Motif ID: DBP.p2

Z-value: 2.533


Transcription factors associated with DBP.p2:

Gene SymbolEntrez IDGene Name
DBP 1628 D site of albumin promoter (albumin D-box) binding protein



Activity profile for motif DBP.p2.

activity profile for motif DBP.p2


Sorted Z-values histogram for motif DBP.p2

Sorted Z-values for motif DBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of DBP.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_115826481 6.166 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr2_+_228386800 4.619 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr11_-_16380967 3.931 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr4_-_186969041 3.782 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr4_-_186969202 3.619 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr4_-_23500706 3.541 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr7_+_116238309 3.415 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr2_-_88208650 3.045 NM_001443
FABP1
fatty acid binding protein 1, liver
chr3_-_115825742 2.854 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr4_-_159313613 2.801 NM_001031700
NM_001128424
FAM198B

family with sequence similarity 198, member B

chr14_+_99555471 2.749 EVL
Enah/Vasp-like
chr4_-_159313167 2.706 NM_016613
FAM198B
family with sequence similarity 198, member B
chr1_-_171442937 2.609 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr6_+_131190237 2.493 NM_001195597
LOC285733
hypothetical LOC285733
chr20_-_22512893 2.460 FOXA2
forkhead box A2
chr8_-_37576515 2.435 LOC157860
hypothetical protein LOC157860
chr3_+_153499883 2.433 NM_207293
NM_207294
NM_207295
NM_207296
NM_207297
MBNL1




muscleblind-like (Drosophila)




chr4_-_159312973 2.432 FAM198B
family with sequence similarity 198, member B
chr13_+_96726197 2.344 MBNL2
muscleblind-like 2 (Drosophila)
chr3_-_150578023 2.282 TM4SF1
transmembrane 4 L six family member 1
chr3_-_150578103 2.230 TM4SF1
transmembrane 4 L six family member 1
chr20_+_31059174 2.173 BPIL1
bactericidal/permeability-increasing protein-like 1
chr2_-_164300758 2.170 NM_018086
FIGN
fidgetin
chr3_+_186529376 2.170 MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr20_+_31059038 2.169 NM_025227
BPIL1
bactericidal/permeability-increasing protein-like 1
chr13_+_96726415 2.158 MBNL2
muscleblind-like 2 (Drosophila)
chr10_+_7785347 2.153 ITIH2
inter-alpha (globulin) inhibitor H2
chr20_+_31059115 2.138 BPIL1
bactericidal/permeability-increasing protein-like 1
chr10_+_685887 2.137 C10orf108
chromosome 10 open reading frame 108
chr20_-_22513050 2.127 NM_021784
FOXA2
forkhead box A2
chr10_+_7785290 2.048 ITIH2
inter-alpha (globulin) inhibitor H2
chr1_+_57093030 2.001 NM_000562
C8A
complement component 8, alpha polypeptide
chr1_+_114323552 1.982 NM_020190
OLFML3
olfactomedin-like 3
chr3_+_187813553 1.962 AHSG
alpha-2-HS-glycoprotein
chr2_-_192419896 1.874 SDPR
serum deprivation response
chr16_+_85169615 1.833 NM_005250
FOXL1
forkhead box L1
chrX_+_10084984 1.824 NM_001830
CLCN4
chloride channel 4
chr2_+_127892459 1.820 NM_000312
PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr3_-_147361912 1.816 NM_000935
NM_182943
PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr2_+_127892489 1.806 PROC
protein C (inactivator of coagulation factors Va and VIIIa)
chr3_+_187813538 1.794 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr16_-_73839638 1.793 NM_001170719
BCAR1
breast cancer anti-estrogen resistance 1
chr3_+_187813405 1.756 AHSG
alpha-2-HS-glycoprotein
chr2_-_152538694 1.739 NM_001005747
CACNB4
calcium channel, voltage-dependent, beta 4 subunit
chr4_-_155731288 1.739 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr3_-_150422474 1.715 NM_000096
CP
ceruloplasmin (ferroxidase)
chr1_-_154205675 1.685 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr12_-_23995220 1.675 SOX5
SRY (sex determining region Y)-box 5
chr3_-_147361626 1.672 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr7_+_100557098 1.648 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr12_+_99391870 1.628 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr12_-_88270369 1.599 DUSP6
dual specificity phosphatase 6
chr12_+_99391681 1.584 NM_005123
NR1H4
nuclear receptor subfamily 1, group H, member 4
chr12_-_88270128 1.580 DUSP6
dual specificity phosphatase 6
chrX_+_115481774 1.554 NM_007231
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr9_-_74757735 1.541 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr16_+_14187965 1.515 MKL2
MKL/myocardin-like 2
chr10_-_31328426 1.504 NM_001143769
ZNF438
zinc finger protein 438
chr1_-_53972464 1.500 NM_147193
GLIS1
GLIS family zinc finger 1
chr4_-_159311959 1.479 FAM198B
family with sequence similarity 198, member B
chr17_-_7023378 1.479 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr4_+_74491272 1.476 ALB
albumin
chr12_-_88270375 1.469 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr6_-_131333173 1.465 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr10_-_73953699 1.446 NM_001195519
CBARA1
calcium binding atopy-related autoantigen 1
chr5_-_111119846 1.440 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr19_-_56549853 1.382 NM_001014763
ETFB
electron-transfer-flavoprotein, beta polypeptide
chr10_+_7785331 1.370 ITIH2
inter-alpha (globulin) inhibitor H2
chr17_-_36346240 1.364 KRT23
keratin 23 (histone deacetylase inducible)
chr9_+_115303527 1.347 NM_130795
RGS3
regulator of G-protein signaling 3
chr10_+_104525877 1.341 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr5_+_61910318 1.338 NM_181506
LRRC70
leucine rich repeat containing 70
chr13_-_47885018 1.334 LPAR6
lysophosphatidic acid receptor 6
chr6_-_149847718 1.329 ZC3H12D
zinc finger CCCH-type containing 12D
chr2_-_189752575 1.308 NM_000393
COL5A2
collagen, type V, alpha 2
chrX_-_50403412 1.295 SHROOM4
shroom family member 4
chr13_+_92677012 1.290 NM_005708
GPC6
glypican 6
chr2_+_62787534 1.290 NM_001142614
EHBP1
EH domain binding protein 1
chr16_-_11918019 1.287 NM_001130007
GSPT1
G1 to S phase transition 1
chr16_-_11282595 1.285 NM_002761
PRM1
protamine 1
chr2_-_21120314 1.272 APOB
apolipoprotein B (including Ag(x) antigen)
chrX_+_49718954 1.270 NM_000084
CLCN5
chloride channel 5
chr9_+_4829763 1.268 RCL1
RNA terminal phosphate cyclase-like 1
chr2_-_21120420 1.266 NM_000384
APOB
apolipoprotein B (including Ag(x) antigen)
chr9_+_129900590 1.261 SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chrX_+_115481848 1.251 SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr9_+_129900637 1.233 NM_052901
NM_001006643
SLC25A25

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25

chr11_+_20000938 1.232 NAV2
neuron navigator 2
chr13_+_96672541 1.230 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr13_-_47885248 1.227 LPAR6
lysophosphatidic acid receptor 6
chr5_+_147754467 1.227 FBXO38
F-box protein 38
chr1_-_23758871 1.226 NM_002167
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr12_-_88269884 1.213 DUSP6
dual specificity phosphatase 6
chr12_-_23995109 1.190 SOX5
SRY (sex determining region Y)-box 5
chr17_-_38421363 1.183 VAT1
vesicle amine transport protein 1 homolog (T. californica)
chr2_+_108360798 1.182 NM_006588
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr9_+_115396020 1.168 NM_144489
RGS3
regulator of G-protein signaling 3
chr9_+_12764988 1.150 NM_203403
C9orf150
chromosome 9 open reading frame 150
chrX_-_105169370 1.138 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr3_-_185578621 1.125 NM_000460
NM_001177597
NM_001177598
THPO


thrombopoietin


chr11_+_20001130 1.125 NM_001111019
NAV2
neuron navigator 2
chr7_+_134226690 1.122 NM_033139
NM_033140
CALD1

caldesmon 1

chr17_-_31332568 1.121 NM_004590
CCL16
chemokine (C-C motif) ligand 16
chr2_-_215998181 1.117 FN1
fibronectin 1
chr7_+_134226727 1.116 CALD1
caldesmon 1
chr3_-_150578207 1.114 NM_014220
TM4SF1
transmembrane 4 L six family member 1
chr1_+_82038669 1.110 NM_012302
LPHN2
latrophilin 2
chr3_-_150578148 1.106 TM4SF1
transmembrane 4 L six family member 1
chr2_-_21120398 1.105 APOB
apolipoprotein B (including Ag(x) antigen)
chr5_-_95184121 1.103 GLRX
glutaredoxin (thioltransferase)
chr2_+_138438277 1.097 NM_001024074
NM_001024075
NM_006895
HNMT


histamine N-methyltransferase


chr2_+_241193492 1.086 NM_001195381
NM_001195382
GPR35

G protein-coupled receptor 35

chr2_+_33213111 1.080 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr5_+_176449156 1.080 NM_022963
FGFR4
fibroblast growth factor receptor 4
chr6_+_43565192 1.075 NM_001146017
TJAP1
tight junction associated protein 1 (peripheral)
chr6_+_45404031 1.071 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr10_-_92671005 1.061 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr14_-_22516271 1.057 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr11_-_85107569 1.055 NM_206929
SYTL2
synaptotagmin-like 2
chr1_-_23758503 1.051 ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr3_-_147361465 1.049 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr6_+_26153590 1.045 NM_003531
HIST1H3C
histone cluster 1, H3c
chr4_-_16509126 1.035 LDB2
LIM domain binding 2
chr18_-_21184824 1.031


chr3_-_150858274 1.019 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr18_-_63333487 0.988 DSEL
dermatan sulfate epimerase-like
chr5_-_95184221 0.985 NM_001118890
NM_002064
GLRX

glutaredoxin (thioltransferase)

chr19_-_47638890 0.985 NM_198477
CXCL17
chemokine (C-X-C motif) ligand 17
chr4_-_100284395 0.984 NM_000670
ADH4
alcohol dehydrogenase 4 (class II), pi polypeptide
chr22_+_36531059 0.983 NM_005318
H1F0
H1 histone family, member 0
chr3_-_33675484 0.979 CLASP2
cytoplasmic linker associated protein 2
chr6_+_30702586 0.966 NM_024909
NM_001031722
NM_001190724
ATAT1


alpha tubulin acetyltransferase 1


chr12_+_54760211 0.953 ERBB3
v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chrX_+_70359780 0.946 NM_000166
GJB1
gap junction protein, beta 1, 32kDa
chr9_+_18464090 0.944 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr22_+_19458378 0.941 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr7_-_75876830 0.933 NM_080744
SRCRB4D
scavenger receptor cysteine rich domain containing, group B (4 domains)
chr13_-_45577144 0.931 NM_001872
NM_016413
CPB2

carboxypeptidase B2 (plasma)

chr13_-_33148899 0.927 STARD13
StAR-related lipid transfer (START) domain containing 13
chr4_+_74493174 0.922 ALB
albumin
chr9_+_18464138 0.916 ADAMTSL1
ADAMTS-like 1
chr14_-_23846904 0.909 CIDEB
cell death-inducing DFFA-like effector b
chr4_+_74493218 0.905 ALB
albumin
chr20_+_5935897 0.901 NM_001127458
CRLS1
cardiolipin synthase 1
chr17_+_24394043 0.900 NM_016518
PIPOX
pipecolic acid oxidase
chr15_-_88150823 0.899 ANPEP
alanyl (membrane) aminopeptidase
chr14_-_23847024 0.890 CIDEB
cell death-inducing DFFA-like effector b
chr4_+_74493301 0.889 ALB
albumin
chr4_+_71806538 0.886 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr11_+_62893836 0.882 NM_080866
SLC22A9
solute carrier family 22 (organic anion transporter), member 9
chr9_-_83494198 0.880 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr3_-_115960807 0.866 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr4_+_74493266 0.857 ALB
albumin
chr6_+_136214495 0.855 NM_018945
PDE7B
phosphodiesterase 7B
chr1_-_150070849 0.852 NM_005060
RORC
RAR-related orphan receptor C
chr3_-_188935363 0.844 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr15_+_64782468 0.827 SMAD6
SMAD family member 6
chr4_+_74493331 0.826 ALB
albumin
chr11_+_129496792 0.823 APLP2
amyloid beta (A4) precursor-like protein 2
chr12_+_51783554 0.821 SOAT2
sterol O-acyltransferase 2
chr10_-_91394881 0.821 PANK1
pantothenate kinase 1
chr13_+_48582389 0.818 NM_014923
FNDC3A
fibronectin type III domain containing 3A
chr14_-_23846993 0.814 CIDEB
cell death-inducing DFFA-like effector b
chr20_+_19815075 0.813 RIN2
Ras and Rab interactor 2
chr5_+_71538456 0.804 MAP1B
microtubule-associated protein 1B
chr14_+_31100330 0.803 NM_025152
NUBPL
nucleotide binding protein-like
chr7_-_121571472 0.798 NM_005763
AASS
aminoadipate-semialdehyde synthase
chr17_-_23721430 0.797 VTN
vitronectin
chr11_-_95715976 0.781 NM_032427
MAML2
mastermind-like 2 (Drosophila)
chr7_-_78920806 0.779 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chrX_-_33139349 0.777 NM_004006
DMD
dystrophin
chr13_-_47885653 0.776 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chrX_+_70360184 0.771 GJB1
gap junction protein, beta 1, 32kDa
chr13_-_49597776 0.770 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chr15_-_31147376 0.769 NM_001103184
FMN1
formin 1
chr6_+_26333361 0.767 NM_003532
HIST1H3E
histone cluster 1, H3e
chr2_-_174538675 0.760 NM_001172712
NM_003111
SP3

Sp3 transcription factor

chr2_+_66519949 0.757 MEIS1
Meis homeobox 1
chr3_-_42892636 0.757 NM_004391
CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chr11_+_101488380 0.755 NM_001195045
YAP1
Yes-associated protein 1
chr22_+_36531178 0.752 H1F0
H1 histone family, member 0
chr14_-_23847000 0.750 CIDEB
cell death-inducing DFFA-like effector b
chr13_+_23742846 0.749 SPATA13
spermatogenesis associated 13
chr22_+_30072739 0.749 FLJ20464
hypothetical protein FLJ20464
chr17_+_55269974 0.742


chr11_+_22652894 0.740 NM_005256
GAS2
growth arrest-specific 2
chr5_-_172688024 0.740 STC2
stanniocalcin 2
chr16_-_71650034 0.735 NM_001164766
ZFHX3
zinc finger homeobox 3
chr14_-_93924663 0.733 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr4_-_16509354 0.729 LDB2
LIM domain binding 2
chr13_+_97856148 0.722


chr19_-_62680703 0.721 NM_001024596
NM_001144068
ZNF772

zinc finger protein 772

chr3_-_52844274 0.714 NM_205853
MUSTN1
musculoskeletal, embryonic nuclear protein 1
chr18_+_3443771 0.714 NM_173211
TGIF1
TGFB-induced factor homeobox 1
chr17_+_69950782 0.709 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr1_-_176205672 0.702 NM_033127
SEC16B
SEC16 homolog B (S. cerevisiae)
chr10_+_7785235 0.699 NM_002216
ITIH2
inter-alpha (globulin) inhibitor H2
chr1_+_84382575 0.696 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr9_+_96806235 0.693 C9orf3
chromosome 9 open reading frame 3
chr3_-_48446405 0.686 NM_001130082
PLXNB1
plexin B1

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.29 3.00e-07 GO:0032502 developmental process
1.31 5.76e-07 GO:0007275 multicellular organismal development
1.34 1.93e-06 GO:0048731 system development
1.30 9.09e-06 GO:0048856 anatomical structure development
1.21 3.55e-05 GO:0032501 multicellular organismal process
1.43 1.51e-04 GO:0007399 nervous system development
1.94 8.66e-04 GO:0060284 regulation of cell development
1.70 2.87e-03 GO:0048585 negative regulation of response to stimulus
1.38 3.14e-03 GO:0009653 anatomical structure morphogenesis
1.95 3.51e-03 GO:0061061 muscle structure development
1.31 3.92e-03 GO:0048869 cellular developmental process
1.33 3.93e-03 GO:0048583 regulation of response to stimulus
1.31 5.10e-03 GO:0030154 cell differentiation
1.38 5.66e-03 GO:0009966 regulation of signal transduction
2.38 7.46e-03 GO:0030111 regulation of Wnt receptor signaling pathway
1.46 1.15e-02 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.31 1.18e-02 GO:0048513 organ development
2.09 1.20e-02 GO:0007517 muscle organ development
1.72 1.48e-02 GO:0009968 negative regulation of signal transduction
1.48 1.74e-02 GO:0040011 locomotion
1.53 2.73e-02 GO:0010628 positive regulation of gene expression
1.33 3.18e-02 GO:0023051 regulation of signaling
2.25 3.61e-02 GO:0060537 muscle tissue development

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.53 9.69e-03 GO:0030054 cell junction
1.30 2.45e-02 GO:0005856 cytoskeleton

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 1.18e-04 GO:0005515 protein binding
1.06 2.07e-02 GO:0005488 binding
4.07 4.52e-02 GO:0030971 receptor tyrosine kinase binding