Motif ID: RUNX1..3.p2

Z-value: 2.824


Transcription factors associated with RUNX1..3.p2:

Gene SymbolEntrez IDGene Name
RUNX1 861 runt-related transcription factor 1
RUNX2 860 runt-related transcription factor 2
RUNX3 864 runt-related transcription factor 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
RUNX3chr1_-_251640610.792.8e-04Click!
RUNX1chr21_-_35182842-0.647.2e-03Click!
RUNX2chr6_+_45498354,
chr6_+_45498262
0.175.3e-01Click!


Activity profile for motif RUNX1..3.p2.

activity profile for motif RUNX1..3.p2


Sorted Z-values histogram for motif RUNX1..3.p2

Sorted Z-values for motif RUNX1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RUNX1..3.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_23754822 10.379 PRKCB
protein kinase C, beta
chr1_-_25164061 9.516 NM_001031680
RUNX3
runt-related transcription factor 3
chr16_+_23754772 9.276 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr17_-_26665220 6.611 NM_006495
EVI2B
ecotropic viral integration site 2B
chr17_-_26665144 6.424 EVI2B
ecotropic viral integration site 2B
chr17_-_26665213 6.281 EVI2B
ecotropic viral integration site 2B
chr17_-_26665194 6.069 EVI2B
ecotropic viral integration site 2B
chr16_+_23754860 5.891 PRKCB
protein kinase C, beta
chr2_-_158008763 5.729 NM_004288
CYTIP
cytohesin 1 interacting protein
chr8_-_102872372 5.549 NCALD
neurocalcin delta
chr8_-_102872354 5.548 NCALD
neurocalcin delta
chr8_-_102872614 5.461 NM_032041
NCALD
neurocalcin delta
chr13_-_45654296 4.582 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_196874759 4.546 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr10_+_70517863 4.500 SRGN
serglycin
chr4_-_71751070 4.479 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr22_+_21116283 4.262


chr9_-_122728173 4.230 TRAF1
TNF receptor-associated factor 1
chr10_+_70517823 4.223 NM_002727
SRGN
serglycin
chr4_-_84254873 4.135 PLAC8
placenta-specific 8

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 3 of 3 entries
enrichment   p-value GO term description
1.75 9.01e-03 GO:0001775 cell activation
1.59 7.53e-03 GO:0006955 immune response
1.50 5.70e-04 GO:0002376 immune system process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 1 of 1 entries
enrichment   p-value GO term description
3.52 2.25e-02 GO:0003823 antigen binding