Motif ID: GTF2A1,2.p2

Z-value: 1.569


Transcription factors associated with GTF2A1,2.p2:

Gene SymbolEntrez IDGene Name
GTF2A1 2957 general transcription factor IIA, 1, 19/37kDa
GTF2A2 2958 general transcription factor IIA, 2, 12kDa

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GTF2A2chr15_-_57736828-0.361.8e-01Click!
GTF2A1chr14_-_80757327-0.214.2e-01Click!


Activity profile for motif GTF2A1,2.p2.

activity profile for motif GTF2A1,2.p2


Sorted Z-values histogram for motif GTF2A1,2.p2

Sorted Z-values for motif GTF2A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2A1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_100557098 2.990 NM_000602
NM_001165413
 SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr3_-_147361465 2.930 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr19_+_46416938 2.725 NM_001699
NM_021913
 AXL

AXL receptor tyrosine kinase

chr3_-_147361626 2.705 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr21_+_41461597 2.308 NM_012105
NM_138991
NM_138992
 BACE2


beta-site APP-cleaving enzyme 2


chr1_-_56817823 2.300 NM_003713
 PPAP2B
phosphatidic acid phosphatase type 2B
chr12_+_13240868 2.271 NM_001423
 EMP1
epithelial membrane protein 1
chr1_-_56817717 2.258 PPAP2B
phosphatidic acid phosphatase type 2B
chr12_+_51777715 2.240 IGFBP6
insulin-like growth factor binding protein 6
chr11_-_111287657 2.196 NM_001885
 CRYAB
crystallin, alpha B
chrX_-_3274680 2.162 NM_015419
 MXRA5
matrix-remodelling associated 5
chr21_-_27139563 2.154 NM_006988
 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr3_+_62279707 2.101 C3orf14
chromosome 3 open reading frame 14
chr11_-_118799452 2.051 NM_006288
 THY1
Thy-1 cell surface antigen
chr3_-_147361912 2.003 NM_000935
NM_182943
 PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr12_+_79634820 1.975 NM_005593
 MYF5
myogenic factor 5
chr15_+_78858763 1.927 NM_018689
 KIAA1199
KIAA1199
chr1_-_20682541 1.914


chr21_+_41461924 1.887 BACE2
beta-site APP-cleaving enzyme 2
chr1_-_56817568 1.834 PPAP2B
phosphatidic acid phosphatase type 2B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
3.84 3.70e-02 GO:0030193 regulation of blood coagulation
3.83 1.78e-02 GO:0050818 regulation of coagulation
3.29 9.41e-04 GO:0002576 platelet degranulation
2.42 3.28e-02 GO:0034330 cell junction organization
2.03 1.95e-02 GO:0010740 positive regulation of intracellular protein kinase cascade
1.98 4.54e-02 GO:0001568 blood vessel development
1.44 6.12e-03 GO:0009653 anatomical structure morphogenesis
1.30 1.43e-03 GO:0048856 anatomical structure development
1.29 1.13e-02 GO:0048731 system development
1.26 2.30e-05 GO:0032501 multicellular organismal process
1.25 9.16e-03 GO:0032502 developmental process
1.25 2.16e-02 GO:0007275 multicellular organismal development

Gene overrepresentation in compartment category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
3.24 1.23e-02 GO:0031983 vesicle lumen
3.15 9.88e-03 GO:0031091 platelet alpha granule
2.16 4.22e-03 GO:0030141 stored secretory granule
1.96 2.70e-02 GO:0016323 basolateral plasma membrane
1.89 3.39e-03 GO:0031012 extracellular matrix
1.68 1.34e-06 GO:0044421 extracellular region part
1.65 1.13e-11 GO:0005576 extracellular region
1.62 4.37e-04 GO:0005615 extracellular space
1.20 3.43e-02 GO:0005886 plasma membrane
1.20 3.62e-02 GO:0071944 cell periphery

Nothing significant found in function category.