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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: E2F1..5.p2

Z-value: 3.814

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_23729871	7.727		E2F2	E2F transcription factor 2
chr1_-_23730298	7.495	NM_004091	E2F2	E2F transcription factor 2
chr6_+_135544138	6.043	NM_001130172 NM_001130173 NM_001161656 NM_001161657 NM_001161658 NM_001161659 NM_001161660 NM_005375	MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr6_+_135544214	5.663		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr6_+_135544170	5.469		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr20_-_35157744	5.057		RBL1	retinoblastoma-like 1 (p107)
chr20_-_35157815	4.783	NM_002895 NM_183404	RBL1	retinoblastoma-like 1 (p107)
chr22_+_34126104	4.493	NM_006739	MCM5	minichromosome maintenance complex component 5
chr22_+_34126154	4.285		MCM5	minichromosome maintenance complex component 5
chr10_+_124885556	4.141	NM_001105574	HMX3	H6 family homeobox 3
chr9_-_122679387	4.122	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr22_-_18484695	4.044		TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr22_+_18485145	4.040		RANBP1	RAN binding protein 1
chr22_+_18485057	3.891		RANBP1	RAN binding protein 1
chr22_+_18485076	3.884		RANBP1	RAN binding protein 1
chr11_-_19219000	3.839	NM_024680	E2F8	E2F transcription factor 8
chr9_-_122679283	3.715		PHF19	PHD finger protein 19
chr22_+_18485095	3.605		RANBP1	RAN binding protein 1
chr1_+_3558958	3.584	NM_005427	TP73	tumor protein p73
chr22_-_18484744	3.567	NM_022727 NM_182984	TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr22_+_18485068	3.525		RANBP1	RAN binding protein 1
chr6_-_26358811	3.496	NM_021018	HIST1H3F	histone cluster 1, H3f
chr20_-_31737731	3.403		E2F1	E2F transcription factor 1
chr1_-_36008009	3.342	NM_001190481 NM_022111	CLSPN	claspin
chr11_-_19219720	3.272		E2F8	E2F transcription factor 8
chr20_-_31737815	3.266	NM_005225	E2F1	E2F transcription factor 1
chr11_-_33847507	3.249		LMO2	LIM domain only 2 (rhombotin-like 1)
chr7_+_50314801	3.011	NM_006060	IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr16_-_30010705	2.999	NM_004608	TBX6	T-box 6
chr22_+_34126294	2.897		MCM5	minichromosome maintenance complex component 5
chr22_+_18484810	2.878	NM_002882	RANBP1	RAN binding protein 1
chr6_-_52257500	2.848	NM_002388	MCM3	minichromosome maintenance complex component 3
chr6_-_52257475	2.486		MCM3	minichromosome maintenance complex component 3
chr6_+_31815703	2.470	NM_002441 NM_025259 NM_172165 NM_172166	MSH5-C6ORF26 MSH5	MSH5-C6orf26 read-through transcript mutS homolog 5 (E. coli)
chr10_+_62208094	2.447	NM_001170406 NM_001170407 NM_001786 NM_033379	CDK1	cyclin-dependent kinase 1
chr2_+_10180145	2.418	NM_001165931	RRM2	ribonucleotide reductase M2
chr2_+_74635019	2.407	NM_001381	DOK1	docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr10_+_62208256	2.404		CDK1	cyclin-dependent kinase 1
chr9_-_98220482	2.368	NM_153695	ZNF367	zinc finger protein 367
chr2_+_10180304	2.356	NM_001034	RRM2	ribonucleotide reductase M2
chr6_+_20510019	2.333	NM_001949	E2F3	E2F transcription factor 3
chr6_-_52257431	2.313		MCM3	minichromosome maintenance complex component 3
chr9_-_98220360	2.289		ZNF367	zinc finger protein 367
chr11_-_33847937	2.275	NM_001142316	LMO2	LIM domain only 2 (rhombotin-like 1)
chr2_+_173927783	2.255	NM_031942 NM_145810	CDCA7	cell division cycle associated 7
chr4_-_56197115	2.222	NM_006681	NMU	neuromedin U
chr9_+_129962292	2.221	NM_024112	C9orf16	chromosome 9 open reading frame 16
chr17_+_26183074	2.189	NM_024857	ATAD5	ATPase family, AAA domain containing 5
chr11_-_33847834	2.166		LMO2	LIM domain only 2 (rhombotin-like 1)
chr19_-_60587414	2.163	NM_001190764	LOC388564	hypothetical protein LOC388564
chr17_+_27288152	2.121	NM_015355	SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr7_-_158190193	2.119	NM_017760	NCAPG2	non-SMC condensin II complex, subunit G2
chr5_-_176671897	2.096	NM_001142935 NM_031300	MXD3	MAX dimerization protein 3
chr11_-_33848013	2.070		LMO2	LIM domain only 2 (rhombotin-like 1)
chr17_+_27288167	2.049		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr7_+_120378052	2.048	NM_019071 NM_198267	ING3	inhibitor of growth family, member 3
chr17_+_26082779	2.041		SUZ12P	suppressor of zeste 12 homolog pseudogene
chr2_+_232281470	1.990	NM_001099285 NM_002823	PTMA	prothymosin, alpha
chr19_-_10166645	1.973	NM_001130823 NM_001379	DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr19_-_10166600	1.969		DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr17_+_27288178	1.919		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr19_-_10540620	1.905	NM_001800 NM_079421	CDKN2D	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr3_+_128799961	1.889		MCM2	minichromosome maintenance complex component 2
chr22_-_37296012	1.869	NM_007068	DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)
chr6_+_24883133	1.830	NM_015895	GMNN	geminin, DNA replication inhibitor
chr16_-_2970474	1.811	NM_004203 NM_182687	PKMYT1	protein kinase, membrane associated tyrosine/threonine 1
chr12_-_131773972	1.804	NM_006231	POLE	polymerase (DNA directed), epsilon
chr16_-_2970390	1.802		PKMYT1	protein kinase, membrane associated tyrosine/threonine 1
chr12_-_131774061	1.798		POLE	polymerase (DNA directed), epsilon
chr17_+_27288253	1.783		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr6_+_27222839	1.783	NM_080596	HIST1H2AH	histone cluster 1, H2ah
chr2_+_232281491	1.754		PTMA	prothymosin, alpha
chr15_-_64436045	1.744	NM_017858	TIPIN	TIMELESS interacting protein
chr12_+_131774225	1.719	NM_018663	PXMP2	peroxisomal membrane protein 2, 22kDa
chr6_-_153345786	1.700	NM_012177	FBXO5	F-box protein 5
chrX_-_53465847	1.688		SMC1A	structural maintenance of chromosomes 1A
chr22_-_19685998	1.669		THAP7	THAP domain containing 7
chrX_+_130985316	1.628	NM_001042452	MST4	serine/threonine protein kinase MST4
chr6_+_27208763	1.618	NM_021064	HIST1H2AG	histone cluster 1, H2ag
chrX_+_130984912	1.603	NM_001042453 NM_016542	MST4	serine/threonine protein kinase MST4
chr3_+_16901455	1.583	NM_001144382	PLCL2	phospholipase C-like 2
chr11_+_817584	1.581	NM_173584	EFCAB4A	EF-hand calcium binding domain 4A
chr2_+_74635354	1.578		DOK1	docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr4_-_105631915	1.559	NM_025212	CXXC4	CXXC finger protein 4
chr10_-_25281510	1.530	NM_020200	PRTFDC1	phosphoribosyl transferase domain containing 1
chr1_-_28113817	1.526	NM_002946	RPA2	replication protein A2, 32kDa
chr19_-_10540328	1.525		CDKN2D	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr15_+_89061579	1.523	NM_000057	BLM	Bloom syndrome, RecQ helicase-like
chr16_+_87397686	1.522	NM_030928	CDT1	chromatin licensing and DNA replication factor 1
chr15_+_38550451	1.513	NM_130468	CHST14	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr19_-_10166536	1.503		DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr1_-_227761038	1.499	NM_012089	ABCB10	ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr17_+_27288374	1.498
chr19_-_10305186	1.483	NM_133452	RAVER1	ribonucleoprotein, PTB-binding 1
chr3_-_150286812	1.480	NM_003071 NM_139048	HLTF	helicase-like transcription factor
chr3_+_144321286	1.476	NM_004267	CHST2	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr19_+_34994701	1.465	NM_001238	CCNE1	cyclin E1
chr17_-_44042924	1.463		HOXB7	homeobox B7
chr10_-_57791025	1.458	NM_001005413 NM_007057 NM_032997	ZWINT	ZW10 interactor
chr7_+_128861471	1.455	NM_001134336 NM_020704	FAM40B	family with sequence similarity 40, member B
chr3_-_140148671	1.452	NM_023067	FOXL2	forkhead box L2
chr6_-_27222556	1.449	NM_080593	HIST1H2BK	histone cluster 1, H2bk
chrX_-_133758812	1.448	NM_001166599 NM_001166600 NM_001170757	FAM122B	family with sequence similarity 122B
chr10_-_57791000	1.446		ZWINT	ZW10 interactor
chr1_-_28113540	1.438		RPA2	replication protein A2, 32kDa
chr7_-_106088565	1.428	NM_175884	FLJ36031	hypothetical protein FLJ36031
chr5_-_37406939	1.418	NM_153485	NUP155	nucleoporin 155kDa
chr1_+_149309703	1.408	NM_144618	GABPB2	GA binding protein transcription factor, beta subunit 2
chr7_+_116380790	1.394		ST7	suppression of tumorigenicity 7
chr1_+_226712430	1.385	NM_175055	HIST3H2BB	histone cluster 3, H2bb
chr7_-_99536966	1.356		MCM7	minichromosome maintenance complex component 7
chr1_-_226712140	1.342	NM_033445	HIST3H2A	histone cluster 3, H2a
chr8_-_120937215	1.334	NM_024094	DSCC1	defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
chr5_-_37406835	1.326		NUP155	nucleoporin 155kDa
chr1_+_210275752	1.323		DTL	denticleless homolog (Drosophila)
chr1_-_26058434	1.322	NM_024037	C1orf135	chromosome 1 open reading frame 135
chr16_+_87397715	1.315		CDT1	chromatin licensing and DNA replication factor 1
chr1_-_24179326	1.311		SRSF10	serine/arginine-rich splicing factor 10
chrX_+_152891184	1.301	NM_003492	TMEM187	transmembrane protein 187
chr19_+_18391423	1.301
chr22_+_49293520	1.301		NCAPH2	non-SMC condensin II complex, subunit H2
chr17_-_43977273	1.299	NM_002145	HOXB2	homeobox B2
chr15_+_30694982	1.299	NM_014783 NM_199357	ARHGAP11A	Rho GTPase activating protein 11A
chr11_+_62380042	1.298	NM_001012662 NM_001012664 NM_002394 NM_001012661 NM_001012663	SLC3A2	solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr8_-_124477869	1.295	NM_014109	ATAD2	ATPase family, AAA domain containing 2
chr12_-_47532171	1.287	NM_004818	DDX23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr17_+_35277942	1.272	NM_198844 NM_199321	ZPBP2	zona pellucida binding protein 2
chr1_+_210275735	1.269		DTL	denticleless homolog (Drosophila)
chr11_+_125001063	1.260		CHEK1	CHK1 checkpoint homolog (S. pombe)
chr6_-_27208507	1.257	NM_021058	HIST1H2BJ	histone cluster 1, H2bj
chr7_-_99536929	1.257		MCM7	minichromosome maintenance complex component 7
chr16_+_29724926	1.250		MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr15_+_62539831	1.242		ZNF609	zinc finger protein 609
chr19_-_17047228	1.242	NM_001011699 NM_033417	HAUS8	HAUS augmin-like complex, subunit 8
chr1_-_91260357	1.238		ZNF644	zinc finger protein 644
chr7_+_116380590	1.231	NM_018412 NM_021908	ST7	suppression of tumorigenicity 7
chr20_-_60415729	1.225	NM_031215	CABLES2	Cdk5 and Abl enzyme substrate 2
chr5_+_126140949	1.219		LMNB1	lamin B1
chr4_+_129950222	1.218	NM_024900 NM_199320	PHF17	PHD finger protein 17
chr19_-_46551172	1.210		TGFB1	transforming growth factor, beta 1
chr12_-_46785682	1.204	NM_014554	SENP1	SUMO1/sentrin specific peptidase 1
chr3_+_128799902	1.200	NM_004526	MCM2	minichromosome maintenance complex component 2
chr12_-_46786107	1.199		SENP1	SUMO1/sentrin specific peptidase 1
chr8_-_27751207	1.198	NM_018492	PBK	PDZ binding kinase
chr16_+_29726195	1.197		MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr11_+_63498590	1.195	NM_004074	COX8A	cytochrome c oxidase subunit VIIIA (ubiquitous)
chr17_-_16197433	1.191	NM_181716	CENPV	centromere protein V
chr16_-_46052596	1.191		ITFG1	integrin alpha FG-GAP repeat containing 1
chr12_-_49897743	1.185		POU6F1	POU class 6 homeobox 1
chr12_+_107047594	1.185	NM_014653	WSCD2	WSC domain containing 2
chr22_-_18484428	1.184		TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr3_+_128799964	1.181		MCM2	minichromosome maintenance complex component 2
chr15_+_39739933	1.180		MGA	MAX gene associated
chr17_+_43081837	1.176		KPNB1	karyopherin (importin) beta 1
chr19_-_46551607	1.173		TGFB1	transforming growth factor, beta 1
chr7_-_44854222	1.171	NM_012412 NM_138635 NM_201436 NM_201516 NM_201517	H2AFV	H2A histone family, member V
chr19_+_53559468	1.163	NM_012451	SYNGR4	synaptogyrin 4
chr6_-_27883662	1.162	NM_003519	HIST1H2BL	histone cluster 1, H2bl
chr7_-_148212312	1.161		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr7_-_148212310	1.158		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr7_-_148212336	1.155	NM_004456 NM_152998	EZH2	enhancer of zeste homolog 2 (Drosophila)
chr9_+_99785277	1.154	NM_006401	ANP32B	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr13_+_113286979	1.148		TFDP1	transcription factor Dp-1
chr7_-_99871981	1.148	NM_145030	C7orf47	chromosome 7 open reading frame 47
chr19_+_868285	1.145	NM_032551	KISS1R	KISS1 receptor
chr17_-_44043278	1.143		HOXB7	homeobox B7
chr3_+_140148765	1.140	NM_001040061	C3orf72	chromosome 3 open reading frame 72
chr19_+_4860447	1.139	NM_001048201	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr3_+_38363299	1.137		XYLB	xylulokinase homolog (H. influenzae)
chr3_+_38363292	1.136		XYLB	xylulokinase homolog (H. influenzae)
chr1_-_91260131	1.122		ZNF644	zinc finger protein 644
chr19_+_55579272	1.121		POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa
chr7_-_99537362	1.118	NM_005916	MCM7	minichromosome maintenance complex component 7
chr16_+_2959362	1.114		PAQR4	progestin and adipoQ receptor family member IV
chr19_-_46551670	1.114	NM_000660	TGFB1	transforming growth factor, beta 1
chr1_+_210275541	1.111	NM_016448	DTL	denticleless homolog (Drosophila)
chr17_-_44043361	1.110	NM_004502	HOXB7	homeobox B7
chr7_-_148212292	1.109		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr8_+_65656164	1.108		BHLHE22	basic helix-loop-helix family, member e22
chr1_-_203985896	1.107		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr20_-_5048443	1.107	NM_182649	PCNA	proliferating cell nuclear antigen
chr16_+_2959342	1.088	NM_152341	PAQR4	progestin and adipoQ receptor family member IV
chr7_-_148212230	1.086		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr2_+_75039273	1.085	NM_019896	POLE4	polymerase (DNA-directed), epsilon 4 (p12 subunit)
chr13_+_113287048	1.085	NM_007111	TFDP1	transcription factor Dp-1
chr3_-_53055078	1.083	NM_001005158 NM_016329	SFMBT1	Scm-like with four mbt domains 1
chr5_-_37406643	1.082	NM_004298	NUP155	nucleoporin 155kDa
chr11_-_107874128	1.080	NM_153705	KDELC2	KDEL (Lys-Asp-Glu-Leu) containing 2
chr16_+_28798735	1.074		ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr11_-_62379788	1.067		SNHG1	small nucleolar RNA host gene 1 (non-protein coding)
chr19_+_50601306	1.060	NM_012099	CD3EAP	CD3e molecule, epsilon associated protein
chr19_+_55579404	1.058	NM_002691	POLD1	polymerase (DNA directed), delta 1, catalytic subunit 125kDa
chr6_+_27883877	1.044	NM_003509	HIST1H2AI HIST1H3F	histone cluster 1, H2ai histone cluster 1, H3f
chr3_-_53054999	1.044		SFMBT1	Scm-like with four mbt domains 1
chr16_+_56983798	1.043	NM_001126129 NM_001126130 NM_022770	GINS3	GINS complex subunit 3 (Psf3 homolog)
chr7_-_99536852	1.037		MCM7	minichromosome maintenance complex component 7
chr2_-_58321947	1.036	NM_001114636 NM_018062	FANCL	Fanconi anemia, complementation group L
chr10_-_98470164	1.029	NM_152309	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1
chr1_-_203985932	1.029
chr15_-_38834706	1.029		FAM82A2	family with sequence similarity 82, member A2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.47	1.37e-28	GO:0007049	cell cycle
2.88	9.57e-26	GO:0051276	chromosome organization
2.58	2.97e-25	GO:0022402	cell cycle process
1.85	1.86e-24	GO:0090304	nucleic acid metabolic process
2.71	2.09e-24	GO:0022403	cell cycle phase
1.73	3.54e-24	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.66	1.98e-19	GO:0006259	DNA metabolic process
2.68	2.17e-19	GO:0000278	mitotic cell cycle
1.59	3.63e-19	GO:0034641	cellular nitrogen compound metabolic process
1.56	6.30e-18	GO:0006807	nitrogen compound metabolic process
4.01	5.77e-17	GO:0006260	DNA replication
1.44	1.78e-16	GO:0044260	cellular macromolecule metabolic process
3.21	1.92e-16	GO:0051325	interphase
1.83	6.12e-16	GO:0006996	organelle organization
3.18	1.15e-15	GO:0051329	interphase of mitotic cell cycle
2.66	4.02e-15	GO:0006325	chromatin organization
4.10	1.18e-13	GO:0000082	G1/S transition of mitotic cell cycle
2.48	3.22e-13	GO:0006974	response to DNA damage stimulus
2.30	1.09e-12	GO:0051726	regulation of cell cycle
2.76	9.95e-12	GO:0006281	DNA repair
4.52	1.21e-11	GO:0031497	chromatin assembly
3.96	2.52e-11	GO:0006323	DNA packaging
4.26	4.19e-11	GO:0065004	protein-DNA complex assembly
1.52	4.40e-11	GO:0071842	cellular component organization at cellular level
1.50	4.77e-11	GO:0071841	cellular component organization or biogenesis at cellular level
4.15	4.83e-11	GO:0071824	protein-DNA complex subunit organization
3.65	5.98e-11	GO:0071103	DNA conformation change
3.79	6.13e-11	GO:0006333	chromatin assembly or disassembly
4.30	6.89e-11	GO:0034728	nucleosome organization
1.43	7.17e-11	GO:0016043	cellular component organization
1.27	1.35e-10	GO:0044237	cellular metabolic process
1.42	2.04e-10	GO:0071840	cellular component organization or biogenesis
1.32	2.16e-10	GO:0043170	macromolecule metabolic process
4.36	5.92e-10	GO:0006334	nucleosome assembly
1.65	6.56e-10	GO:0034645	cellular macromolecule biosynthetic process
2.40	8.96e-10	GO:0000279	M phase
2.59	9.29e-10	GO:0010564	regulation of cell cycle process
1.51	1.43e-09	GO:0044249	cellular biosynthetic process
4.88	1.88e-09	GO:0006261	DNA-dependent DNA replication
1.63	2.05e-09	GO:0009059	macromolecule biosynthetic process
1.13	3.95e-09	GO:0009987	cellular process
1.25	4.35e-09	GO:0044238	primary metabolic process
3.56	4.53e-09	GO:0006310	DNA recombination
2.93	9.94e-09	GO:0071156	regulation of cell cycle arrest
1.47	1.29e-08	GO:0009058	biosynthetic process
2.92	3.08e-08	GO:0000075	cell cycle checkpoint
1.98	3.30e-08	GO:0065003	macromolecular complex assembly
1.88	4.91e-08	GO:0043933	macromolecular complex subunit organization
7.23	5.92e-08	GO:0006271	DNA strand elongation involved in DNA replication
1.58	5.96e-08	GO:0016070	RNA metabolic process
3.68	9.83e-08	GO:0051320	S phase
2.38	1.05e-07	GO:0034622	cellular macromolecular complex assembly
2.15	1.72e-07	GO:0034621	cellular macromolecular complex subunit organization
1.85	2.15e-07	GO:0033554	cellular response to stress
6.75	2.43e-07	GO:0022616	DNA strand elongation
2.35	2.60e-07	GO:0016568	chromatin modification
3.63	2.89e-07	GO:0000084	S phase of mitotic cell cycle
1.20	3.71e-07	GO:0008152	metabolic process
8.23	4.73e-07	GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle
2.00	5.12e-07	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35	6.36e-07	GO:0080090	regulation of primary metabolic process
1.41	6.42e-07	GO:0051171	regulation of nitrogen compound metabolic process
1.67	9.26e-07	GO:0044085	cellular component biogenesis
1.34	9.28e-07	GO:0031323	regulation of cellular metabolic process
1.97	9.85e-07	GO:0051172	negative regulation of nitrogen compound metabolic process
1.35	1.33e-06	GO:0060255	regulation of macromolecule metabolic process
2.44	1.87e-06	GO:0000280	nuclear division
2.44	1.87e-06	GO:0007067	mitosis
1.70	2.22e-06	GO:0022607	cellular component assembly
7.48	2.61e-06	GO:0006270	DNA-dependent DNA replication initiation
1.40	3.12e-06	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.42	3.66e-06	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.44	4.28e-06	GO:0051252	regulation of RNA metabolic process
2.37	5.42e-06	GO:0000087	M phase of mitotic cell cycle
2.00	5.99e-06	GO:0016071	mRNA metabolic process
2.36	6.16e-06	GO:0048285	organelle fission
1.39	1.81e-05	GO:0010468	regulation of gene expression
1.29	2.16e-05	GO:0019222	regulation of metabolic process
1.39	2.65e-05	GO:0010556	regulation of macromolecule biosynthetic process
1.42	2.90e-05	GO:0006355	regulation of transcription, DNA-dependent
1.37	2.94e-05	GO:0031326	regulation of cellular biosynthetic process
1.70	3.53e-05	GO:0010605	negative regulation of macromolecule metabolic process
9.49	4.96e-05	GO:0071897	DNA biosynthetic process
1.36	5.42e-05	GO:0009889	regulation of biosynthetic process
1.85	7.12e-05	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.45	1.01e-04	GO:0010467	gene expression
1.64	1.10e-04	GO:0009892	negative regulation of metabolic process
3.57	2.03e-04	GO:0000216	M/G1 transition of mitotic cell cycle
1.76	3.99e-04	GO:0031327	negative regulation of cellular biosynthetic process
1.71	4.12e-04	GO:0071844	cellular component assembly at cellular level
4.22	4.21e-04	GO:0051053	negative regulation of DNA metabolic process
1.64	4.41e-04	GO:0031324	negative regulation of cellular metabolic process
1.38	4.71e-04	GO:0048523	negative regulation of cellular process
1.77	5.20e-04	GO:0010558	negative regulation of macromolecule biosynthetic process
2.02	5.36e-04	GO:0006397	mRNA processing
1.36	7.12e-04	GO:0048519	negative regulation of biological process
1.60	8.38e-04	GO:0006357	regulation of transcription from RNA polymerase II promoter
6.05	9.49e-04	GO:0090329	regulation of DNA-dependent DNA replication
1.72	9.92e-04	GO:0009890	negative regulation of biosynthetic process
1.82	1.02e-03	GO:0051253	negative regulation of RNA metabolic process
3.52	1.03e-03	GO:0006473	protein acetylation
1.74	1.33e-03	GO:0006396	RNA processing
2.46	1.69e-03	GO:0016569	covalent chromatin modification
6.33	1.94e-03	GO:2000104	negative regulation of DNA-dependent DNA replication
4.22	2.24e-03	GO:0000819	sister chromatid segregation
2.37	2.91e-03	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.37	2.91e-03	GO:0000398	nuclear mRNA splicing, via spliceosome
2.92	3.13e-03	GO:0007059	chromosome segregation
3.56	3.19e-03	GO:0018394	peptidyl-lysine acetylation
2.43	3.29e-03	GO:0016570	histone modification
2.80	4.34e-03	GO:0031570	DNA integrity checkpoint
4.22	5.19e-03	GO:0000070	mitotic sister chromatid segregation
1.72	5.29e-03	GO:0010629	negative regulation of gene expression
2.31	5.48e-03	GO:0000375	RNA splicing, via transesterification reactions
6.33	7.09e-03	GO:0007062	sister chromatid cohesion
3.88	7.60e-03	GO:0007051	spindle organization
1.76	8.19e-03	GO:0045892	negative regulation of transcription, DNA-dependent
4.33	8.64e-03	GO:0008156	negative regulation of DNA replication
3.47	9.20e-03	GO:0016573	histone acetylation
1.53	1.03e-02	GO:0032774	RNA biosynthetic process
2.01	1.04e-02	GO:0008380	RNA splicing
1.93	1.07e-02	GO:0051301	cell division
3.42	1.17e-02	GO:0018393	internal peptidyl-lysine acetylation
3.05	1.17e-02	GO:0043543	protein acylation
6.00	1.25e-02	GO:0032201	telomere maintenance via semi-conservative replication
6.00	1.25e-02	GO:0051225	spindle assembly
3.26	1.31e-02	GO:0006302	double-strand break repair
2.43	1.39e-02	GO:0000226	microtubule cytoskeleton organization
3.31	1.85e-02	GO:0006475	internal protein amino acid acetylation
3.43	2.07e-02	GO:0000079	regulation of cyclin-dependent protein kinase activity
5.70	2.12e-02	GO:0000722	telomere maintenance via recombination
5.70	2.12e-02	GO:0006298	mismatch repair
3.12	2.47e-02	GO:0006338	chromatin remodeling
1.54	2.50e-02	GO:0006351	transcription, DNA-dependent
2.67	2.58e-02	GO:0007126	meiosis
2.67	2.58e-02	GO:0051327	M phase of meiotic cell cycle
1.14	2.88e-02	GO:0050794	regulation of cellular process
2.65	3.02e-02	GO:0051321	meiotic cell cycle
3.69	3.03e-02	GO:0000723	telomere maintenance
4.87	3.60e-02	GO:0006312	mitotic recombination
1.86	3.84e-02	GO:0007420	brain development
4.11	3.85e-02	GO:0051318	G1 phase
3.62	3.94e-02	GO:0032200	telomere organization
8.44	4.02e-02	GO:0002566	somatic diversification of immune receptors via somatic mutation
8.44	4.02e-02	GO:0016446	somatic hypermutation of immunoglobulin genes
2.08	4.45e-02	GO:0009314	response to radiation
2.90	4.45e-02	GO:0018205	peptidyl-lysine modification
4.35	4.68e-02	GO:0000724	double-strand break repair via homologous recombination
4.35	4.68e-02	GO:0000725	recombinational repair

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.60	1.61e-47	GO:0005634	nucleus
1.32	7.24e-43	GO:0043229	intracellular organelle
1.32	8.27e-43	GO:0043226	organelle
1.35	2.88e-40	GO:0043227	membrane-bounded organelle
1.35	3.73e-40	GO:0043231	intracellular membrane-bounded organelle
2.06	5.30e-39	GO:0044428	nuclear part
2.16	9.59e-38	GO:0031981	nuclear lumen
1.96	6.43e-34	GO:0070013	intracellular organelle lumen
1.23	1.02e-33	GO:0044424	intracellular part
1.93	6.04e-33	GO:0043233	organelle lumen
1.92	1.11e-32	GO:0031974	membrane-enclosed lumen
1.21	2.55e-32	GO:0005622	intracellular
1.49	1.33e-31	GO:0044446	intracellular organelle part
2.26	2.07e-30	GO:0005654	nucleoplasm
1.47	3.19e-30	GO:0044422	organelle part
3.05	7.87e-29	GO:0005694	chromosome
3.06	4.03e-24	GO:0044427	chromosomal part
3.48	7.44e-17	GO:0000785	chromatin
1.55	1.14e-14	GO:0043228	non-membrane-bounded organelle
1.55	1.14e-14	GO:0043232	intracellular non-membrane-bounded organelle
1.45	1.05e-13	GO:0032991	macromolecular complex
2.11	2.23e-12	GO:0044451	nucleoplasm part
3.14	1.97e-11	GO:0000228	nuclear chromosome
3.20	1.44e-09	GO:0044454	nuclear chromosome part
4.05	2.20e-09	GO:0032993	protein-DNA complex
1.05	1.87e-07	GO:0044464	cell part
1.05	1.94e-07	GO:0005623	cell
4.29	1.81e-06	GO:0000786	nucleosome
5.47	2.14e-06	GO:0005657	replication fork
1.34	3.96e-06	GO:0043234	protein complex
4.60	4.08e-05	GO:0000792	heterochromatin
3.24	3.95e-04	GO:0000790	nuclear chromatin
1.80	5.11e-04	GO:0005730	nucleolus
1.78	5.74e-04	GO:0030529	ribonucleoprotein complex
2.57	7.50e-04	GO:0000775	chromosome, centromeric region
5.75	9.88e-04	GO:0043596	nuclear replication fork
2.19	1.34e-03	GO:0016604	nuclear body
9.49	2.42e-03	GO:0042555	MCM complex
2.24	4.80e-03	GO:0005819	spindle
3.52	4.84e-03	GO:0034708	methyltransferase complex
3.52	4.84e-03	GO:0035097	histone methyltransferase complex
8.44	6.78e-03	GO:0035098	ESC/E(Z) complex
5.96	7.72e-03	GO:0030894	replisome
5.96	7.72e-03	GO:0043601	nuclear replisome
1.57	1.21e-02	GO:0015630	microtubule cytoskeleton
5.63	1.29e-02	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
2.35	1.30e-02	GO:0000793	condensed chromosome
4.37	1.84e-02	GO:0005720	nuclear heterochromatin
3.02	1.96e-02	GO:0000922	spindle pole
5.33	2.08e-02	GO:0031519	PcG protein complex
2.97	4.24e-02	GO:0000123	histone acetyltransferase complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.63	3.59e-25	GO:0003676	nucleic acid binding
1.70	1.15e-19	GO:0003677	DNA binding
1.13	1.36e-12	GO:0005488	binding
1.24	4.83e-12	GO:0005515	protein binding
2.67	6.47e-06	GO:0043566	structure-specific DNA binding
2.57	2.82e-05	GO:0003682	chromatin binding
1.61	3.99e-05	GO:0030528	transcription regulator activity
5.68	5.42e-05	GO:0034061	DNA polymerase activity
5.84	1.16e-04	GO:0003887	DNA-directed DNA polymerase activity
1.56	4.50e-04	GO:0001071	nucleic acid binding transcription factor activity
1.56	4.50e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
1.34	5.57e-04	GO:0000166	nucleotide binding
3.78	6.49e-04	GO:0003697	single-stranded DNA binding
3.56	8.17e-04	GO:0008094	DNA-dependent ATPase activity
2.63	1.07e-03	GO:0003690	double-stranded DNA binding
1.59	1.37e-03	GO:0003723	RNA binding
3.69	7.77e-03	GO:0003684	damaged DNA binding
1.90	1.24e-02	GO:0016564	transcription repressor activity
6.33	2.47e-02	GO:0030983	mismatched DNA binding