Motif ID: ZNF238.p2

Z-value: 2.518


Transcription factors associated with ZNF238.p2:

Gene SymbolEntrez IDGene Name
ZNF238 10472 zinc finger protein 238



Activity profile for motif ZNF238.p2.

activity profile for motif ZNF238.p2


Sorted Z-values histogram for motif ZNF238.p2

Sorted Z-values for motif ZNF238.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF238.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_122571046 7.622 CLMP
CXADR-like membrane protein
chr16_+_54070302 5.378 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr20_+_19903778 4.417 RIN2
Ras and Rab interactor 2
chr2_-_162808123 3.907 NM_004460
FAP
fibroblast activation protein, alpha
chr7_+_90063543 3.144 CDK14
cyclin-dependent kinase 14
chr12_+_13240987 3.096 EMP1
epithelial membrane protein 1
chr12_+_13240983 3.012 EMP1
epithelial membrane protein 1
chr11_-_68537243 2.948 NM_001098515
NM_145015
MRGPRF

MAS-related GPR, member F

chrX_-_19598912 2.860 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr19_-_48866111 2.843 NM_001005376
NM_001005377
NM_002659
PLAUR


plasminogen activator, urokinase receptor


chr10_+_99463446 2.821 NM_031484
MARVELD1
MARVEL domain containing 1
chr10_+_99463468 2.716 MARVELD1
MARVEL domain containing 1
chr2_+_201182187 2.627 AOX1
aldehyde oxidase 1
chr12_-_102968044 2.555 NM_031302
GLT8D2
glycosyltransferase 8 domain containing 2
chr12_-_105056577 2.523 NUAK1
NUAK family, SNF1-like kinase, 1
chr12_-_102967828 2.460 GLT8D2
glycosyltransferase 8 domain containing 2
chr16_-_30983909 2.439 NM_001172669
NM_001172670
ZNF668

zinc finger protein 668

chr7_-_135083906 2.408 NM_205855
FAM180A
family with sequence similarity 180, member A
chr11_-_56846246 2.381 TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr11_-_33678861 2.112 NM_001166692
C11orf91
chromosome 11 open reading frame 91
chr4_+_14985272 2.089 NM_001135171
C1QTNF7
C1q and tumor necrosis factor related protein 7
chr17_+_58058774 2.013 MRC2
mannose receptor, C type 2
chr10_-_95231933 1.982 NM_013451
NM_133337
MYOF

myoferlin

chr2_+_151922350 1.974 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr17_+_45488330 1.932 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr16_-_65742323 1.910 NM_033309
B3GNT9
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr17_+_7732759 1.904 NM_001005273
NM_005852
CHD3

chromodomain helicase DNA binding protein 3

chr12_+_26239755 1.895 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr3_-_11585264 1.878 NM_001128221
VGLL4
vestigial like 4 (Drosophila)
chr12_-_29827952 1.866 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr1_-_17179694 1.836 NM_001135248
NM_002403
MFAP2

microfibrillar-associated protein 2

chr15_+_65205107 1.824 NM_001145102
SMAD3
SMAD family member 3
chr4_+_47181987 1.824 NM_020453
ATP10D
ATPase, class V, type 10D
chr8_-_17599438 1.812 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr5_+_49998677 1.811 PARP8
poly (ADP-ribose) polymerase family, member 8
chr17_+_45488356 1.793 ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr4_+_114433551 1.692 ANK2
ankyrin 2, neuronal
chr15_+_78775008 1.630 FAM108C1
family with sequence similarity 108, member C1
chr1_-_151784889 1.621 NM_002961
NM_019554
S100A4

S100 calcium binding protein A4

chr19_-_11166186 1.596 NM_015493
KANK2
KN motif and ankyrin repeat domains 2
chr2_+_189547377 1.480 COL3A1
collagen, type III, alpha 1
chr19_-_10202947 1.452 NM_004230
S1PR2
sphingosine-1-phosphate receptor 2
chr2_-_158439868 1.436 NM_001105
ACVR1
activin A receptor, type I
chr3_-_161650219 1.412 TRIM59
tripartite motif containing 59
chr12_-_62902279 1.407 NM_152440
C12orf66
chromosome 12 open reading frame 66
chr2_+_189547323 1.380 NM_000090
COL3A1
collagen, type III, alpha 1
chr1_-_146398501 1.377 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chr4_-_152368492 1.367 SH3D19
SH3 domain containing 19
chr2_+_189547358 1.362 COL3A1
collagen, type III, alpha 1
chr22_-_43271843 1.340 LDOC1L
leucine zipper, down-regulated in cancer 1-like
chr2_+_33213111 1.300 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr1_+_159943385 1.284 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr2_-_101457596 1.279 NM_001145664
RFX8
regulatory factor X, 8
chr21_+_29439768 1.250 C21orf7
chromosome 21 open reading frame 7
chr1_-_16217025 1.245 HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr6_+_39868770 1.232 NM_015345
DAAM2
dishevelled associated activator of morphogenesis 2
chr12_-_46585032 1.231 NM_000376
NM_001017535
VDR

vitamin D (1,25- dihydroxyvitamin D3) receptor

chr6_-_150253729 1.224 NM_139165
RAET1E
retinoic acid early transcript 1E
chr5_+_49998528 1.208 NM_001178056
NM_024615
PARP8

poly (ADP-ribose) polymerase family, member 8

chr8_+_1759502 1.176 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr3_-_112796855 1.170 NM_024508
ZBED2
zinc finger, BED-type containing 2
chr5_-_64813459 1.155 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr9_-_90456824 1.116 NM_001100111
LOC286238
hypothetical protein LOC286238
chr1_+_53300410 1.113 NM_153703
PODN
podocan
chr3_-_191321601 1.101 NM_018192
LEPREL1
leprecan-like 1
chr15_+_29406335 1.093 NM_015995
KLF13
Kruppel-like factor 13
chr5_-_178704934 1.088 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr12_+_26239535 1.080 NM_001135823
SSPN
sarcospan (Kras oncogene-associated gene)
chr5_+_172000793 1.079 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chrX_+_99786044 1.067 SRPX2
sushi-repeat containing protein, X-linked 2
chr5_-_178705036 1.063 NM_014244
NM_021599
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr11_-_11600118 1.050 NM_198516
GALNTL4
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 4
chr16_+_65868913 1.046 NM_015432
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr14_-_60818263 1.033 NM_001017970
TMEM30B
transmembrane protein 30B
chr17_+_36515166 0.986 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr12_-_6313219 0.973 TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr11_+_113815317 0.964 NM_015523
REXO2
REX2, RNA exonuclease 2 homolog (S. cerevisiae)
chr10_-_22332368 0.909 DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chrX_+_99785818 0.905 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr17_+_58058783 0.899 MRC2
mannose receptor, C type 2
chr17_-_24491521 0.890 MYO18A
myosin XVIIIA
chr1_-_154913712 0.882 NM_006617
NES
nestin
chr1_-_143232275 0.874 LOC728855
hypothetical LOC728855
chr9_+_130722994 0.871 NM_001100876
NM_174933
PHYHD1

phytanoyl-CoA dioxygenase domain containing 1

chr4_-_122063118 0.866 NM_018699
PRDM5
PR domain containing 5
chr3_-_64186151 0.852 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr22_+_36401558 0.842 NM_002305
LGALS1
lectin, galactoside-binding, soluble, 1
chr18_-_44723116 0.839 NM_001190823
SMAD7
SMAD family member 7
chr1_-_215329569 0.833 NM_206594
NM_206595
ESRRG

estrogen-related receptor gamma

chr2_+_12774264 0.822 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr9_+_71848555 0.818 MAMDC2
MAM domain containing 2
chr3_+_101694098 0.816 NM_018004
TMEM45A
transmembrane protein 45A
chr12_+_111047742 0.815 TRAFD1
TRAF-type zinc finger domain containing 1
chr10_-_22332600 0.804 DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr1_-_152185764 0.797 NM_014856
DENND4B
DENN/MADD domain containing 4B
chr12_-_48508411 0.777 NM_001037806
NCKAP5L
NCK-associated protein 5-like
chr16_-_63713466 0.777 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr12_+_111047676 0.744 NM_001143906
NM_006700
TRAFD1

TRAF-type zinc finger domain containing 1

chr11_+_7463175 0.741 NM_198474
OLFML1
olfactomedin-like 1
chrX_-_10548458 0.730 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr7_+_143646150 0.726 NM_001005287
NM_001001802
OR2A1
OR2A42
olfactory receptor, family 2, subfamily A, member 1
olfactory receptor, family 2, subfamily A, member 42
chr6_+_39868126 0.725 DAAM2
dishevelled associated activator of morphogenesis 2
chr17_-_45629401 0.723


chr1_-_153444304 0.716 NM_007112
THBS3
thrombospondin 3
chr1_-_142535878 0.711 LOC100286793
FLJ39739
hypothetical LOC100286793
hypothetical FLJ39739
chrX_-_101658297 0.709 NM_021992
TMSB15A
TMSB15B
thymosin beta 15a
thymosin beta 15B
chr3_-_115585178 0.709 NM_001164342
ZBTB20
zinc finger and BTB domain containing 20
chr20_-_48686832 0.706 NM_080829
FAM65C
family with sequence similarity 65, member C
chr6_+_39868116 0.693


chr7_+_116099648 0.691 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr12_+_62524778 0.687 NM_020762
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr1_-_143232344 0.685 LOC728855
hypothetical LOC728855
chr13_+_51933228 0.682 CKAP2
cytoskeleton associated protein 2
chr12_+_2032649 0.679 NM_000719
NM_001129827
NM_001129829
NM_001129830
NM_001129831
NM_001129832
NM_001129833
NM_001129834
NM_001129835
NM_001129836
NM_001129837
NM_001129838
NM_001129839
NM_001129840
NM_001129841
NM_001129842
NM_001129843
NM_001129844
NM_001129846
NM_001167623
NM_001167624
NM_001167625
NM_199460
CACNA1C






















calcium channel, voltage-dependent, L type, alpha 1C subunit






















chr1_-_36387653 0.678 NM_014408
TRAPPC3
trafficking protein particle complex 3
chr21_+_46226072 0.672 NM_001848
COL6A1
collagen, type VI, alpha 1
chr17_+_74531820 0.669 NM_030968
NM_198594
C1QTNF1

C1q and tumor necrosis factor related protein 1

chr16_-_63713485 0.668 CDH11
cadherin 11, type 2, OB-cadherin (osteoblast)
chr3_+_185377430 0.664 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr3_+_30623376 0.664 TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr17_-_36587965 0.659 NM_033062
KRTAP4-2
keratin associated protein 4-2
chr9_+_71848316 0.659 NM_153267
MAMDC2
MAM domain containing 2
chr10_+_44726635 0.656 NM_001123376
TMEM72
transmembrane protein 72
chr1_+_31655607 0.647 NM_001199037
SERINC2
serine incorporator 2
chr1_+_64709063 0.644 NM_020925
CACHD1
cache domain containing 1
chr19_+_44595589 0.638 NM_022835
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr1_-_205272619 0.636 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr3_+_101694244 0.634 TMEM45A
transmembrane protein 45A
chr9_+_123369219 0.621 NM_032552
DAB2IP
DAB2 interacting protein
chr7_+_4980144 0.617 RNF216L
ring finger protein 216-like
chr9_+_115396020 0.608 NM_144489
RGS3
regulator of G-protein signaling 3
chr17_-_51164443 0.604 NM_001099640
TMEM100
transmembrane protein 100
chr20_+_17498507 0.600 NM_001011546
NM_006870
DSTN

destrin (actin depolymerizing factor)

chr11_+_74950766 0.599 NM_001235
SERPINH1
serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr1_-_33585848 0.596


chr18_+_7557313 0.595 NM_001105244
NM_002845
PTPRM

protein tyrosine phosphatase, receptor type, M

chr19_+_11510578 0.586 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr1_-_19155360 0.575 NM_001136265
IFFO2
intermediate filament family orphan 2
chr5_-_142764168 0.566 NM_001018076
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr3_+_185377341 0.562 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr12_-_46405477 0.559 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chr19_+_4861339 0.549 NM_013282
UHRF1
ubiquitin-like with PHD and ring finger domains 1
chr3_+_69216747 0.546 NM_006407
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr5_-_142764295 0.543 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr10_-_63698463 0.543 NM_145307
RTKN2
rhotekin 2
chr1_-_143232464 0.541


chr19_-_47155340 0.539 NM_006423
RABAC1
Rab acceptor 1 (prenylated)
chr5_+_140772691 0.534 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr7_+_5609416 0.532 FSCN1
fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
chr12_-_15833383 0.529 EPS8
epidermal growth factor receptor pathway substrate 8
chr1_-_36387458 0.527 TRAPPC3
trafficking protein particle complex 3
chr11_-_40272239 0.523 NM_020929
LRRC4C
leucine rich repeat containing 4C
chr15_-_81743198 0.521 BNC1
basonuclin 1
chr17_+_74531873 0.516 C1QTNF1
C1q and tumor necrosis factor related protein 1
chr17_-_64649608 0.514 NM_080284
ABCA6
ATP-binding cassette, sub-family A (ABC1), member 6
chr6_-_30631481 0.512 GNL1
guanine nucleotide binding protein-like 1
chr1_-_166965034 0.509 NM_001937
DPT
dermatopontin
chr2_+_234302511 0.507 NM_019093
UGT1A3
UDP glucuronosyltransferase 1 family, polypeptide A3
chr10_-_105427898 0.506 SH3PXD2A
SH3 and PX domains 2A
chr1_-_85816520 0.505 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr14_+_104218487 0.505


chr9_+_124590970 0.503 NM_001001923
OR5C1
olfactory receptor, family 5, subfamily C, member 1
chr21_+_45699830 0.503 NM_030582
NM_130444
COL18A1

collagen, type XVIII, alpha 1

chr14_+_95792299 0.499 NM_000710
BDKRB1
bradykinin receptor B1
chr10_-_22332646 0.498 NM_022365
DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr19_+_4861166 0.493 UHRF1
ubiquitin-like with PHD and ring finger domains 1
chr1_+_202308814 0.493 NM_005686
SOX13
SRY (sex determining region Y)-box 13
chr1_+_210848592 0.491 NM_001040619
NM_001674
ATF3

activating transcription factor 3

chr15_-_76890626 0.490 NM_014272
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr15_+_47502666 0.488 NM_002009
FGF7
fibroblast growth factor 7
chrX_-_34585287 0.486 NM_031442
TMEM47
transmembrane protein 47
chr15_+_54998115 0.484 NM_003205
NM_207036
NM_207037
NM_207038
TCF12



transcription factor 12



chr10_-_123347493 0.483 NM_000141
NM_001144917
NM_001144918
NM_001144919
NM_022970
FGFR2




fibroblast growth factor receptor 2




chr5_+_40715799 0.481 PTGER4
prostaglandin E receptor 4 (subtype EP4)
chr11_+_10283171 0.480 NM_001124
ADM
adrenomedullin
chr1_-_199742864 0.469 CSRP1
cysteine and glycine-rich protein 1
chrX_+_149280486 0.469 MAMLD1
mastermind-like domain containing 1
chr12_-_106678910 0.462 PRDM4
PR domain containing 4
chr15_+_54998144 0.461 TCF12
transcription factor 12
chr6_-_10527772 0.461 NM_001042425
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr15_+_54998264 0.461 TCF12
transcription factor 12
chr1_+_184532027 0.459 NM_001127708
NM_001127709
NM_001127710
NM_005807
PRG4



proteoglycan 4



chr1_+_210848763 0.454 ATF3
activating transcription factor 3
chr14_+_93646831 0.450 NM_001130080
NM_005532
IFI27

interferon, alpha-inducible protein 27

chr19_+_18529571 0.447 NM_001171948
NM_001171949
NM_024069
C19orf50


chromosome 19 open reading frame 50


chr10_+_6284845 0.447 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr7_+_120756325 0.441 NM_057168
WNT16
wingless-type MMTV integration site family, member 16
chr11_-_74478405 0.440 NM_001005285
OR2AT4
olfactory receptor, family 2, subfamily AT, member 4
chr5_+_14493905 0.438 TRIO
triple functional domain (PTPRF interacting)
chr11_-_6746763 0.438 NM_001004490
OR2AG2
olfactory receptor, family 2, subfamily AG, member 2
chr1_-_142536082 0.433


chr1_-_199742871 0.432 NM_001193570
NM_004078
CSRP1

cysteine and glycine-rich protein 1

chr14_+_64041257 0.429 ZBTB1
zinc finger and BTB domain containing 1
chr6_-_30766621 0.429 NM_007243
NRM
nurim (nuclear envelope membrane protein)
chr16_+_79829794 0.429 NM_017429
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr22_-_40941254 0.423 NM_005650
NM_181492
TCF20

transcription factor 20 (AR1)

chr3_-_171013145 0.423 NM_001172779
NM_001172780
NM_153353
LRRC34


leucine rich repeat containing 34


chr1_+_210848726 0.423 ATF3
activating transcription factor 3
chr21_-_38210531 0.416 NM_002240
KCNJ6
potassium inwardly-rectifying channel, subfamily J, member 6
chr7_-_124192916 0.416 NM_005302
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
2.86 9.03e-06 GO:0007608 sensory perception of smell
2.56 1.75e-04 GO:0007606 sensory perception of chemical stimulus
1.90 1.87e-02 GO:0007600 sensory perception
1.56 4.76e-02 GO:0003008 system process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
5.16 1.05e-04 GO:0045095 keratin filament
1.35 1.03e-03 GO:0005886 plasma membrane
2.61 1.37e-03 GO:0005578 proteinaceous extracellular matrix
1.33 2.55e-03 GO:0071944 cell periphery
2.37 4.06e-03 GO:0031012 extracellular matrix
1.50 6.43e-03 GO:0005576 extracellular region
2.90 7.78e-03 GO:0045111 intermediate filament cytoskeleton
3.00 1.31e-02 GO:0005882 intermediate filament
3.08 4.45e-02 GO:0043235 receptor complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
3.00 5.90e-07 GO:0004984 olfactory receptor activity
2.10 4.78e-05 GO:0004930 G-protein coupled receptor activity
1.86 5.17e-05 GO:0004888 transmembrane receptor activity
1.69 1.40e-04 GO:0004872 receptor activity
1.58 4.55e-04 GO:0004871 signal transducer activity
1.58 4.55e-04 GO:0060089 molecular transducer activity
5.89 1.82e-02 GO:0003823 antigen binding