Motif ID: ELF1,2,4.p2

Z-value: 1.629


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
ELF1 1997 E74-like factor 1 (ets domain transcription factor)
ELF2 1998 E74-like factor 2 (ets domain transcription factor)
ELF4 2000 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ELF4chrX_-_1290721030.674.5e-03Click!
ELF2chr4_-_140317686-0.542.9e-02Click!
ELF1chr13_-_405330720.439.8e-02Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr22_-_17892859 1.892 NM_001130861
NM_003277
 CLDN5

claudin 5

chr3_+_9809776 1.774 NM_001198780
 ARPC4
actin related protein 2/3 complex, subunit 4, 20kDa
chr19_+_43447262 1.630 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chrX_+_64804259 1.479 MSN
moesin
chrX_+_64804235 1.441 NM_002444
 MSN
moesin
chrX_+_64804318 1.428 MSN
moesin
chr8_-_29262240 1.366 NM_057158
 DUSP4
dual specificity phosphatase 4
chr17_+_38238938 1.261 PSME3
proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr4_+_91035025 1.232 NM_007351
 MMRN1
multimerin 1
chr3_-_122862447 1.194 NM_005335
 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr14_+_60858151 1.190 NM_006255
 PRKCH
protein kinase C, eta
chr17_-_59817722 1.189 NM_000442
 PECAM1
platelet/endothelial cell adhesion molecule
chr8_+_22518477 1.185 NM_021174
 KIAA1967
KIAA1967
chr1_-_167603623 1.182 NM_013330
NM_197972
 NME7

non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)

chr11_-_58102169 1.166 NM_001143995
 LPXN
leupaxin
chr12_+_46785922 1.150 NM_001166686
 PFKM
phosphofructokinase, muscle
chr8_+_22518212 1.135 KIAA1967
KIAA1967
chr20_-_1321744 1.123 NM_000801
NM_054014
 FKBP1A

FK506 binding protein 1A, 12kDa

chr1_+_149298774 1.115 NM_006818
 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr3_-_122862391 1.083 HCLS1
hematopoietic cell-specific Lyn substrate 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 33 entries
enrichment   p-value GO term description
1.91 4.61e-02 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.68 1.51e-02 GO:0000082 G1/S transition of mitotic cell cycle
1.64 4.88e-04 GO:0071156 regulation of cell cycle arrest
1.63 1.62e-03 GO:0000075 cell cycle checkpoint
1.63 5.86e-03 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.63 5.86e-03 GO:0000398 nuclear mRNA splicing, via spliceosome
1.60 1.05e-02 GO:0000375 RNA splicing, via transesterification reactions
1.50 7.03e-03 GO:0008380 RNA splicing
1.42 7.75e-03 GO:0016032 viral reproduction
1.41 3.85e-02 GO:0006397 mRNA processing
1.39 3.68e-03 GO:0016071 mRNA metabolic process
1.37 3.47e-03 GO:0000278 mitotic cell cycle
1.33 1.32e-03 GO:0046907 intracellular transport
1.33 1.11e-02 GO:0022403 cell cycle phase
1.32 4.78e-02 GO:0051726 regulation of cell cycle
1.31 1.22e-02 GO:0016192 vesicle-mediated transport
1.28 3.03e-02 GO:0045184 establishment of protein localization
1.28 3.94e-02 GO:0022402 cell cycle process
1.25 5.16e-08 GO:0090304 nucleic acid metabolic process
1.25 9.16e-03 GO:0051649 establishment of localization in cell

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
enrichment   p-value GO term description
1.22 4.63e-05 GO:0031981 nuclear lumen
1.21 3.93e-06 GO:0044428 nuclear part
1.20 2.34e-05 GO:0005829 cytosol
1.19 3.03e-02 GO:0005654 nucleoplasm
1.18 1.12e-04 GO:0031974 membrane-enclosed lumen
1.18 2.64e-04 GO:0043233 organelle lumen
1.17 1.64e-03 GO:0070013 intracellular organelle lumen
1.15 4.94e-05 GO:0032991 macromolecular complex
1.15 5.73e-04 GO:0043234 protein complex
1.14 1.38e-08 GO:0005634 nucleus
1.12 1.04e-07 GO:0044444 cytoplasmic part
1.12 7.68e-06 GO:0044446 intracellular organelle part
1.11 2.16e-12 GO:0043227 membrane-bounded organelle
1.11 2.58e-12 GO:0043231 intracellular membrane-bounded organelle
1.11 2.39e-05 GO:0044422 organelle part
1.09 8.12e-11 GO:0043229 intracellular organelle
1.09 8.85e-11 GO:0043226 organelle
1.09 4.14e-08 GO:0005737 cytoplasm
1.08 1.65e-13 GO:0044424 intracellular part
1.07 8.22e-12 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.26 3.48e-02 GO:0003723 RNA binding
1.10 7.66e-07 GO:0005515 protein binding