Motif ID: GTF2A1,2.p2

Z-value: 1.602


Transcription factors associated with GTF2A1,2.p2:

Gene SymbolEntrez IDGene Name
GTF2A1 2957 general transcription factor IIA, 1, 19/37kDa
GTF2A2 2958 general transcription factor IIA, 2, 12kDa



Activity profile for motif GTF2A1,2.p2.

activity profile for motif GTF2A1,2.p2


Sorted Z-values histogram for motif GTF2A1,2.p2

Sorted Z-values for motif GTF2A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2A1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_48857962 1.608 ADCY7
adenylate cyclase 7
chr17_+_53769659 1.513 LOC100506779
hypothetical LOC100506779
chr11_+_5610060 1.273 NM_130390
TRIM34
tripartite motif containing 34
chr5_-_114965959 1.215 NM_021649
TICAM2
toll-like receptor adaptor molecule 2
chr20_-_34635091 1.184


chr17_+_4795128 1.171 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr20_+_34635362 1.100 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr2_-_65013070 1.073 LOC400958
hypothetical LOC400958
chr19_+_40895669 1.057 NM_014383
ZBTB32
zinc finger and BTB domain containing 32
chr17_+_53769562 1.054 LOC100506779
hypothetical LOC100506779
chr19_+_5082230 1.000 KDM4B
lysine (K)-specific demethylase 4B
chr3_+_123279439 0.988 NM_006889
CD86
CD86 molecule
chrX_+_49718954 0.959 NM_000084
CLCN5
chloride channel 5
chr9_+_130620540 0.921 NM_004435
ENDOG
endonuclease G
chr16_+_631902 0.910 FAM195A
family with sequence similarity 195, member A
chr17_-_37599953 0.897 NM_001142622
NM_001142623
NM_032484
GHDC


GH3 domain containing


chr17_+_42641712 0.892 NM_002476
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr10_+_92970302 0.862 NM_032373
PCGF5
polycomb group ring finger 5
chr1_-_154205675 0.841 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr10_+_70517863 0.822 SRGN
serglycin
chr17_-_35975227 0.819 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr17_-_45633986 0.801 NM_000088
COL1A1
collagen, type I, alpha 1
chr17_-_60988077 0.787 NM_004655
AXIN2
axin 2
chr5_-_149772563 0.782 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr19_+_54160369 0.757 NM_000146
FTL
ferritin, light polypeptide
chr17_-_45633873 0.756 COL1A1
collagen, type I, alpha 1
chr2_+_27154938 0.749 NM_007046
EMILIN1
elastin microfibril interfacer 1
chr19_+_54160399 0.748 FTL
ferritin, light polypeptide
chr2_+_27155197 0.744 EMILIN1
elastin microfibril interfacer 1
chr6_-_33016561 0.737 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr6_-_49712483 0.735 NM_000324
RHAG
Rh-associated glycoprotein
chr15_-_80125403 0.728 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr11_+_65781322 0.719 NM_001134775
KLC2
kinesin light chain 2
chr10_+_70517823 0.714 NM_002727
SRGN
serglycin
chr10_+_92970487 0.714 PCGF5
polycomb group ring finger 5
chr19_+_59820413 0.712 NM_006669
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr21_+_44597911 0.709 NM_003307
TRPM2
transient receptor potential cation channel, subfamily M, member 2
chr3_-_13032130 0.705


chr16_+_631828 0.704 NM_138418
FAM195A
family with sequence similarity 195, member A
chr16_+_29984544 0.693 NM_184041
ALDOA
aldolase A, fructose-bisphosphate
chr16_+_29984591 0.693 ALDOA
aldolase A, fructose-bisphosphate
chr2_-_144994038 0.689 ZEB2
zinc finger E-box binding homeobox 2
chr1_-_205161821 0.688 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr16_+_29984611 0.682 ALDOA
aldolase A, fructose-bisphosphate
chr1_+_35507197 0.681 ZMYM4
zinc finger, MYM-type 4
chr17_+_17147351 0.671 NM_020201
NT5M
5',3'-nucleotidase, mitochondrial
chr12_+_117067214 0.667 PEBP1
phosphatidylethanolamine binding protein 1
chr20_-_43889339 0.665 NM_003279
TNNC2
troponin C type 2 (fast)
chr5_-_149772528 0.664


chr20_-_35013459 0.664 SAMHD1
SAM domain and HD domain 1
chr17_-_44006808 0.662 NM_002146
HOXB3
homeobox B3
chr6_-_46401174 0.657 RCAN2
regulator of calcineurin 2
chr3_+_99733432 0.652 NM_005290
GPR15
G protein-coupled receptor 15
chr10_-_49152918 0.650 NM_001018071
FRMPD2
FERM and PDZ domain containing 2
chr11_-_63750138 0.646 NM_001033678
NM_001160389
NM_001160390
NM_001160392
NM_031472
TRPT1




tRNA phosphotransferase 1




chr1_+_95355415 0.642 NM_152487
TMEM56
transmembrane protein 56
chr11_+_63864263 0.634 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr6_-_46401363 0.633 NM_005822
RCAN2
regulator of calcineurin 2
chr14_-_22358752 0.633 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr22_+_38246509 0.633 NM_001675
NM_182810
ATF4

activating transcription factor 4 (tax-responsive enhancer element B67)

chr11_-_85074848 0.631 NM_152723
CCDC89
coiled-coil domain containing 89
chr1_-_56817823 0.627 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr16_+_29984621 0.616 ALDOA
aldolase A, fructose-bisphosphate
chr6_-_31977747 0.614 NM_181842
ZBTB12
zinc finger and BTB domain containing 12
chr2_+_113709553 0.614 LOC654433
hypothetical LOC654433
chr5_-_149772469 0.608 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr18_-_3001944 0.604 NM_014646
LPIN2
lipin 2
chr19_+_41085221 0.600 NM_001007469
NM_014266
HCST

hematopoietic cell signal transducer

chr17_-_71404611 0.595 NM_173547
TRIM65
tripartite motif containing 65
chr9_-_135232790 0.584 NM_033161
SURF4
surfeit 4
chr2_-_144994349 0.581 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr5_-_95184121 0.580 GLRX
glutaredoxin (thioltransferase)
chr5_+_32621361 0.568 NM_006713
SUB1
SUB1 homolog (S. cerevisiae)
chr7_-_75206152 0.564 HIP1
huntingtin interacting protein 1
chr17_-_60988226 0.561 AXIN2
axin 2
chr22_+_22459143 0.559 NM_001007468
NM_003073
SMARCB1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1

chr19_+_54160468 0.559 FTL
ferritin, light polypeptide
chr1_+_22107137 0.557 RPL21
ribosomal protein L21
chr9_+_135233047 0.556 NM_153710
C9orf96
chromosome 9 open reading frame 96
chr2_+_190710730 0.552 NM_001042521
C2orf88
chromosome 2 open reading frame 88
chr12_-_7136189 0.550 C1R
complement component 1, r subcomponent
chr19_-_1827133 0.542


chr17_-_36456949 0.542 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr12_-_101396459 0.542 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr5_-_95184221 0.532 NM_001118890
NM_002064
GLRX

glutaredoxin (thioltransferase)

chr5_+_156628929 0.531 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr7_-_75206212 0.525 NM_005338
HIP1
huntingtin interacting protein 1
chr22_-_25205376 0.523 NM_152841
HPS4
Hermansky-Pudlak syndrome 4
chr11_-_63749916 0.521 NM_001160393
TRPT1
tRNA phosphotransferase 1
chr11_+_63750296 0.521 NM_001128612
NM_001128613
NM_032344
NUDT22


nudix (nucleoside diphosphate linked moiety X)-type motif 22


chr7_+_73826244 0.517 NM_000265
NCF1
NCF1B
NCF1C
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
neutrophil cytosolic factor 1C pseudogene
chr9_+_135232937 0.515 C9orf96
chromosome 9 open reading frame 96
chr1_-_158883666 0.515 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr1_-_56817717 0.511 PPAP2B
phosphatidic acid phosphatase type 2B
chr19_-_1430198 0.511 NM_152482
C19orf25
chromosome 19 open reading frame 25
chr3_+_46423682 0.506 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr1_+_984935 0.505 LOC100288175
hypothetical LOC100288175
chr20_-_42457717 0.505


chr2_+_171280182 0.498


chr11_+_65781646 0.498 NM_001134776
NM_001134774
NM_022822
KLC2


kinesin light chain 2


chr1_-_20179495 0.496 NM_000300
NM_001161727
NM_001161728
PLA2G2A


phospholipase A2, group IIA (platelets, synovial fluid)


chr1_-_205012348 0.495 NM_000572
IL10
interleukin 10
chr21_-_42608531 0.487 TFF3
trefoil factor 3 (intestinal)
chr8_+_18111894 0.485 NM_000662
NM_001160170
NM_001160171
NM_001160172
NM_001160173
NM_001160175
NM_001160176
NAT1






N-acetyltransferase 1 (arylamine N-acetyltransferase)






chr1_+_35507145 0.482 NM_005095
ZMYM4
zinc finger, MYM-type 4
chr14_-_50367513 0.479 NM_016350
NM_020921
NM_182944
NM_182946
NIN



ninein (GSK3B interacting protein)



chr21_+_25856311 0.478 MIR155HG
MIR155 host gene (non-protein coding)
chr1_-_56817568 0.477 PPAP2B
phosphatidic acid phosphatase type 2B
chr7_+_68701704 0.472 NM_001127231
NM_001127232
NM_015570
AUTS2


autism susceptibility candidate 2


chr9_-_135232734 0.467 SURF4
surfeit 4
chr9_-_70780574 0.467


chr13_+_31503436 0.466 NM_023037
FRY
furry homolog (Drosophila)
chr11_-_64402629 0.464 NM_006795
EHD1
EH-domain containing 1
chr6_-_42821815 0.461 NM_003192
TBCC
tubulin folding cofactor C
chrX_-_70248022 0.457 NM_000206
IL2RG
interleukin 2 receptor, gamma
chrX_-_153290697 0.456 NM_006730
DNASE1L1
deoxyribonuclease I-like 1
chr9_-_139084833 0.456 NM_178448
C9orf140
chromosome 9 open reading frame 140
chr21_-_36836767 0.452 NM_001146078
CLDN14
claudin 14
chr17_-_1335763 0.451 NM_001080950
MYO1C
myosin IC
chr12_+_91620749 0.449 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr19_-_1430116 0.448 C19orf25
chromosome 19 open reading frame 25
chr19_-_1430194 0.446 C19orf25
chromosome 19 open reading frame 25
chr16_+_56259657 0.446 NM_170776
GPR97
G protein-coupled receptor 97
chr19_-_51081147 0.445 NM_015649
IRF2BP1
interferon regulatory factor 2 binding protein 1
chr6_-_42821790 0.445 TBCC
tubulin folding cofactor C
chr11_+_117982422 0.445 NM_015157
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr19_-_56549853 0.444 NM_001014763
ETFB
electron-transfer-flavoprotein, beta polypeptide
chr7_-_72574528 0.442 NM_032408
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr8_-_23233426 0.442 LOXL2
lysyl oxidase-like 2
chrX_-_30505804 0.442 NM_025159
CXorf21
chromosome X open reading frame 21
chr19_+_10083196 0.442 NM_002566
P2RY11
purinergic receptor P2Y, G-protein coupled, 11
chr2_+_108751033 0.441 RANBP2
RAN binding protein 2
chr11_+_116554597 0.437 SIDT2
SID1 transmembrane family, member 2
chr22_-_37598160 0.436 CBX6
chromobox homolog 6
chr2_+_30523586 0.434 NM_182551
NM_001002257
LCLAT1

lysocardiolipin acyltransferase 1

chr6_-_42821800 0.432 TBCC
tubulin folding cofactor C
chr2_-_218516950 0.430 NM_022648
TNS1
tensin 1
chr14_+_23633101 0.429 NM_001018073
NM_004563
PCK2

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

chr7_+_1094248 0.429 NM_001098201
GPER
G protein-coupled estrogen receptor 1
chr11_-_64402501 0.428 EHD1
EH-domain containing 1
chr19_+_1018536 0.428 HMHA1
histocompatibility (minor) HA-1
chr17_-_8711701 0.428 NM_001010855
PIK3R6
phosphoinositide-3-kinase, regulatory subunit 6
chr2_+_176737050 0.425 NM_006898
HOXD3
homeobox D3
chr17_+_7180571 0.425 NM_014716
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr1_+_149520601 0.425 ZNF687
zinc finger protein 687
chr5_-_175896829 0.424 NM_014901
RNF44
ring finger protein 44
chr17_-_23721468 0.419 VTN
vitronectin
chr12_-_7136147 0.419 NM_001733
C1R
complement component 1, r subcomponent
chr19_-_44034797 0.417 NM_001005335
HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr19_+_40465249 0.417 NM_021175
HAMP
hepcidin antimicrobial peptide
chr22_-_37598115 0.414 CBX6
chromobox homolog 6
chr16_-_29664765 0.414 NM_175900
C16orf54
chromosome 16 open reading frame 54
chr17_-_23721420 0.411 VTN
vitronectin
chr5_-_134397470 0.410 PITX1
paired-like homeodomain 1
chr1_-_56817802 0.407 PPAP2B
phosphatidic acid phosphatase type 2B
chr12_-_107551744 0.407 SELPLG
selectin P ligand
chr16_+_56616782 0.405 NM_002428
MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr3_-_71262426 0.402 FOXP1
forkhead box P1
chr6_+_31647854 0.400 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr16_+_56616970 0.399 MMP15
matrix metallopeptidase 15 (membrane-inserted)
chr11_+_57547928 0.398 NM_001005212
OR9Q1
olfactory receptor, family 9, subfamily Q, member 1
chr6_+_43247179 0.396 SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr20_-_57015698 0.395 NM_001336
CTSZ
cathepsin Z
chr2_-_238813365 0.392 NM_001142853
NM_018645
HES6

hairy and enhancer of split 6 (Drosophila)

chr9_-_135232767 0.389 SURF4
surfeit 4
chr11_-_67032125 0.389 CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr10_+_74323344 0.389 NM_152635
OIT3
oncoprotein induced transcript 3
chr12_+_79634820 0.388 NM_005593
MYF5
myogenic factor 5
chr17_+_8132539 0.386 NM_001177801
NM_001177802
NM_016492
RANGRF


RAN guanine nucleotide release factor


chr16_-_727889 0.384 NARFL
nuclear prelamin A recognition factor-like
chr11_-_102001259 0.384 NM_004771
MMP20
matrix metallopeptidase 20
chr1_+_32417846 0.383 TXLNA
taxilin alpha
chr14_+_92188329 0.383 RIN3
Ras and Rab interactor 3
chr1_-_85235210 0.381 NM_153259
MCOLN2
mucolipin 2
chr6_+_26212082 0.381 NM_003542
HIST1H4C
histone cluster 1, H4c
chr22_-_20419975 0.380 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr17_+_37864441 0.379 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr6_+_31661934 0.377 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr17_-_23721351 0.376 VTN
vitronectin
chr12_+_54910086 0.375 NM_173596
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr2_+_75039273 0.375 NM_019896
POLE4
polymerase (DNA-directed), epsilon 4 (p12 subunit)
chr22_+_19699441 0.375 NM_001159554
NM_005446
P2RX6

purinergic receptor P2X, ligand-gated ion channel, 6

chr4_+_1330957 0.374 NM_020894
KIAA1530
KIAA1530
chr19_+_6723705 0.373 NM_005428
VAV1
vav 1 guanine nucleotide exchange factor
chr11_+_129823667 0.373 NM_139055
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chr1_+_157067729 0.369 NM_002432
MNDA
myeloid cell nuclear differentiation antigen
chr2_-_238813284 0.369 HES6
hairy and enhancer of split 6 (Drosophila)
chr15_-_75259714 0.368 PEAK1
NKF3 kinase family member
chr13_+_42034871 0.367 NM_033012
TNFSF11
tumor necrosis factor (ligand) superfamily, member 11
chr4_+_24406283 0.363 SOD3
superoxide dismutase 3, extracellular
chr22_-_40673025 0.362 NM_001002876
NM_024053
CENPM

centromere protein M

chr19_+_45389356 0.361 NM_002446
MAP3K10
mitogen-activated protein kinase kinase kinase 10
chr17_+_37864425 0.361 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr19_+_17527457 0.361 GLT25D1
glycosyltransferase 25 domain containing 1
chr15_-_73792150 0.361 CSPG4
chondroitin sulfate proteoglycan 4
chrX_+_9391314 0.361 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr12_+_56290229 0.359 NM_001111270
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr1_-_26105954 0.358 NM_203399
STMN1
stathmin 1
chr17_+_37864423 0.357 ATP6V0A1
ATPase, H+ transporting, lysosomal V0 subunit a1
chr22_+_21359175 0.356 IGLV3-25
immunoglobulin lambda variable 3-25

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.79 3.74e-02 GO:0030029 actin filament-based process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.32 7.82e-05 GO:0005576 extracellular region
2.40 1.43e-02 GO:0016585 chromatin remodeling complex

Nothing significant found in function category.