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Motif ID: ELF1,2,4.p2

Z-value: 1.629

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr22_-_17892859	1.892	NM_001130861 NM_003277	CLDN5	claudin 5
chr3_+_9809776	1.774	NM_001198780	ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa
chr19_+_43447262	1.630		SPINT2	serine peptidase inhibitor, Kunitz type, 2
chrX_+_64804259	1.479		MSN	moesin
chrX_+_64804235	1.441	NM_002444	MSN	moesin
chrX_+_64804318	1.428		MSN	moesin
chr8_-_29262240	1.366	NM_057158	DUSP4	dual specificity phosphatase 4
chr17_+_38238938	1.261		PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr4_+_91035025	1.232	NM_007351	MMRN1	multimerin 1
chr3_-_122862447	1.194	NM_005335	HCLS1	hematopoietic cell-specific Lyn substrate 1
chr14_+_60858151	1.190	NM_006255	PRKCH	protein kinase C, eta
chr17_-_59817722	1.189	NM_000442	PECAM1	platelet/endothelial cell adhesion molecule
chr8_+_22518477	1.185	NM_021174	KIAA1967	KIAA1967
chr1_-_167603623	1.182	NM_013330 NM_197972	NME7	non-metastatic cells 7, protein expressed in (nucleoside-diphosphate kinase)
chr11_-_58102169	1.166	NM_001143995	LPXN	leupaxin
chr12_+_46785922	1.150	NM_001166686	PFKM	phosphofructokinase, muscle
chr8_+_22518212	1.135		KIAA1967	KIAA1967
chr20_-_1321744	1.123	NM_000801 NM_054014	FKBP1A	FK506 binding protein 1A, 12kDa
chr1_+_149298774	1.115	NM_006818	MLLT11	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr3_-_122862391	1.083		HCLS1	hematopoietic cell-specific Lyn substrate 1
chr8_+_22518231	1.076		KIAA1967	KIAA1967
chr17_-_59451662	1.070	NM_001099786 NM_001099787 NM_001099788 NM_001099789	ICAM2	intercellular adhesion molecule 2
chr17_-_59817575	0.996		PECAM1	platelet/endothelial cell adhesion molecule
chr19_-_53935648	0.988	NM_017805	RASIP1	Ras interacting protein 1
chr10_+_8137356	0.987		GATA3	GATA binding protein 3
chr19_+_43447078	0.980		SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr7_+_93388951	0.975	NM_004126	GNG11	guanine nucleotide binding protein (G protein), gamma 11
chr5_+_140051404	0.974		HARS2	histidyl-tRNA synthetase 2, mitochondrial (putative)
chr10_+_44816278	0.958	NM_006963	ZNF22	zinc finger protein 22 (KOX 15)
chr19_-_19615452	0.949	NM_016573	GMIP	GEM interacting protein
chr14_-_99912429	0.944	NM_173701 NM_213645	WARS	tryptophanyl-tRNA synthetase
chr14_-_99912390	0.939		WARS	tryptophanyl-tRNA synthetase
chr2_+_33514896	0.935	NM_170672	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_-_31003260	0.935	NM_006762	LAPTM5	lysosomal protein transmembrane 5
chr9_+_115303527	0.931	NM_130795	RGS3	regulator of G-protein signaling 3
chrX_+_15428820	0.913	NM_203281	BMX	BMX non-receptor tyrosine kinase
chr4_-_48477038	0.897	NM_015030	FRYL	FRY-like
chr17_-_59817456	0.890		PECAM1	platelet/endothelial cell adhesion molecule
chr10_+_129735796	0.880	NM_130435	PTPRE	protein tyrosine phosphatase, receptor type, E
chr17_-_59817654	0.869		PECAM1	platelet/endothelial cell adhesion molecule
chr1_-_31003181	0.868		LAPTM5	lysosomal protein transmembrane 5
chr12_-_21545751	0.863	NM_002907 NM_032941	RECQL	RecQ protein-like (DNA helicase Q1-like)
chr20_-_1321571	0.855		FKBP1A	FK506 binding protein 1A, 12kDa
chr8_+_22518218	0.851		KIAA1967	KIAA1967
chr19_+_43446937	0.845	NM_001166103 NM_021102	SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr5_+_162865128	0.819	NM_013283	MAT2B	methionine adenosyltransferase II, beta
chr10_+_70745615	0.804	NM_033496	HK1	hexokinase 1
chr14_-_22458134	0.797		RBM23	RNA binding motif protein 23
chr17_+_38238960	0.788		PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr2_-_175255717	0.787	NM_001077269	WIPF1	WAS/WASL interacting protein family, member 1
chr8_-_78074851	0.779	NM_000318 NM_001079867	PEX2	peroxisomal biogenesis factor 2
chr12_+_95112131	0.776	NM_005230	ELK3	ELK3, ETS-domain protein (SRF accessory protein 2)
chr14_-_66948612	0.773		PLEK2	pleckstrin 2
chr15_-_40052041	0.772	NM_139265	EHD4	EH-domain containing 4
chr15_-_40051979	0.762		EHD4	EH-domain containing 4
chr2_-_189752575	0.750	NM_000393	COL5A2	collagen, type V, alpha 2
chrX_-_10761729	0.746	NM_033290	MID1	midline 1 (Opitz/BBB syndrome)
chr10_+_1092741	0.743	NM_014023	WDR37	WD repeat domain 37
chr2_+_237143118	0.742	NM_020311	CXCR7	chemokine (C-X-C motif) receptor 7
chr6_+_30402203	0.740
chr18_+_3252110	0.734	NM_033546	MYL12B	myosin, light chain 12B, regulatory
chr9_+_126671321	0.734		ARPC5L	actin related protein 2/3 complex, subunit 5-like
chr14_-_99912340	0.727		WARS	tryptophanyl-tRNA synthetase
chr8_-_6407882	0.718	NM_001118887 NM_001118888 NM_001147	ANGPT2	angiopoietin 2
chr11_+_128068982	0.715	NM_002017	FLI1	Friend leukemia virus integration 1
chr9_+_115396020	0.712	NM_144489	RGS3	regulator of G-protein signaling 3
chr13_-_30089509	0.711		HMGB1	high-mobility group box 1
chr14_-_22458199	0.709		RBM23	RNA binding motif protein 23
chr10_-_1092643	0.705		IDI1	isopentenyl-diphosphate delta isomerase 1
chr11_-_65412409	0.704	NM_004214 NM_198897	FIBP	fibroblast growth factor (acidic) intracellular binding protein
chr11_-_407324	0.703	NM_001135053 NM_021805	SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr17_+_29606408	0.700	NM_002982	CCL2	chemokine (C-C motif) ligand 2
chr14_-_66948523	0.699	NM_016445	PLEK2	pleckstrin 2
chr12_-_6103945	0.696	NM_000552	VWF	von Willebrand factor
chr5_+_945950	0.692	NM_001166260 NM_004237	TRIP13	thyroid hormone receptor interactor 13
chr15_-_90999606	0.691	NM_207446	FAM174B	family with sequence similarity 174, member B
chr3_+_9809178	0.690	NM_001024959 NM_001024960	ARPC4	actin related protein 2/3 complex, subunit 4, 20kDa
chr18_-_50004770	0.690		MBD2	methyl-CpG binding domain protein 2
chr11_+_20342262	0.689	NM_001098523	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr10_+_12278213	0.686		CDC123	cell division cycle 123 homolog (S. cerevisiae)
chr12_-_21545473	0.685		RECQL	RecQ protein-like (DNA helicase Q1-like)
chr7_-_105539886	0.680		SYPL1	synaptophysin-like 1
chrX_+_119622012	0.675		MCTS1	malignant T cell amplified sequence 1
chr3_-_69145434	0.673	NM_173654	C3orf64	chromosome 3 open reading frame 64
chr18_-_51219880	0.669		TCF4	transcription factor 4
chr20_+_29598848	0.665		HM13	histocompatibility (minor) 13
chr11_+_128069183	0.664		FLI1	Friend leukemia virus integration 1
chr18_+_3252184	0.662		MYL12B	myosin, light chain 12B, regulatory
chr17_+_38238970	0.661		PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr1_+_84382529	0.653	NM_182948	PRKACB	protein kinase, cAMP-dependent, catalytic, beta
chr1_+_151596953	0.652	NM_002965	S100A9	S100 calcium binding protein A9
chr8_+_82355322	0.651	NM_001444	FABP5	fatty acid binding protein 5 (psoriasis-associated)
chr5_+_153398737	0.650		MFAP3	microfibrillar-associated protein 3
chr1_-_181871447	0.648		ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chr7_+_142788579	0.646		ZYX	zyxin
chr5_-_151046680	0.645	NM_003118	SPARC	secreted protein, acidic, cysteine-rich (osteonectin)
chr4_-_90978469	0.644	NM_001146055	SNCA	synuclein, alpha (non A4 component of amyloid precursor)
chrX_-_15782826	0.641
chr17_-_44042924	0.634		HOXB7	homeobox B7
chr3_-_113763049	0.631	NM_022488	ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)
chr10_+_12278200	0.631		CDC123	cell division cycle 123 homolog (S. cerevisiae)
chr5_-_102483680	0.629	NM_017676	GIN1	gypsy retrotransposon integrase 1
chr1_-_168030654	0.626	NM_033418	METTL18	methyltransferase like 18
chr5_-_171547700	0.625		STK10	serine/threonine kinase 10
chr9_-_131626184	0.621		TOR1A	torsin family 1, member A (torsin A)
chr4_-_9727394	0.619		WDR1	WD repeat domain 1
chr11_+_128069203	0.616		FLI1	Friend leukemia virus integration 1
chr4_-_9727384	0.615
chr5_+_34692239	0.613		RAI14	retinoic acid induced 14
chr1_-_224993498	0.611	NM_002221	ITPKB	inositol 1,4,5-trisphosphate 3-kinase B
chr7_+_142788566	0.610		ZYX	zyxin
chr3_-_113763454	0.610		ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)
chr3_-_49424506	0.609		RHOA	ras homolog gene family, member A
chr17_+_1892026	0.605	NM_080822	OVCA2	ovarian tumor suppressor candidate 2
chr7_+_44207131	0.604		YKT6	YKT6 v-SNARE homolog (S. cerevisiae)
chr1_-_181871508	0.602	NM_005717	ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chr6_-_112682573	0.602		LAMA4	laminin, alpha 4
chr1_-_181871462	0.601		ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chr3_-_49370755	0.600	NM_000581 NM_201397	GPX1	glutathione peroxidase 1
chr3_-_49424529	0.600	NM_001664	RHOA	ras homolog gene family, member A
chr7_+_142788517	0.600		ZYX	zyxin
chr1_-_181871473	0.599		ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chr22_-_49368066	0.598		CHKB	choline kinase beta
chr14_-_22458220	0.597	NM_001077351 NM_001077352 NM_018107	RBM23	RNA binding motif protein 23
chr3_+_48482213	0.594	NM_016381 NM_033629	TREX1	three prime repair exonuclease 1
chr1_-_114103276	0.594	NM_006608	PHTF1	putative homeodomain transcription factor 1
chr7_+_44207080	0.593		YKT6	YKT6 v-SNARE homolog (S. cerevisiae)
chr4_-_103485600	0.593	NM_001135146	SLC39A8	solute carrier family 39 (zinc transporter), member 8
chrX_-_134013644	0.591	NM_001078172 NM_001134321	FAM127B	family with sequence similarity 127, member B
chr9_+_99435900	0.591		NCBP1	nuclear cap binding protein subunit 1, 80kDa
chr4_-_177950658	0.587	NM_005429	VEGFC	vascular endothelial growth factor C
chr6_-_47030492	0.586	NM_015234	GPR116	G protein-coupled receptor 116
chr1_-_181871490	0.584		ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chrX_+_114734074	0.584	NM_001136025 NM_001172335	PLS3	plastin 3
chr10_+_12278185	0.584		CDC123	cell division cycle 123 homolog (S. cerevisiae)
chr1_-_181871416	0.582		ARPC5	actin related protein 2/3 complex, subunit 5, 16kDa
chr1_+_182040837	0.571		RGL1	ral guanine nucleotide dissociation stimulator-like 1
chr7_+_142788569	0.570		ZYX	zyxin
chr7_-_105539954	0.565	NM_182715	SYPL1	synaptophysin-like 1
chr6_-_44341222	0.563		NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr11_-_71501385	0.562	NM_014042	C11orf51	chromosome 11 open reading frame 51
chr5_+_110102639	0.562	NM_138773	SLC25A46	solute carrier family 25, member 46
chr6_-_44341296	0.562	NM_004556	NFKBIE	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr10_-_111673235	0.559	NM_001167604 NM_020383	XPNPEP1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr3_-_113763217	0.558		ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)
chr19_-_19615369	0.556		GMIP	GEM interacting protein
chr3_-_49424404	0.555		RHOA	ras homolog gene family, member A
chr1_+_26358097	0.552	NM_024869	GRRP1	glycine/arginine rich protein 1
chrX_-_15782842	0.552		AP1S2	adaptor-related protein complex 1, sigma 2 subunit
chr5_-_151046638	0.549		SPARC	secreted protein, acidic, cysteine-rich (osteonectin)
chr17_-_44043361	0.548	NM_004502	HOXB7	homeobox B7
chr10_+_17311307	0.546		VIM	vimentin
chr10_+_17311242	0.545		VIM	vimentin
chr3_-_113763425	0.544		ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)
chr11_-_404975	0.543	NM_001135054	SIGIRR	single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chrX_+_102518764	0.541	NM_014380	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr10_+_17311347	0.541		VIM	vimentin
chr3_-_49370682	0.541		GPX1	glutathione peroxidase 1
chr3_-_49424427	0.540		RHOA	ras homolog gene family, member A
chr7_+_142788521	0.540		ZYX	zyxin
chr4_+_103641511	0.537	NM_001165412 NM_003998	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr4_+_146623405	0.536	NM_001003688	SMAD1	SMAD family member 1
chr5_+_34692124	0.535	NM_001145522 NM_015577	RAI14	retinoic acid induced 14
chr5_+_34692352	0.534	NM_001145520	RAI14	retinoic acid induced 14
chr1_-_43410556	0.534	NM_006824 NM_001159936	EBNA1BP2	EBNA1 binding protein 2
chr14_+_75058518	0.532	NM_006399	BATF	basic leucine zipper transcription factor, ATF-like
chr11_+_85690900	0.531	NM_016401	C11orf73	chromosome 11 open reading frame 73
chr10_+_17311282	0.530		VIM	vimentin
chr9_-_131626237	0.530		TOR1A	torsin family 1, member A (torsin A)
chr3_-_49424397	0.529		RHOA	ras homolog gene family, member A
chr11_+_61316928	0.529		FEN1	flap structure-specific endonuclease 1
chr4_+_103641854	0.525		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr14_+_75058591	0.525		BATF	basic leucine zipper transcription factor, ATF-like
chr10_-_114196630	0.525	NM_022494	ZDHHC6	zinc finger, DHHC-type containing 6
chr3_-_49424361	0.524		RHOA	ras homolog gene family, member A
chr22_-_49368121	0.523		CHKB	choline kinase beta
chr1_+_109892760	0.519		GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr5_+_17270474	0.518	NM_006317	BASP1	brain abundant, membrane attached signal protein 1
chr10_+_17311283	0.517		VIM	vimentin
chr2_-_230494862	0.516	NM_004238	TRIP12	thyroid hormone receptor interactor 12
chr17_+_38238951	0.515		PSME3	proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
chr1_-_111548440	0.514		DENND2D	DENN/MADD domain containing 2D
chr3_-_172660545	0.514	NM_001161560 NM_001161561 NM_001161562 NM_001161563 NM_001161564 NM_001161565 NM_001161566 NM_015028	TNIK	TRAF2 and NCK interacting kinase
chr6_-_112682459	0.514	NM_001105206 NM_001105207 NM_001105208 NM_001105209 NM_002290	LAMA4	laminin, alpha 4
chr11_+_61316725	0.513	NM_004111	FEN1	flap structure-specific endonuclease 1
chr1_+_32489426	0.512	NM_005356	LCK	lymphocyte-specific protein tyrosine kinase
chr5_+_140051325	0.511		HARS2	histidyl-tRNA synthetase 2, mitochondrial (putative)
chr19_+_17281374	0.510		DDA1	DET1 and DDB1 associated 1
chr3_-_159872960	0.510	NM_020169	LXN	latexin
chr17_-_12861973	0.510		ELAC2	elaC homolog 2 (E. coli)
chr19_+_39860398	0.509	NM_001012320 NM_018443	ZNF302	zinc finger protein 302
chr4_-_9727558	0.509		WDR1	WD repeat domain 1
chr3_+_120799411	0.508	NM_015900	PLA1A	phospholipase A1 member A
chr10_+_70517823	0.504	NM_002727	SRGN	serglycin
chr9_-_129656581	0.503		ENG	endoglin
chr16_+_31390567	0.502	NM_001042454 NM_001164719	TGFB1I1	transforming growth factor beta 1 induced transcript 1
chr11_+_61316968	0.501		FEN1	flap structure-specific endonuclease 1
chr3_-_49424322	0.501		RHOA	ras homolog gene family, member A
chr1_+_109892741	0.499		GNAI3	guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
chr22_+_37407921	0.499		TOMM22	translocase of outer mitochondrial membrane 22 homolog (yeast)

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.18	2.64e-10	GO:0044260	cellular macromolecule metabolic process
1.24	1.34e-09	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.25	5.16e-08	GO:0090304	nucleic acid metabolic process
1.14	1.98e-06	GO:0043170	macromolecule metabolic process
1.17	1.94e-05	GO:0034641	cellular nitrogen compound metabolic process
1.23	5.00e-05	GO:0010467	gene expression
1.10	5.98e-05	GO:0044237	cellular metabolic process
1.24	6.30e-05	GO:0016070	RNA metabolic process
1.16	9.70e-05	GO:0006807	nitrogen compound metabolic process
1.64	4.88e-04	GO:0071156	regulation of cell cycle arrest
1.33	1.32e-03	GO:0046907	intracellular transport
1.63	1.62e-03	GO:0000075	cell cycle checkpoint
1.37	3.47e-03	GO:0000278	mitotic cell cycle
1.39	3.68e-03	GO:0016071	mRNA metabolic process
1.21	3.75e-03	GO:0034645	cellular macromolecule biosynthetic process
1.21	3.82e-03	GO:0009059	macromolecule biosynthetic process
1.09	4.94e-03	GO:0044238	primary metabolic process
1.63	5.86e-03	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.63	5.86e-03	GO:0000398	nuclear mRNA splicing, via spliceosome
1.50	7.03e-03	GO:0008380	RNA splicing
1.42	7.75e-03	GO:0016032	viral reproduction
1.25	9.16e-03	GO:0051649	establishment of localization in cell
1.60	1.05e-02	GO:0000375	RNA splicing, via transesterification reactions
1.33	1.11e-02	GO:0022403	cell cycle phase
1.31	1.22e-02	GO:0016192	vesicle-mediated transport
1.68	1.51e-02	GO:0000082	G1/S transition of mitotic cell cycle
1.05	1.60e-02	GO:0009987	cellular process
1.23	2.02e-02	GO:0051641	cellular localization
1.28	3.03e-02	GO:0045184	establishment of protein localization
1.41	3.85e-02	GO:0006397	mRNA processing
1.28	3.94e-02	GO:0022402	cell cycle process
1.91	4.61e-02	GO:0051439	regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
1.32	4.78e-02	GO:0051726	regulation of cell cycle

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.08	1.65e-13	GO:0044424	intracellular part
1.11	2.16e-12	GO:0043227	membrane-bounded organelle
1.11	2.58e-12	GO:0043231	intracellular membrane-bounded organelle
1.07	8.22e-12	GO:0005622	intracellular
1.09	8.12e-11	GO:0043229	intracellular organelle
1.09	8.85e-11	GO:0043226	organelle
1.14	1.38e-08	GO:0005634	nucleus
1.09	4.14e-08	GO:0005737	cytoplasm
1.12	1.04e-07	GO:0044444	cytoplasmic part
1.21	3.93e-06	GO:0044428	nuclear part
1.12	7.68e-06	GO:0044446	intracellular organelle part
1.20	2.34e-05	GO:0005829	cytosol
1.11	2.39e-05	GO:0044422	organelle part
1.22	4.63e-05	GO:0031981	nuclear lumen
1.15	4.94e-05	GO:0032991	macromolecular complex
1.18	1.12e-04	GO:0031974	membrane-enclosed lumen
1.18	2.64e-04	GO:0043233	organelle lumen
1.15	5.73e-04	GO:0043234	protein complex
1.03	1.49e-03	GO:0044464	cell part
1.03	1.61e-03	GO:0005623	cell
1.17	1.64e-03	GO:0070013	intracellular organelle lumen
1.19	3.03e-02	GO:0005654	nucleoplasm

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.10	7.66e-07	GO:0005515	protein binding
1.26	3.48e-02	GO:0003723	RNA binding