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Motif ID: HIF1A.p2

Z-value: 1.720

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_97016027	3.713	NM_001122646	FAM178B	family with sequence similarity 178, member B
chr1_-_26105954	1.508	NM_203399	STMN1	stathmin 1
chr1_-_26105477	1.412	NM_001145454 NM_005563	STMN1	stathmin 1
chr21_+_25856311	1.357		MIR155HG	MIR155 host gene (non-protein coding)
chr10_-_88720908	1.307		LOC100133190	hypothetical LOC100133190
chr10_+_112247614	1.303	NM_004419	DUSP5	dual specificity phosphatase 5
chr8_-_101804114	1.300		PABPC1	poly(A) binding protein, cytoplasmic 1
chr15_-_90999606	1.288	NM_207446	FAM174B	family with sequence similarity 174, member B
chr19_-_53516962	1.286		CCDC114	coiled-coil domain containing 114
chr3_-_180652024	1.242	NM_021629	GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4
chr7_-_72609957	1.221	NM_001197244 NM_001707	BCL7B	B-cell CLL/lymphoma 7B
chr19_+_1358664	1.212		DAZAP1	DAZ associated protein 1
chr3_-_16530132	1.175	NM_015150	RFTN1	raftlin, lipid raft linker 1
chr20_+_18516541	1.164	NM_080820	DTD1	D-tyrosyl-tRNA deacylase 1 homolog (S. cerevisiae)
chr4_-_10068055	1.154	NM_053042	ZNF518B	zinc finger protein 518B
chr3_-_180651874	1.127		GNB4	guanine nucleotide binding protein (G protein), beta polypeptide 4
chr7_+_148590152	1.107	NM_001195220	ZNF783	zinc finger family member 783
chr6_+_33697023	1.092	NM_002224	ITPR3	inositol 1,4,5-triphosphate receptor, type 3
chr3_-_16529996	1.052		RFTN1	raftlin, lipid raft linker 1
chr1_+_13899272	1.051	NM_001135610	PRDM2	PR domain containing 2, with ZNF domain
chr3_-_185025989	1.045	NM_024871	MAP6D1	MAP6 domain containing 1
chr10_+_3099708	1.002	NM_002627	PFKP	phosphofructokinase, platelet
chr17_-_58877276	0.994	NM_001017916 NM_001915	CYB561	cytochrome b-561
chr1_+_12046020	0.993	NM_001243	TNFRSF8	tumor necrosis factor receptor superfamily, member 8
chr13_-_110365282	0.979
chr13_-_43259032	0.978	NM_017993	ENOX1	ecto-NOX disulfide-thiol exchanger 1
chr1_-_158161877	0.963		TAGLN2	transgelin 2
chr18_+_9903954	0.959	NM_003574 NM_194434	VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr8_+_26296439	0.954	NM_004331	BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr1_-_158161902	0.936	NM_003564	TAGLN2	transgelin 2
chr11_+_20341835	0.933	NM_001098520	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr8_+_98725505	0.927	NM_178812	MTDH	metadherin
chr7_-_72609804	0.922		BCL7B	B-cell CLL/lymphoma 7B
chr11_+_20341806	0.911	NM_006410 NM_001098521	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr19_+_1358531	0.901	NM_018959 NM_170711	DAZAP1	DAZ associated protein 1
chr12_-_75983329	0.863	NM_203394	E2F7	E2F transcription factor 7
chr3_-_49030920	0.861	NM_001009996	DALRD3	DALR anticodon binding domain containing 3
chr12_+_129922589	0.860		RAN	RAN, member RAS oncogene family
chr22_-_30016707	0.859		PIK3IP1	phosphoinositide-3-kinase interacting protein 1
chr18_+_9904000	0.850		VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr18_+_9903992	0.847		VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr17_-_7996409	0.845	NM_002616	PER1	period homolog 1 (Drosophila)
chr11_+_20341900	0.833	NM_001098522	HTATIP2	HIV-1 Tat interactive protein 2, 30kDa
chr7_+_2685681	0.833	NM_133463	AMZ1	archaelysin family metallopeptidase 1
chr11_+_94141151	0.829	NM_130847	AMOTL1	angiomotin like 1
chr1_-_84237316	0.822	NM_024686	TTLL7	tubulin tyrosine ligase-like family, member 7
chr18_+_9904060	0.818		VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr10_+_35456393	0.811	NM_181571 NM_183060	CREM	cAMP responsive element modulator
chr18_+_9904032	0.808		VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr12_+_129922570	0.807		RAN	RAN, member RAS oncogene family
chr7_+_44802691	0.799	NM_021130	PPIA	peptidylprolyl isomerase A (cyclophilin A)
chr5_-_88215034	0.794	NM_001193350 NM_002397	MEF2C	myocyte enhancer factor 2C
chr10_-_49534304	0.789		ARHGAP22	Rho GTPase activating protein 22
chr18_+_9904017	0.788		VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr1_+_1540657	0.784	NM_001170686 NM_001170687 NM_001170688 NM_080875	MIB2	mindbomb homolog 2 (Drosophila)
chr18_+_75540831	0.783		CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr5_-_127447197	0.779		FLJ33630	hypothetical LOC644873
chr22_-_22511173	0.779	NM_001002862 NM_001135751 NM_198440	DERL3	Der1-like domain family, member 3
chr11_+_12088639	0.776	NM_014632	MICAL2	microtubule associated monoxygenase, calponin and LIM domain containing 2
chr11_+_32069183	0.769		RCN1	reticulocalbin 1, EF-hand calcium binding domain
chr1_-_8861278	0.769		ENO1	enolase 1, (alpha)
chr3_+_23219707	0.767	NM_152653	UBE2E2	ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
chr2_-_213724577	0.754	NM_001079526	IKZF2	IKAROS family zinc finger 2 (Helios)
chr19_+_1358750	0.751		DAZAP1	DAZ associated protein 1
chr13_-_35818777	0.747	NM_001142295	SPG20	spastic paraplegia 20 (Troyer syndrome)
chr3_+_185514937	0.738	NM_001194946 NM_001194947 NM_198241 NM_198242 NM_198244	EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr3_+_184898234	0.734	NM_018023	YEATS2	YEATS domain containing 2
chr10_-_43390014	0.733	NM_001099282 NM_001099283 NM_001099284	ZNF239	zinc finger protein 239
chr18_+_75540786	0.733	NM_004715 NM_048368	CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr9_-_122516399	0.731	NM_001080497	MEGF9	multiple EGF-like-domains 9
chr4_+_321587	0.731	NM_003441	ZNF141	zinc finger protein 141
chr10_+_90629880	0.731	NM_020799	STAMBPL1	STAM binding protein-like 1
chr13_-_29067795	0.714	NM_003045	SLC7A1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr4_+_321607	0.711		ZNF141	zinc finger protein 141
chr6_+_44295219	0.704	NM_001078174 NM_004955	SLC29A1	solute carrier family 29 (nucleoside transporters), member 1
chrX_-_135161185	0.701	NM_001173517 NM_024597	MAP7D3	MAP7 domain containing 3
chr1_-_1700088	0.700	NM_001198993	NADK	NAD kinase
chr9_+_137532294	0.696	NM_016034	MRPS2	mitochondrial ribosomal protein S2
chrX_+_16714452	0.692	NM_001168683 NM_018360	TXLNG	taxilin gamma
chr3_+_23219490	0.689		UBE2E2	ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
chr3_-_81893604	0.684	NM_000158	GBE1	glucan (1,4-alpha-), branching enzyme 1
chr7_+_44802798	0.680		PPIA	peptidylprolyl isomerase A (cyclophilin A)
chr2_-_144991386	0.672		ZEB2	zinc finger E-box binding homeobox 2
chr2_-_96174502	0.672		DUSP2	dual specificity phosphatase 2
chr18_+_9904202	0.671		VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr20_-_57015698	0.656	NM_001336	CTSZ	cathepsin Z
chr7_+_44802834	0.654		PPIA	peptidylprolyl isomerase A (cyclophilin A)
chrX_+_152252738	0.653	NM_001080485	ZNF275	zinc finger protein 275
chr9_-_139316523	0.652	NM_001004354	NRARP	NOTCH-regulated ankyrin repeat protein
chr2_-_96174865	0.650	NM_004418	DUSP2	dual specificity phosphatase 2
chr3_+_185515013	0.647		EIF4G1	eukaryotic translation initiation factor 4 gamma, 1
chr9_-_109291575	0.644		KLF4	Kruppel-like factor 4 (gut)
chr17_-_3546047	0.640		P2RX5	purinergic receptor P2X, ligand-gated ion channel, 5
chrX_-_47394808	0.626		ELK1	ELK1, member of ETS oncogene family
chr13_-_35818491	0.624		SPG20	spastic paraplegia 20 (Troyer syndrome)
chr8_+_94998258	0.623	NM_018444 NM_001161780 NM_001161779 NM_001161781	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr11_+_13646806	0.622		FAR1	fatty acyl CoA reductase 1
chr3_-_81893506	0.622		GBE1	glucan (1,4-alpha-), branching enzyme 1
chr16_+_711139	0.616	NM_023933	FAM173A	family with sequence similarity 173, member A
chr7_+_27102197	0.615
chr19_-_51608665	0.615	NM_032040	CCDC8	coiled-coil domain containing 8
chr17_-_40263124	0.615	NM_005497	GJC1	gap junction protein, gamma 1, 45kDa
chr8_+_49083522	0.614	NM_003350	UBE2V2	ubiquitin-conjugating enzyme E2 variant 2
chr17_+_1905104	0.614	NM_006497	HIC1	hypermethylated in cancer 1
chr4_+_186554831	0.612	NM_181726	ANKRD37	ankyrin repeat domain 37
chr16_-_87378872	0.610	NM_001142864	FAM38A	family with sequence similarity 38, member A
chr22_+_16020241	0.609		CECR4	cat eye syndrome chromosome region, candidate 4 (non-protein coding)
chr13_-_35818396	0.609		SPG20	spastic paraplegia 20 (Troyer syndrome)
chr1_-_8861332	0.606	NM_001428	ENO1	enolase 1, (alpha)
chr5_+_49998677	0.604		PARP8	poly (ADP-ribose) polymerase family, member 8
chr8_+_22479115	0.599	NM_001018003	SORBS3	sorbin and SH3 domain containing 3
chr15_-_40051979	0.599		EHD4	EH-domain containing 4
chr5_-_1397941	0.597	NM_030782	CLPTM1L	CLPTM1-like
chr14_+_104523660	0.597	NM_174891	C14orf79	chromosome 14 open reading frame 79
chr19_+_1358604	0.596		DAZAP1	DAZ associated protein 1
chr11_+_66381077	0.593		LRFN4	leucine rich repeat and fibronectin type III domain containing 4
chr11_+_13646727	0.592	NM_032228	FAR1	fatty acyl CoA reductase 1
chr10_+_35455806	0.591	NM_001881 NM_182850 NM_182853 NM_183013	CREM	cAMP responsive element modulator
chr7_+_48041632	0.591	NM_001100159	C7orf57	chromosome 7 open reading frame 57
chr2_-_225615556	0.590	NM_014689	DOCK10	dedicator of cytokinesis 10
chr4_-_54625522	0.590		CHIC2	cysteine-rich hydrophobic domain 2
chrX_-_47394937	0.589	NM_001114123 NM_005229	ELK1	ELK1, member of ETS oncogene family
chr5_-_142763418	0.589	NM_000176 NM_001020825 NM_001024094	NR3C1	nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr3_+_157874898	0.588	NM_015508	TIPARP	TCDD-inducible poly(ADP-ribose) polymerase
chr9_+_99785405	0.588		ANP32B	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr19_-_1518875	0.585	NM_001174118 NM_203304	MEX3D	mex-3 homolog D (C. elegans)
chr1_-_8861374	0.584		ENO1	enolase 1, (alpha)
chr1_-_1540904	0.584		MIB2	mindbomb homolog 2 (Drosophila)
chr4_-_54625528	0.583	NM_012110	CHIC2	cysteine-rich hydrophobic domain 2
chrX_+_64804235	0.582	NM_002444	MSN	moesin
chr1_-_1699723	0.581	NM_023018	NADK	NAD kinase
chr1_-_8861314	0.579		ENO1	enolase 1, (alpha)
chr19_-_11352850	0.578		EPOR	erythropoietin receptor
chr8_+_142207866	0.576	NM_014957	DENND3	DENN/MADD domain containing 3
chr6_+_151228757	0.576		MTHFD1L	methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr17_-_44010543	0.574	NM_024015	HOXB4	homeobox B4
chr19_+_37874529	0.570	NM_001105570	NUDT19	nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr4_+_186554886	0.568		ANKRD37	ankyrin repeat domain 37
chr16_-_30504309	0.566	NM_152458	ZNF785	zinc finger protein 785
chr7_+_39739690	0.557		NCRNA00265	non-protein coding RNA 265
chr1_+_148388870	0.556		PLEKHO1	pleckstrin homology domain containing, family O member 1
chr9_-_21984414	0.554	NM_058195	CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr13_-_95503566	0.554	NM_020121	UGGT2	UDP-glucose glycoprotein glucosyltransferase 2
chr1_+_22251706	0.553	NM_001039802 NM_001791 NM_044472	CDC42	cell division cycle 42 (GTP binding protein, 25kDa)
chr12_-_40918417	0.550	NM_001190979 NM_001190980 NM_005748	YAF2	YY1 associated factor 2
chr21_+_44544381	0.549		PFKL	phosphofructokinase, liver
chr4_-_157094443	0.547	NM_001334	CTSO	cathepsin O
chr10_+_35455986	0.546		CREM	cAMP responsive element modulator
chr3_-_81893492	0.546		GBE1	glucan (1,4-alpha-), branching enzyme 1
chrX_+_148430424	0.544	NM_001171907 NM_001171908 NM_178124	CXorf40A	chromosome X open reading frame 40A
chr6_+_73388713	0.543		KCNQ5	potassium voltage-gated channel, KQT-like subfamily, member 5
chr12_+_68923043	0.542	NM_014515	CNOT2	CCR4-NOT transcription complex, subunit 2
chr17_-_28228300	0.542		MYO1D	myosin ID
chr10_+_104394185	0.542	NM_030912	TRIM8	tripartite motif containing 8
chr18_+_54682261	0.541		ZNF532	zinc finger protein 532
chr12_-_105165805	0.537	NM_006825	CKAP4	cytoskeleton-associated protein 4
chr18_+_9904249	0.533		VAPA	VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
chr16_-_674357	0.531	NM_001005920	JMJD8	jumonji domain containing 8
chr1_-_180840016	0.529	NM_002928	RGS16	regulator of G-protein signaling 16
chr4_+_186554958	0.528		ANKRD37	ankyrin repeat domain 37
chr4_-_54625463	0.525		CHIC2	cysteine-rich hydrophobic domain 2
chr19_+_14405100	0.525	NM_002741	PKN1	protein kinase N1
chr14_-_64040072	0.524	NM_006977	ZBTB25	zinc finger and BTB domain containing 25
chr20_-_26137755	0.524		LOC284801	hypothetical protein LOC284801
chr15_+_61356801	0.524	NM_001145646 NM_031301	APH1B	anterior pharynx defective 1 homolog B (C. elegans)
chr13_-_35818603	0.524	NM_001142296 NM_015087	SPG20	spastic paraplegia 20 (Troyer syndrome)
chr6_-_144427340	0.520	NM_001080951 NM_001080955	PLAGL1	pleiomorphic adenoma gene-like 1
chr7_-_98579617	0.520	NM_020429 NM_181349	SMURF1	SMAD specific E3 ubiquitin protein ligase 1
chr13_-_47775797	0.519
chr9_+_81376666	0.518	NM_007005	TLE4	transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr11_+_65357972	0.518	NM_152760	SNX32	sorting nexin 32
chr9_-_109291866	0.517	NM_004235	KLF4	Kruppel-like factor 4 (gut)
chr1_-_35957030	0.508		C1orf216	chromosome 1 open reading frame 216
chr21_-_29179482	0.505	NM_013240 NM_182749	N6AMT1	N-6 adenine-specific DNA methyltransferase 1 (putative)
chr3_-_50349865	0.503		RASSF1	Ras association (RalGDS/AF-6) domain family member 1
chr5_+_98132898	0.502	NM_001012761	RGMB	RGM domain family, member B
chr15_+_46957556	0.501	NM_014335	EID1	EP300 interacting inhibitor of differentiation 1
chr8_+_145718702	0.501
chr6_-_159160386	0.500		EZR	ezrin
chr17_-_63798851	0.499	NM_001174166 NM_004694	SLC16A6	solute carrier family 16, member 6 (monocarboxylic acid transporter 7)
chr5_-_131854325	0.499	NM_002198	IRF1	interferon regulatory factor 1
chr1_-_158161898	0.497		TAGLN2	transgelin 2
chr8_+_75050930	0.496	NM_001040613 NM_017866	TMEM70	transmembrane protein 70
chr13_+_47775887	0.494		RB1	retinoblastoma 1
chr7_+_154720547	0.494		INSIG1	insulin induced gene 1
chr16_+_65840275	0.493	NM_004594	SLC9A5	solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr3_-_81893486	0.493		GBE1	glucan (1,4-alpha-), branching enzyme 1
chr3_+_143078202	0.492		ATP1B3	ATPase, Na+/K+ transporting, beta 3 polypeptide
chr12_-_95317928	0.492		CDK17	cyclin-dependent kinase 17
chr14_-_87529222	0.492		GALC	galactosylceramidase
chr7_-_127012889	0.489	NM_024523	GCC1	GRIP and coiled-coil domain containing 1
chr19_+_1226510	0.489	NM_017914	C19orf24	chromosome 19 open reading frame 24
chr12_+_130979729	0.487	NM_001002019 NM_025215	PUS1	pseudouridylate synthase 1
chr15_-_72922577	0.486	NM_001099436	ULK3	unc-51-like kinase 3 (C. elegans)
chr14_-_87529212	0.486		GALC	galactosylceramidase
chr21_+_46568460	0.486	NM_006031	PCNT	pericentrin
chr11_+_33018136	0.485	NM_001145541	TCP11L1	t-complex 11 (mouse)-like 1
chr16_-_674318	0.485		JMJD8	jumonji domain containing 8
chrX_+_64804259	0.485		MSN	moesin
chr6_-_159160421	0.484	NM_001111077	EZR	ezrin

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.24	2.66e-05	GO:0044260	cellular macromolecule metabolic process
1.19	5.27e-05	GO:0044237	cellular metabolic process
1.35	1.35e-03	GO:0043412	macromolecule modification
1.35	4.11e-03	GO:0006464	protein modification process
1.19	4.67e-03	GO:0043170	macromolecule metabolic process
1.14	4.86e-03	GO:0008152	metabolic process
1.49	5.11e-03	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.23	5.68e-03	GO:0031323	regulation of cellular metabolic process
1.15	6.59e-03	GO:0044238	primary metabolic process
1.23	1.11e-02	GO:0080090	regulation of primary metabolic process
1.30	1.52e-02	GO:0065008	regulation of biological quality
1.20	2.03e-02	GO:0019222	regulation of metabolic process
1.13	2.85e-02	GO:0050794	regulation of cellular process
1.22	3.09e-02	GO:0060255	regulation of macromolecule metabolic process
1.56	3.98e-02	GO:0007167	enzyme linked receptor protein signaling pathway
1.12	4.38e-02	GO:0065007	biological regulation
1.08	4.98e-02	GO:0009987	cellular process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.15	1.08e-17	GO:0005622	intracellular
1.16	1.28e-17	GO:0044424	intracellular part
1.17	4.71e-10	GO:0043231	intracellular membrane-bounded organelle
1.17	6.55e-10	GO:0043227	membrane-bounded organelle
1.15	2.15e-09	GO:0043226	organelle
1.14	3.62e-09	GO:0043229	intracellular organelle
1.24	4.23e-09	GO:0005634	nucleus
1.16	4.08e-08	GO:0005737	cytoplasm
1.05	2.22e-04	GO:0044464	cell part
1.05	2.30e-04	GO:0005623	cell
1.16	2.90e-04	GO:0044444	cytoplasmic part
1.96	2.41e-03	GO:0005635	nuclear envelope
1.29	5.61e-03	GO:0005829	cytosol

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.15	7.42e-05	GO:0005515	protein binding
1.08	2.00e-04	GO:0005488	binding
1.48	1.09e-03	GO:0030528	transcription regulator activity
1.24	1.15e-03	GO:0003676	nucleic acid binding
1.28	2.85e-03	GO:0003677	DNA binding
4.15	7.05e-03	GO:0034061	DNA polymerase activity
1.27	8.57e-03	GO:0000166	nucleotide binding
4.25	1.29e-02	GO:0003887	DNA-directed DNA polymerase activity
1.74	4.00e-02	GO:0016564	transcription repressor activity
1.29	4.20e-02	GO:0016740	transferase activity
6.69	4.59e-02	GO:0070742	C2H2 zinc finger domain binding