Motif ID: HNF1A.p2

Z-value: 9.830


Transcription factors associated with HNF1A.p2:

Gene SymbolEntrez IDGene Name
HNF1A 6927 HNF1 homeobox A



Activity profile for motif HNF1A.p2.

activity profile for motif HNF1A.p2


Sorted Z-values histogram for motif HNF1A.p2

Sorted Z-values for motif HNF1A.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HNF1A.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_24491498 44.987 NM_001195610
DCDC2
doublecortin domain containing 2
chr12_-_15757114 33.578 EPS8
epidermal growth factor receptor pathway substrate 8
chr8_-_17797127 28.663 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chrX_-_105169370 27.741 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr17_-_61655915 27.259 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr7_-_44547382 26.244 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr7_+_45894480 25.804 NM_000596
IGFBP1
insulin-like growth factor binding protein 1
chr4_-_977163 25.623 NM_022042
NM_134425
NM_213613
SLC26A1


solute carrier family 26 (sulfate transporter), member 1


chr20_+_41621119 25.289 SGK2
serum/glucocorticoid regulated kinase 2
chr4_-_69852090 24.840 NM_024743
UGT2A3
UDP glucuronosyltransferase 2 family, polypeptide A3
chr20_+_41621079 24.721 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr14_-_93829309 24.111 SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr7_-_47545717 23.970 NM_022748
TNS3
tensin 3
chr10_+_114144512 23.968 ACSL5
acyl-CoA synthetase long-chain family member 5
chr16_-_86527608 23.781 NM_001739
CA5A
carbonic anhydrase VA, mitochondrial
chr14_-_93829113 23.645 NM_016186
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr19_+_11211282 23.478 NM_018687
LOC55908
hepatocellular carcinoma-associated gene TD26
chr14_+_20226762 23.361 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr14_-_93829347 23.331 NM_001100607
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr4_+_74520796 22.753 NM_001134
AFP
alpha-fetoprotein
chr17_+_71065478 22.266 LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr14_-_93924663 21.935 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr4_-_155731288 21.210 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr1_+_17779528 21.187 NM_001011722
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr20_+_42417752 20.767 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chr1_+_48460943 20.511 NM_001011547
NM_001135181
SLC5A9

solute carrier family 5 (sodium/glucose cotransporter), member 9

chr4_-_186970366 20.247 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr14_-_93924873 19.904 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr17_+_4638966 19.766 NM_001014985
GLTPD2
glycolipid transfer protein domain containing 2
chr2_+_27573206 19.734 NM_001486
GCKR
glucokinase (hexokinase 4) regulator
chr6_+_64289585 19.556 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr17_+_71154240 18.497 NM_001162997
LOC100130933
hypothetical protein LOC100130933
chr14_-_93859394 18.339 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr7_-_50600536 18.256 NM_001082971
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr20_+_42463419 17.942 HNF4A
hepatocyte nuclear factor 4, alpha
chr20_+_42417502 17.778 HNF4A
hepatocyte nuclear factor 4, alpha
chr14_+_38772870 17.640 NM_054024
MIA2
melanoma inhibitory activity 2
chr10_+_101532450 17.148 NM_000392
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr6_+_31731667 16.756 APOM
apolipoprotein M
chr6_+_31731647 16.425 NM_019101
APOM
apolipoprotein M
chr9_-_122852356 16.014 NM_001735
C5
complement component 5
chr17_+_38306339 15.803 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr6_-_116488458 15.767 NM_002031
FRK
fyn-related kinase
chr8_+_76482661 15.750 HNF4G
hepatocyte nuclear factor 4, gamma
chr4_+_74566325 15.518 NM_001133
AFM
afamin
chr11_+_46697345 15.431 F2
coagulation factor II (thrombin)
chr4_+_74488947 15.316 ALB
albumin
chr20_+_42463387 15.142 HNF4A
hepatocyte nuclear factor 4, alpha
chr4_-_110942576 15.083 CFI
complement factor I
chr20_+_42463350 15.038 HNF4A
hepatocyte nuclear factor 4, alpha
chr2_-_88208650 15.008 NM_001443
FABP1
fatty acid binding protein 1, liver
chr21_-_46399900 14.790 NM_006657
NM_206965
FTCD

formiminotransferase cyclodeaminase

chr11_+_46697335 14.683 F2
coagulation factor II (thrombin)
chr19_-_40995606 14.551 PRODH2
proline dehydrogenase (oxidase) 2
chr19_-_53081326 14.462 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr11_+_46697312 14.285 NM_000506
F2
coagulation factor II (thrombin)
chr4_+_74488910 13.952 ALB
albumin
chr4_-_100359353 13.943 NM_000672
NM_001102470
ADH6

alcohol dehydrogenase 6 (class V)

chr1_+_93830106 13.776 LOC100129046
hypothetical LOC100129046
chr19_-_53081383 13.774 NM_003167
SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr6_-_26038817 13.685 NM_005835
SLC17A2
solute carrier family 17 (sodium phosphate), member 2
chr20_+_42463279 13.682 NM_000457
NM_178849
NM_178850
HNF4A


hepatocyte nuclear factor 4, alpha


chr15_-_88150823 13.587 ANPEP
alanyl (membrane) aminopeptidase
chr6_+_167624792 13.434 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr12_+_54910767 13.303 NM_001135195
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr4_+_74488835 13.269 NM_000477
ALB
albumin
chr5_+_175908948 13.249 NM_017675
CDHR2
cadherin-related family member 2
chr10_-_52315436 12.889 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr4_-_110942783 12.835 NM_000204
CFI
complement factor I
chr16_+_21152516 12.639 NM_145865
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr10_-_52315390 12.540 A1CF
APOBEC1 complementation factor
chrX_+_70351773 12.503 NM_001097642
GJB1
gap junction protein, beta 1, 32kDa
chr19_-_40995564 12.493 PRODH2
proline dehydrogenase (oxidase) 2
chrX_+_70351812 12.436 GJB1
gap junction protein, beta 1, 32kDa
chr10_+_101532544 11.875 ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr1_+_93830169 11.750 LOC100129046
hypothetical LOC100129046
chr14_+_94097513 11.679 NM_006215
SERPINA4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
chr17_-_202557 11.665 RPH3AL
rabphilin 3A-like (without C2 domains)
chr4_+_187424111 11.366 NM_000128
F11
coagulation factor XI
chr4_+_3413489 11.340 NM_001528
HGFAC
HGF activator
chr17_+_1586034 11.141 WDR81
WD repeat domain 81
chr4_+_3413457 10.823 HGFAC
HGF activator
chr15_+_56511466 10.314 NM_000236
LIPC
lipase, hepatic
chr17_+_1592879 10.128 NM_000934
NM_001165921
SERPINF2

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2

chr8_+_21967008 10.002 NM_001114137
EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr5_+_73145098 9.957 RGNEF
190 kDa guanine nucleotide exchange factor
chr4_+_69996780 9.863 NM_001074
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr1_+_205328834 9.789 NM_001017365
NM_001017366
C4BPB

complement component 4 binding protein, beta

chr10_+_5126613 9.487 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr11_-_117200618 9.330 NM_001127489
NM_001680
FXYD2

FXYD domain containing ion transport regulator 2

chr1_+_205344200 9.177 NM_000715
C4BPA
complement component 4 binding protein, alpha
chr16_-_46826588 9.166 NM_032583
NM_145186
ABCC11

ATP-binding cassette, sub-family C (CFTR/MRP), member 11

chr10_+_5126589 9.092 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr10_+_5126556 9.050 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr17_-_202617 9.008 NM_001190411
NM_001190412
NM_001190413
NM_006987
RPH3AL



rabphilin 3A-like (without C2 domains)



chr1_-_202449659 8.866 NM_198447
GOLT1A
golgi transport 1A
chr17_+_1592893 8.673 SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr1_-_204455269 8.327 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr16_-_67943157 7.473 NM_144676
TMED6
transmembrane emp24 protein transport domain containing 6
chr12_+_119900677 7.135 HNF1A
HNF1 homeobox A
chr14_+_87560646 6.994 LOC283587
hypothetical protein LOC283587
chr11_+_64079665 6.640 NM_018484
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr4_+_74497998 6.466 ALB
albumin
chr5_+_176446425 6.449 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr5_-_138746840 6.359 SLC23A1
solute carrier family 23 (nucleobase transporters), member 1
chr5_-_138746917 6.294 NM_005847
NM_152685
SLC23A1

solute carrier family 23 (nucleobase transporters), member 1

chr6_+_31815703 6.266 NM_002441
NM_025259
NM_172165
NM_172166
MSH5-C6ORF26
MSH5



MSH5-C6orf26 read-through transcript
mutS homolog 5 (E. coli)



chr6_+_167456230 6.216 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr1_+_18680010 6.172 NM_152375
KLHDC7A
kelch domain containing 7A
chr18_+_27425727 5.962 NM_000371
TTR
transthyretin
chr4_+_74498042 5.916 ALB
albumin
chr17_+_1593040 5.638 NM_001165920
SERPINF2
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr13_-_40491405 5.496 ELF1
E74-like factor 1 (ets domain transcription factor)
chr4_+_187424336 5.312 F11
coagulation factor XI
chr2_+_62787534 5.054 NM_001142614
EHBP1
EH domain binding protein 1
chr6_+_161043214 4.984 NM_000301
NM_001168338
PLG

plasminogen

chr1_-_20014180 4.956 NM_019062
RNF186
ring finger protein 186
chr20_+_61841553 4.914 NM_020062
SLC2A4RG
SLC2A4 regulator
chr20_+_35406497 4.677 NM_005417
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr1_-_228916559 4.665 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr13_-_40491491 4.572 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr10_+_99334411 4.035 HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr19_+_50109416 4.026 APOC1
apolipoprotein C-I
chr2_+_101981888 3.984 NM_173343
IL1R2
interleukin 1 receptor, type II
chr19_-_63556632 3.977 NM_130786
A1BG
alpha-1-B glycoprotein
chrX_-_131375217 3.960 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr19_-_40996040 3.926 NM_021232
PRODH2
proline dehydrogenase (oxidase) 2
chr1_-_195302973 3.876 NM_001994
F13B
coagulation factor XIII, B polypeptide
chr20_-_43972061 3.828 PLTP
phospholipid transfer protein
chr7_-_156494741 3.723 NM_001165255
MNX1
motor neuron and pancreas homeobox 1
chr10_+_99334069 3.594 NM_001134670
NM_138413
HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr22_-_36836478 3.470 BAIAP2L2
BAI1-associated protein 2-like 2
chr4_+_155703581 3.431 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr11_-_118405288 3.415 NM_001164280
SLC37A4
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr14_-_57030227 3.371 NM_018168
C14orf105
chromosome 14 open reading frame 105
chr22_-_36836620 3.248 NM_025045
BAIAP2L2
BAI1-associated protein 2-like 2
chr16_+_88224175 3.246 DPEP1
dipeptidase 1 (renal)
chr4_+_74493918 3.198 ALB
albumin
chr2_-_168812132 3.154 NM_013233
STK39
serine threonine kinase 39
chr8_-_124818754 3.149 NM_001003954
NM_004306
ANXA13

annexin A13

chr3_+_63928459 3.144 NM_001128149
ATXN7
ataxin 7
chr4_-_159312973 3.054 FAM198B
family with sequence similarity 198, member B
chr12_+_119900931 3.051 NM_000545
HNF1A
HNF1 homeobox A
chr22_-_41685827 2.916 NM_001184971
PACSIN2
protein kinase C and casein kinase substrate in neurons 2
chr3_+_150675117 2.876 NM_004617
TM4SF4
transmembrane 4 L six family member 4
chr17_-_53335748 2.813 NM_017949
CUEDC1
CUE domain containing 1
chr7_+_99263571 2.682 NM_022820
NM_057095
NM_057096
CYP3A43


cytochrome P450, family 3, subfamily A, polypeptide 43


chr16_+_30118036 2.660 NM_001017390
NM_177552
SULT1A4
SULT1A3
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr20_-_17589122 2.645 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chr1_-_36562341 2.426 NM_018166
FAM176B
family with sequence similarity 176, member B
chr14_+_38805251 2.339 NM_203356
CTAGE5
CTAGE family, member 5
chr4_-_159313167 2.289 NM_016613
FAM198B
family with sequence similarity 198, member B
chr16_+_56286212 2.241 NM_032269
CCDC135
coiled-coil domain containing 135
chr16_-_56389176 2.193 NM_001130099
KIFC3
kinesin family member C3
chr1_-_228916486 2.189 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr22_+_43476710 2.170 NM_181333
PRR5
proline rich 5 (renal)
chr16_+_88224276 2.160 DPEP1
dipeptidase 1 (renal)
chr7_+_94953148 2.085 NM_016116
NM_145872
ASB4

ankyrin repeat and SOCS box containing 4

chr11_+_551449 2.083 NM_001143994
NM_003475
RASSF7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr13_+_96672705 2.077 MBNL2
muscleblind-like 2 (Drosophila)
chr4_+_124537334 2.073 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr20_+_55569542 2.046 NM_002591
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr19_-_38052481 2.017 NM_001126335
NM_014270
SLC7A9

solute carrier family 7 (cationic amino acid transporter, y+ system), member 9

chr16_+_20682812 2.013 NM_005622
NM_202000
ACSM3

acyl-CoA synthetase medium-chain family member 3

chr3_+_150675169 1.982 TM4SF4
transmembrane 4 L six family member 4
chr12_-_23993830 1.968 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr9_-_116305273 1.931 NM_001083885
DFNB31
deafness, autosomal recessive 31
chr1_-_228916470 1.914 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chrX_-_107569256 1.885 NM_001847
COL4A6
collagen, type IV, alpha 6
chr11_-_8695974 1.875 ST5
suppression of tumorigenicity 5
chr19_-_44135166 1.860 NM_148169
FBXO17
F-box protein 17
chr12_-_69838045 1.815 NM_004616
TSPAN8
tetraspanin 8
chr18_-_44723116 1.781 NM_001190823
SMAD7
SMAD family member 7
chr10_-_101680645 1.749 DNMBP
dynamin binding protein
chr21_-_42219849 1.700 NM_199050
C2CD2
C2 calcium-dependent domain containing 2
chr9_-_115901157 1.697 NM_138424
KIF12
kinesin family member 12
chr6_+_158653679 1.621 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr13_-_99983945 1.621 NM_033110
A2LD1
AIG2-like domain 1
chr6_+_131936057 1.616 NM_000045
ARG1
arginase, liver
chr17_-_36469869 1.614 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr1_-_151852128 1.562 NM_080388
S100A16
S100 calcium binding protein A16
chr6_-_25982418 1.551 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3

chr5_-_78318112 1.525 NM_000046
ARSB
arylsulfatase B
chr12_-_122322117 1.435 NM_004642
CDK2AP1
cyclin-dependent kinase 2 associated protein 1
chr7_-_27133163 1.405 NM_153631
HOXA3
homeobox A3
chr17_+_65009986 1.387 MAP2K6
mitogen-activated protein kinase kinase 6
chr7_-_5428043 1.325 TNRC18
trinucleotide repeat containing 18
chr22_+_43476755 1.322 NM_181334
PRR5-ARHGAP8
PRR5
PRR5-ARHGAP8 readthrough
proline rich 5 (renal)
chr2_-_162638790 1.319 DPP4
dipeptidyl-peptidase 4
chr12_-_12182641 1.208 LRP6
low density lipoprotein receptor-related protein 6
chr4_+_154345039 1.171 NM_015271
TRIM2
tripartite motif containing 2
chr17_+_56832255 1.168 TBX2
T-box 2
chr2_+_108271526 1.118 NM_001056
NM_176825
SULT1C2

sulfotransferase family, cytosolic, 1C, member 2

chr7_+_129913271 1.061 NM_177524
MEST
mesoderm specific transcript homolog (mouse)
chr15_+_57691382 1.057 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr1_+_144149794 1.051 NM_006472
TXNIP
thioredoxin interacting protein
chrX_+_107569671 1.050 NM_000495
NM_033380
COL4A5

collagen, type IV, alpha 5

chr4_-_70115037 1.038 NM_001073
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr6_-_31789824 1.037


chr17_+_77910411 0.979 NM_207459
TEX19
testis expressed 19

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
3.50 4.51e-04 GO:0071702 organic substance transport
2.80 6.79e-04 GO:0006082 organic acid metabolic process
26.08 8.76e-04 GO:0051917 regulation of fibrinolysis
1.85 1.79e-03 GO:0042221 response to chemical stimulus
4.27 3.10e-03 GO:0008202 steroid metabolic process
10.96 3.50e-03 GO:0030301 cholesterol transport
10.69 4.17e-03 GO:0015918 sterol transport
13.42 5.31e-03 GO:0030195 negative regulation of blood coagulation
8.35 5.71e-03 GO:0033500 carbohydrate homeostasis
8.35 5.71e-03 GO:0042593 glucose homeostasis
5.56 5.75e-03 GO:0030162 regulation of proteolysis
12.95 6.61e-03 GO:0050819 negative regulation of coagulation
27.82 9.14e-03 GO:0051918 negative regulation of fibrinolysis
16.48 1.17e-02 GO:0034381 plasma lipoprotein particle clearance
7.59 1.18e-02 GO:0055088 lipid homeostasis
9.13 1.24e-02 GO:0033993 response to lipid
46.95 1.94e-02 GO:0015712 hexose phosphate transport
46.95 1.94e-02 GO:0015760 glucose-6-phosphate transport
10.73 2.08e-02 GO:0097006 regulation of plasma lipoprotein particle levels
22.76 2.34e-02 GO:0046415 urate metabolic process
4.72 2.73e-02 GO:0006869 lipid transport
10.15 2.91e-02 GO:0008206 bile acid metabolic process
2.22 3.10e-02 GO:0006629 lipid metabolic process
2.47 3.62e-02 GO:0019752 carboxylic acid metabolic process
2.47 3.62e-02 GO:0043436 oxoacid metabolic process
9.63 3.97e-02 GO:0030193 regulation of blood coagulation
19.26 4.93e-02 GO:0030194 positive regulation of blood coagulation

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
2.75 2.38e-05 GO:0005615 extracellular space
2.38 1.43e-04 GO:0044421 extracellular region part
8.43 3.08e-03 GO:0031983 vesicle lumen
7.56 6.39e-03 GO:0031091 platelet alpha granule
7.99 1.70e-02 GO:0031093 platelet alpha granule lumen
7.83 1.91e-02 GO:0034774 secretory granule lumen
26.83 2.37e-02 GO:0005577 fibrinogen complex
7.51 2.41e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
3.56 2.63e-02 GO:0045177 apical part of cell
1.66 3.23e-02 GO:0005576 extracellular region
1.93 4.72e-02 GO:0000267 cell fraction

Gene overrepresentation in function category:

enrichment   p-value GO term description
20.87 7.04e-04 GO:0008514 organic anion transmembrane transporter activity
8.54 1.77e-02 GO:0043498 cell surface binding
3.20 3.58e-02 GO:0004857 enzyme inhibitor activity