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• Activity deltas table
• Regulatory interactions
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Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 1.139

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_60663842	1.695	NM_020928	ZSWIM6	zinc finger, SWIM-type containing 6
chr5_-_172688024	1.296		STC2	stanniocalcin 2
chr5_-_172687798	1.290		STC2	stanniocalcin 2
chr1_+_85819004	1.011	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr3_-_65999548	0.997	NM_001033057 NM_004742 NM_015520	MAGI1	membrane associated guanylate kinase, WW and PDZ domain containing 1
chr18_-_21184824	0.937
chr6_-_163754903	0.911		LOC100526820	hypothetical LOC100526820
chr1_+_219119468	0.833		HLX	H2.0-like homeobox
chr20_-_10602429	0.819	NM_000214	JAG1	jagged 1
chr21_-_35182842	0.807	NM_001001890 NM_001122607	RUNX1	runt-related transcription factor 1
chr10_+_94439658	0.796	NM_002729	HHEX	hematopoietically expressed homeobox
chr7_-_27136876	0.794	NM_002141	HOXA4	homeobox A4
chr21_-_35182873	0.790		RUNX1	runt-related transcription factor 1
chr19_-_2378581	0.776		TIMM13	translocase of inner mitochondrial membrane 13 homolog (yeast)
chr12_-_74710741	0.773		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr1_+_219119623	0.757		HLX	H2.0-like homeobox
chr2_-_101291483	0.745	NM_173647	RNF149	ring finger protein 149
chr18_-_24011349	0.741	NM_001792	CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr2_-_219791638	0.738		ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr19_-_2378530	0.737		TIMM13	translocase of inner mitochondrial membrane 13 homolog (yeast)
chr4_-_57671273	0.724	NM_001553	IGFBP7	insulin-like growth factor binding protein 7
chr4_-_57671307	0.720		IGFBP7	insulin-like growth factor binding protein 7
chr14_+_73073570	0.719	NM_001037161	ACOT1	acyl-CoA thioesterase 1
chr10_+_102782151	0.711		SFXN3	sideroflexin 3
chr13_+_92677012	0.688	NM_005708	GPC6	glypican 6
chr4_-_57671112	0.688		IGFBP7	insulin-like growth factor binding protein 7
chr13_-_32822759	0.659		STARD13	StAR-related lipid transfer (START) domain containing 13
chr2_-_219791902	0.655	NM_005689	ABCB6	ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr16_-_86082818	0.655	NM_015144	ZCCHC14	zinc finger, CCHC domain containing 14
chr9_-_13269562	0.644		MPDZ	multiple PDZ domain protein
chr14_-_73106243	0.624
chr1_-_85703321	0.622	NM_012137	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr11_+_72696963	0.618		ARHGEF17	Rho guanine nucleotide exchange factor (GEF) 17
chr2_+_200879737	0.613		SPATS2L	spermatogenesis associated, serine-rich 2-like
chr9_-_25668230	0.611		TUSC1	tumor suppressor candidate 1
chr4_-_103967784	0.610	NM_181887 NM_181891	UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr2_+_200879656	0.609		SPATS2L	spermatogenesis associated, serine-rich 2-like
chr20_+_11819364	0.606	NM_181443	BTBD3	BTB (POZ) domain containing 3
chr3_+_30623376	0.601		TGFBR2	transforming growth factor, beta receptor II (70/80kDa)
chr16_+_30617962	0.580	NM_006662	SRCAP	Snf2-related CREBBP activator protein
chr15_-_27901828	0.576	NM_003257 NM_175610	TJP1	tight junction protein 1 (zona occludens 1)
chr3_+_189354167	0.573	NM_001167672	LPP	LIM domain containing preferred translocation partner in lipoma
chr16_+_81218142	0.570		CDH13	cadherin 13, H-cadherin (heart)
chr18_-_5533967	0.558	NM_012307	EPB41L3	erythrocyte membrane protein band 4.1-like 3
chr5_-_172689111	0.554	NM_003714	STC2	stanniocalcin 2
chr10_+_102782156	0.550		SFXN3	sideroflexin 3
chr15_+_65145248	0.544	NM_005902	SMAD3	SMAD family member 3
chr5_+_151131709	0.536		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr6_+_3696224	0.536
chr17_-_39211706	0.528	NM_004090	DUSP3	dual specificity phosphatase 3
chr5_+_151131704	0.527		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr5_+_151131707	0.526		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr1_+_1437734	0.513	NM_001170536	ATAD3A	ATPase family, AAA domain containing 3A
chr1_-_85816520	0.513	NM_001134445	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr15_+_64782468	0.511		SMAD6	SMAD family member 6
chr9_-_83494198	0.508		TLE1	transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr1_-_85703198	0.503		DDAH1	dimethylarginine dimethylaminohydrolase 1
chr14_+_73105618	0.502		ACOT2	acyl-CoA thioesterase 2
chr16_+_81218074	0.501	NM_001257	CDH13	cadherin 13, H-cadherin (heart)
chr2_-_45090025	0.500	NM_016932	SIX2	SIX homeobox 2
chr15_+_65145215	0.497		SMAD3	SMAD family member 3
chr2_+_20510312	0.496	NM_004040	RHOB	ras homolog gene family, member B
chr1_+_181258952	0.492	NM_002293	LAMC1	laminin, gamma 1 (formerly LAMB2)
chr19_-_61680510	0.491	NM_022103	ZNF667	zinc finger protein 667
chr2_+_219283751	0.491	NM_014640	TTLL4	tubulin tyrosine ligase-like family, member 4
chr8_-_103737058	0.490	NM_005655	KLF10	Kruppel-like factor 10
chr1_-_223907283	0.490	NM_001008493 NM_018212	ENAH	enabled homolog (Drosophila)
chr22_-_27405708	0.489	NM_001145418	TTC28	tetratricopeptide repeat domain 28
chr3_-_31998241	0.482	NM_001174060 NM_017784	OSBPL10	oxysterol binding protein-like 10
chr12_-_88269884	0.480		DUSP6	dual specificity phosphatase 6
chr19_+_1358531	0.480	NM_018959 NM_170711	DAZAP1	DAZ associated protein 1
chr1_+_6767968	0.479	NM_001195563 NM_015215	CAMTA1	calmodulin binding transcription activator 1
chr12_+_50731457	0.471	NM_002135 NM_173157	NR4A1	nuclear receptor subfamily 4, group A, member 1
chr8_+_126511739	0.470	NM_025195	TRIB1	tribbles homolog 1 (Drosophila)
chr17_+_76988134	0.469	NM_001080519	BAHCC1	BAH domain and coiled-coil containing 1
chr9_-_85342868	0.468	NM_174938	FRMD3	FERM domain containing 3
chr3_-_151171190	0.458	NM_002628 NM_053024	PFN2	profilin 2
chr5_-_133368326	0.456		VDAC1	voltage-dependent anion channel 1
chr11_-_118286822	0.450	NM_182557	BCL9L	B-cell CLL/lymphoma 9-like
chr14_+_54102518	0.448		LOC644925	hypothetical LOC644925
chr17_+_52026058	0.448	NM_005450	NOG	noggin
chr4_+_38341982	0.447	NM_016531	KLF3	Kruppel-like factor 3 (basic)
chr14_-_60185659	0.445	NM_005982	SIX1	SIX homeobox 1
chr9_+_98252200	0.445	NM_014282	HABP4	hyaluronan binding protein 4
chr16_-_65774904	0.442		KIAA0895L	KIAA0895-like
chr16_-_65775326	0.440	NM_001040715	KIAA0895L	KIAA0895-like
chr17_+_43127628	0.436	NM_014726	TBKBP1	TBK1 binding protein 1
chr1_-_203916160	0.433		SLC45A3	solute carrier family 45, member 3
chr7_-_131911768	0.432		PLXNA4	plexin A4
chr20_-_10602139	0.432		JAG1	jagged 1
chr1_-_92124064	0.430		TGFBR3	transforming growth factor, beta receptor III
chr15_+_37660568	0.429	NM_003246	THBS1	thrombospondin 1
chr4_-_141568210	0.428	NM_001130675 NM_004362	CLGN	calmegin
chr12_+_64504835	0.427		HMGA2	high mobility group AT-hook 2
chr16_-_4263056	0.426		TFAP4	transcription factor AP-4 (activating enhancer binding protein 4)
chr19_+_50663089	0.423	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr5_+_151131655	0.422	NM_005754 NM_198395	G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr7_+_16652282	0.420	NM_001159767 NM_014038	BZW2	basic leucine zipper and W2 domains 2
chr10_+_99248605	0.419	NM_024954	UBTD1	ubiquitin domain containing 1
chr7_-_5429702	0.419	NM_001080495	TNRC18	trinucleotide repeat containing 18
chr6_-_86409701	0.416	NM_001159677 NM_006372	SYNCRIP	synaptotagmin binding, cytoplasmic RNA interacting protein
chr5_+_151131676	0.416		G3BP1	GTPase activating protein (SH3 domain) binding protein 1
chr10_+_114700775	0.412		TCF7L2	transcription factor 7-like 2 (T-cell specific, HMG-box)
chr5_-_133368313	0.412		VDAC1	voltage-dependent anion channel 1
chr5_-_133368335	0.406		VDAC1	voltage-dependent anion channel 1
chr1_+_219119358	0.400	NM_021958	HLX	H2.0-like homeobox
chr15_-_27901628	0.398		TJP1	tight junction protein 1 (zona occludens 1)
chr3_-_162305319	0.397	NM_033169 NM_001038628 NM_003781 NM_033167 NM_033168	B3GALNT1	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr1_-_203916239	0.397	NM_033102	SLC45A3	solute carrier family 45, member 3
chr8_+_42871176	0.397	NM_032410	HOOK3	hook homolog 3 (Drosophila)
chr4_-_103968104	0.397	NM_003340 NM_181886 NM_181888 NM_181889	UBE2D3	ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
chr3_-_71715431	0.392	NM_001012505 NM_032682	FOXP1	forkhead box P1
chr3_-_71196696	0.392		FOXP1	forkhead box P1
chr6_+_144649142	0.389		UTRN	utrophin
chr19_+_1358664	0.389		DAZAP1	DAZ associated protein 1
chr2_-_73313823	0.388	NM_032319	C2orf7	chromosome 2 open reading frame 7
chr8_+_69026895	0.388		PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr2_-_40532651	0.388		SLC8A1	solute carrier family 8 (sodium/calcium exchanger), member 1
chr3_+_195336625	0.388	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr1_-_925215	0.387		HES4	hairy and enhancer of split 4 (Drosophila)
chr10_+_102749597	0.386		LZTS2	leucine zipper, putative tumor suppressor 2
chr19_+_748444	0.386		PTBP1	polypyrimidine tract binding protein 1
chr8_+_42871299	0.385		HOOK3	hook homolog 3 (Drosophila)
chr7_-_5535726	0.384		ACTB	actin, beta
chr15_-_80123935	0.383		MEX3B	mex-3 homolog B (C. elegans)
chr20_+_21231921	0.381	NM_012255	XRN2	5'-3' exoribonuclease 2
chr14_+_32478209	0.380	NM_001164749 NM_001165893 NM_022123 NM_173159	NPAS3	neuronal PAS domain protein 3
chr3_+_195336631	0.380		HES1	hairy and enhancer of split 1, (Drosophila)
chr1_+_1437400	0.380		ATAD3A ATAD3B	ATPase family, AAA domain containing 3A ATPase family, AAA domain containing 3B
chr1_+_181259317	0.377
chr10_+_102749222	0.377		LZTS2	leucine zipper, putative tumor suppressor 2
chr14_-_68515791	0.375	NM_001102 NM_001130004 NM_001130005	ACTN1	actinin, alpha 1
chrX_-_128616594	0.374	NM_017413	APLN	apelin
chr16_-_4263001	0.370	NM_003223	TFAP4	transcription factor AP-4 (activating enhancer binding protein 4)
chr14_-_68515742	0.369		ACTN1	actinin, alpha 1
chr5_-_133368279	0.369		VDAC1	voltage-dependent anion channel 1
chr3_-_151171576	0.368		PFN2	profilin 2
chr5_-_142763481	0.362		NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr8_+_42871244	0.362		HOOK3	hook homolog 3 (Drosophila)
chr2_-_160972606	0.362		RBMS1	RNA binding motif, single stranded interacting protein 1
chr1_+_1397021	0.361	NM_031921	ATAD3B	ATPase family, AAA domain containing 3B
chr22_-_34754343	0.361	NM_001082578 NM_001082579	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr14_-_68515731	0.360		ACTN1	actinin, alpha 1
chr5_-_142763252	0.360		NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr5_-_133368288	0.359		VDAC1	voltage-dependent anion channel 1
chr14_-_53491019	0.358	NM_130851	BMP4	bone morphogenetic protein 4
chr19_+_748448	0.357		PTBP1	polypyrimidine tract binding protein 1
chr14_-_68515727	0.357		ACTN1	actinin, alpha 1
chr10_-_99248355	0.354	NM_022362	MMS19	MMS19 nucleotide excision repair homolog (S. cerevisiae)
chr3_+_31998269	0.353	NM_001137674	ZNF860	zinc finger protein 860
chr1_+_61320213	0.353	NM_001134673 NM_005595	NFIA	nuclear factor I/A
chr3_-_135575925	0.350	NM_016201	AMOTL2	angiomotin like 2
chr12_-_87498225	0.348	NM_000899 NM_003994	KITLG	KIT ligand
chrX_+_110811001	0.347	NM_001039210 NM_001099922 NM_001168385 NM_018466	ALG13	asparagine-linked glycosylation 13 homolog (S. cerevisiae)
chr5_-_133368257	0.342		VDAC1	voltage-dependent anion channel 1
chr14_-_68515761	0.340		ACTN1	actinin, alpha 1
chr9_-_94472090	0.339		IPPK	inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr14_-_22521544	0.339	NM_032876	JUB	jub, ajuba homolog (Xenopus laevis)
chr2_+_36436873	0.339	NM_016441	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr3_-_31997738	0.338		OSBPL10	oxysterol binding protein-like 10
chr1_+_219119430	0.338		HLX	H2.0-like homeobox
chr5_+_154218269	0.337		CNOT8	CCR4-NOT transcription complex, subunit 8
chr3_+_151171755	0.336		LOC646903	hypothetical LOC646903
chr11_+_113436438	0.332	NM_001018011	ZBTB16	zinc finger and BTB domain containing 16
chr21_+_45649719	0.332
chr11_+_72697310	0.332	NM_014786	ARHGEF17	Rho guanine nucleotide exchange factor (GEF) 17
chr20_+_43952997	0.331	NM_000308 NM_001127695 NM_001167594	CTSA	cathepsin A
chr7_-_131911808	0.327	NM_001105543 NM_020911	PLXNA4	plexin A4
chr9_+_35479989	0.326	NM_014806	RUSC2	RUN and SH3 domain containing 2
chr19_-_1352474	0.325	NM_000156 NM_138924	GAMT	guanidinoacetate N-methyltransferase
chr9_-_98457407	0.325	NM_153698	C9orf21	chromosome 9 open reading frame 21
chr14_-_68515701	0.324		ACTN1	actinin, alpha 1
chr4_-_129428414	0.322		PGRMC2	progesterone receptor membrane component 2
chr17_+_75625025	0.321	NM_017950	CCDC40	coiled-coil domain containing 40
chr3_-_189354510	0.321		LOC339929	hypothetical LOC339929
chr4_-_129428378	0.320		PGRMC2	progesterone receptor membrane component 2
chr18_+_75540831	0.319		CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr5_-_142763393	0.318		NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr10_+_17311282	0.318		VIM	vimentin
chr17_-_60088773	0.317	NM_022739	SMURF2	SMAD specific E3 ubiquitin protein ligase 2
chr2_-_144991386	0.316		ZEB2	zinc finger E-box binding homeobox 2
chr8_-_42870779	0.316	NM_001160223 NM_001160224 NM_001160225 NM_030954	RNF170	ring finger protein 170
chr10_+_17311242	0.315		VIM	vimentin
chr3_-_38666122	0.311	NM_000335 NM_001099404 NM_001099405 NM_198056 NM_001160160 NM_001160161	SCN5A	sodium channel, voltage-gated, type V, alpha subunit
chr10_+_17311307	0.310		VIM	vimentin
chr6_-_85530617	0.308	NM_001080508	TBX18	T-box 18
chr3_-_49424413	0.307		RHOA	ras homolog gene family, member A
chr4_-_140696740	0.306	NM_030648	SETD7	SET domain containing (lysine methyltransferase) 7
chr20_+_56397568	0.305	NM_001195677 NM_004738	VAPB	VAMP (vesicle-associated membrane protein)-associated protein B and C
chr5_+_52131686	0.304		PELO	pelota homolog (Drosophila)
chr2_+_200879040	0.304	NM_001100422 NM_001100424 NM_001100423	SPATS2L	spermatogenesis associated, serine-rich 2-like
chr17_-_60208083	0.303		LOC146880	hypothetical LOC146880
chr3_+_157875063	0.303		TIPARP	TCDD-inducible poly(ADP-ribose) polymerase
chr19_+_748452	0.302		PTBP1	polypyrimidine tract binding protein 1
chr12_-_106011715	0.301	NM_004075	CRY1	cryptochrome 1 (photolyase-like)
chr7_+_128257698	0.301	NM_001127487 NM_001458	FLNC	filamin C, gamma
chr5_-_142763418	0.301	NM_000176 NM_001020825 NM_001024094	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr10_+_17311283	0.300		VIM	vimentin
chr11_+_799985	0.300		RPLP2	ribosomal protein, large, P2
chr22_-_17891777	0.299		CLDN5	claudin 5

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.14	1.57e-14	GO:0009987	cellular process
1.31	6.53e-13	GO:0044260	cellular macromolecule metabolic process
1.24	1.08e-12	GO:0044237	cellular metabolic process
1.22	1.53e-12	GO:0050794	regulation of cellular process
1.36	1.92e-12	GO:0060255	regulation of macromolecule metabolic process
1.20	1.84e-11	GO:0050789	regulation of biological process
1.34	2.56e-11	GO:0031323	regulation of cellular metabolic process
1.19	3.64e-11	GO:0065007	biological regulation
1.32	9.47e-11	GO:0032502	developmental process
1.55	1.99e-10	GO:0007399	nervous system development
1.32	4.27e-10	GO:0080090	regulation of primary metabolic process
1.30	4.94e-10	GO:0019222	regulation of metabolic process
1.32	1.13e-09	GO:0007275	multicellular organismal development
1.52	2.35e-09	GO:0009653	anatomical structure morphogenesis
1.32	5.31e-09	GO:0016043	cellular component organization
1.30	1.33e-08	GO:0071840	cellular component organization or biogenesis
1.18	1.45e-08	GO:0008152	metabolic process
1.55	1.62e-08	GO:0009893	positive regulation of metabolic process
1.40	2.10e-08	GO:0048523	negative regulation of cellular process
1.24	2.27e-08	GO:0043170	macromolecule metabolic process
1.35	2.53e-08	GO:0048518	positive regulation of biological process
1.32	2.59e-08	GO:0048856	anatomical structure development
1.34	3.49e-08	GO:0048731	system development
1.19	6.01e-08	GO:0044238	primary metabolic process
1.35	8.03e-08	GO:0071842	cellular component organization at cellular level
1.33	1.61e-07	GO:0071841	cellular component organization or biogenesis at cellular level
1.30	1.64e-07	GO:0034641	cellular nitrogen compound metabolic process
1.36	2.87e-07	GO:0048519	negative regulation of biological process
1.61	4.00e-07	GO:0022008	neurogenesis
1.53	4.67e-07	GO:0031325	positive regulation of cellular metabolic process
1.53	4.92e-07	GO:0010604	positive regulation of macromolecule metabolic process
1.35	6.64e-07	GO:0048522	positive regulation of cellular process
1.76	7.99e-07	GO:0000902	cell morphogenesis
1.62	8.99e-07	GO:0048699	generation of neurons
1.40	9.18e-07	GO:0006464	protein modification process
1.40	1.05e-06	GO:0010467	gene expression
1.43	1.54e-06	GO:0023051	regulation of signaling
1.28	1.61e-06	GO:0006807	nitrogen compound metabolic process
1.31	1.65e-06	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.72	1.76e-06	GO:0032989	cellular component morphogenesis
1.33	1.80e-06	GO:0044267	cellular protein metabolic process
1.37	1.87e-06	GO:0048869	cellular developmental process
1.56	2.00e-06	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.55	2.09e-06	GO:0032268	regulation of cellular protein metabolic process
1.52	4.09e-06	GO:0051246	regulation of protein metabolic process
1.36	4.92e-06	GO:0030154	cell differentiation
1.57	5.64e-06	GO:0048468	cell development
1.79	6.95e-06	GO:0000904	cell morphogenesis involved in differentiation
1.30	1.61e-05	GO:0009889	regulation of biosynthetic process
1.65	1.65e-05	GO:0045595	regulation of cell differentiation
1.43	1.66e-05	GO:0009966	regulation of signal transduction
1.36	2.13e-05	GO:0043412	macromolecule modification
1.30	2.41e-05	GO:0031326	regulation of cellular biosynthetic process
1.54	2.62e-05	GO:0050793	regulation of developmental process
1.30	2.85e-05	GO:0010468	regulation of gene expression
1.31	3.81e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.56	3.85e-05	GO:0009891	positive regulation of biosynthetic process
2.62	3.89e-05	GO:0006469	negative regulation of protein kinase activity
1.30	4.39e-05	GO:0010556	regulation of macromolecule biosynthetic process
2.92	8.07e-05	GO:0060485	mesenchyme development
1.59	8.41e-05	GO:0010557	positive regulation of macromolecule biosynthetic process
1.57	1.02e-04	GO:0051173	positive regulation of nitrogen compound metabolic process
1.54	1.13e-04	GO:0031328	positive regulation of cellular biosynthetic process
1.60	1.26e-04	GO:0019220	regulation of phosphate metabolic process
1.60	1.26e-04	GO:0051174	regulation of phosphorus metabolic process
1.61	1.31e-04	GO:0010628	positive regulation of gene expression
1.57	1.35e-04	GO:2000026	regulation of multicellular organismal development
1.62	1.51e-04	GO:0007167	enzyme linked receptor protein signaling pathway
2.49	1.89e-04	GO:0033673	negative regulation of kinase activity
1.62	2.09e-04	GO:0001932	regulation of protein phosphorylation
2.41	2.12e-04	GO:0060537	muscle tissue development
1.60	2.38e-04	GO:0042325	regulation of phosphorylation
1.42	2.41e-04	GO:0051641	cellular localization
1.56	2.56e-04	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.54	3.27e-04	GO:0031399	regulation of protein modification process
1.73	3.75e-04	GO:0023057	negative regulation of signaling
1.60	3.79e-04	GO:0030030	cell projection organization
1.76	3.80e-04	GO:0009968	negative regulation of signal transduction
1.46	3.87e-04	GO:0010646	regulation of cell communication
1.71	3.97e-04	GO:0045859	regulation of protein kinase activity
1.30	4.90e-04	GO:0051252	regulation of RNA metabolic process
1.60	5.27e-04	GO:0045893	positive regulation of transcription, DNA-dependent
1.30	5.81e-04	GO:0090304	nucleic acid metabolic process
2.52	6.43e-04	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
2.99	6.67e-04	GO:0014031	mesenchymal cell development
1.34	7.16e-04	GO:0016070	RNA metabolic process
1.85	8.10e-04	GO:0001501	skeletal system development
1.71	8.38e-04	GO:0010648	negative regulation of cell communication
2.35	1.00e-03	GO:0051348	negative regulation of transferase activity
1.26	1.04e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.46	1.11e-03	GO:0009892	negative regulation of metabolic process
1.48	1.12e-03	GO:0031324	negative regulation of cellular metabolic process
1.68	1.21e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.79	1.29e-03	GO:0018193	peptidyl-amino acid modification
1.56	1.37e-03	GO:0051254	positive regulation of RNA metabolic process
1.68	1.50e-03	GO:0048646	anatomical structure formation involved in morphogenesis
1.66	1.51e-03	GO:0043549	regulation of kinase activity
1.83	1.53e-03	GO:0060284	regulation of cell development
1.54	2.20e-03	GO:0030182	neuron differentiation
1.25	2.20e-03	GO:0051171	regulation of nitrogen compound metabolic process
2.37	2.29e-03	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.46	2.42e-03	GO:0010605	negative regulation of macromolecule metabolic process
1.68	2.56e-03	GO:0051094	positive regulation of developmental process
1.53	3.18e-03	GO:0009890	negative regulation of biosynthetic process
2.78	3.45e-03	GO:0048762	mesenchymal cell differentiation
1.64	3.92e-03	GO:0072358	cardiovascular system development
1.64	3.92e-03	GO:0072359	circulatory system development
1.62	4.22e-03	GO:0007417	central nervous system development
1.77	4.47e-03	GO:0045597	positive regulation of cell differentiation
3.66	4.49e-03	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway
2.31	4.50e-03	GO:0014706	striated muscle tissue development
1.83	4.51e-03	GO:0001944	vasculature development
1.62	4.70e-03	GO:0048858	cell projection morphogenesis
1.33	4.91e-03	GO:0006996	organelle organization
1.52	5.25e-03	GO:0031327	negative regulation of cellular biosynthetic process
1.83	5.66e-03	GO:0071900	regulation of protein serine/threonine kinase activity
1.52	5.90e-03	GO:0009790	embryo development
1.40	6.53e-03	GO:0051649	establishment of localization in cell
1.60	6.99e-03	GO:0032990	cell part morphogenesis
1.85	7.40e-03	GO:0001568	blood vessel development
1.45	7.47e-03	GO:0009888	tissue development
1.27	7.57e-03	GO:0006355	regulation of transcription, DNA-dependent
1.60	7.71e-03	GO:0051338	regulation of transferase activity
1.58	7.93e-03	GO:0051253	negative regulation of RNA metabolic process
1.60	8.59e-03	GO:0048585	negative regulation of response to stimulus
1.52	9.09e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.46	9.86e-03	GO:0051128	regulation of cellular component organization
1.31	1.01e-02	GO:0034645	cellular macromolecule biosynthetic process
1.44	1.20e-02	GO:0006351	transcription, DNA-dependent
1.31	1.26e-02	GO:0009059	macromolecule biosynthetic process
1.65	1.27e-02	GO:0008285	negative regulation of cell proliferation
1.80	1.32e-02	GO:0061061	muscle structure development
1.22	1.43e-02	GO:0019538	protein metabolic process
1.52	1.44e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.25	1.50e-02	GO:0044249	cellular biosynthetic process
1.91	1.58e-02	GO:0048514	blood vessel morphogenesis
1.53	1.65e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.56	1.75e-02	GO:0045892	negative regulation of transcription, DNA-dependent
1.28	1.81e-02	GO:0048513	organ development
1.40	1.94e-02	GO:0032879	regulation of localization
2.82	1.96e-02	GO:0017015	regulation of transforming growth factor beta receptor signaling pathway
1.52	2.24e-02	GO:0009887	organ morphogenesis
1.77	2.27e-02	GO:0051270	regulation of cellular component movement
1.52	2.65e-02	GO:0010629	negative regulation of gene expression
3.15	2.70e-02	GO:0030509	BMP signaling pathway
1.51	2.97e-02	GO:0051172	negative regulation of nitrogen compound metabolic process
1.40	3.10e-02	GO:0032774	RNA biosynthetic process
1.34	3.13e-02	GO:0051239	regulation of multicellular organismal process
1.77	3.13e-02	GO:0010608	posttranscriptional regulation of gene expression
1.44	3.49e-02	GO:0046907	intracellular transport
1.60	3.84e-02	GO:0048667	cell morphogenesis involved in neuron differentiation
1.49	4.42e-02	GO:0006396	RNA processing
1.63	4.48e-02	GO:0000122	negative regulation of transcription from RNA polymerase II promoter

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.16	5.74e-24	GO:0005622	intracellular
1.15	2.09e-20	GO:0044424	intracellular part
1.28	1.92e-16	GO:0005634	nucleus
1.16	4.21e-16	GO:0043226	organelle
1.16	9.60e-16	GO:0043229	intracellular organelle
1.18	8.61e-15	GO:0043231	intracellular membrane-bounded organelle
1.18	9.16e-15	GO:0043227	membrane-bounded organelle
1.18	9.64e-13	GO:0005737	cytoplasm
1.35	1.66e-07	GO:0070013	intracellular organelle lumen
1.36	2.33e-07	GO:0044428	nuclear part
1.34	2.80e-07	GO:0031974	membrane-enclosed lumen
1.34	3.99e-07	GO:0043233	organelle lumen
1.37	1.39e-06	GO:0031981	nuclear lumen
1.17	6.29e-06	GO:0044444	cytoplasmic part
1.17	1.28e-05	GO:0044446	intracellular organelle part
1.17	1.72e-05	GO:0044422	organelle part
1.41	2.48e-05	GO:0005654	nucleoplasm
1.32	2.61e-05	GO:0005829	cytosol
1.55	5.50e-05	GO:0044451	nucleoplasm part
1.05	6.91e-05	GO:0044464	cell part
1.05	7.22e-05	GO:0005623	cell
1.21	3.34e-04	GO:0032991	macromolecular complex
4.76	1.14e-03	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.20	1.03e-02	GO:0043234	protein complex
1.21	1.09e-02	GO:0043228	non-membrane-bounded organelle
1.21	1.09e-02	GO:0043232	intracellular non-membrane-bounded organelle
1.49	2.35e-02	GO:0030529	ribonucleoprotein complex
1.85	2.94e-02	GO:0030424	axon

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.21	7.97e-15	GO:0005515	protein binding
1.12	1.64e-13	GO:0005488	binding
1.40	3.83e-10	GO:0000166	nucleotide binding
1.54	6.48e-07	GO:0030528	transcription regulator activity
1.26	3.27e-06	GO:0003676	nucleic acid binding
1.57	6.43e-05	GO:0043565	sequence-specific DNA binding
1.31	2.56e-04	GO:0035639	purine ribonucleoside triphosphate binding
1.48	3.78e-04	GO:0003723	RNA binding
1.30	6.65e-04	GO:0017076	purine nucleotide binding
1.30	8.07e-04	GO:0032553	ribonucleotide binding
1.30	8.07e-04	GO:0032555	purine ribonucleotide binding
1.42	1.30e-03	GO:0001071	nucleic acid binding transcription factor activity
1.42	1.30e-03	GO:0003700	sequence-specific DNA binding transcription factor activity
1.78	1.83e-03	GO:0008134	transcription factor binding
1.73	2.84e-03	GO:0016563	transcription activator activity
1.89	6.53e-03	GO:0000975	regulatory region DNA binding
1.89	6.53e-03	GO:0001067	regulatory region nucleic acid binding
1.89	6.53e-03	GO:0044212	transcription regulatory region DNA binding
1.71	6.94e-03	GO:0016564	transcription repressor activity
1.30	1.20e-02	GO:0005524	ATP binding
1.28	1.89e-02	GO:0030554	adenyl nucleotide binding
2.94	1.96e-02	GO:0046332	SMAD binding
1.85	2.28e-02	GO:0010843	promoter binding
1.22	2.48e-02	GO:0003677	DNA binding
1.28	2.50e-02	GO:0032559	adenyl ribonucleotide binding