Motif ID: GTF2A1,2.p2

Z-value: 1.569


Transcription factors associated with GTF2A1,2.p2:

Gene SymbolEntrez IDGene Name
GTF2A1 2957 general transcription factor IIA, 1, 19/37kDa
GTF2A2 2958 general transcription factor IIA, 2, 12kDa

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GTF2A2chr15_-_57736828-0.361.8e-01Click!
GTF2A1chr14_-_80757327-0.214.2e-01Click!


Activity profile for motif GTF2A1,2.p2.

activity profile for motif GTF2A1,2.p2


Sorted Z-values histogram for motif GTF2A1,2.p2

Sorted Z-values for motif GTF2A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2A1,2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_100557098 2.990 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr3_-_147361465 2.930 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr19_+_46416938 2.725 NM_001699
NM_021913
AXL

AXL receptor tyrosine kinase

chr3_-_147361626 2.705 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr21_+_41461597 2.308 NM_012105
NM_138991
NM_138992
BACE2


beta-site APP-cleaving enzyme 2


chr1_-_56817823 2.300 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr12_+_13240868 2.271 NM_001423
EMP1
epithelial membrane protein 1
chr1_-_56817717 2.258 PPAP2B
phosphatidic acid phosphatase type 2B
chr12_+_51777715 2.240 IGFBP6
insulin-like growth factor binding protein 6
chr11_-_111287657 2.196 NM_001885
CRYAB
crystallin, alpha B
chrX_-_3274680 2.162 NM_015419
MXRA5
matrix-remodelling associated 5
chr21_-_27139563 2.154 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr3_+_62279707 2.101 C3orf14
chromosome 3 open reading frame 14
chr11_-_118799452 2.051 NM_006288
THY1
Thy-1 cell surface antigen
chr3_-_147361912 2.003 NM_000935
NM_182943
PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr12_+_79634820 1.975 NM_005593
MYF5
myogenic factor 5
chr15_+_78858763 1.927 NM_018689
KIAA1199
KIAA1199
chr1_-_20682541 1.914


chr21_+_41461924 1.887 BACE2
beta-site APP-cleaving enzyme 2
chr1_-_56817568 1.834 PPAP2B
phosphatidic acid phosphatase type 2B
chr12_+_51777684 1.828 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr21_+_41461962 1.775 BACE2
beta-site APP-cleaving enzyme 2
chr16_+_54072969 1.761 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr8_-_23233426 1.754 LOXL2
lysyl oxidase-like 2
chr17_-_45633873 1.751 COL1A1
collagen, type I, alpha 1
chr17_+_45488330 1.734 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr8_-_18585721 1.703 PSD3
pleckstrin and Sec7 domain containing 3
chr7_-_41709191 1.687 NM_002192
INHBA
inhibin, beta A
chr13_-_44048601 1.651 NM_183422
TSC22D1
TSC22 domain family, member 1
chr21_+_46367216 1.622 COL6A2
collagen, type VI, alpha 2
chr8_-_67687980 1.606 NM_001080416
NM_001144755
MYBL1

LOC645895
v-myb myeloblastosis viral oncogene homolog (avian)-like 1

hypothetical LOC645895
chr1_+_85819004 1.600 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr17_+_45488356 1.571 ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr12_-_74711474 1.567 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr13_-_79810972 1.561 SPRY2
sprouty homolog 2 (Drosophila)
chr21_-_27139143 1.556 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr1_-_56817802 1.539 PPAP2B
phosphatidic acid phosphatase type 2B
chr22_+_31526801 1.463 NM_000362
TIMP3
TIMP metallopeptidase inhibitor 3
chr3_-_78749633 1.431 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr3_+_61522219 1.393 NM_002841
PTPRG
protein tyrosine phosphatase, receptor type, G
chr17_+_1611983 1.390 NM_002615
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr3_-_150569574 1.384 TM4SF1
transmembrane 4 L six family member 1
chr17_-_45633986 1.369 NM_000088
COL1A1
collagen, type I, alpha 1
chr11_+_130745580 1.268 NM_001048209
NTM
neurotrimin
chr2_+_30223253 1.258 NM_001127399
NM_001127400
NM_001127401
NM_016061
YPEL5



yippee-like 5 (Drosophila)



chr2_-_161058120 1.247 RBMS1
RNA binding motif, single stranded interacting protein 1
chr19_-_50601406 1.233 NM_001142502
PPP1R13L
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chrX_-_106130098 1.220 NM_001085354
NM_024657
MORC4

MORC family CW-type zinc finger 4

chr22_+_34107087 1.214 HMOX1
heme oxygenase (decycling) 1
chr15_+_37660568 1.197 NM_003246
THBS1
thrombospondin 1
chr17_+_1612092 1.172 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr9_+_123083540 1.168 GSN
gelsolin
chr3_-_150858274 1.165 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr12_-_7136189 1.145 C1R
complement component 1, r subcomponent
chr11_-_118799058 1.138 THY1
Thy-1 cell surface antigen
chr22_+_34107051 1.135 NM_002133
HMOX1
heme oxygenase (decycling) 1
chr2_+_30223304 1.115 YPEL5
yippee-like 5 (Drosophila)
chr3_+_101694098 1.107 NM_018004
TMEM45A
transmembrane protein 45A
chr21_+_34112456 1.101 ITSN1
intersectin 1 (SH3 domain protein)
chr12_-_7136147 1.082 NM_001733
C1R
complement component 1, r subcomponent
chr1_-_68470585 1.080 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr19_-_48723150 1.079 NM_014297
ETHE1
ethylmalonic encephalopathy 1
chr15_-_88150823 1.043 ANPEP
alanyl (membrane) aminopeptidase
chr17_+_1612056 1.040 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr14_-_54025414 1.030 GMFB
glia maturation factor, beta
chr11_+_13255836 0.983 NM_001030272
NM_001030273
NM_001178
ARNTL


aryl hydrocarbon receptor nuclear translocator-like


chr3_-_48105287 0.982 MAP4
microtubule-associated protein 4
chrX_-_114158388 0.963 NM_000640
IL13RA2
interleukin 13 receptor, alpha 2
chr8_-_145119627 0.947 NM_201378
PLEC
plectin
chr1_+_163084707 0.944 PBX1
pre-B-cell leukemia homeobox 1
chr4_+_41309668 0.941 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr2_+_28469850 0.938 FOSL2
FOS-like antigen 2
chr15_+_30721161 0.936 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr14_+_74815233 0.922 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr12_+_13240987 0.922 EMP1
epithelial membrane protein 1
chr17_+_4795128 0.919 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr7_+_68701704 0.918 NM_001127231
NM_001127232
NM_015570
AUTS2


autism susceptibility candidate 2


chr2_+_30223372 0.914 YPEL5
yippee-like 5 (Drosophila)
chr17_-_1335763 0.913 NM_001080950
MYO1C
myosin IC
chr2_-_210876560 0.911 NM_079422
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr6_-_46401363 0.909 NM_005822
RCAN2
regulator of calcineurin 2
chr15_+_65245546 0.897 NM_001145104
SMAD3
SMAD family member 3
chr9_+_138991775 0.895 NM_000954
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr3_+_101694244 0.892 TMEM45A
transmembrane protein 45A
chr8_-_42184194 0.873 PLAT
plasminogen activator, tissue
chr1_+_63831479 0.871 NM_002633
PGM1
phosphoglucomutase 1
chr11_+_13255948 0.862 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr15_-_75150177 0.859 TSPAN3
tetraspanin 3
chr11_+_13255952 0.858 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr8_-_134378630 0.853 NM_001135242
NM_006096
NDRG1

N-myc downstream regulated 1

chr1_+_203740391 0.847 CDK18
cyclin-dependent kinase 18
chr9_+_115303527 0.842 NM_130795
RGS3
regulator of G-protein signaling 3
chr19_+_46417099 0.842 AXL
AXL receptor tyrosine kinase
chr11_+_13255913 0.837 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr5_+_34723420 0.836 NM_001145523
RAI14
retinoic acid induced 14
chr1_+_161305558 0.834 NM_001113381
RGS4
regulator of G-protein signaling 4
chr13_-_39075200 0.832 LHFP
lipoma HMGIC fusion partner
chr9_+_138991835 0.828 PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr7_-_526005 0.825 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chrX_-_128485134 0.825 NM_003069
NM_139035
SMARCA1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

chr19_+_46416971 0.824 AXL
AXL receptor tyrosine kinase
chr20_-_55718982 0.822 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr19_+_46416975 0.809 AXL
AXL receptor tyrosine kinase
chr1_-_31942206 0.805 NM_001856
COL16A1
collagen, type XVI, alpha 1
chr1_+_78243181 0.801 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr3_-_150578103 0.795 TM4SF1
transmembrane 4 L six family member 1
chr8_+_70541412 0.793 NM_001128204
NM_015170
SULF1

sulfatase 1

chr13_-_44048391 0.793 TSC22D1
TSC22 domain family, member 1
chr7_+_94130673 0.790 PEG10
paternally expressed 10
chr13_-_37070862 0.780 NM_001135934
NM_001135935
NM_001135936
NM_006475
POSTN



periostin, osteoblast specific factor



chr10_-_91092410 0.780 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr22_+_29817315 0.778 SMTN
smoothelin
chr22_-_41372920 0.775 NM_001129819
NM_001171661
NM_007326
CYB5R3


cytochrome b5 reductase 3


chr2_+_28469199 0.774 FOSL2
FOS-like antigen 2
chr1_+_154351162 0.774 LMNA
lamin A/C
chr1_-_219982081 0.773 NM_007207
NM_144729
DUSP10

dual specificity phosphatase 10

chr1_+_154351200 0.761 LMNA
lamin A/C
chr15_-_75150574 0.757 NM_001168412
NM_005724
NM_198902
TSPAN3


tetraspanin 3


chr16_+_22733307 0.752 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr7_-_6490214 0.752 NM_001100603
NM_006854
KDELR2

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2

chr1_+_161305188 0.749 NM_005613
RGS4
regulator of G-protein signaling 4
chr2_-_190635566 0.749 NM_005259
MSTN
myostatin
chr1_-_32940943 0.745 NM_001161708
NM_030786
SYNC

syncoilin, intermediate filament protein

chr11_+_13255925 0.738 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_66827563 0.736 SSH3
slingshot homolog 3 (Drosophila)
chr12_-_45052286 0.732 SLC38A2
solute carrier family 38, member 2
chr2_+_73973640 0.731 ACTG2
actin, gamma 2, smooth muscle, enteric
chr6_+_151688327 0.729 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr3_-_48105637 0.723 NM_001134364
NM_002375
NM_030885
MAP4


microtubule-associated protein 4


chr1_+_21639146 0.722 NM_032264
NBPF3
neuroblastoma breakpoint family, member 3
chr21_+_46370220 0.721 COL6A2
collagen, type VI, alpha 2
chr7_-_150605112 0.719 NM_003078
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr12_-_6321417 0.711 NM_001065
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr1_+_203740306 0.710 NM_002596
NM_212502
NM_212503
CDK18


cyclin-dependent kinase 18


chr1_-_16355013 0.708 NM_004431
EPHA2
EPH receptor A2
chr9_+_2612134 0.703 VLDLR
very low density lipoprotein receptor
chr22_+_29122932 0.702 NM_012429
NM_033382
SEC14L2

SEC14-like 2 (S. cerevisiae)

chr14_-_54025464 0.701 NM_004124
GMFB
glia maturation factor, beta
chr11_+_13255967 0.699 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr10_+_53744043 0.692 NM_012242
DKK1
dickkopf homolog 1 (Xenopus laevis)
chr2_+_73973600 0.685 NM_001615
ACTG2
actin, gamma 2, smooth muscle, enteric
chr19_-_56178882 0.685 NM_139277
NM_005046
KLK7

kallikrein-related peptidase 7

chr2_-_218516950 0.683 NM_022648
TNS1
tensin 1
chr17_+_18566060 0.676 NM_001037330
TRIM16L
tripartite motif containing 16-like
chr19_+_40931285 0.662 NM_019104
LIN37
lin-37 homolog (C. elegans)
chr1_+_39569396 0.658 NM_033044
MACF1
microtubule-actin crosslinking factor 1
chr1_-_207891264 0.658 NM_001017402
LAMB3
laminin, beta 3
chr22_-_36998889 0.656 TMEM184B
transmembrane protein 184B
chr10_-_125841840 0.656 NM_014863
NM_015892
CHST15

carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15

chr12_-_45052830 0.656 NM_018976
SLC38A2
solute carrier family 38, member 2
chr21_-_26175068 0.651 APP
amyloid beta (A4) precursor protein
chr12_-_74711642 0.648 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr22_-_36998615 0.647 NM_001195071
TMEM184B
transmembrane protein 184B
chr7_+_94130752 0.644 PEG10
paternally expressed 10
chr4_-_111777956 0.644 NM_153426
NM_153427
PITX2

paired-like homeodomain 2

chr17_+_64020120 0.636 NM_002734
NM_212472
PRKAR1A

protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)

chr15_+_61127367 0.634 NM_001018008
TPM1
tropomyosin 1 (alpha)
chr7_+_99537065 0.626 NM_004722
AP4M1
adaptor-related protein complex 4, mu 1 subunit
chr22_-_36998912 0.619 NM_001195072
NM_012264
TMEM184B

transmembrane protein 184B

chr19_+_40299058 0.616 FXYD3
FXYD domain containing ion transport regulator 3
chr13_+_109952014 0.612 COL4A2
collagen, type IV, alpha 2
chr22_+_28032950 0.609 NM_006478
NM_152236
NM_152237
GAS2L1


growth arrest-specific 2 like 1


chr2_-_9481035 0.608 ITGB1BP1
integrin beta 1 binding protein 1
chr9_-_5427825 0.607 NM_018465
C9orf46
chromosome 9 open reading frame 46
chr4_+_74500748 0.597 ALB
albumin
chr2_+_200879656 0.597 SPATS2L
spermatogenesis associated, serine-rich 2-like
chr12_-_54392328 0.596 NM_001144997
ITGA7
integrin, alpha 7
chr10_+_121400741 0.594 NM_004281
BAG3
BCL2-associated athanogene 3
chr1_-_219982016 0.593 DUSP10
dual specificity phosphatase 10
chrX_-_106846924 0.592 NM_004089
TSC22D3
TSC22 domain family, member 3
chr9_+_115396020 0.588 NM_144489
RGS3
regulator of G-protein signaling 3
chr13_+_35904408 0.588 NM_001111045
NM_003914
CCNA1

cyclin A1

chr18_+_3402071 0.586 NM_174886
TGIF1
TGFB-induced factor homeobox 1
chr20_-_43889339 0.586 NM_003279
TNNC2
troponin C type 2 (fast)
chr15_-_73792234 0.584 NM_001897
CSPG4
chondroitin sulfate proteoglycan 4
chr1_-_31942142 0.578 COL16A1
collagen, type XVI, alpha 1
chrX_+_70438352 0.571 NM_012278
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr5_-_142057692 0.567 NM_001144934
NM_001144935
FGF1

fibroblast growth factor 1 (acidic)

chr20_-_55718351 0.566 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr4_-_111763655 0.564 NM_000325
PITX2
paired-like homeodomain 2
chr20_+_43875078 0.562 NM_181801
UBE2C
ubiquitin-conjugating enzyme E2C
chr17_-_77602493 0.561 RFNG
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr20_-_43410437 0.556 NM_002999
SDC4
syndecan 4
chr5_-_111340421 0.556 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chrX_-_153290697 0.549 NM_006730
DNASE1L1
deoxyribonuclease I-like 1
chr11_+_13255905 0.546 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr1_+_181380837 0.545 LAMC1
laminin, gamma 1 (formerly LAMB2)
chr2_-_9481038 0.544 NM_004763
NM_022334
ITGB1BP1

integrin beta 1 binding protein 1

chr11_+_32068990 0.541 NM_002901
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr19_-_50518072 0.534 NM_001824
CKM
creatine kinase, muscle
chr2_-_37727472 0.532 CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr3_-_150578207 0.530 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr13_+_31503436 0.527 NM_023037
FRY
furry homolog (Drosophila)
chr11_+_113671744 0.524 NM_006169
NNMT
nicotinamide N-methyltransferase
chr19_-_62028185 0.521 NM_001146186
PEG3
paternally expressed 3
chr4_+_169789327 0.519 NM_001166109
PALLD
palladin, cytoskeletal associated protein
chr12_+_6923441 0.519 NM_138425
C12orf57
chromosome 12 open reading frame 57
chr17_+_64020155 0.518 PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr7_-_136678815 0.517 PTN
pleiotrophin
chr13_-_109757442 0.514 NM_001845
COL4A1
collagen, type IV, alpha 1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.26 2.30e-05 GO:0032501 multicellular organismal process
3.29 9.41e-04 GO:0002576 platelet degranulation
1.30 1.43e-03 GO:0048856 anatomical structure development
1.44 6.12e-03 GO:0009653 anatomical structure morphogenesis
1.25 9.16e-03 GO:0032502 developmental process
1.29 1.13e-02 GO:0048731 system development
3.83 1.78e-02 GO:0050818 regulation of coagulation
2.03 1.95e-02 GO:0010740 positive regulation of intracellular protein kinase cascade
1.25 2.16e-02 GO:0007275 multicellular organismal development
2.42 3.28e-02 GO:0034330 cell junction organization
3.84 3.70e-02 GO:0030193 regulation of blood coagulation
1.98 4.54e-02 GO:0001568 blood vessel development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.65 1.13e-11 GO:0005576 extracellular region
1.68 1.34e-06 GO:0044421 extracellular region part
1.62 4.37e-04 GO:0005615 extracellular space
1.89 3.39e-03 GO:0031012 extracellular matrix
2.16 4.22e-03 GO:0030141 stored secretory granule
3.15 9.88e-03 GO:0031091 platelet alpha granule
3.24 1.23e-02 GO:0031983 vesicle lumen
1.96 2.70e-02 GO:0016323 basolateral plasma membrane
1.20 3.43e-02 GO:0005886 plasma membrane
1.20 3.62e-02 GO:0071944 cell periphery

Nothing significant found in function category.