Motif ID: MYBL2.p2

Z-value: 1.187


Transcription factors associated with MYBL2.p2:

Gene SymbolEntrez IDGene Name
MYBL2 4605 v-myb myeloblastosis viral oncogene homolog (avian)-like 2



Activity profile for motif MYBL2.p2.

activity profile for motif MYBL2.p2


Sorted Z-values histogram for motif MYBL2.p2

Sorted Z-values for motif MYBL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYBL2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_197173159 2.784 LOC100131234
familial acute myelogenous leukemia related factor
chr3_+_100840129 2.672 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr3_+_158637273 2.668 NM_002852
PTX3
pentraxin 3, long
chr2_-_198248828 2.199 NM_144629
RFTN2
raftlin family member 2
chrX_-_33139349 1.970 NM_004006
DMD
dystrophin
chr15_+_41597097 1.915 NM_002373
MAP1A
microtubule-associated protein 1A
chr17_-_15495534 1.877 TRIM16
tripartite motif containing 16
chr12_+_55201854 1.856 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr9_+_119506428 1.811 TLR4
toll-like receptor 4
chr3_-_15814678 1.797 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr11_-_85107569 1.781 NM_206929
SYTL2
synaptotagmin-like 2
chr9_+_119506446 1.778 TLR4
toll-like receptor 4
chr10_+_17310263 1.673 NM_003380
VIM
vimentin
chr15_+_65205107 1.666 NM_001145102
SMAD3
SMAD family member 3
chr2_-_189752575 1.641 NM_000393
COL5A2
collagen, type V, alpha 2
chr5_-_39460787 1.466 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr5_-_39460687 1.440 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr5_-_54317102 1.433 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr15_-_40537002 1.381 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr5_-_39461054 1.352 NM_001343
DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr15_+_55298908 1.315 NM_207040
TCF12
transcription factor 12
chr10_+_17310475 1.310 VIM
vimentin
chr11_-_85108030 1.294 NM_001162952
NM_206930
SYTL2

synaptotagmin-like 2

chr2_+_151922350 1.236 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr1_+_159943385 1.224 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr21_+_29439768 1.220 C21orf7
chromosome 21 open reading frame 7
chr19_-_13808101 1.220 LOC284454
hypothetical LOC284454
chr2_+_170074457 1.205 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr9_-_72219359 1.138 NM_001206
KLF9
Kruppel-like factor 9
chr12_-_69317441 1.129 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr5_-_94442941 1.112 MCTP1
multiple C2 domains, transmembrane 1
chr11_+_65024889 1.084 MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr5_-_94443300 1.061 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr8_-_17599438 1.054 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr5_+_40877053 1.036 NM_032587
CARD6
caspase recruitment domain family, member 6
chr9_-_72218098 0.977 KLF9
Kruppel-like factor 9
chr8_-_122722674 0.961 NM_005328
HAS2
hyaluronan synthase 2
chr12_-_48902692 0.926 NM_001113547
LIMA1
LIM domain and actin binding 1
chr2_-_227952249 0.925 NM_024795
TM4SF20
transmembrane 4 L six family member 20
chr4_+_120276386 0.909 NM_016599
MYOZ2
myozenin 2
chr10_-_106088151 0.901 ITPRIP
inositol 1,4,5-triphosphate receptor interacting protein
chr1_-_208046011 0.897 NM_006147
IRF6
interferon regulatory factor 6
chr1_+_84539876 0.897 NM_001134663
SAMD13
sterile alpha motif domain containing 13
chr14_+_57964148 0.896


chr11_-_106941633 0.888 NM_138775
ALKBH8
alkB, alkylation repair homolog 8 (E. coli)
chr7_+_120416103 0.884 C7orf58
chromosome 7 open reading frame 58
chr9_+_119506274 0.884 NM_138554
TLR4
toll-like receptor 4
chr1_+_168898898 0.879 PRRX1
paired related homeobox 1
chr9_+_18464090 0.866 NM_001040272
NM_052866
ADAMTSL1

ADAMTS-like 1

chr16_+_14187965 0.862 MKL2
MKL/myocardin-like 2
chr10_-_95231933 0.851 NM_013451
NM_133337
MYOF

myoferlin

chrX_-_10548458 0.847 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chrX_-_19598912 0.845 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chrX_+_74410774 0.782


chr8_-_95343696 0.780 GEM
GTP binding protein overexpressed in skeletal muscle
chr11_-_124048808 0.777 NM_170601
SIAE
sialic acid acetylesterase
chr6_+_153060722 0.769 NM_025107
MYCT1
myc target 1
chr12_+_32578513 0.760 FGD4
FYVE, RhoGEF and PH domain containing 4
chr12_-_26169074 0.758 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr5_-_159778621 0.752 NM_006425
SLU7
SLU7 splicing factor homolog (S. cerevisiae)
chr1_+_208472817 0.748 NM_019605
SERTAD4
SERTA domain containing 4
chr4_+_3341521 0.746 NM_198227
RGS12
regulator of G-protein signaling 12
chr1_+_143807748 0.743 NM_004892
SEC22B
SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
chr5_-_90645974 0.713 LOC100505994
hypothetical LOC100505994
chrX_-_77801480 0.710 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr10_+_44726635 0.702 NM_001123376
TMEM72
transmembrane protein 72
chr3_-_113841967 0.681 CCDC80
coiled-coil domain containing 80
chr7_+_104539548 0.681 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr12_+_76749199 0.675 NM_014903
NAV3
neuron navigator 3
chr4_-_74307637 0.673 ANKRD17
ankyrin repeat domain 17
chr21_+_36429079 0.667 NM_001236
CBR3
carbonyl reductase 3
chr3_-_113495763 0.666 NM_183061
SLC9A10
solute carrier family 9, member 10
chr7_+_93388951 0.663 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr13_+_100902942 0.662 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr3_+_160964574 0.662 SCHIP1
schwannomin interacting protein 1
chr1_+_216585298 0.650 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr7_-_13997574 0.639 NM_001163148
ETV1
ets variant 1
chr3_-_113841448 0.631 CCDC80
coiled-coil domain containing 80
chr8_+_107807415 0.619 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr3_+_142569988 0.617 ZBTB38
zinc finger and BTB domain containing 38
chr13_+_110565587 0.616 NM_001113511
NM_001113512
NM_145735
ARHGEF7


Rho guanine nucleotide exchange factor (GEF) 7


chr6_-_152744022 0.612 SYNE1
spectrin repeat containing, nuclear envelope 1
chr3_-_113841941 0.598 CCDC80
coiled-coil domain containing 80
chr3_-_115960807 0.598 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr11_+_124048949 0.595 NM_017425
SPA17
sperm autoantigenic protein 17
chr2_+_230989114 0.592 NM_001080391
NM_003113
SP100

SP100 nuclear antigen

chr5_+_36642424 0.588 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_-_88086559 0.582 PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr1_-_171838802 0.580 NM_178527
SLC9A11
solute carrier family 9, member 11
chr1_-_21373816 0.579 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr3_-_113842133 0.575 CCDC80
coiled-coil domain containing 80
chr19_+_24061717 0.564 NM_203282
ZNF254
zinc finger protein 254
chr10_-_69762654 0.562 NM_001033083
NM_022129
PBLD

phenazine biosynthesis-like protein domain containing

chr1_-_153209625 0.562 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chr7_+_120416680 0.560 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr9_+_117955890 0.560 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr20_-_48686832 0.551 NM_080829
FAM65C
family with sequence similarity 65, member C
chr3_-_113842652 0.546 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr1_-_143786993 0.543 NM_022359
PDE4DIP
phosphodiesterase 4D interacting protein
chr8_-_95343716 0.539 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr15_+_47502666 0.537 NM_002009
FGF7
fibroblast growth factor 7
chr17_+_7753428 0.533 CHD3
chromodomain helicase DNA binding protein 3
chr1_+_15145001 0.532 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr3_+_29297806 0.525 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr9_-_94338072 0.520 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr5_-_58607673 0.514 NM_001197220
PDE4D
phosphodiesterase 4D, cAMP-specific
chr9_-_116190038 0.514 AKNA
AT-hook transcription factor
chr2_-_40510923 0.514 NM_001112800
NM_001112801
NM_021097
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr3_-_113842553 0.509 CCDC80
coiled-coil domain containing 80
chr11_-_111287657 0.506 NM_001885
CRYAB
crystallin, alpha B
chr6_-_112186977 0.504 NM_153048
FYN
FYN oncogene related to SRC, FGR, YES
chr4_-_122357104 0.503 NM_001128843
TNIP3
TNFAIP3 interacting protein 3
chr6_-_111995213 0.500 NM_001164283
TRAF3IP2
TRAF3 interacting protein 2
chr5_+_162862808 0.499 NM_182796
MAT2B
methionine adenosyltransferase II, beta
chr1_+_99884018 0.499 NM_017734
PALMD
palmdelphin
chr11_-_64269501 0.490 NM_153819
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr10_-_32707549 0.486 EPC1
enhancer of polycomb homolog 1 (Drosophila)
chr12_-_74765004 0.480 NM_004537
NM_139207
NAP1L1

nucleosome assembly protein 1-like 1

chr2_+_33555182 0.477 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr2_+_230989150 0.470 SP100
SP100 nuclear antigen
chr11_+_64950074 0.466 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr1_+_172060563 0.464 DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr8_-_10550026 0.459 NM_178857
RP1L1
retinitis pigmentosa 1-like 1
chr12_-_74764677 0.444 NAP1L1
nucleosome assembly protein 1-like 1
chr19_+_53520632 0.443 EMP3
epithelial membrane protein 3
chr15_+_89212888 0.440 NM_002569
FURIN
furin (paired basic amino acid cleaving enzyme)
chr1_+_172060440 0.437 DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr2_-_134042500 0.426 NM_207363
NM_207481
NCKAP5

NCK-associated protein 5

chr2_+_64540843 0.426 HSPC159
galectin-related protein
chr1_-_93030538 0.425 NM_005665
EVI5
ecotropic viral integration site 5
chr2_+_230989177 0.416 SP100
SP100 nuclear antigen
chr4_+_146820805 0.415 NM_001080531
C4orf51
chromosome 4 open reading frame 51
chr19_+_53520439 0.415 NM_001425
EMP3
epithelial membrane protein 3
chr22_-_35914200 0.413 NM_031910
NM_182486
C1QTNF6

C1q and tumor necrosis factor related protein 6

chr1_-_149047329 0.412 NM_000396
CTSK
cathepsin K
chr1_+_26358097 0.412 NM_024869
GRRP1
glycine/arginine rich protein 1
chr3_+_182900081 0.410 SOX2OT
SOX2 overlapping transcript (non-protein coding)
chr1_-_110735158 0.410 NM_004696
SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr5_+_112101454 0.409 NM_000038
NM_001127510
APC

adenomatous polyposis coli

chr12_+_121233615 0.387 NM_001098519
LRRC43
leucine rich repeat containing 43
chr17_+_39990124 0.387 NM_001466
FZD2
frizzled homolog 2 (Drosophila)
chr5_+_155686750 0.387 SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr1_+_143326315 0.386 NM_001037675
NBPF10
NBPF9
NBPF8
neuroblastoma breakpoint family, member 10
neuroblastoma breakpoint family, member 9
neuroblastoma breakpoint family, member 8
chr3_-_127810087 0.386 NM_001039783
TXNRD3IT1
thioredoxin reductase 3 intronic transcript 1
chr1_-_115102084 0.379 CSDE1
cold shock domain containing E1, RNA-binding
chr11_-_10487212 0.377 NM_001190702
MTRNR2L8
MT-RNR2-like 8
chr22_+_38903825 0.375 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr1_+_146843980 0.373 NM_001102663
NBPF15
NBPF8
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 8
neuroblastoma breakpoint family, member 16
chr7_-_81237162 0.371 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr6_-_112033775 0.370 TRAF3IP2
TRAF3 interacting protein 2
chr12_-_15005761 0.369 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr12_+_7039453 0.367


chr1_-_158521491 0.359 PEX19
peroxisomal biogenesis factor 19
chr2_+_84597087 0.359 NM_001370
DNAH6
dynein, axonemal, heavy chain 6
chr15_-_56093477 0.358 NM_170697
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr2_+_127130209 0.347 GYPC
glycophorin C (Gerbich blood group)
chr1_-_151788341 0.347 NM_002960
S100A3
S100 calcium binding protein A3
chr1_-_115102106 0.344 CSDE1
cold shock domain containing E1, RNA-binding
chr21_-_29179482 0.343 NM_013240
NM_182749
N6AMT1

N-6 adenine-specific DNA methyltransferase 1 (putative)

chr3_+_137167153 0.342 NM_001190447
NM_002718
PPP2R3A

protein phosphatase 2, regulatory subunit B'', alpha

chr19_+_10392128 0.341 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr11_-_35503720 0.341 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr1_-_115102109 0.340 CSDE1
cold shock domain containing E1, RNA-binding
chr6_-_112033752 0.339 TRAF3IP2
TRAF3 interacting protein 2
chr3_-_113842350 0.337 CCDC80
coiled-coil domain containing 80
chr3_-_113842255 0.335 CCDC80
coiled-coil domain containing 80
chr17_-_45619038 0.334 COL1A1
collagen, type I, alpha 1
chr12_-_6321417 0.330 NM_001065
TNFRSF1A
tumor necrosis factor receptor superfamily, member 1A
chr1_-_158521547 0.330 NM_001193644
NM_002857
PEX19

peroxisomal biogenesis factor 19

chr1_-_115102124 0.330 CSDE1
cold shock domain containing E1, RNA-binding
chr14_-_22358752 0.330 NM_001126106
SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr11_-_71469382 0.329 NUMA1
nuclear mitotic apparatus protein 1
chr16_+_80086454 0.328 NM_030629
CMIP
c-Maf-inducing protein
chr10_+_35524835 0.328 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr6_-_117853710 0.326 NM_002944
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr14_+_57964462 0.325 NM_014749
KIAA0586
KIAA0586
chr1_-_191422346 0.324 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr1_+_172060389 0.322 NM_018122
DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr13_-_74799898 0.320 TBC1D4
TBC1 domain family, member 4
chr10_+_104525877 0.319 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr11_-_85103438 0.318 NM_032379
SYTL2
synaptotagmin-like 2
chr21_-_26345294 0.318


chr6_+_136214495 0.317 NM_018945
PDE7B
phosphodiesterase 7B
chr22_-_37211467 0.316 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr2_+_127130148 0.315 NM_002101
NM_016815
GYPC

glycophorin C (Gerbich blood group)

chr7_+_28692122 0.314 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr11_+_128068982 0.314 NM_002017
FLI1
Friend leukemia virus integration 1
chr1_-_85816520 0.313 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr9_-_14388981 0.311 NM_001190738
NFIB
nuclear factor I/B
chr14_+_101345878 0.309 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr4_-_38710376 0.309 NM_024943
TMEM156
transmembrane protein 156
chr1_-_172059780 0.308 NM_001171182
CENPL
centromere protein L
chr6_+_45404031 0.302 NM_001015051
NM_001024630
RUNX2

runt-related transcription factor 2

chr9_+_115396020 0.300 NM_144489
RGS3
regulator of G-protein signaling 3
chr3_-_113841200 0.300 CCDC80
coiled-coil domain containing 80
chr22_+_36401558 0.300 NM_002305
LGALS1
lectin, galactoside-binding, soluble, 1
chr3_-_50583425 0.300 NM_001171741
C3orf18
chromosome 3 open reading frame 18
chr4_+_120167264 0.298 SYNPO2
synaptopodin 2
chrX_+_74410618 0.298 NM_145052
UPRT
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr8_-_93144039 0.297



Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

enrichment   p-value GO term description
10.57 2.60e-02 GO:0004745 retinol dehydrogenase activity