Mean activities

Top 10 and bottom 10 mean activities.

 Mean activities

Mean activities sorted by motif Z-value.

 Mean activities

Sorted mean activities for every motif.
Motif nameMean activityZ-ValueAssociated genesLogo
CREB1.p2 0.229 1.999 CREB1
XBP1.p3 0.228 0.940 XBP1
PRDM1.p3 0.211 0.704 PRDM1 (PRDI-BF1)
RXRG_dimer.p3 0.197 0.661 NR1H2 (NER, NER-I, RIP15, LXR-b)
RXRA (NR2B1)
PPARG (PPARG1, PPARG2, NR1C3, PPARgamma)
PPARA (hPPAR, NR1C1)
RXRB (NR2B2, H-2RIIBP, RCoR-1)
RXRG (NR2B3)
IRF1,2,7.p3 0.193 1.280 IRF1 (MAR, IRF-1)
IRF2 (IRF-2, DKFZp686F0244)
IRF7 (IRF7A, IRF-7H)
STAT5{A,B}.p2 0.183 0.684 STAT5B
STAT5A (MGF)
FOS_FOS{B,L1}_JUN{B,D}.p2 0.179 1.209 FOS (c-fos, AP-1)
JUNB
FOSL1 (fra-1)
JUND (AP-1)
FOSB (G0S3, GOSB, GOS3, AP-1, MGC42291, DKFZp686C0818)
ZNF143.p2 0.175 2.856 ZNF143 (SBF, pHZ-1, STAF)
FOX{D1,D2}.p2 0.171 1.080 FOXD2 (FREAC9)
FOXD1 (FREAC4)
NRF1.p2 0.169 4.004 NRF1 (EWG, ALPHA-PAL)
ELK1,4_GABP{A,B1}.p3 0.167 3.041 GABPA (E4TF1A, NFT2, NRF2, E4TF1-60, NRF2A)
GABPB1 (E4TF1-47, GABPB)
ELK4 (SAP1)
ELK1
E2F1..5.p2 0.160 1.477 E2F4 (E2F-4)
E2F5
E2F2 (E2F-2)
E2F1 (RBP3)
E2F3
ATF5_CREB3.p2 0.159 1.804 ATF5
CREB3 (LZIP, Luman)
NFIL3.p2 0.153 0.494 NFIL3 (E4BP4, NFIL3A, NF-IL3A)
EHF.p2 0.149 2.089 EHF
PAX2.p2 0.127 1.577 PAX2
NFY{A,B,C}.p2 0.120 1.934 NFYC (CBF-C)
NFYB (CBF-A, HAP3)
NFYA (HAP2, CBF-B)
ATF4.p2 0.115 0.914 ATF4 (TAXREB67, CREB-2)
FOXN1.p2 0.111 0.790 FOXN1 (FKHL20)
SREBF1,2.p2 0.100 0.640 SREBF1 (SREBP1, bHLHd1)
SREBF2 (SREBP2, bHLHd2)
MYB.p2 0.099 1.159 MYB (c-myb)
YY1.p2 0.094 2.855 YY1 (NF-E1, DELTA, UCRBP, YIN-YANG-1, INO80S)
CTCF.p2 0.092 0.660 CTCF
SOX{8,9,10}.p2 0.092 0.780 SOX9 (SRA1)
SOX8
SOX10 (DOM, WS4, WS2E)
POU2F1..3.p2 0.085 0.443 POU2F2 (OCT2)
POU2F1 (OCT1)
POU2F3 (OCT11, PLA-1, Skn-1a, Epoc-1)
TEAD1.p2 0.082 0.457 TEAD1 (TEF-1)
TEAD2 (ETF, TEF4, TEF-4, TEAD-2)
TEAD3 (TEF5, TEAD5, TEF-5, DTEF-1, ETFR-1, TEAD-3)
TEAD4 (TEF3, RTEF1, TEF-3, EFTR-2, TEFR-1, TCF13L1, hRTEF-1B)
PBX1.p2 0.082 0.377 PBX1
ELF1,2,4.p2 0.082 1.802 ELF2 (EU32, NERF, NERF-2, NERF-1A, NERF-1B)
ELF1
ELF4 (MEF, ELFR)
GFI1.p2 0.080 0.974 GFI1
HBP1_HMGB_SSRP1_UBTF.p2 0.077 0.746 HMGB2
HMGB3 (HMG2A, MGC90319)
SSRP1 (FACT80)
UBTF (UBF, NOR-90)
HBP1
NFKB1_REL_RELA.p2 0.069 0.711 RELA (p65)
REL (I-Rel)
NFKB1 (KBF1, p105)
BACH2.p2 0.065 0.273 BACH2
TLX2.p2 0.052 0.485 TLX2 (Enx, Tlx2, NCX)
NFE2L2.p2 0.051 0.222 NFE2L2 (NRF2)
bHLH_family.p2 0.050 0.727 ARNTL (MOP3, JAP3, BMAL1, PASD3, bHLHe5)
MITF (WS2A, MI, bHLHe32)
MXI1 (MXD2, MAD2, MXI, bHLHc11)
TFE3 (TFEA, bHLHe33)
CLOCK (KIAA0334, KAT13D, bHLHe8)
OLIG2 (RACK17, OLIGO2, bHLHe19)
MXD4 (MAD4, MSTP149, MST149, bHLHc12)
HEY2 (bHLHb32)
HEY1 (HESR-1, CHF2, HESR1, HRT-1, CHF-2, HERP2, BHLHb31)
HEYL (bHLHb33)
MLXIPL (WS-bHLH, MIO, CHREBP, MONDOB)
HES6 (bHLHc23)
MXD3 (MAD3, bHLHc13)
ARNTL2 (BMAL2, MOP9, CLIF, PASD9, bHLHe6)
ID1 (dJ857M17.1.2, bHLHb24)
MNT (ROX, MXD6, MAD6, bHLHd3)
OLIG1 (BHLHB6, bHLHe21)
NPAS2 (MOP4, PASD4, bHLHe9)
HES1.p2 0.048 0.788 HES1 (FLJ20408, HES-1, Hes1, bHLHb39)
MAFB.p2 0.044 1.037 MAFB
RBPJ.p2 0.043 0.285 RBPJ (SUH, IGKJRB, RBPJK, KBF2, RBP-J, CBF1)
GZF1.p2 0.043 0.045 GZF1 (dJ322G13.2, ZBTB23)
HLF.p2 0.042 0.168 HLF (MGC33822)
AHR_ARNT_ARNT2.p2 0.041 0.777 ARNT (HIF-1beta, bHLHe2)
AHR
ARNT2 (KIAA0307, bHLHe1)
NKX3-2.p2 0.037 0.448 NKX3-2 (NKX3B, NKX3.2)
BPTF.p2 0.033 0.782 BPTF (FAC1, NURF301)
HIF1A.p2 0.031 0.361 HIF1A (MOP1, HIF-1alpha, PASD8, HIF1)
SP1.p2 0.031 1.596 SP1
ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2 0.027 0.226 ARNT (HIF-1beta, bHLHe2)
MAX (bHLHd4)
MYC (c-Myc, bHLHe39)
USF1 (UEF, MLTFI, bHLHb11)
BHLHB2 (DEC1, bHLHe40)
ARNT2 (KIAA0307, bHLHe1)
NKX2-2,8.p2 0.024 0.133 NKX2-2 (NKX2.2)
NKX2-8 (NKX2.8, Nkx2-9)
IKZF1.p2 0.024 0.190 IKZF1 (hIk-1, LyF-1, Hs.54452, IKAROS)
KLF4.p3 0.023 1.017 KLF4 (EZF, GKLF)
FOXD3.p2 0.022 0.317 FOXD3 (Genesis, HFH2)
SPI1.p2 0.022 0.611 SPI1 (PU.1, SPI-A, OF, SFPI1, SPI-1)
SPIB.p2 0.021 0.478 SPIB (SPI-B)
STAT2,4,6.p2 0.020 0.262 STAT2 (STAT113)
STAT4
STAT6 (D12S1644, IL-4-STAT)
FOXO1,3,4.p2 0.020 0.150 FOXO1 (FKH1)
FOXO4 (AFX1)
FOXO3 (AF6q21, FOXO2)
TFDP1.p2 0.020 1.120 TFDP1 (Dp-1, DRTF1, DP1)
NFIX.p2 0.019 0.107 NFIX (NF1A)
ESRRA.p2 0.017 0.106 ESRRA (ERR1, ERRalpha, NR3B1, ERRa)
NFE2.p2 0.014 0.068 NFE2 (NF-E2)
RFX1..5_RFXANK_RFXAP.p2 0.014 0.137 RFX1 (EF-C)
RFXAP
RFX5
RFXANK (BLS, RFX-B, ANKRA1, F14150_1, MGC138628)
RFX4
RFX3
RFX2 (FLJ14226)
PAX5.p2 0.012 0.468 PAX5 (BSAP)
TP53.p2 0.009 0.044 TP53 (p53, LFS1)
ZNF384.p2 0.006 0.074 ZNF384 (CAGH1A, CIZ, NMP4, NP)
EP300.p2 0.006 0.085 EP300 (p300, KAT3B)
PRRX1,2.p2 0.006 0.118 PRRX2 (PRX2, PMX2)
PRRX1 (PHOX1)
SPZ1.p2 0.005 0.098 SPZ1 (NYD-TSP1, FLJ25709)
TFAP2{A,C}.p2 0.004 0.287 TFAP2C (AP2-GAMMA, ERF1, TFAP2G, hAP-2g)
TFAP2A (AP-2)
LEF1_TCF7_TCF7L1,2.p2 0.003 0.022 TCF7 (TCF-1)
TCF7L2 (TCF-4)
LEF1 (TCF1ALPHA)
TCF7L1
NHLH1,2.p2 0.003 0.070 NHLH1 (NSCL, NSCL1, bHLHa35)
NHLH2 (NSCL2, bHLHa34)
TFAP4.p2 0.003 0.038 TFAP4 (AP-4)
ZIC1..3.p2 0.003 0.028 ZIC1 (ZIC, ZNF201)
ZIC2 (HPE5)
ZIC3 (HTX, ZNF203)
GTF2I.p2 -0.000 -0.011 GTF2I (TFII-I, BAP-135, SPIN, BTKAP1, DIWS, IB291)
MEF2{A,B,C,D}.p2 -0.002 -0.013 MEF2A (RSRFC4, RSRFC9)
MEF2C
MEF2D
MEF2BNB-MEF2B (MEF2B, LOC729991-MEF2B)
MEF2B (RSRFR2, FLJ32648)
MYBL2.p2 -0.002 -0.009 MYBL2 (BMYB, B-MYB)
DMAP1_NCOR{1,2}_SMARC.p2 -0.002 -0.013 SMARCA1 (SNF2LB, NURF140, ISWI, SWI)
SMARCC2 (BAF170, Rsc8, CRACC2)
SMARCA5 (hSNF2H, hISWI, ISWI)
NCOR1 (N-CoR, hCIT529I10, TRAC1, hN-CoR, KIAA1047, MGC104216)
NCOR2 (SMRT, SMRTE, TRAC-1, CTG26, TNRC14)
DMAP1 (DNMAP1, FLJ11543, KIAA1425, DNMTAP1, EAF2, SWC4)
ZBTB6.p2 -0.003 -0.047 ZBTB6 (ZID)
EWSR1-FLI1.p2 -0.004 -0.018 FLI1 (EWSR2, SIC-1)
EWSR1 (EWS, K984G1.4)
TFAP2B.p2 -0.004 -0.200 TFAP2B (AP2-B)
MZF1.p2 -0.005 -0.198 MZF1 (MZF1B, ZSCAN6, MZF-1, Zfp98)
NKX6-1,2.p2 -0.005 -0.026 NKX6-1 (Nkx6.1)
NKX6-2 (NKX6B, GTX, NKX6.1)
FEV.p2 -0.006 -0.107 FEV (PET-1, HSRNAFEV)
SRY.p2 -0.006 -0.062 SRY (TDF)
FOX{I1,J2}.p2 -0.007 -0.079 FOXI1 (FREAC6)
FOXJ2 (FHX)
PATZ1.p2 -0.007 -0.322 PATZ1 (MAZR, dJ400N23, ZBTB19, ZSG, RIAZ, PATZ)
ATF6.p2 -0.010 -0.083 ATF6 (ATF6A)
EGR1..3.p2 -0.011 -0.298 EGR3 (PILOT)
EGR1 (TIS8, G0S30, NGFI-A, KROX-24, ZIF-268, AT225, ZNF225)
EGR2
ZNF148.p2 -0.013 -0.272 ZNF148 (BERF-1, ZBP-89, BFCOL1, HT-BETA, ZFP148, pHZ-52)
SOX17.p2 -0.013 -0.138 SOX17
NANOG.p2 -0.015 -0.060 NANOG (FLJ12581, FLJ40451)
JUN.p2 -0.015 -0.155 JUN (c-Jun, AP-1)
JUND (AP-1)
JUNB
ESR1.p2 -0.015 -0.141 ESR1 (NR3A1, Era)
ZFP161.p2 -0.016 -0.436 ZFP161 (ZNF478, ZBTB14)
HOX{A6,A7,B6,B7}.p2 -0.017 -0.457 HOXB6
HOXA7
HOXB7
HOXA6
IKZF2.p2 -0.017 -0.185 IKZF2 (Helios)
RXR{A,B,G}.p2 -0.018 -0.235 RXRA (NR2B1)
RXRB (NR2B2, H-2RIIBP, RCoR-1)
RXRG (NR2B3)
CDX1,2,4.p2 -0.019 -0.195 CDX1
CDX2
CDX4
TCF4_dimer.p2 -0.019 -0.392 TCF4 (E2-2, ITF2, PTHS, SEF2, SEF2-1, SEF2-1A, SEF2-1B, bHLHb19, MGC149723, MGC149724)
STAT1,3.p3 -0.020 -0.054 STAT1 (STAT91, ISGF-3)
STAT3 (APRF)
MAZ.p2 -0.020 -0.941 MAZ (ZF87, Pur-1, Zif87, ZNF801)
PDX1.p2 -0.022 -0.035 PDX1 (IDX-1, STF-1, PDX-1, MODY4)
HMX1.p2 -0.023 -0.207 HMX1 (H6, NKX5-3)
NFATC1..3.p2 -0.023 -0.243 NFATC3 (NFAT4, NFATX)
NFATC2 (NF-ATP, NFATp, NFAT1)
NFATC1 (NF-ATC, NFATc, NFAT2)
CUX2.p2 -0.024 -0.044 CUX2 (KIAA0293, CDP2)
NKX2-3_NKX2-5.p2 -0.026 -0.150 NKX2-5 (CSX1, NKX2.5, NKX4-1)
NKX2-3 (NKX2.3, CSX3, NKX4-3)
SRF.p3 -0.028 -0.097 SRF (MCM1)
RXRA_VDR{dimer}.p2 -0.030 -0.087 VDR (NR1I1)
CRX.p2 -0.030 -0.205 CRX (CRD, LCA7, OTX3)
ADNP_IRX_SIX_ZHX.p2 -0.034 -0.306 SIX5
ZHX1
IRX4
ADNP (KIAA0784, ADNP1)
ZHX3 (KIAA0395)
ZHX2 (KIAA0854)
IRX5 (IRX-2a)
SIX2
ZBTB16.p2 -0.034 -0.322 ZBTB16 (PLZF)
FOXQ1.p2 -0.035 -0.224 FOXQ1 (HFH1)
MTF1.p2 -0.036 -0.875 MTF1
SOX2.p2 -0.036 -0.355 SOX2
PAX4.p2 -0.037 -0.200 PAX4
HIC1.p2 -0.043 -1.487 HIC1 (ZBTB29)
LMO2.p2 -0.047 -0.641 LMO2 (TTG2, RHOM2, RBTN2)
ZEB1.p2 -0.048 -0.752 ZEB1 (BZP, ZEB, AREB6, NIL-2-A, Zfhep, Zfhx1a)
NR1H4.p2 -0.051 -0.304 NR1H4 (FXR, RIP14, HRR1, HRR-1)
TBX4,5.p2 -0.052 -0.464 TBX5
TBX4
FOSL2.p2 -0.055 -0.288 FOSL2 (FRA2, FLJ23306)
HMGA1,2.p2 -0.056 -0.721 HMGA1
HMGA2 (BABL, LIPO)
ETS1,2.p2 -0.057 -0.819 ETS2
ETS1 (FLJ10768, ETS-1)
NR5A1,2.p2 -0.057 -0.659 NR5A1 (FTZ1, SF-1, ELP, AD4BP)
NR5A2 (FTZ-F1beta, hB1F, LRH-1, FTZ-F1, hB1F-2, B1F2)
FOX{F1,F2,J1}.p2 -0.057 -0.275 FOXF2 (FREAC2)
FOXJ1 (HFH-4, HFH4)
FOXF1 (FREAC1)
TBP.p2 -0.057 -0.312 TBP (TFIID)
GTF2A1,2.p2 -0.058 -0.436 GTF2A1 (TFIIA)
GTF2A2 (TFIIA, HsT18745)
POU5F1.p2 -0.058 -0.576 POU5F1 (OCT3, Oct4, MGC22487)
EBF1.p2 -0.059 -0.680 EBF1 (OLF1)
GLI1..3.p2 -0.060 -0.549 GLI1
GLI2 (THP2, HPE9, THP1)
GLI3 (PAP-A, PAPA, PAPA1, PAPB, ACLS, PPDIV)
SOX5.p2 -0.063 -0.475 SOX5 (L-SOX5, MGC35153)
ATF2.p2 -0.064 -0.450 ATF2 (TREB7, CRE-BP1, HB16)
MYFfamily.p2 -0.064 -1.647 MYOD1 (PUM, MYOD, bHLHc1)
MYF6 (MRF4, bHLHc4)
MYF5 (bHLHc2)
MYOG (bHLHc3)
TFEB.p2 -0.065 -0.584 TFEB
TFCP2.p2 -0.065 -1.223 TFCP2 (CP2, LSF, LBP-1C, TFCP2C)
LHX3,4.p2 -0.066 -0.359 LHX3
LHX4 (Gsh4)
PITX1..3.p2 -0.068 -1.020 PITX2 (IGDS, RS, Brx1, Otlx2, ARP1)
PITX3
PITX1 (PTX1, POTX)
NFE2L1.p2 -0.069 -1.287 NFE2L1 (NRF1, LCR-F1, FLJ00380, TCF11)
HSF1,2.p2 -0.069 -0.617 HSF1 (HSTF1)
HSF2
POU3F1..4.p2 -0.071 -0.260 POU3F1 (OCT6, SCIP)
POU3F3 (BRN1, OTF8)
POU3F2 (POUF3, BRN2, OCT7)
POU3F4 (BRN4, OTF9)
AIRE.p2 -0.072 -0.239 AIRE (PGA1, APS1)
HOX{A4,D4}.p2 -0.075 -0.593 HOXA4
HOXD4
PPARG.p2 -0.075 -0.191 PPARG (PPARG1, PPARG2, NR1C3, PPARgamma)
CEBPA,B_DDIT3.p2 -0.075 -0.225 DDIT3 (CHOP10, GADD153, CHOP)
CEBPA (C/EBP-alpha)
CEBPB (LAP, CRP2, NFIL6, IL6DBP)
SNAI1..3.p2 -0.077 -1.573 SNAI2 (SLUGH1)
SNAI1 (SNA, SLUGH2, SNAH)
SNAI3 (SMUC, Zfp293)
KLF12.p2 -0.078 -1.556 KLF12 (AP-2rep, HSPC122, AP2REP)
GATA1..3.p2 -0.080 -1.663 GATA1 (ERYF1, NFE1)
GATA2 (NFE1B)
GATA3 (HDR)
RREB1.p2 -0.080 -2.303 RREB1 (HNT)
VSX1,2.p2 -0.080 -0.130 VSX2 (RET1)
VSX1 (PPD)
DBP.p2 -0.082 -0.801 DBP (DABP)
NR6A1.p2 -0.090 -0.182 NR6A1 (GCNF1, RTR)
HNF4A_NR2F1,2.p2 -0.091 -1.114 NR2F1 (EAR-3, COUP-TFI, TCFCOUP1, SVP44)
NR2F2 (COUP-TFII, COUPTFB, SVP40)
HNF4A (NR2A1, HNF4)
FOXA2.p3 -0.091 -0.536 FOXA2
MYOD1.p2 -0.093 -1.217 MYOD1 (PUM, MYOD, bHLHc1)
FOXL1.p2 -0.095 -0.747 FOXL1 (FREAC7, FKH6)
CDC5L.p2 -0.096 -0.427 CDC5L (PCDC5RP, hCDC5, CEF1)
SMAD1..7,9.p2 -0.098 -0.946 SMAD5 (Dwfc, JV5-1)
SMAD1 (MADR1, JV4-1)
SMAD3 (JV15-2, HsT17436)
SMAD4 (DPC4)
SMAD2 (MADR2, JV18-1)
SMAD6 (HsT17432)
SMAD7
SMAD9
ZNF423.p2 -0.102 -0.766 ZNF423 (KIAA0760, OAZ, Roaz, Ebfaz, Zfp104)
ONECUT1,2.p2 -0.102 -0.550 ONECUT2 (OC-2)
ONECUT1 (HNF-6)
NKX3-1.p2 -0.107 -0.504 NKX3-1 (NKX3.1, BAPX2)
TGIF1.p2 -0.110 -0.806 TGIF1
GFI1B.p2 -0.116 -0.428 GFI1B
TLX1..3_NFIC{dimer}.p2 -0.128 -0.757 TLX1
TLX3 (RNX)
ALX1.p2 -0.132 -0.642 ALX1
EOMES.p2 -0.135 -0.645 EOMES (TBR2)
RUNX1..3.p2 -0.138 -1.158 RUNX1 (PEBP2A2, AMLCR1)
RUNX3 (AML2, PEBP2A3)
RUNX2 (AML3, PEBP2A1, PEBP2aA1)
ZNF238.p2 -0.140 -0.642 ZNF238 (C2H2-171, TAZ-1, RP58, ZBTB18)
ARID5B.p2 -0.150 -0.436 ARID5B (FLJ21150, MRF2)
HNF1A.p2 -0.156 -0.567 HNF1A (HNF1, LFB1)
NANOG{mouse}.p2 -0.159 -0.614 NANOG (FLJ12581, FLJ40451)
T.p2 -0.165 -0.386 T
POU5F1_SOX2{dimer}.p2 -0.174 -0.739 POU5F1 (OCT3, Oct4, MGC22487)
SOX2
NR3C1.p2 -0.177 -0.614 NR3C1 (GR)
EVI1.p2 -0.188 -1.289 EVI1 (MDS1-EVI1, PRDM3)
POU1F1.p2 -0.191 -0.961 POU1F1 (GHF-1)
TAL1_TCF{3,4,12}.p2 -0.198 -0.504 TCF3 (E2A, ITF1, MGC129647, MGC129648, bHLHb21)
TCF4 (SEF2-1B, ITF2, bHLHb19)
TAL1 (SCL, bHLHa17)
TCF12 (HEB, HTF4, HsT17266, bHLHb20)
POU6F1.p2 -0.199 -0.672 POU6F1 (BRN5, MPOU, TCFB1)
FOX{C1,C2}.p2 -0.204 -0.624 FOXC1 (FREAC3, ARA, IGDA, IHG1)
FOXC2 (MFH-1)
MSX1,2.p2 -0.207 -0.428 MSX1 (HYD1, OFC5)
MSX2 (CRS2, FPP, HOX8, MSH, PFM)
PAX8.p2 -0.218 -0.120 PAX8
GATA6.p2 -0.227 -1.101 GATA6
RORA.p2 -0.228 -0.506 RORA (RZRA, ROR1, ROR2, ROR3, NR1F1)
HOX{A5,B5}.p2 -0.234 -1.138 HOXB5
HOXA5
HOXA9_MEIS1.p2 -0.257 -0.583 MEIS1
HOXA9
HAND1,2.p2 -0.287 -1.293 HAND1 (eHand, Thing1, Hxt, bHLHa27)
HAND2 (dHand, Thing2, Hed, bHLHa26)
NKX2-1,4.p2 -0.300 -0.727 NKX2-1 (TTF-1)
NKX2-4 (NKX2.4)
FOXP3.p2 -0.305 -0.825 FOXP3 (JM2, XPID, AIID, PIDX, DIETER, SCURFIN)
PAX6.p2 -0.329 -0.476 PAX6 (D11S812E, AN, WAGR)
EN1,2.p2 -0.336 -1.592 EN1
EN2
AR.p2 -0.343 -0.549 AR (AIS, NR3C4, SMAX1, HUMARA)
REST.p3 -0.714 -2.209 REST (NRSF, XBR)
PAX3,7.p2 -1.375 -0.680 PAX7 (Hup1)
PAX3 (HUP2)