Motif ID: NFIL3.p2

Z-value: 0.563


Transcription factors associated with NFIL3.p2:

Gene SymbolEntrez IDGene Name
NFIL3 4783 nuclear factor, interleukin 3 regulated



Activity profile for motif NFIL3.p2.

activity profile for motif NFIL3.p2


Sorted Z-values histogram for motif NFIL3.p2

Sorted Z-values for motif NFIL3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIL3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_123568781 1.373


chr11_+_35596310 0.907 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr4_+_3341521 0.706 NM_198227
RGS12
regulator of G-protein signaling 12
chr8_+_94999167 0.636 NM_001161778
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr20_-_55718982 0.606 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr14_+_95792299 0.600 NM_000710
BDKRB1
bradykinin receptor B1
chr5_-_14924555 0.564 NM_054027
ANKH
ankylosis, progressive homolog (mouse)
chr13_-_32678142 0.508 NM_052851
STARD13
StAR-related lipid transfer (START) domain containing 13
chr17_-_38978772 0.468 NM_001986
ETV4
ets variant 4
chr2_-_192420168 0.461 NM_004657
SDPR
serum deprivation response
chr3_+_152970904 0.440 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr17_-_38979178 0.423 NM_001079675
ETV4
ets variant 4
chr16_-_52094613 0.407 NM_001012398
NM_022476
AKTIP

AKT interacting protein

chr10_-_82039158 0.401 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr15_-_53996597 0.390 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr13_-_43908937 0.385 TSC22D1
TSC22 domain family, member 1
chr13_+_96726415 0.365 MBNL2
muscleblind-like 2 (Drosophila)
chr2_-_238861830 0.350 NM_022817
PER2
period homolog 2 (Drosophila)
chr8_-_72436832 0.338 EYA1
eyes absent homolog 1 (Drosophila)
chr7_+_134114701 0.334 NM_004342
NM_033138
NM_033157
CALD1


caldesmon 1


chr2_+_148319033 0.330 NM_001616
ACVR2A
activin A receptor, type IIA
chr9_-_72218098 0.328 KLF9
Kruppel-like factor 9
chr4_+_74488947 0.326 ALB
albumin
chr5_+_36642424 0.325 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr8_+_69026895 0.319 PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr4_+_74488910 0.319 ALB
albumin
chr5_+_36642213 0.307 NM_001166696
NM_004172
SLC1A3

solute carrier family 1 (glial high affinity glutamate transporter), member 3

chr4_+_146820805 0.306 NM_001080531
C4orf51
chromosome 4 open reading frame 51
chr4_-_153820535 0.302 NM_152680
TMEM154
transmembrane protein 154
chr8_-_72437020 0.299 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chr1_-_177378801 0.299 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr20_+_2030527 0.288 NM_080836
STK35
serine/threonine kinase 35
chr18_+_19286784 0.287 NM_003831
RIOK3
RIO kinase 3 (yeast)
chrX_-_33139349 0.283 NM_004006
DMD
dystrophin
chr1_+_194887630 0.279 NM_000186
NM_001014975
CFH

complement factor H

chr7_+_28692122 0.277 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr5_-_38592439 0.277 NM_001127671
LIFR
leukemia inhibitory factor receptor alpha
chr5_-_111119846 0.277 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr4_+_74488835 0.276 NM_000477
ALB
albumin
chr18_-_35634247 0.273 LOC647946
hypothetical LOC647946
chr10_-_95350949 0.271 NM_006744
RBP4
retinol binding protein 4, plasma
chr13_-_79810972 0.262 SPRY2
sprouty homolog 2 (Drosophila)
chr4_+_144477432 0.258 NM_002039
NM_207123
GAB1

GRB2-associated binding protein 1

chr20_+_4614796 0.253 NM_000311
NM_001080121
NM_001080122
NM_183079
NM_001080123
PRNP




prion protein




chr8_+_70567581 0.238 NM_001128205
NM_001128206
SULF1

sulfatase 1

chr9_+_27514311 0.230 NM_020124
IFNK
interferon, kappa
chr4_-_159311959 0.226 FAM198B
family with sequence similarity 198, member B
chr9_-_72219359 0.224 NM_001206
KLF9
Kruppel-like factor 9
chr9_+_674193 0.217


chr8_+_70567634 0.209 SULF1
sulfatase 1
chr10_-_52315436 0.206 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr16_+_7322751 0.206 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr4_+_187424336 0.205 F11
coagulation factor XI
chr22_+_39817733 0.201 EP300
E1A binding protein p300
chr1_-_109957195 0.200 NM_005272
GNAT2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr6_-_133076873 0.198 NM_004666
VNN1
vanin 1
chr2_+_178893216 0.198 NM_145739
OSBPL6
oxysterol binding protein-like 6
chr17_+_36493927 0.193 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr22_-_48607199 0.189 BRD1
bromodomain containing 1
chr1_+_57093030 0.189 NM_000562
C8A
complement component 8, alpha polypeptide
chr19_-_53305825 0.179 NM_001159322
NM_001159323
NM_003706
PLA2G4C


phospholipase A2, group IVC (cytosolic, calcium-independent)


chr3_-_101077605 0.179 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr1_+_205328834 0.173 NM_001017365
NM_001017366
C4BPB

complement component 4 binding protein, beta

chr3_-_113842652 0.172 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr8_-_17599438 0.172 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr12_+_15955499 0.172 DERA
deoxyribose-phosphate aldolase (putative)
chr4_+_120167264 0.171 SYNPO2
synaptopodin 2
chr3_+_23962518 0.170 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr14_+_93646831 0.164 NM_001130080
NM_005532
IFI27

interferon, alpha-inducible protein 27

chr17_-_34209671 0.164 NM_003559
PIP4K2B
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr10_-_119795663 0.160 NM_014904
RAB11FIP2
RAB11 family interacting protein 2 (class I)
chrX_-_131375217 0.157 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr1_-_148818701 0.152 MCL1
myeloid cell leukemia sequence 1 (BCL2-related)
chr16_+_68890559 0.151 NM_001014449
NM_001014451
NM_007242
DDX19B


DEAD (Asp-Glu-Ala-As) box polypeptide 19B


chr14_+_61532293 0.149 NM_031914
SYT16
synaptotagmin XVI
chr13_-_24644304 0.149 FAM123A
family with sequence similarity 123A
chr5_-_94442941 0.149 MCTP1
multiple C2 domains, transmembrane 1
chr8_-_17797127 0.146 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr2_-_228290942 0.145 NM_025243
SLC19A3
solute carrier family 19, member 3
chr11_-_116168316 0.145 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr3_+_156280604 0.145 NM_007288
MME
membrane metallo-endopeptidase
chr5_+_134237325 0.144 NM_024715
TXNDC15
thioredoxin domain containing 15
chr2_-_133895795 0.144 NCKAP5
NCK-associated protein 5
chr8_-_110689396 0.144 SYBU
syntabulin (syntaxin-interacting)
chr7_-_37923040 0.141 NM_003014
SFRP4
secreted frizzled-related protein 4
chr8_-_130868315 0.140 NM_031415
GSDMC
gasdermin C
chr8_+_17440664 0.139 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr12_-_41164052 0.138 NM_001144882
NM_001144883
PRICKLE1

prickle homolog 1 (Drosophila)

chr12_-_121753795 0.137 NM_177551
GPR109A
G protein-coupled receptor 109A
chr10_-_69095362 0.137 NM_001127384
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr5_-_139993469 0.136 NM_001040021
NM_001174104
NM_001174105
CD14


CD14 molecule


chr2_+_87536106 0.135 NCRNA00152
non-protein coding RNA 152
chr3_-_187309442 0.135 NM_004454
ETV5
ets variant 5
chr5_-_139992621 0.133 NM_000591
CD14
CD14 molecule
chr9_-_78198867 0.132 NM_018339
RFK
riboflavin kinase
chr6_-_28429950 0.132 NM_145909
ZNF323
zinc finger protein 323
chr17_+_38250122 0.132 NM_001158
NM_009590
AOC2

amine oxidase, copper containing 2 (retina-specific)

chr1_-_150862202 0.132 NM_178431
LCE3A
late cornified envelope 3A
chr20_+_57729659 0.131 NM_183244
NM_183246
PHACTR3

phosphatase and actin regulator 3

chr7_-_31347032 0.130 NM_022728
NEUROD6
neurogenic differentiation 6
chr17_+_36515166 0.130 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr19_-_20011013 0.130 NM_001077349
ZNF682
zinc finger protein 682
chr14_-_69333624 0.129 NM_003049
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter family), member 1
chr12_+_54316910 0.128 NM_206899
OR10P1
olfactory receptor, family 10, subfamily P, member 1
chr16_+_24648446 0.127 NM_014494
TNRC6A
trinucleotide repeat containing 6A
chr4_+_1864306 0.125 NM_007331
NM_133330
NM_133331
NM_133335
WHSC1



Wolf-Hirschhorn syndrome candidate 1



chr1_-_159474503 0.124 NM_001077469
NM_001077470
NM_001077471
NM_001077472
NM_001077473
NM_001077474
NM_001077475
NM_001077476
NM_001077477
NM_001077478
NM_001077479
NM_001077480
NM_001077481
NM_001077482
NM_005122
NR1I3














nuclear receptor subfamily 1, group I, member 3














chr3_-_195670256 0.123 NM_024524
ATP13A3
ATPase type 13A3
chr2_-_40510923 0.122 NM_001112800
NM_001112801
NM_021097
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr20_-_43889339 0.121 NM_003279
TNNC2
troponin C type 2 (fast)
chr6_-_2785682 0.121 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr1_-_148818751 0.120 NM_001197320
NM_021960
NM_182763
MCL1


myeloid cell leukemia sequence 1 (BCL2-related)


chr6_+_153060722 0.119 NM_025107
MYCT1
myc target 1
chr3_+_187813538 0.119 NM_001622
AHSG
alpha-2-HS-glycoprotein
chr10_-_14412813 0.118 NM_018027
FRMD4A
FERM domain containing 4A
chr11_-_83661878 0.118 NM_001142700
DLG2
discs, large homolog 2 (Drosophila)
chr6_-_152664906 0.118 SYNE1
spectrin repeat containing, nuclear envelope 1
chr18_+_20294590 0.118 NM_001143828
NM_001160166
NM_021624
HRH4


histamine receptor H4


chr2_+_87536174 0.118 NCRNA00152
non-protein coding RNA 152
chr2_-_188127294 0.117 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr4_-_87989291 0.116 NM_197965
SLC10A6
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr1_-_220788048 0.114 NM_024746
HHIPL2
HHIP-like 2
chr8_-_86441115 0.114 NM_001164830
CA1
carbonic anhydrase I
chr6_-_136888771 0.114 NM_001198608
NM_001198609
NM_001198611
MAP7


microtubule-associated protein 7


chr1_+_195213289 0.114 NM_030787
CFHR5
complement factor H-related 5
chr4_+_81325447 0.112 NM_020226
PRDM8
PR domain containing 8
chr3_+_134976965 0.111 TF
transferrin
chr2_-_104834344 0.111 LOC100506421
hypothetical LOC100506421
chr14_-_66896167 0.110 NM_015994
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr7_-_112513379 0.109 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr4_+_111616630 0.108 NM_001977
ENPEP
glutamyl aminopeptidase (aminopeptidase A)
chr10_-_102663070 0.106


chr13_+_96797290 0.104


chr2_-_188021117 0.103 NM_005795
CALCRL
calcitonin receptor-like
chr6_+_64289585 0.103 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr1_+_11171967 0.102 NM_021146
ANGPTL7
angiopoietin-like 7
chr2_-_74606819 0.101 NM_133637
DQX1
DEAQ box RNA-dependent ATPase 1
chr13_+_113546943 0.101 GAS6
growth arrest-specific 6
chr3_-_150858274 0.100 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr1_-_148818629 0.100 MCL1
myeloid cell leukemia sequence 1 (BCL2-related)
chr16_+_70654625 0.098 NM_020995
HPR
haptoglobin-related protein
chr2_-_88208650 0.097 NM_001443
FABP1
fatty acid binding protein 1, liver
chr4_+_141397889 0.096 NM_032547
SCOC
short coiled-coil protein
chr5_-_43593277 0.094 NM_183323
PAIP1
poly(A) binding protein interacting protein 1
chr1_+_7767300 0.094 NM_016831
PER3
period homolog 3 (Drosophila)
chr8_-_102287044 0.092 NM_001042511
ZNF706
zinc finger protein 706
chrX_+_1670485 0.091 NM_005088
AKAP17A
A kinase (PRKA) anchor protein 17A
chr8_-_27524744 0.091 NM_203339
CLU
clusterin
chr6_+_134800533 0.090 LOC154092
hypothetical LOC154092
chr11_+_57547928 0.089 NM_001005212
OR9Q1
olfactory receptor, family 9, subfamily Q, member 1
chr3_+_156280539 0.089 MME
membrane metallo-endopeptidase
chr2_+_102294393 0.089 NM_016232
IL18R1
IL1RL1
interleukin 18 receptor 1
interleukin 1 receptor-like 1
chr10_-_73953699 0.088 NM_001195519
CBARA1
calcium binding atopy-related autoantigen 1
chr1_-_245763763 0.088 NM_198074
OR2C3
olfactory receptor, family 2, subfamily C, member 3
chr3_+_187813553 0.087 AHSG
alpha-2-HS-glycoprotein
chr20_+_23419765 0.086 NM_005492
CST8
cystatin 8 (cystatin-related epididymal specific)
chr6_-_24597717 0.086 NM_177483
NM_001503
GPLD1

glycosylphosphatidylinositol specific phospholipase D1

chr12_-_116283793 0.085 NM_000620
NOS1
nitric oxide synthase 1 (neuronal)
chr20_+_33223434 0.085 NM_006404
PROCR
protein C receptor, endothelial
chr12_+_15955549 0.083 DERA
deoxyribose-phosphate aldolase (putative)
chr1_+_15145001 0.083 NM_001017999
KAZN
kazrin, periplakin interacting protein
chr1_+_47305633 0.083 NM_178134
CYP4Z1
cytochrome P450, family 4, subfamily Z, polypeptide 1
chr4_+_155703581 0.083 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr12_+_15955372 0.082 NM_015954
DERA
deoxyribose-phosphate aldolase (putative)
chr2_+_190916440 0.082 NM_001128928
NM_002194
INPP1

inositol polyphosphate-1-phosphatase

chr12_-_69317441 0.082 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr7_+_45899621 0.081


chr13_+_113546912 0.081 GAS6
growth arrest-specific 6
chr4_-_24590867 0.080 NM_173463
CCDC149
coiled-coil domain containing 149
chr19_+_56671649 0.079 NM_001080405
CEACAM18
carcinoembryonic antigen-related cell adhesion molecule 18
chr2_-_224611568 0.078 NM_001136530
SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr17_-_36528113 0.078 NM_033059
KRTAP4-11
keratin associated protein 4-11
chr12_+_27740694 0.078 NM_001029874
REP15
RAB15 effector protein
chr18_+_75261231 0.077 NM_172387
NM_172389
NFATC1

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1

chr4_+_110574376 0.077 NM_001042734
NM_006323
SEC24B

SEC24 family, member B (S. cerevisiae)

chr2_+_190916571 0.075 INPP1
inositol polyphosphate-1-phosphatase
chr7_+_80145461 0.075 CD36
CD36 molecule (thrombospondin receptor)
chr3_-_11598829 0.074 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr21_+_17841297 0.073 CXADR
coxsackie virus and adenovirus receptor
chr3_+_120984246 0.072 NM_022002
NR1I2
nuclear receptor subfamily 1, group I, member 2
chrX_-_77801480 0.072 NM_152694
ZCCHC5
zinc finger, CCHC domain containing 5
chr3_+_42107711 0.071 NM_001042646
TRAK1
trafficking protein, kinesin binding 1
chr1_+_226352179 0.071 ARF1
ADP-ribosylation factor 1
chr17_-_39340414 0.070 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr2_+_233961538 0.070 NM_003648
DGKD
diacylglycerol kinase, delta 130kDa
chr3_+_62280435 0.070 NM_020685
C3orf14
chromosome 3 open reading frame 14
chr4_-_110574363 0.069 1/2-SBSRNA4
lncRNA_BC009800
chr2_+_160180049 0.068 LOC643072
hypothetical LOC643072
chr12_-_121767272 0.067 NM_006018
GPR109B
G protein-coupled receptor 109B
chr22_+_49272078 0.066 NM_017584
MIOX
myo-inositol oxygenase
chr7_-_122627235 0.066 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr2_-_31491057 0.066 XDH
xanthine dehydrogenase
chr5_+_140235114 0.066 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr10_-_64698831 0.066 NM_004241
JMJD1C
jumonji domain containing 1C
chr4_-_70396167 0.066 NM_021139
UGT2B4
UDP glucuronosyltransferase 2 family, polypeptide B4
chr1_+_243199690 0.065 NM_032328
EFCAB2
EF-hand calcium binding domain 2
chr5_-_94443300 0.065 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr2_-_31491102 0.064 NM_000379
XDH
xanthine dehydrogenase
chrX_+_102078855 0.064 NM_001031834
RAB40AL
RAB40A, member RAS oncogene family-like
chr4_-_69218909 0.063 NM_001076
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.59 1.17e-02 GO:0042221 response to chemical stimulus

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.74 2.89e-05 GO:0005576 extracellular region
2.12 3.28e-05 GO:0044421 extracellular region part
2.28 5.67e-05 GO:0005615 extracellular space
1.34 1.98e-02 GO:0005886 plasma membrane
1.33 2.54e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

enrichment   p-value GO term description
29.29 2.31e-02 GO:0047023 androsterone dehydrogenase activity
3.43 3.82e-02 GO:0005539 glycosaminoglycan binding
3.84 4.79e-02 GO:0008201 heparin binding