Motif ID: TEAD1.p2

Z-value: 6.275


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4



Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_212791597 30.637 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr1_-_212791467 29.769 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr6_-_132314004 22.506 NM_001901
CTGF
connective tissue growth factor
chr3_-_135575925 21.352 NM_016201
AMOTL2
angiomotin like 2
chr4_+_184257337 21.031 NM_024949
WWC2
WW and C2 domain containing 2
chr15_+_37660568 18.769 NM_003246
THBS1
thrombospondin 1
chr19_+_39664706 17.689 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr6_-_128883125 16.104 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr10_+_123862430 15.160 TACC2
transforming, acidic coiled-coil containing protein 2
chr11_-_6298284 14.986 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr2_-_160972606 14.324 RBMS1
RNA binding motif, single stranded interacting protein 1
chr5_-_39460687 14.097 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr8_-_38505331 13.774 NM_207412
C8orf86
chromosome 8 open reading frame 86
chr11_-_8788765 12.626 NM_213618
ST5
suppression of tumorigenicity 5
chr6_-_75972286 12.277 NM_004370
NM_080645
COL12A1

collagen, type XII, alpha 1

chr1_+_85819004 11.713 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr5_-_148422799 11.475 NM_024577
SH3TC2
SH3 domain and tetratricopeptide repeats 2
chr16_-_30983909 11.088 NM_001172669
NM_001172670
ZNF668

zinc finger protein 668

chr11_-_8789457 11.041 NM_139157
ST5
suppression of tumorigenicity 5
chr15_+_73728402 10.647 NM_153271
SNX33
sorting nexin 33
chr17_-_37828643 10.571 NM_012232
PTRF
polymerase I and transcript release factor
chr6_-_42218692 10.483 NM_001164446
C6orf132
chromosome 6 open reading frame 132
chr12_-_78608873 9.843 NM_002583
PAWR
PRKC, apoptosis, WT1, regulator
chr5_-_39460787 9.814 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr10_-_125843092 9.620 CHST15
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chrX_-_10548458 9.286 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr4_-_152368492 9.053 SH3D19
SH3 domain containing 19
chr3_-_115825742 8.975 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr1_+_78126787 8.913 NM_001172309
NM_144573
NEXN

nexilin (F actin binding protein)

chr10_+_102782151 8.704 SFXN3
sideroflexin 3
chr11_+_113671744 8.639 NM_006169
NNMT
nicotinamide N-methyltransferase
chr7_+_134114701 8.257 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr17_-_15495534 8.040 TRIM16
tripartite motif containing 16
chr12_+_27568311 8.032 NM_001198915
NM_001198916
NM_003622
NM_177444
PPFIBP1



PTPRF interacting protein, binding protein 1 (liprin beta 1)



chr14_-_88090641 7.959 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr10_-_99436889 7.630 NM_021732
AVPI1
arginine vasopressin-induced 1
chr11_-_2907169 7.556 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr12_-_119172339 7.538 NM_025157
PXN
paxillin
chr7_+_134114912 7.529 CALD1
caldesmon 1
chr2_-_189752575 7.514 NM_000393
COL5A2
collagen, type V, alpha 2
chr8_+_1759502 7.389 NM_014629
ARHGEF10
Rho guanine nucleotide exchange factor (GEF) 10
chr1_-_16355013 7.305 NM_004431
EPHA2
EPH receptor A2
chr16_-_62573 7.272 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr1_-_207892296 6.768 NM_001127641
LAMB3
laminin, beta 3
chr1_-_207892420 6.752 NM_000228
LAMB3
laminin, beta 3
chr10_+_102782156 6.733 SFXN3
sideroflexin 3
chr2_+_102125616 6.667 IL1R1
interleukin 1 receptor, type I
chr15_-_58477407 6.641 NM_001002857
NM_001002858
NM_001136015
NM_004039
ANXA2



annexin A2



chr11_-_85108030 6.613 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr9_+_88953378 6.586 NM_001001709
C9orf170
chromosome 9 open reading frame 170
chr5_-_151046638 6.571 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr1_-_199704773 6.539 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr5_-_151046680 6.472 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr5_-_39461054 6.455 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr7_+_115952279 6.388 NM_001172895
CAV1
caveolin 1, caveolae protein, 22kDa
chr10_-_116382089 6.317 ABLIM1
actin binding LIM protein 1
chr15_+_61122139 6.263 TPM1
tropomyosin 1 (alpha)
chr11_+_93394025 6.258 NM_001098672
HEPHL1
hephaestin-like 1
chr11_+_66580884 6.220 RHOD
ras homolog gene family, member D
chr7_+_134114957 6.181 CALD1
caldesmon 1
chr11_-_85107569 6.125 NM_206929
SYTL2
synaptotagmin-like 2
chr11_+_66580861 6.070 NM_014578
RHOD
ras homolog gene family, member D
chr2_-_158439868 5.903 NM_001105
ACVR1
activin A receptor, type I
chr14_-_22516271 5.903 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr12_-_94708641 5.897 NM_021229
NTN4
netrin 4
chr15_+_61121806 5.895 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
TPM1





tropomyosin 1 (alpha)





chrX_-_83644054 5.879 NM_001177478
NM_001177479
NM_144657
HDX


highly divergent homeobox


chr10_-_33287184 5.872 NM_002211
ITGB1
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
chr3_-_113842350 5.867 CCDC80
coiled-coil domain containing 80
chr6_+_144040751 5.733 NM_001100164
NM_001100165
PHACTR2

phosphatase and actin regulator 2

chr1_+_24522116 5.698 NM_021180
GRHL3
grainyhead-like 3 (Drosophila)
chr3_-_113842133 5.661 CCDC80
coiled-coil domain containing 80
chr9_+_90339835 5.641 NM_001161625
NM_145283
NXNL2

nucleoredoxin-like 2

chr16_-_21344158 5.578 NM_130464
NPIPL3
nuclear pore complex interacting protein-like 3
chr6_-_134538762 5.566 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr9_+_111927601 5.561 NM_001136562
AKAP2
A kinase (PRKA) anchor protein 2
chr10_-_17699309 5.554 PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr14_+_54102518 5.489 LOC644925
hypothetical LOC644925
chr10_-_90702490 5.470 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chrX_-_114703273 5.424


chr12_+_51728999 5.410 NM_015319
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_-_113841941 5.345 CCDC80
coiled-coil domain containing 80
chr6_-_75972473 5.338 COL12A1
collagen, type XII, alpha 1
chr11_-_47427263 5.331 NM_005055
NM_032645
RAPSN

receptor-associated protein of the synapse

chr7_+_39739690 5.323 NCRNA00265
non-protein coding RNA 265
chr9_+_117955890 5.264 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr9_+_136673534 5.189 COL5A1
collagen, type V, alpha 1
chr3_-_113842255 5.185 CCDC80
coiled-coil domain containing 80
chr1_+_181422016 5.111 LAMC2
laminin, gamma 2
chr8_-_37847095 5.051 RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr11_+_1812115 5.050 NM_138567
SYT8
synaptotagmin VIII
chr3_-_113841967 5.049 CCDC80
coiled-coil domain containing 80
chr3_-_113842237 5.041 CCDC80
coiled-coil domain containing 80
chr6_-_143307976 5.033 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr8_+_70541412 5.026 NM_001128204
NM_015170
SULF1

sulfatase 1

chr8_-_42184194 5.005 PLAT
plasminogen activator, tissue
chr3_-_113842553 5.000 CCDC80
coiled-coil domain containing 80
chr6_+_83130220 4.904 TPBG
trophoblast glycoprotein
chr3_-_113842652 4.856 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr3_+_191588354 4.852 NM_006580
CLDN16
claudin 16
chr14_+_31615922 4.823 ARHGAP5
Rho GTPase activating protein 5
chr17_-_24973940 4.791 CORO6
coronin 6
chr1_+_114323552 4.745 NM_020190
OLFML3
olfactomedin-like 3
chr8_-_108579270 4.690 NM_001146
ANGPT1
angiopoietin 1
chr19_+_41980248 4.687 LOC284408
hypothetical LOC284408
chr1_+_216585298 4.679 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr5_+_38882017 4.659 OSMR
oncostatin M receptor
chr6_-_134538526 4.634 SGK1
serum/glucocorticoid regulated kinase 1
chr17_+_71229151 4.591 ITGB4
integrin, beta 4
chrX_-_13307425 4.572


chr2_-_192419896 4.560 SDPR
serum deprivation response
chr8_-_42184350 4.543 NM_000930
NM_033011
PLAT

plasminogen activator, tissue

chr7_+_115952325 4.508 CAV1
caveolin 1, caveolae protein, 22kDa
chr6_+_41712907 4.484 MDFI
MyoD family inhibitor
chr6_+_30958672 4.351 DDR1
discoidin domain receptor tyrosine kinase 1
chr19_-_45912817 4.282 ADCK4
aarF domain containing kinase 4
chrX_-_53327473 4.256 NM_015075
IQSEC2
IQ motif and Sec7 domain 2
chr1_-_1283770 4.250 NM_032348
MXRA8
matrix-remodelling associated 8
chr15_-_39973566 4.117 NM_016642
SPTBN5
spectrin, beta, non-erythrocytic 5
chr1_-_151848039 4.089 S100A16
S100 calcium binding protein A16
chr18_+_50646616 4.083 NM_004163
RAB27B
RAB27B, member RAS oncogene family
chr17_+_71229191 4.057 ITGB4
integrin, beta 4
chr5_-_140875591 4.052 DIAPH1
diaphanous homolog 1 (Drosophila)
chr10_+_6284845 4.029 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr16_+_22432344 4.013 NM_001135865
LOC100132247
NPIPL3
nuclear pore complex interacting protein related gene
nuclear pore complex interacting protein-like 3
chr10_-_123346148 3.995 NM_001144915
FGFR2
fibroblast growth factor receptor 2
chr2_+_157000225 3.989 GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr15_-_67494412 3.974 LOC145694
hypothetical LOC145694
chr14_-_22515725 3.972 JUB
jub, ajuba homolog (Xenopus laevis)
chr19_-_56204615 3.970 NM_012315
KLK9
kallikrein-related peptidase 9
chr2_-_192420168 3.949 NM_004657
SDPR
serum deprivation response
chr2_+_157000197 3.926 NM_001083112
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr5_+_131657964 3.886 NM_003059
SLC22A4
solute carrier family 22 (organic cation/ergothioneine transporter), member 4
chr6_+_123152044 3.843 SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr10_-_88720908 3.820 LOC100133190
hypothetical LOC100133190
chr1_-_201411533 3.817 NM_004997
MYBPH
myosin binding protein H
chr12_+_13044604 3.817 HTR7P1
5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
chr1_-_27604656 3.809 WASF2
WAS protein family, member 2
chr1_+_238321794 3.778 NM_020066
FMN2
formin 2
chr12_-_15706340 3.773 EPS8
epidermal growth factor receptor pathway substrate 8
chr10_+_23768203 3.772 NM_001145373
OTUD1
OTU domain containing 1
chr4_+_15089931 3.696 CC2D2A
coiled-coil and C2 domain containing 2A
chr5_-_38881636 3.662


chr7_+_115952074 3.648 NM_001753
CAV1
caveolin 1, caveolae protein, 22kDa
chr18_-_51219880 3.598 TCF4
transcription factor 4
chr2_+_102169864 3.594 NM_003854
IL1RL2
interleukin 1 receptor-like 2
chr3_-_65999548 3.587 NM_001033057
NM_004742
NM_015520
MAGI1


membrane associated guanylate kinase, WW and PDZ domain containing 1


chr6_+_134251940 3.568 NM_198392
NM_003206
TCF21

transcription factor 21

chr1_+_181421984 3.549 LAMC2
laminin, gamma 2
chr6_+_134251957 3.499 TCF21
transcription factor 21
chr17_+_7199178 3.480 NM_198154
TMEM95
transmembrane protein 95
chr7_-_137337352 3.470 CREB3L2
cAMP responsive element binding protein 3-like 2
chr5_-_138822475 3.451 NM_001077693
ECSCR
endothelial cell-specific chemotaxis regulator
chr2_+_67477935 3.445 NM_019002
ETAA1
Ewing tumor-associated antigen 1
chr15_-_40537002 3.350 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr1_+_181421796 3.330 NM_005562
NM_018891
LAMC2

laminin, gamma 2

chr3_+_138020550 3.292 NM_001097599
NM_001097600
NM_025246
TMEM22


transmembrane protein 22


chr6_+_31190505 3.285 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr10_+_91077581 3.281 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr11_-_14336606 3.280 NM_001177315
NM_001102669
RRAS2

related RAS viral (r-ras) oncogene homolog 2

chr12_-_12310969 3.275 NM_002336
LRP6
low density lipoprotein receptor-related protein 6
chr17_+_7195931 3.251 NM_001002914
KCTD11
potassium channel tetramerisation domain containing 11
chr17_+_71229110 3.249 NM_000213
NM_001005731
ITGB4

integrin, beta 4

chr19_-_54063522 3.244 NM_001161354
NM_020904
PLEKHA4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr15_-_93671314 3.242 LOC400456
hypothetical LOC400456
chr5_+_38881719 3.235 NM_003999
OSMR
oncostatin M receptor
chr5_+_121493113 3.224 NM_207317
ZNF474
zinc finger protein 474
chr12_+_26239755 3.212 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr19_-_14467890 3.193 GIPC1
GIPC PDZ domain containing family, member 1
chr7_-_137337318 3.193 CREB3L2
cAMP responsive element binding protein 3-like 2
chr1_-_208046011 3.159 NM_006147
IRF6
interferon regulatory factor 6
chr2_+_73911477 3.140 STAMBP
STAM binding protein
chr19_-_45912832 3.125 NM_001142555
ADCK4
aarF domain containing kinase 4
chr14_+_31615959 3.104 ARHGAP5
Rho GTPase activating protein 5
chr19_-_14467939 3.094 NM_005716
NM_202467
NM_202468
NM_202469
NM_202470
NM_202494
GIPC1





GIPC PDZ domain containing family, member 1





chr12_-_13044467 3.050 NM_015987
HEBP1
heme binding protein 1
chr7_-_137337354 3.019 NM_194071
CREB3L2
cAMP responsive element binding protein 3-like 2
chr9_-_16717887 3.005 BNC2
basonuclin 2
chr12_-_13044448 2.990 HEBP1
heme binding protein 1
chr5_+_76150637 2.952 F2RL1
coagulation factor II (thrombin) receptor-like 1
chr6_+_83129641 2.922 NM_006670
TPBG
trophoblast glycoprotein
chr10_+_88720477 2.913 NM_133447
AGAP11
ankyrin repeat and GTPase domain Arf GTPase activating protein 11
chr5_+_38881716 2.905 NM_001168355
OSMR
oncostatin M receptor
chr2_-_75641587 2.902 NM_001135032
FAM176A
family with sequence similarity 176, member A
chr12_-_13044314 2.899 HEBP1
heme binding protein 1
chr11_-_117941801 2.895 NM_001168618
NM_020153
IFT46

intraflagellar transport 46 homolog (Chlamydomonas)

chr12_-_27126721 2.885 NM_001080406
C12orf71
chromosome 12 open reading frame 71
chr16_+_30815428 2.882 NM_001142544
NM_001330
CTF1

cardiotrophin 1

chrX_+_114701665 2.856 PLS3
plastin 3
chr2_-_75641535 2.849 FAM176A
family with sequence similarity 176, member A
chr3_+_113061218 2.844 NM_001134439
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr4_-_89963177 2.818 NM_001015045
FAM13A
family with sequence similarity 13, member A
chr18_-_44723116 2.816 NM_001190823
SMAD7
SMAD family member 7
chr1_-_24311212 2.813 NM_152372
MYOM3
myomesin family, member 3
chr5_+_150138489 2.779 C5orf62
chromosome 5 open reading frame 62
chr5_-_16989371 2.773 NM_012334
MYO10
myosin X
chr15_-_46725087 2.762 NM_000138
FBN1
fibrillin 1
chr8_-_116750427 2.708 TRPS1
trichorhinophalangeal syndrome I
chr15_+_40353657 2.707 NM_198141
GANC
glucosidase, alpha; neutral C
chr20_+_34603290 2.673 NM_006097
NM_181526
MYL9

myosin, light chain 9, regulatory


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.94 7.44e-04 GO:0007155 cell adhesion
1.94 7.44e-04 GO:0022610 biological adhesion
1.41 2.95e-03 GO:0048731 system development
1.60 5.82e-03 GO:0009966 regulation of signal transduction
2.40 7.01e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.35 1.68e-02 GO:0048856 anatomical structure development
1.55 1.86e-02 GO:0009653 anatomical structure morphogenesis
2.40 1.93e-02 GO:0061061 muscle structure development
2.71 2.06e-02 GO:0007517 muscle organ development
1.49 2.14e-02 GO:0007166 cell surface receptor linked signaling pathway
1.70 3.16e-02 GO:0048468 cell development
1.41 3.32e-02 GO:0042221 response to chemical stimulus
2.32 3.76e-02 GO:0001944 vasculature development
1.30 3.85e-02 GO:0023052 signaling
1.46 4.13e-02 GO:0048513 organ development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.93 3.42e-07 GO:0044421 extracellular region part
4.22 1.25e-06 GO:0044420 extracellular matrix part
1.57 6.43e-06 GO:0005576 extracellular region
5.04 8.43e-06 GO:0005604 basement membrane
2.47 1.55e-05 GO:0031012 extracellular matrix
2.52 8.42e-05 GO:0005578 proteinaceous extracellular matrix
1.29 1.51e-03 GO:0071944 cell periphery
1.76 2.67e-03 GO:0005615 extracellular space
1.28 4.60e-03 GO:0005886 plasma membrane
13.83 2.38e-02 GO:0001527 microfibril

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.36 8.02e-04 GO:0003779 actin binding
3.49 1.65e-03 GO:0019838 growth factor binding
1.18 1.07e-02 GO:0005515 protein binding
1.75 2.69e-02 GO:0005509 calcium ion binding
2.96 4.46e-02 GO:0008201 heparin binding
2.66 4.55e-02 GO:0005539 glycosaminoglycan binding