPRE2	microtubule-associated protein, RP/EB family, member 2
chr17_-_64752550	0.392	NM_080282	ABCA10	ATP-binding cassette, sub-family A (ABC1), member 10
chr4_-_69852090	0.387	NM_024743	UGT2A3	UDP glucuronosyltransferase 2 family, polypeptide A3
chr9_+_102987137	0.386	NM_017753	LPPR1	lipid phosphate phosphatase-related protein type 1
chr3_-_101077605	0.384	NM_014890	FILIP1L	filamin A interacting protein 1-like
chr3_+_23962518	0.382	NM_001145425	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr9_+_71009746	0.353	NM_001170415 NM_001170416	TJP2	tight junction protein 2 (zona occludens 2)
chr7_+_20653490	0.352	NM_001163942 NM_001163993 NM_178559	ABCB5	ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr5_-_139993469	0.349	NM_001040021 NM_001174104 NM_001174105	CD14	CD14 molecule
chr10_-_73953699	0.346	NM_001195519	CBARA1	calcium binding atopy-related autoantigen 1
chr4_+_70180805	0.339	NM_053039	UGT2B28	UDP glucuronosyltransferase 2 family, polypeptide B28
chr22_-_48607199	0.335		BRD1	bromodomain containing 1
chr19_-_51081147	0.324	NM_015649	IRF2BP1	interferon regulatory factor 2 binding protein 1
chr8_-_17599438	0.312	NM_020749	MTUS1	microtubule associated tumor suppressor 1
chr3_-_124821868	0.307		MYLK	myosin light chain kinase
chr7_+_20621769	0.307	NM_001163941	ABCB5	ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr5_+_172415891	0.306	NM_001168393 NM_001168394 NM_153607	C5orf41	chromosome 5 open reading frame 41
chr6_+_167445284	0.295	NM_004367	CCR6	chemokine (C-C motif) receptor 6
chr19_-_3936343	0.295		EEF2	eukaryotic translation elongation factor 2
chr12_-_123568781	0.289
chr1_-_180621272	0.284		GLUL	glutamate-ammonia ligase
chr19_-_17275083	0.284	NM_024527	ABHD8	abhydrolase domain containing 8
chr2_-_192420168	0.278	NM_004657	SDPR	serum deprivation response
chr10_-_116276651	0.275	NM_006720	ABLIM1	actin binding LIM protein 1
chr14_-_19867372	0.273	NM_182852 NM_182851	CCNB1IP1	cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr2_-_228290942	0.269	NM_025243	SLC19A3	solute carrier family 19, member 3
chr16_-_52094613	0.260	NM_001012398 NM_022476	AKTIP	AKT interacting protein
chr10_+_124141808	0.256	NM_021622	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr1_+_25629968	0.253	NM_018202	TMEM57	transmembrane protein 57
chr19_-_3936460	0.251	NM_001961	EEF2	eukaryotic translation elongation factor 2
chr17_-_34209671	0.247	NM_003559	PIP4K2B	phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr6_+_64289585	0.242		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr10_+_63331018	0.241	NM_032199	ARID5B	AT rich interactive domain 5B (MRF1-like)
chr9_-_72219359	0.241	NM_001206	KLF9	Kruppel-like factor 9
chr2_+_211129567	0.240	NM_001875	CPS1	carbamoyl-phosphate synthase 1, mitochondrial
chr1_+_227506751	0.231	NM_006542	SPHAR	S-phase response (cyclin related)
chr3_+_73193499	0.231	NM_018029	EBLN2	endogenous Borna-like N element-2
chr16_+_68890559	0.229	NM_001014449 NM_001014451 NM_007242	DDX19B	DEAD (Asp-Glu-Ala-As) box polypeptide 19B
chr21_-_26345294	0.227
chr4_-_186969202	0.224	NM_001145671	SORBS2	sorbin and SH3 domain containing 2
chr3_+_46591048	0.222	NM_001174136	TDGF1	teratocarcinoma-derived growth factor 1
chr17_+_77783432	0.220	NM_001042423	SLC16A3	solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr9_-_129752687	0.216	NM_203305	FAM102A	family with sequence similarity 102, member A
chr4_-_70396167	0.216	NM_021139	UGT2B4	UDP glucuronosyltransferase 2 family, polypeptide B4
chr7_-_143597313	0.208	NM_198495	CTAGE4 CTAGE8	CTAGE family, member 4 CTAGE family, member 8
chr7_+_143511480	0.206	NM_198495	CTAGE4 CTAGE8	CTAGE family, member 4 CTAGE family, member 8
chr5_-_139992621	0.205	NM_000591	CD14	CD14 molecule
chr17_-_46140015	0.199	NM_052855	ANKRD40	ankyrin repeat domain 40
chr3_+_12367993	0.197	NM_015869	PPARG	peroxisome proliferator-activated receptor gamma
chr17_+_59205289	0.192	NM_007372 NM_203499	DDX42	DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
chr9_-_78198867	0.191	NM_018339	RFK	riboflavin kinase
chr7_-_143085704	0.183	NM_178561	CTAGE6P	CTAGE family, member 6, pseudogene
chr2_-_165259334	0.182		COBLL1	COBL-like 1
chr1_+_50348052	0.180		ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr8_+_26569709	0.177		DPYSL2	dihydropyrimidinase-like 2
chr1_-_201422436	0.175		CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)
chr10_-_64698831	0.175	NM_004241	JMJD1C	jumonji domain containing 1C
chr8_+_22266256	0.172		PIWIL2	piwi-like 2 (Drosophila)
chr3_-_150858274	0.171	NM_001168280 NM_015472	WWTR1	WW domain containing transcription regulator 1
chr7_-_72574474	0.165		BAZ1B	bromodomain adjacent to zinc finger domain, 1B
chr1_+_15145001	0.163	NM_001017999	KAZN	kazrin, periplakin interacting protein
chr2_-_160362982	0.163	NM_001198763 NM_001198764 NM_014880	CD302	CD302 molecule
chr2_+_135392857	0.157	NM_001241 NM_058241	CCNT2	cyclin T2
chr8_-_103735194	0.157	NM_001032282	KLF10	Kruppel-like factor 10
chr10_+_5228756	0.155	NM_001818	AKR1C4	aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
chr12_-_69837831	0.153		TSPAN8	tetraspanin 8
chr1_+_149165438	0.153	NM_001145415 NM_012432	SETDB1	SET domain, bifurcated 1
chr14_-_21074875	0.150	NM_005407	SALL2	sal-like 2 (Drosophila)
chr9_-_111230926	0.146	NM_001145371 NM_001145372	PTPN3	protein tyrosine phosphatase, non-receptor type 3
chr1_-_201422533	0.146	NM_001276	CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)
chr11_+_9552809	0.143	NM_001143976	WEE1	WEE1 homolog (S. pombe)
chr10_-_116408046	0.142	NM_002313	ABLIM1	actin binding LIM protein 1
chr15_-_58706934	0.138	NM_002943 NM_134260	RORA	RAR-related orphan receptor A
chr8_+_69026895	0.137		PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr16_-_4528739	0.134	NM_001199055 NM_001199056 NM_013399	C16orf5	chromosome 16 open reading frame 5
chr11_-_128399218	0.133	NM_014715	ARHGAP32	Rho GTPase activating protein 32
chr11_-_62363551	0.132		WDR74	WD repeat domain 74
chr7_+_142978994	0.131	NM_001008747	CTAGE6P CTAGE15P	CTAGE family, member 6, pseudogene CTAGE family, member 15, pseudogene
chr6_+_144654565	0.130	NM_007124	UTRN	utrophin
chr16_+_2593351	0.129		LOC652276	hypothetical LOC652276
chr1_+_177261678	0.125	NM_014864	FAM20B	family with sequence similarity 20, member B
chr3_-_124822113	0.124	NM_053031 NM_053032	MYLK	myosin light chain kinase
chr2_+_201464884	0.123	NM_001142356	NIF3L1	NIF3 NGG1 interacting factor 3-like 1 (S. pombe)
chr6_+_43503263	0.122	NM_001198934	ABCC10	ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr13_-_32678142	0.122	NM_052851	STARD13	StAR-related lipid transfer (START) domain containing 13
chr8_-_110730183	0.120	NM_001099747 NM_001099748 NM_001099749 NM_001099750 NM_017786	SYBU	syntabulin (syntaxin-interacting)
chr4_-_74307637	0.117		ANKRD17	ankyrin repeat domain 17
chr17_-_36074812	0.117	NM_152349	KRT222	keratin 222
chr1_+_177261627	0.113		FAM20B	family with sequence similarity 20, member B
chr15_-_53996597	0.112	NM_198400	NEDD4	neural precursor cell expressed, developmentally down-regulated 4
chr6_+_126349268	0.111	NM_001031712	TRMT11	tRNA methyltransferase 11 homolog (S. cerevisiae)
chr4_+_3341521	0.111	NM_198227	RGS12	regulator of G-protein signaling 12
chr12_-_10870134	0.108	NM_023921	TAS2R10	taste receptor, type 2, member 10
chr12_-_10173947	0.106	NM_022570 NM_197947 NM_197948 NM_197949 NM_197950 NM_197954	CLEC7A	C-type lectin domain family 7, member A
chr21_-_26175068	0.105		APP	amyloid beta (A4) precursor protein
chrX_+_38548316	0.104		MID1IP1	MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr14_+_38805251	0.101	NM_203356	CTAGE5	CTAGE family, member 5
chr14_-_69333624	0.101	NM_003049	SLC10A1	solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr6_+_24511123	0.098	NM_020662	MRS2	MRS2 magnesium homeostasis factor homolog (S. cerevisiae)
chr7_-_143230096	0.097	NM_014719	FAM115A	family with sequence similarity 115, member A
chr2_+_190916571	0.097		INPP1	inositol polyphosphate-1-phosphatase
chr1_-_201422490	0.096		CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_+_65385799	0.095	NM_203464 NM_001005353	AK4	adenylate kinase 4
chr3_-_47932479	0.095
chrX_+_117992623	0.094	NM_001031855 NM_024778	LONRF3	LON peptidase N-terminal domain and ring finger 3
chr2_+_233961538	0.093	NM_003648	DGKD	diacylglycerol kinase, delta 130kDa
chr3_-_11598829	0.092	NM_001128220	VGLL4	vestigial like 4 (Drosophila)
chr19_+_39402167	0.091		LSM14A	LSM14A, SCD6 homolog A (S. cerevisiae)
chr14_-_35859545	0.090	NM_001144891 NM_016586	MBIP	MAP3K12 binding inhibitory protein 1
chr22_+_40559051	0.089	NM_004599	SREBF2	sterol regulatory element binding transcription factor 2
chr2_+_190916440	0.089	NM_001128928 NM_002194	INPP1	inositol polyphosphate-1-phosphatase
chr11_+_64551472	0.086	NM_013306 NM_147777	SNX15	sorting nexin 15
chr21_+_37714470	0.086	NM_130438 NM_001396	DYRK1A	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr1_-_240228987	0.085	NM_001004343	MAP1LC3C	microtubule-associated protein 1 light chain 3 gamma
chr15_-_81412354	0.085	NM_004839 NM_199330 NM_199331 NM_199332	HOMER2	homer homolog 2 (Drosophila)
chr5_+_154072654	0.083	NM_015315	LARP1	La ribonucleoprotein domain family, member 1
chrX_+_38548394	0.083		MID1IP1	MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr7_-_143213296	0.082		FAM115A	family with sequence similarity 115, member A
chrX_+_38548373	0.081		MID1IP1	MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr6_-_132073849	0.078	NM_001145659	CTAGE9	CTAGE family, member 9
chr6_-_152664906	0.076		SYNE1	spectrin repeat containing, nuclear envelope 1
chr18_-_53440012	0.076		NARS	asparaginyl-tRNA synthetase
chr15_+_91244422	0.074	NM_001042572 NM_001271	CHD2	chromodomain helicase DNA binding protein 2
chr15_+_75500284	0.074	NM_018200	HMG20A	high-mobility group 20A
chr13_-_45524846	0.074	NM_015070	ZC3H13	zinc finger CCCH-type containing 13
chr1_-_201422450	0.072		CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)
chr10_-_119795663	0.071	NM_014904	RAB11FIP2	RAB11 family interacting protein 2 (class I)
chr20_+_41569727	0.071	NM_032107	L3MBTL1	l(3)mbt-like 1 (Drosophila)
chr3_+_171167243	0.070	NM_003262	SEC62	SEC62 homolog (S. cerevisiae)

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
6.61	1.57e-02	GO:0031091	platelet alpha granule

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
53.79	3.29e-05	GO:0047023	androsterone dehydrogenase activity
53.79	1.78e-03	GO:0047115	trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity
12.23	1.22e-02	GO:0033764	steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
32.28	1.73e-02	GO:0032052	bile acid binding
10.35	2.88e-02	GO:0016229	steroid dehydrogenase activity