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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: PAX5.p2

Z-value: 3.199

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_61742111	8.835	NM_020828	ZFP28	zinc finger protein 28 homolog (mouse)
chr8_+_22513043	7.926	NM_001013842 NM_001198827 NM_173686	C8orf58	chromosome 8 open reading frame 58
chr3_+_133923758	6.308		NCRNA00119	non-protein coding RNA 119
chr4_-_7991992	6.103	NM_001134647 NM_198595	AFAP1	actin filament associated protein 1
chr3_-_133923992	5.980		NPHP3-ACAD11	NPHP3-ACAD11 read-through transcript
chr3_-_133923906	5.712	NM_153240	NPHP3	nephronophthisis 3 (adolescent)
chr9_+_96807107	5.500		C9orf3	chromosome 9 open reading frame 3
chr1_-_93919789	5.444	NM_003567	BCAR3	breast cancer anti-estrogen resistance 3
chr2_+_235525355	5.073	NM_014521	SH3BP4	SH3-domain binding protein 4
chr12_-_93568336	4.738	NM_020698	TMCC3	transmembrane and coiled-coil domain family 3
chr12_+_13044604	4.642		HTR7P1	5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
chr21_-_43671355	4.639	NM_173354	SIK1	salt-inducible kinase 1
chr21_-_45118037	4.624	NM_004339	PTTG1IP	pituitary tumor-transforming 1 interacting protein
chr13_-_105985313	4.555	NM_004093	EFNB2	ephrin-B2
chr21_+_45118353	4.544
chr20_-_23566325	4.526	NM_000099	CST3	cystatin C
chr21_+_45318861	4.457	NM_001112 NM_001160230 NM_015833 NM_015834	ADARB1	adenosine deaminase, RNA-specific, B1
chr13_-_43351825	4.100	NM_144974	CCDC122	coiled-coil domain containing 122
chrX_+_43399101	4.055		MAOA	monoamine oxidase A
chr13_-_20533629	3.935		LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)
chr1_-_223907283	3.885	NM_001008493 NM_018212	ENAH	enabled homolog (Drosophila)
chr21_-_45117989	3.734		PTTG1IP	pituitary tumor-transforming 1 interacting protein
chr5_+_96023926	3.724		CAST	calpastatin
chr10_+_171410	3.713		ZMYND11	zinc finger, MYND-type containing 11
chr21_-_45118026	3.698		PTTG1IP	pituitary tumor-transforming 1 interacting protein
chr14_-_52487558	3.618	NM_001134999 NM_001135000 NM_006832	FERMT2	fermitin family member 2
chr7_-_107883929	3.589	NM_001193582 NM_001193583 NM_001193584 NM_005010	NRCAM	neuronal cell adhesion molecule
chr14_-_52487386	3.585		FERMT2	fermitin family member 2
chr19_-_1518875	3.572	NM_001174118 NM_203304	MEX3D	mex-3 homolog D (C. elegans)
chr10_-_15250616	3.529	NM_004808	NMT2	N-myristoyltransferase 2
chr4_+_3264509	3.490		RGS12	regulator of G-protein signaling 12
chr21_-_45117960	3.445		PTTG1IP	pituitary tumor-transforming 1 interacting protein
chr17_-_78199384	3.437	NM_019613	WDR45L	WDR45-like
chr3_+_160964574	3.418		SCHIP1	schwannomin interacting protein 1
chr12_-_13044467	3.391	NM_015987	HEBP1	heme binding protein 1
chr13_+_43351968	3.355	NM_153218	C13orf31	chromosome 13 open reading frame 31
chr11_+_101485946	3.326	NM_001130145 NM_001195044 NM_006106	YAP1	Yes-associated protein 1
chr1_-_22136263	3.246	NM_005529	HSPG2	heparan sulfate proteoglycan 2
chr6_-_56816403	3.233		DST	dystonin
chr15_-_27901828	3.229	NM_003257 NM_175610	TJP1	tight junction protein 1 (zona occludens 1)
chr2_+_238265617	3.227		LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chr12_+_3056781	3.179	NM_001168320 NM_006675	TSPAN9	tetraspanin 9
chr4_-_177950658	3.159	NM_005429	VEGFC	vascular endothelial growth factor C
chr6_-_109911125	3.155	NM_001164313 NM_014797	ZBTB24	zinc finger and BTB domain containing 24
chr2_+_238265519	3.136	NM_001137551 NM_001137552 NM_001137553 NM_004735	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chr8_-_80842452	3.128	NM_001040708 NM_012258	HEY1	hairy/enhancer-of-split related with YRPW motif 1
chr14_+_99329198	3.090	NM_001008707 NM_004434	EML1	echinoderm microtubule associated protein like 1
chr18_+_12298242	3.071	NM_032525	TUBB6	tubulin, beta 6
chr18_+_12298236	3.029		TUBB6	tubulin, beta 6
chr14_-_99842519	2.970	NM_001039355	SLC25A29	solute carrier family 25, member 29
chr18_+_12298189	2.966		TUBB6	tubulin, beta 6
chr2_-_16710551	2.875	NM_030797	FAM49A	family with sequence similarity 49, member A
chrX_+_17665483	2.863	NM_001037535 NM_001037536 NM_001037540 NM_006746	SCML1	sex comb on midleg-like 1 (Drosophila)
chr1_+_15957832	2.856	NM_017556	FBLIM1	filamin binding LIM protein 1
chr2_+_233270275	2.854		GIGYF2	GRB10 interacting GYF protein 2
chr11_+_109468734	2.834		ZC3H12C	zinc finger CCCH-type containing 12C
chr5_+_14196287	2.806	NM_007118	TRIO	triple functional domain (PTPRF interacting)
chr18_+_7557313	2.796	NM_001105244 NM_002845	PTPRM	protein tyrosine phosphatase, receptor type, M
chr7_+_55054152	2.794	NM_005228 NM_201282 NM_201283 NM_201284	EGFR	epidermal growth factor receptor
chr5_-_77980097	2.754	NM_005779	LHFPL2	lipoma HMGIC fusion partner-like 2
chr21_+_32706615	2.743	NM_058187	C21orf63	chromosome 21 open reading frame 63
chr10_-_30064600	2.740	NM_003174	SVIL	supervillin
chr12_-_13044448	2.733		HEBP1	heme binding protein 1
chr2_+_233270241	2.725	NM_001103146 NM_001103147 NM_001103148 NM_015575	GIGYF2	GRB10 interacting GYF protein 2
chr4_-_102487649	2.719	NM_000944 NM_001130691 NM_001130692	PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr3_-_151171190	2.689	NM_002628 NM_053024	PFN2	profilin 2
chr10_-_126839000	2.669		CTBP2	C-terminal binding protein 2
chr6_-_3697244	2.664	NM_183373	C6orf145	chromosome 6 open reading frame 145
chr15_-_58477407	2.642	NM_001002857 NM_001002858 NM_001136015 NM_004039	ANXA2	annexin A2
chr6_+_3697328	2.639
chr10_-_105604942	2.613	NM_014631	SH3PXD2A	SH3 and PX domains 2A
chr21_+_45649429	2.596	NM_130445	COL18A1	collagen, type XVIII, alpha 1
chr10_+_124124083	2.595	NM_001001974	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr3_+_173240983	2.562	NM_001135095	FNDC3B	fibronectin type III domain containing 3B
chr6_+_3696224	2.561
chr19_-_36531958	2.560	NM_020856	TSHZ3	teashirt zinc finger homeobox 3
chr17_+_40565492	2.547	NM_001135704	ACBD4	acyl-CoA binding domain containing 4
chr10_-_126839056	2.544	NM_001329	CTBP2	C-terminal binding protein 2
chr7_+_55054416	2.510		EGFR	epidermal growth factor receptor
chr11_+_12652427	2.500	NM_021961	TEAD1	TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr19_+_8361260	2.478		RAB11B	RAB11B, member RAS oncogene family
chr4_-_170428564	2.469		SH3RF1	SH3 domain containing ring finger 1
chr1_+_9275542	2.453		SPSB1	splA/ryanodine receptor domain and SOCS box containing 1
chr19_+_8361243	2.445		RAB11B	RAB11B, member RAS oncogene family
chr6_-_150227063	2.444	NM_032832	LRP11	low density lipoprotein receptor-related protein 11
chr14_+_102128741	2.443		RCOR1	REST corepressor 1
chr2_+_233270286	2.440		GIGYF2	GRB10 interacting GYF protein 2
chr1_-_23683308	2.426	NM_001143778 NM_017707	ASAP3	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr6_+_17389752	2.425	NM_001143942	RBM24	RNA binding motif protein 24
chr6_-_165996031	2.419		LOC100132188	LP7097
chr15_+_37660568	2.416	NM_003246	THBS1	thrombospondin 1
chr13_-_109236897	2.413	NM_003749	IRS2	insulin receptor substrate 2
chr19_+_8361200	2.378	NM_004218	RAB11B	RAB11B, member RAS oncogene family
chr1_+_181259317	2.372
chr10_-_35143900	2.358	NM_001184785 NM_001184786 NM_001184787 NM_001184788 NM_001184789 NM_001184790 NM_001184791 NM_001184792 NM_001184793 NM_001184794 NM_019619	PARD3	par-3 partitioning defective 3 homolog (C. elegans)
chr12_-_13044314	2.357		HEBP1	heme binding protein 1
chr17_-_53387493	2.347		CUEDC1	CUE domain containing 1
chr15_+_97009194	2.342		IGF1R	insulin-like growth factor 1 receptor
chr1_-_23683214	2.337		ASAP3	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
chr4_-_170428681	2.332		SH3RF1	SH3 domain containing ring finger 1
chr12_-_41269679	2.327	NM_153026	PRICKLE1	prickle homolog 1 (Drosophila)
chr9_-_129371171	2.322	NM_022833	FAM129B	family with sequence similarity 129, member B
chr22_+_36632242	2.316	NM_033386	MICALL1	MICAL-like 1
chr4_+_86615275	2.312	NM_001025616	ARHGAP24	Rho GTPase activating protein 24
chr9_-_36391149	2.309	NM_194330	RNF38	ring finger protein 38
chr3_-_123716454	2.306		KPNA1	karyopherin alpha 1 (importin alpha 5)
chr8_+_26296439	2.305	NM_004331	BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr3_-_123716471	2.301	NM_002264	KPNA1	karyopherin alpha 1 (importin alpha 5)
chr5_+_96023627	2.299	NM_001042440	CAST	calpastatin
chr1_+_9275518	2.291	NM_025106	SPSB1	splA/ryanodine receptor domain and SOCS box containing 1
chr18_-_63334902	2.278	NM_032160	DSEL	dermatan sulfate epimerase-like
chr13_-_20533703	2.272	NM_014572	LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)
chr7_-_1465633	2.242	NM_182924	MICALL2	MICAL-like 2
chr7_+_115926855	2.241		CAV2	caveolin 2
chr9_-_129370954	2.220		FAM129B	family with sequence similarity 129, member B
chr8_+_22479115	2.214	NM_001018003	SORBS3	sorbin and SH3 domain containing 3
chr1_-_15723363	2.214	NM_001229 NM_032996	CASP9	caspase 9, apoptosis-related cysteine peptidase
chr12_+_26003218	2.211	NM_001164748 NM_007211	RASSF8	Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr6_-_109911015	2.202		ZBTB24	zinc finger and BTB domain containing 24
chr10_+_124124196	2.199		PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr21_+_41461962	2.180		BACE2	beta-site APP-cleaving enzyme 2
chr4_-_158111995	2.165	NM_016205	PDGFC	platelet derived growth factor C
chr21_+_45649719	2.165
chr8_+_25097983	2.152		DOCK5	dedicator of cytokinesis 5
chr2_+_241023908	2.132		GPC1	glypican 1
chr17_-_24068759	2.127	NM_001144942 NM_031934	RAB34	RAB34, member RAS oncogene family
chrX_-_106846253	2.126	NM_001015881	TSC22D3	TSC22 domain family, member 3
chr4_+_89147821	2.122	NM_000297	PKD2	polycystic kidney disease 2 (autosomal dominant)
chr11_+_35922106	2.121	NM_174902	LDLRAD3	low density lipoprotein receptor class A domain containing 3
chr4_-_53220073	2.114	NM_022832	USP46	ubiquitin specific peptidase 46
chr4_-_102487506	2.079		PPP3CA	protein phosphatase 3, catalytic subunit, alpha isozyme
chr14_+_54102518	2.068		LOC644925	hypothetical LOC644925
chr2_+_241023703	2.066	NM_002081	GPC1	glypican 1
chr12_+_2938703	2.053	NM_003213 NM_201441 NM_201443	TEAD4	TEA domain family member 4
chr12_-_105165805	2.052	NM_006825	CKAP4	cytoskeleton-associated protein 4
chr14_+_102128844	2.050	NM_015156	RCOR1	REST corepressor 1
chr1_+_78126787	2.037	NM_001172309 NM_144573	NEXN	nexilin (F actin binding protein)
chr10_+_134972902	2.016
chr3_+_23961739	2.012	NM_005126	NR1D2	nuclear receptor subfamily 1, group D, member 2
chr15_-_32118477	1.987	NM_020371	AVEN	apoptosis, caspase activation inhibitor
chr21_+_41461597	1.982	NM_012105 NM_138991 NM_138992	BACE2	beta-site APP-cleaving enzyme 2
chr11_+_12355600	1.976	NM_018222	PARVA	parvin, alpha
chr3_-_151171576	1.969		PFN2	profilin 2
chr11_+_109469296	1.966	NM_033390	ZC3H12C	zinc finger CCCH-type containing 12C
chr7_+_1536847	1.965	NM_002360	MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr7_-_525556	1.952		PDGFA	platelet-derived growth factor alpha polypeptide
chrX_-_135161185	1.914	NM_001173517 NM_024597	MAP7D3	MAP7 domain containing 3
chr3_+_151171755	1.910		LOC646903	hypothetical LOC646903
chr22_+_36286350	1.898	NM_152243	CDC42EP1	CDC42 effector protein (Rho GTPase binding) 1
chr1_-_109386112	1.898	NM_001142550 NM_001142551 NM_014969	WDR47	WD repeat domain 47
chr7_+_30140868	1.892	NM_152793	C7orf41	chromosome 7 open reading frame 41
chr17_-_1341599	1.887	NM_033375	MYO1C	myosin IC
chr2_-_45090025	1.887	NM_016932	SIX2	SIX homeobox 2
chr2_-_101134146	1.885	NM_001102426	TBC1D8	TBC1 domain family, member 8 (with GRAM domain)
chr5_+_17270781	1.882		BASP1	brain abundant, membrane attached signal protein 1
chr8_-_142080169	1.881	NM_005607 NM_153831	PTK2	PTK2 protein tyrosine kinase 2
chr17_-_21395483	1.880	NM_001113434	C17orf51	chromosome 17 open reading frame 51
chr10_+_129595349	1.874		PTPRE	protein tyrosine phosphatase, receptor type, E
chr4_-_37364327	1.869	NM_001085399 NM_001085400	RELL1	RELT-like 1
chr20_+_59260847	1.867	NM_001794	CDH4	cadherin 4, type 1, R-cadherin (retinal)
chr6_+_139055244	1.866		FLJ46906	hypothetical LOC441172
chr11_+_109805799	1.859	NM_004109	FDX1	ferredoxin 1
chr12_-_75796898	1.841	NM_001321	CSRP2	cysteine and glycine-rich protein 2
chr18_+_9126742	1.840	NM_001083625 NM_015208	ANKRD12	ankyrin repeat domain 12
chr2_-_11402150	1.828	NM_004850	ROCK2	Rho-associated, coiled-coil containing protein kinase 2
chr1_+_220857774	1.816	NM_198551	MIA3	melanoma inhibitory activity family, member 3
chr11_-_33678861	1.815	NM_001166692	C11orf91	chromosome 11 open reading frame 91
chr2_+_159533329	1.812	NM_001145909 NM_033394	TANC1	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr13_-_113916066	1.800		RASA3	RAS p21 protein activator 3
chr8_-_13034873	1.799		DLC1	deleted in liver cancer 1
chr9_+_98252200	1.798	NM_014282	HABP4	hyaluronan binding protein 4
chr8_-_145090045	1.797	NM_201382	PLEC	plectin
chr14_-_29466562	1.787	NM_002742	PRKD1	protein kinase D1
chr4_-_187881977	1.787	NM_005245	FAT1	FAT tumor suppressor homolog 1 (Drosophila)
chr2_+_241586927	1.785	NM_001080437	SNED1	sushi, nidogen and EGF-like domains 1
chr17_-_72218535	1.775	NM_001008528 NM_001008529 NM_198530	MXRA7	matrix-remodelling associated 7
chr5_+_76047536	1.775	NM_001992	F2R	coagulation factor II (thrombin) receptor
chr1_+_116320698	1.769		SLC22A15	solute carrier family 22, member 15
chr1_+_243200275	1.764		EFCAB2	EF-hand calcium binding domain 2
chr19_+_8361265	1.758		RAB11B	RAB11B, member RAS oncogene family
chr15_+_71763830	1.757		CD276	CD276 molecule
chr9_+_100907213	1.744		TGFBR1	transforming growth factor, beta receptor 1
chr2_-_158440587	1.737	NM_001111067	ACVR1	activin A receptor, type I
chr19_+_39664706	1.735	NM_001080436	WTIP	Wilms tumor 1 interacting protein
chr1_+_243200251	1.727	NM_001143943	EFCAB2	EF-hand calcium binding domain 2
chr14_-_102593384	1.726	NM_006035	CDC42BPB	CDC42 binding protein kinase beta (DMPK-like)
chr8_+_1759502	1.724	NM_014629	ARHGEF10	Rho guanine nucleotide exchange factor (GEF) 10
chr5_+_175725050	1.723	NM_173664	ARL10	ADP-ribosylation factor-like 10
chr4_-_86106567	1.710	NM_014991	WDFY3	WD repeat and FYVE domain containing 3
chr7_-_35044177	1.707	NM_015283	DPY19L1	dpy-19-like 1 (C. elegans)
chr15_+_71763742	1.702		CD276	CD276 molecule
chr17_+_16886491	1.698	NM_015134 NM_201274	MPRIP	myosin phosphatase Rho interacting protein
chr10_+_99463446	1.698	NM_031484	MARVELD1	MARVEL domain containing 1
chr7_+_32963486	1.693	NM_007270	FKBP9	FK506 binding protein 9, 63 kDa
chr22_-_41375323	1.688	NM_000398	CYB5R3	cytochrome b5 reductase 3
chr21_+_46226072	1.688	NM_001848	COL6A1	collagen, type VI, alpha 1
chr11_+_32068990	1.685	NM_002901	RCN1	reticulocalbin 1, EF-hand calcium binding domain
chr6_-_105734535	1.685	NM_022361	POPDC3	popeye domain containing 3
chr5_+_96023479	1.684	NM_001190442	CAST	calpastatin
chr2_+_9264360	1.672		ASAP2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.17	5.39e-25	GO:0050794	regulation of cellular process
1.15	1.13e-23	GO:0050789	regulation of biological process
1.14	4.58e-21	GO:0065007	biological regulation
1.09	7.60e-21	GO:0009987	cellular process
1.19	6.03e-17	GO:0044260	cellular macromolecule metabolic process
1.29	1.75e-15	GO:0048523	negative regulation of cellular process
1.31	5.67e-15	GO:0006464	protein modification process
1.14	7.39e-15	GO:0044237	cellular metabolic process
1.36	1.24e-14	GO:0009966	regulation of signal transduction
1.29	5.47e-14	GO:0043412	macromolecule modification
1.32	2.74e-13	GO:0023051	regulation of signaling
1.25	1.77e-12	GO:0048519	negative regulation of biological process
1.23	3.35e-12	GO:0048518	positive regulation of biological process
1.15	7.79e-12	GO:0043170	macromolecule metabolic process
1.20	9.54e-12	GO:0060255	regulation of macromolecule metabolic process
1.24	1.32e-11	GO:0048522	positive regulation of cellular process
1.19	6.50e-11	GO:0016043	cellular component organization
1.11	7.19e-11	GO:0008152	metabolic process
1.17	1.07e-10	GO:0019222	regulation of metabolic process
1.12	1.55e-10	GO:0044238	primary metabolic process
1.18	1.82e-10	GO:0080090	regulation of primary metabolic process
1.16	2.23e-10	GO:0051716	cellular response to stimulus
1.22	2.66e-10	GO:0044267	cellular protein metabolic process
1.18	3.30e-10	GO:0031323	regulation of cellular metabolic process
1.18	8.07e-10	GO:0071840	cellular component organization or biogenesis
1.44	2.98e-09	GO:0007167	enzyme linked receptor protein signaling pathway
1.18	4.87e-09	GO:0007165	signal transduction
1.24	5.06e-08	GO:0048583	regulation of response to stimulus
1.46	1.25e-07	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.15	1.69e-07	GO:0023052	signaling
1.19	2.45e-07	GO:0071842	cellular component organization at cellular level
1.50	5.54e-07	GO:0009968	negative regulation of signal transduction
1.18	9.93e-07	GO:0071841	cellular component organization or biogenesis at cellular level
1.35	1.90e-06	GO:0046907	intracellular transport
1.24	2.63e-06	GO:0009653	anatomical structure morphogenesis
1.32	4.14e-06	GO:0008219	cell death
1.32	5.12e-06	GO:0016265	death
1.29	5.21e-06	GO:0010646	regulation of cell communication
1.26	6.04e-06	GO:0051641	cellular localization
1.63	6.78e-06	GO:0048011	nerve growth factor receptor signaling pathway
1.28	8.48e-06	GO:0051246	regulation of protein metabolic process
1.32	9.14e-06	GO:0051128	regulation of cellular component organization
1.34	1.02e-05	GO:0012501	programmed cell death
1.44	1.14e-05	GO:0010648	negative regulation of cell communication
1.23	1.47e-05	GO:0007399	nervous system development
1.41	1.84e-05	GO:0048585	negative regulation of response to stimulus
1.16	1.87e-05	GO:0019538	protein metabolic process
1.34	1.96e-05	GO:0006915	apoptosis
1.28	2.97e-05	GO:0006793	phosphorus metabolic process
1.28	2.97e-05	GO:0006796	phosphate metabolic process
1.43	3.07e-05	GO:0023057	negative regulation of signaling
1.13	3.27e-05	GO:0032502	developmental process
1.29	4.64e-05	GO:0022008	neurogenesis
1.28	4.90e-05	GO:0032268	regulation of cellular protein metabolic process
1.28	6.73e-05	GO:0032879	regulation of localization
1.24	7.69e-05	GO:0033036	macromolecule localization
1.31	7.69e-05	GO:0031399	regulation of protein modification process
1.16	7.73e-05	GO:0010468	regulation of gene expression
1.17	8.36e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.36	9.59e-05	GO:0000902	cell morphogenesis
1.16	1.03e-04	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.26	1.18e-04	GO:0051649	establishment of localization in cell
1.23	1.33e-04	GO:0035556	intracellular signal transduction
1.27	1.39e-04	GO:0009892	negative regulation of metabolic process
1.21	1.42e-04	GO:0006996	organelle organization
1.31	1.56e-04	GO:0016192	vesicle-mediated transport
1.15	1.59e-04	GO:0051171	regulation of nitrogen compound metabolic process
1.26	1.76e-04	GO:0007049	cell cycle
1.16	1.76e-04	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.74	2.10e-04	GO:0006470	protein dephosphorylation
1.16	2.24e-04	GO:0010556	regulation of macromolecule biosynthetic process
1.14	2.32e-04	GO:0048856	anatomical structure development
1.18	2.54e-04	GO:0048869	cellular developmental process
1.25	3.17e-04	GO:0008104	protein localization
1.28	3.22e-04	GO:0010605	negative regulation of macromolecule metabolic process
1.28	3.82e-04	GO:0031324	negative regulation of cellular metabolic process
1.33	4.29e-04	GO:0032989	cellular component morphogenesis
1.28	5.47e-04	GO:0033554	cellular response to stress
1.30	5.54e-04	GO:0006468	protein phosphorylation
1.16	5.83e-04	GO:0051252	regulation of RNA metabolic process
1.33	6.06e-04	GO:0001932	regulation of protein phosphorylation
1.25	6.10e-04	GO:0010941	regulation of cell death
1.32	6.62e-04	GO:0030030	cell projection organization
1.31	6.96e-04	GO:0045595	regulation of cell differentiation
1.13	7.56e-04	GO:0006807	nitrogen compound metabolic process
1.27	9.05e-04	GO:0048699	generation of neurons
1.15	1.02e-03	GO:0031326	regulation of cellular biosynthetic process
1.36	1.08e-03	GO:0032990	cell part morphogenesis
1.45	1.13e-03	GO:0060284	regulation of cell development
1.24	1.14e-03	GO:0043067	regulation of programmed cell death
1.27	1.34e-03	GO:0045184	establishment of protein localization
1.27	1.35e-03	GO:0015031	protein transport
1.36	1.40e-03	GO:0048858	cell projection morphogenesis
1.17	1.44e-03	GO:0030154	cell differentiation
1.14	1.69e-03	GO:0009889	regulation of biosynthetic process
1.30	1.74e-03	GO:0019220	regulation of phosphate metabolic process
1.30	1.74e-03	GO:0051174	regulation of phosphorus metabolic process
1.24	1.75e-03	GO:0042981	regulation of apoptosis
1.12	1.93e-03	GO:0007275	multicellular organismal development
1.65	2.13e-03	GO:0016311	dephosphorylation
1.16	2.30e-03	GO:0006355	regulation of transcription, DNA-dependent
1.13	2.33e-03	GO:0034641	cellular nitrogen compound metabolic process
1.34	3.15e-03	GO:0010942	positive regulation of cell death
1.34	4.91e-03	GO:0000904	cell morphogenesis involved in differentiation
1.29	5.09e-03	GO:0042325	regulation of phosphorylation
1.21	5.25e-03	GO:0009893	positive regulation of metabolic process
1.35	6.82e-03	GO:0048812	neuron projection morphogenesis
1.28	6.96e-03	GO:0009890	negative regulation of biosynthetic process
1.21	7.51e-03	GO:0031325	positive regulation of cellular metabolic process
1.15	7.59e-03	GO:0090304	nucleic acid metabolic process
1.13	8.08e-03	GO:0048731	system development
1.33	8.43e-03	GO:0043068	positive regulation of programmed cell death
1.24	8.99e-03	GO:0050793	regulation of developmental process
1.21	1.11e-02	GO:0010604	positive regulation of macromolecule metabolic process
1.48	1.16e-02	GO:0051129	negative regulation of cellular component organization
1.24	1.20e-02	GO:0048468	cell development
1.28	1.22e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
1.32	1.28e-02	GO:0043065	positive regulation of apoptosis
2.01	1.29e-02	GO:0006914	autophagy
1.33	1.38e-02	GO:0031175	neuron projection development
1.36	1.74e-02	GO:0007264	small GTPase mediated signal transduction
1.27	1.80e-02	GO:0031327	negative regulation of cellular biosynthetic process
1.77	1.94e-02	GO:0060828	regulation of canonical Wnt receptor signaling pathway
1.35	2.09e-02	GO:0007409	axonogenesis
1.97	2.38e-02	GO:0046519	sphingoid metabolic process
1.44	2.47e-02	GO:0030036	actin cytoskeleton organization
1.28	2.47e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20	2.89e-02	GO:0044248	cellular catabolic process
1.41	3.03e-02	GO:0051270	regulation of cellular component movement
1.28	3.06e-02	GO:0051172	negative regulation of nitrogen compound metabolic process
1.22	3.21e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.60	3.37e-02	GO:0030111	regulation of Wnt receptor signaling pathway
1.23	3.37e-02	GO:0006351	transcription, DNA-dependent
1.18	3.40e-02	GO:0065009	regulation of molecular function
1.34	3.58e-02	GO:0008285	negative regulation of cell proliferation
1.31	3.59e-02	GO:0051338	regulation of transferase activity
1.28	3.65e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.70	3.86e-02	GO:0006643	membrane lipid metabolic process
1.29	3.95e-02	GO:0051253	negative regulation of RNA metabolic process
1.25	4.07e-02	GO:2000026	regulation of multicellular organismal development
1.31	4.24e-02	GO:0007010	cytoskeleton organization
1.35	4.38e-02	GO:0051056	regulation of small GTPase mediated signal transduction
1.36	4.54e-02	GO:0018193	peptidyl-amino acid modification
1.28	4.56e-02	GO:0010629	negative regulation of gene expression
1.61	4.56e-02	GO:0010769	regulation of cell morphogenesis involved in differentiation
1.28	4.61e-02	GO:0048666	neuron development
1.30	4.67e-02	GO:0045892	negative regulation of transcription, DNA-dependent
1.31	4.80e-02	GO:0045859	regulation of protein kinase activity
1.30	4.90e-02	GO:0070727	cellular macromolecule localization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.12	7.00e-47	GO:0005622	intracellular
1.12	8.97e-45	GO:0044424	intracellular part
1.16	7.32e-36	GO:0005737	cytoplasm
1.14	4.95e-30	GO:0043227	membrane-bounded organelle
1.12	1.72e-29	GO:0043226	organelle
1.14	2.54e-29	GO:0043231	intracellular membrane-bounded organelle
1.12	1.24e-28	GO:0043229	intracellular organelle
1.17	1.09e-22	GO:0044444	cytoplasmic part
1.17	3.01e-19	GO:0005634	nucleus
1.26	4.17e-13	GO:0005829	cytosol
1.13	1.52e-10	GO:0044422	organelle part
1.13	2.83e-10	GO:0044446	intracellular organelle part
1.03	1.51e-09	GO:0044464	cell part
1.03	1.67e-09	GO:0005623	cell
1.82	3.55e-08	GO:0005912	adherens junction
1.24	1.19e-07	GO:0012505	endomembrane system
1.30	3.95e-07	GO:0005794	Golgi apparatus
1.72	7.42e-07	GO:0070161	anchoring junction
1.19	1.39e-06	GO:0031090	organelle membrane
1.62	2.46e-05	GO:0031252	cell leading edge
1.17	4.56e-05	GO:0044428	nuclear part
1.31	5.24e-05	GO:0015630	microtubule cytoskeleton
1.76	1.84e-04	GO:0030055	cell-substrate junction
1.79	2.04e-04	GO:0005925	focal adhesion
1.76	2.43e-04	GO:0005924	cell-substrate adherens junction
1.32	2.74e-04	GO:0044431	Golgi apparatus part
1.19	1.77e-03	GO:0005654	nucleoplasm
1.32	2.21e-03	GO:0000139	Golgi membrane
1.16	2.43e-03	GO:0031981	nuclear lumen
1.17	2.63e-03	GO:0005856	cytoskeleton
1.23	6.69e-03	GO:0031982	vesicle
1.34	1.01e-02	GO:0048471	perinuclear region of cytoplasm
1.37	1.58e-02	GO:0015629	actin cytoskeleton
1.13	1.75e-02	GO:0070013	intracellular organelle lumen
1.37	1.81e-02	GO:0005874	microtubule
1.22	2.27e-02	GO:0031410	cytoplasmic vesicle
1.12	2.67e-02	GO:0043233	organelle lumen
2.11	2.85e-02	GO:0042641	actomyosin
1.18	3.61e-02	GO:0005783	endoplasmic reticulum
1.12	3.74e-02	GO:0031974	membrane-enclosed lumen
1.85	3.77e-02	GO:0005793	ER-Golgi intermediate compartment
1.24	4.18e-02	GO:0030054	cell junction

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.15	7.62e-22	GO:0005515	protein binding
1.08	5.11e-21	GO:0005488	binding
1.22	1.45e-09	GO:0000166	nucleotide binding
1.35	5.58e-07	GO:0019899	enzyme binding
1.29	4.64e-06	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.43	6.46e-06	GO:0004674	protein serine/threonine kinase activity
1.19	8.25e-06	GO:0017076	purine nucleotide binding
1.19	1.33e-05	GO:0032553	ribonucleotide binding
1.19	1.33e-05	GO:0032555	purine ribonucleotide binding
1.19	2.47e-05	GO:0035639	purine ribonucleoside triphosphate binding
1.40	3.04e-05	GO:0019904	protein domain specific binding
1.30	3.20e-05	GO:0016301	kinase activity
1.21	4.15e-05	GO:0030554	adenyl nucleotide binding
1.27	4.60e-05	GO:0030234	enzyme regulator activity
1.20	8.44e-05	GO:0032559	adenyl ribonucleotide binding
1.37	1.12e-04	GO:0060589	nucleoside-triphosphatase regulator activity
1.30	1.30e-04	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.20	1.31e-04	GO:0005524	ATP binding
1.37	1.48e-04	GO:0030695	GTPase regulator activity
1.09	1.65e-04	GO:0003824	catalytic activity
1.63	2.14e-04	GO:0004721	phosphoprotein phosphatase activity
1.31	3.82e-04	GO:0004672	protein kinase activity
1.49	4.09e-04	GO:0016791	phosphatase activity
1.27	6.89e-04	GO:0042802	identical protein binding
1.46	8.82e-04	GO:0016881	acid-amino acid ligase activity
1.38	3.26e-03	GO:0042578	phosphoric ester hydrolase activity
1.22	3.38e-03	GO:0030528	transcription regulator activity
1.16	5.01e-03	GO:0016740	transferase activity
1.40	5.57e-03	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.65	5.86e-03	GO:0051020	GTPase binding
1.64	1.32e-02	GO:0017124	SH3 domain binding
1.68	1.34e-02	GO:0004725	protein tyrosine phosphatase activity
1.66	1.68e-02	GO:0031267	small GTPase binding
1.37	2.52e-02	GO:0005083	small GTPase regulator activity
1.30	2.78e-02	GO:0016874	ligase activity
1.72	2.94e-02	GO:0019199	transmembrane receptor protein kinase activity
1.27	3.17e-02	GO:0008092	cytoskeletal protein binding
1.97	3.46e-02	GO:0046332	SMAD binding
2.60	3.46e-02	GO:0005024	transforming growth factor beta receptor activity
1.67	3.56e-02	GO:0017016	Ras GTPase binding
2.49	4.38e-02	GO:0004675	transmembrane receptor protein serine/threonine kinase activity