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Motif ID: POU1F1.p2

Z-value: 1.078

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_+_74488910	3.581		ALB	albumin
chr4_+_74488947	3.129		ALB	albumin
chr4_+_74500748	2.904		ALB	albumin
chr2_-_88208650	2.882	NM_001443	FABP1	fatty acid binding protein 1, liver
chr4_-_110942783	2.799	NM_000204	CFI	complement factor I
chr4_+_74488835	2.692	NM_000477	ALB	albumin
chr2_-_21079145	2.400		APOB	apolipoprotein B (including Ag(x) antigen)
chr4_-_70115037	2.354	NM_001073	UGT2B11	UDP glucuronosyltransferase 2 family, polypeptide B11
chr4_+_100704262	2.345	NM_000253	MTTP	microsomal triglyceride transfer protein
chrX_-_2892288	2.156	NM_000047	ARSE	arylsulfatase E (chondrodysplasia punctata 1)
chr4_+_74497998	1.939		ALB	albumin
chr12_-_101835183	1.922		PAH	phenylalanine hydroxylase
chr8_-_17797127	1.920	NM_147203 NM_201553 NM_004467 NM_201552	FGL1	fibrinogen-like 1
chr19_-_53081326	1.862		SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr4_+_74520796	1.861	NM_001134	AFP	alpha-fetoprotein
chr16_+_80626331	1.661	NM_002153	HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr16_+_80626456	1.513		HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr1_-_167822248	1.491		F5	coagulation factor V (proaccelerin, labile factor)
chr16_+_80626402	1.471		HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr4_+_155703581	1.458	NM_001184741 NM_005141	FGB	fibrinogen beta chain
chr7_+_137411717	1.445	NM_001190906 NM_001190907 NM_005989	AKR1D1	aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)
chr13_-_47885248	1.424		LPAR6	lysophosphatidic acid receptor 6
chr8_-_19504285	1.386	NM_001130518	CSGALNACT1	chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr14_-_105845570	1.344		IGHA1	immunoglobulin heavy constant alpha 1
chr13_-_47885018	1.327		LPAR6	lysophosphatidic acid receptor 6
chr9_-_122852356	1.315	NM_001735	C5	complement component 5
chr14_-_106249999	1.305		IGHA1	immunoglobulin heavy constant alpha 1
chr3_+_12367993	1.303	NM_015869	PPARG	peroxisome proliferator-activated receptor gamma
chr7_-_87180499	1.262	NM_000927	ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr2_+_143351536	1.243	NM_001032998 NM_003937	KYNU	kynureninase
chr16_-_28528780	1.133	NM_001055 NM_177529	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chrX_+_105823723	1.123	NM_024539	RNF128	ring finger protein 128
chr12_-_101835026	1.115		PAH	phenylalanine hydroxylase
chr3_-_172227152	1.105		SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2
chr6_-_33149244	1.091	NM_033554	HLA-DPA1	major histocompatibility complex, class II, DP alpha 1
chr8_-_28403652	1.076	NM_172366	FBXO16 ZNF395	F-box protein 16 zinc finger protein 395
chr6_-_32742265	1.050	NM_002123	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1
chr4_+_100714995	1.044		MTTP	microsomal triglyceride transfer protein
chr13_-_45577144	1.034	NM_001872 NM_016413	CPB2	carboxypeptidase B2 (plasma)
chr16_-_21221872	1.029	NM_001014444 NM_001888	CRYM	crystallin, mu
chr1_+_178232379	1.016		CEP350	centrosomal protein 350kDa
chr16_-_28528149	0.989	NM_177530 NM_177534	SULT1A1	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr3_+_143824955	0.989	NM_002670	PLS1	plastin 1
chr13_-_45654296	0.984		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr16_+_68156497	0.977	NM_001113178 NM_006599 NM_138713 NM_138714 NM_173214	NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr16_+_80626459	0.927		HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr4_+_74493918	0.924		ALB	albumin
chr1_+_205344200	0.905	NM_000715	C4BPA	complement component 4 binding protein, alpha
chr21_-_42659671	0.891	NM_003225	TFF1	trefoil factor 1
chrX_-_130250880	0.856		IGSF1	immunoglobulin superfamily, member 1
chr6_+_64344307	0.837		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr13_-_45654327	0.833	NM_002298	LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr4_-_71751070	0.830		IGJ	immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr3_+_143858428	0.816	NM_001172312	PLS1	plastin 1
chr19_+_47073029	0.811	NM_001783 NM_021601	CD79A	CD79a molecule, immunoglobulin-associated alpha
chr13_-_45654292	0.787		LCP1	lymphocyte cytosolic protein 1 (L-plastin)
chr6_+_32515596	0.784	NM_019111	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr3_+_195336631	0.761		HES1	hairy and enhancer of split 1, (Drosophila)
chr1_-_41399632	0.760	NM_001031694	SCMH1	sex comb on midleg homolog 1 (Drosophila)
chr3_+_195336625	0.759	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr3_-_122862447	0.756	NM_005335	HCLS1	hematopoietic cell-specific Lyn substrate 1
chrX_-_131375217	0.725	NM_001170701 NM_001170702 NM_001170703	MBNL3	muscleblind-like 3 (Drosophila)
chr18_-_3001944	0.722	NM_014646	LPIN2	lipin 2
chr21_-_31995972	0.722		SCAF4	SR-related CTD-associated factor 4
chr5_-_78318112	0.706	NM_000046	ARSB	arylsulfatase B
chr21_-_14840506	0.681	NM_022136	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1
chr9_-_115877104	0.649		AMBP	alpha-1-microglobulin/bikunin precursor
chr1_+_15862887	0.646
chr19_-_53444733	0.643	NM_001184901 NM_001184903 NM_014959	CARD8	caspase recruitment domain family, member 8
chr7_+_29486010	0.643	NM_001039936	CHN2	chimerin (chimaerin) 2
chr3_+_46594079	0.642	NM_003212	TDGF1	teratocarcinoma-derived growth factor 1
chr17_+_54587882	0.640		PRR11	proline rich 11
chr12_-_8656705	0.632	NM_020661	AICDA	activation-induced cytidine deaminase
chr22_-_43987010	0.623	NM_015264	KIAA0930	KIAA0930
chr14_-_94669547	0.621	NM_001195573	DICER1	dicer 1, ribonuclease type III
chr14_-_105476678	0.607		IGHM	immunoglobulin heavy constant mu
chr6_-_26038817	0.606	NM_005835	SLC17A2	solute carrier family 17 (sodium phosphate), member 2
chr1_+_51855343	0.604		OSBPL9	oxysterol binding protein-like 9
chr6_+_26359805	0.599	NM_003524	HIST1H2BH	histone cluster 1, H2bh
chr1_-_159546348	0.594	NM_000530	MPZ	myelin protein zero
chr3_-_122862391	0.592		HCLS1	hematopoietic cell-specific Lyn substrate 1
chr6_-_33028790	0.588	NM_006120	HLA-DMA	major histocompatibility complex, class II, DM alpha
chr8_-_17811750	0.583		FGL1	fibrinogen-like 1
chr1_-_108032645	0.579	NM_001079874	VAV3	vav 3 guanine nucleotide exchange factor
chr12_+_111829191	0.567		OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa
chr12_+_111829121	0.566	NM_001032409 NM_002534 NM_016816	OAS1	2',5'-oligoadenylate synthetase 1, 40/46kDa
chr4_+_74498042	0.556		ALB	albumin
chr9_-_36266930	0.554	NM_001128227 NM_001190388	GNE	glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr7_+_45899080	0.541		IGFBP1	insulin-like growth factor binding protein 1
chr2_-_171631728	0.538	NM_001136555	TLK1	tousled-like kinase 1
chr4_+_155707089	0.534		FGB	fibrinogen beta chain
chr11_+_30209138	0.532	NM_000510 NM_001018080	FSHB	follicle stimulating hormone, beta polypeptide
chr3_-_195553297	0.524	NM_001080513	CPN2	carboxypeptidase N, polypeptide 2
chr14_-_105681377	0.516		IGHV4-31 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant gamma 1 (G1m marker)
chr17_+_24394043	0.508	NM_016518	PIPOX	pipecolic acid oxidase
chrM_+_12283	0.503
chr6_+_10663934	0.495	NM_001491	GCNT2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr2_+_211166323	0.493	NM_001122634	CPS1	carbamoyl-phosphate synthase 1, mitochondrial
chr5_-_149772469	0.492	NM_001025159 NM_004355 NM_001025158	CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr4_-_151990061	0.483		LRBA	LPS-responsive vesicle trafficking, beach and anchor containing
chr2_+_62754489	0.478	NM_001142615	EHBP1	EH domain binding protein 1
chr14_+_38719462	0.476		PNN	pinin, desmosome associated protein
chr6_-_32665409	0.465	NM_002124	HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr22_-_43986896	0.461		KIAA0930	KIAA0930
chr4_-_110942576	0.457		CFI	complement factor I
chr7_+_45899621	0.455
chr18_-_50776276	0.454	NM_001143829	CCDC68	coiled-coil domain containing 68
chr2_+_68445936	0.449		PLEK	pleckstrin
chr3_+_123256902	0.441	NM_175862	CD86	CD86 molecule
chr20_+_30161173	0.434		TM9SF4	transmembrane 9 superfamily protein member 4
chr10_+_101532544	0.433		ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chrX_-_30505804	0.433	NM_025159	CXorf21	chromosome X open reading frame 21
chr16_+_11966464	0.422	NM_001192	TNFRSF17	tumor necrosis factor receptor superfamily, member 17
chr6_+_32713160	0.422	NM_002122	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1
chr12_-_23628774	0.421	NM_178010	SOX5	SRY (sex determining region Y)-box 5
chr1_-_181826086	0.419		NCF2	neutrophil cytosolic factor 2
chr2_-_121875610	0.410		CLASP1	cytoplasmic linker associated protein 1
chr2_+_37282516	0.409		LOC100505876	hypothetical LOC100505876
chr6_+_31647854	0.406	NM_001159740	LTA	lymphotoxin alpha (TNF superfamily, member 1)
chr1_+_165565006	0.404		POU2F1	POU class 2 homeobox 1
chr4_+_68107039	0.404	NM_012108	STAP1	signal transducing adaptor family member 1
chr2_-_96314148	0.400		SNRNP200	small nuclear ribonucleoprotein 200kDa (U5)
chr10_-_69267774	0.391	NM_021800 NM_201262	DNAJC12	DnaJ (Hsp40) homolog, subfamily C, member 12
chr9_+_99807257	0.391
chrX_-_130251068	0.390	NM_001170961 NM_001170962 NM_001555 NM_205833	IGSF1	immunoglobulin superfamily, member 1
chr3_+_152970904	0.381		LOC201651	arylacetamide deacetylase (esterase) pseudogene
chr4_+_69716298	0.379	NM_001075 NM_001144767	UGT2B10	UDP glucuronosyltransferase 2 family, polypeptide B10
chr7_+_26298136	0.377		SNX10	sorting nexin 10
chr5_+_156628929	0.376	NM_014376	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr6_+_167456230	0.371	NM_031409	CCR6	chemokine (C-C motif) receptor 6
chr10_+_4995453	0.367	NM_001353	AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr19_+_57564981	0.366	NM_001145434	ZNF880	zinc finger protein 880
chr2_+_33592445	0.365	NM_015376	RASGRP3	RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr14_-_19867372	0.364	NM_182852 NM_182851	CCNB1IP1	cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr6_-_22405708	0.364	NM_000948	PRL	prolactin
chr9_-_36365965	0.364		RNF38	ring finger protein 38
chr10_-_5035967	0.360	NM_001135241	AKR1C1 AKR1C2	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chrX_-_19898302	0.354	NM_198279	CXorf23	chromosome X open reading frame 23
chr12_-_69837831	0.353		TSPAN8	tetraspanin 8
chr17_-_59437782	0.352	NM_000873	ICAM2	intercellular adhesion molecule 2
chr2_+_86998248	0.350	NM_001024457	RGPD1	RANBP2-like and GRIP domain containing 1
chr3_-_198784590	0.350	NM_203315	BDH1	3-hydroxybutyrate dehydrogenase, type 1
chr3_-_139960874	0.345	NM_006219	PIK3CB	phosphoinositide-3-kinase, catalytic, beta polypeptide
chr6_+_131936057	0.344	NM_000045	ARG1	arginase, liver
chr14_+_38653177	0.342	NM_001009182 NM_001009183 NM_003616	SIP1	survival of motor neuron protein interacting protein 1
chr10_+_101532450	0.341	NM_000392	ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr4_-_77163609	0.337	NM_001565	CXCL10	chemokine (C-X-C motif) ligand 10
chr1_-_150599105	0.337	NM_001014342	FLG2	filaggrin family member 2
chr2_+_68445821	0.330	NM_002664	PLEK	pleckstrin
chr14_-_105623358	0.326		IGHA1 IGHD IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106170414	0.322		IGHG1 IGHG3	immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr10_+_97505398	0.317	NM_001164178 NM_001164181 NM_001164179 NM_001164182 NM_001164183 NM_001776	ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1
chr6_+_42896771	0.317	NM_015349	KIAA0240	KIAA0240
chr2_-_25954805	0.317	NM_018263	ASXL2	additional sex combs like 2 (Drosophila)
chr1_+_190811479	0.306	NM_002922	RGS1	regulator of G-protein signaling 1
chr4_-_83566045	0.306
chr4_-_83566246	0.303		HNRPDL	heterogeneous nuclear ribonucleoprotein D-like
chr4_-_70547962	0.303	NM_006798	UGT2A1	UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus
chr1_-_101132925	0.302		EXTL2	exostoses (multiple)-like 2
chr2_-_174475528	0.299
chr5_-_149772563	0.298		CD74	CD74 molecule, major histocompatibility complex, class II invariant chain
chr11_-_102250876	0.294	NM_002426	MMP12	matrix metallopeptidase 12 (macrophage elastase)
chr3_+_43303005	0.290	NM_001100594 NM_017719	SNRK	SNF related kinase
chr15_-_54175954	0.289		RFX7	regulatory factor X, 7
chr2_-_74235860	0.281
chr10_+_5478521	0.277	NM_005863	NET1	neuroepithelial cell transforming 1
chr9_+_101717278	0.275		STX17	syntaxin 17
chr10_-_82039158	0.266	NM_000429	MAT1A	methionine adenosyltransferase I, alpha
chr1_-_245120900	0.265		AHCTF1	AT hook containing transcription factor 1
chr1_-_13484119	0.264	NM_001012276	PRAMEF8 PRAMEF7	PRAME family member 8 PRAME family member 7
chrX_+_107569671	0.260	NM_000495 NM_033380	COL4A5	collagen, type IV, alpha 5
chr15_-_32398220	0.255	NM_005135	SLC12A6	solute carrier family 12 (potassium/chloride transporters), member 6
chr5_+_68703036	0.254	NM_133339	RAD17	RAD17 homolog (S. pombe)
chr9_-_5294579	0.254	NM_005059 NM_134441	RLN2	relaxin 2
chr5_+_59819761	0.252		PART1	prostate androgen-regulated transcript 1 (non-protein coding)
chr15_-_53349775	0.252	NM_183234 NM_004580	RAB27A	RAB27A, member RAS oncogene family
chr3_+_46591048	0.252	NM_001174136	TDGF1	teratocarcinoma-derived growth factor 1
chr15_-_43457916	0.251		GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chrX_+_100361588	0.249	NM_001171184 NM_001939	DRP2	dystrophin related protein 2
chr11_+_124329286	0.249		CCDC15	coiled-coil domain containing 15
chr2_+_201464884	0.248	NM_001142356	NIF3L1	NIF3 NGG1 interacting factor 3-like 1 (S. pombe)
chr6_-_109795925	0.247		CD164	CD164 molecule, sialomucin
chr1_+_12046020	0.246	NM_001243	TNFRSF8	tumor necrosis factor receptor superfamily, member 8
chr7_+_106897737	0.242	NM_005295	GPR22	G protein-coupled receptor 22
chr1_+_46151845	0.241		MAST2	microtubule associated serine/threonine kinase 2
chrX_-_39921525	0.237	NM_001123383 NM_001123384	BCOR	BCL6 corepressor
chr13_+_48582389	0.231	NM_014923	FNDC3A	fibronectin type III domain containing 3A
chr7_-_20223467	0.230	NM_182762	MACC1	metastasis associated in colon cancer 1
chrX_+_108665665	0.230	NM_018698	NXT2	nuclear transport factor 2-like export factor 2
chr2_-_203484445	0.229		WDR12	WD repeat domain 12
chr4_-_47831002	0.228	NM_003328	TXK	TXK tyrosine kinase
chr2_+_102136833	0.228	NM_000877	IL1R1	interleukin 1 receptor, type I
chr2_-_88066423	0.226	NM_001024457	RGPD1	RANBP2-like and GRIP domain containing 1
chr18_+_57308754	0.225	NM_031891	CDH20	cadherin 20, type 2
chr9_-_19368815	0.224		RPS6	ribosomal protein S6
chr4_+_9094611	0.223	NM_001040071	LOC650293	seven transmembrane helix receptor
chr19_-_44518516	0.222	NM_004877	GMFG	glia maturation factor, gamma
chr13_-_98708549	0.222	NM_001098200 NM_005292	GPR18	G protein-coupled receptor 18
chr17_-_26665144	0.222		EVI2B	ecotropic viral integration site 2B
chr17_-_26665194	0.217		EVI2B	ecotropic viral integration site 2B

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.96	1.78e-05	GO:0002376	immune system process
2.27	2.51e-05	GO:0006955	immune response
13.86	3.97e-05	GO:0002504	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II
2.42	2.53e-03	GO:0050776	regulation of immune response
5.86	2.80e-03	GO:0019882	antigen processing and presentation
4.24	3.15e-03	GO:0002429	immune response-activating cell surface receptor signaling pathway
4.12	4.64e-03	GO:0002768	immune response-regulating cell surface receptor signaling pathway
4.31	5.64e-03	GO:0050851	antigen receptor-mediated signaling pathway
2.58	3.14e-02	GO:0050778	positive regulation of immune response

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
15.84	1.57e-06	GO:0042613	MHC class II protein complex
9.24	1.25e-05	GO:0042611	MHC protein complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
6.24	3.54e-03	GO:0003823	antigen binding
13.86	3.80e-02	GO:0032395	MHC class II receptor activity