Motif ID: MYFfamily.p2

Z-value: 2.075


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)



Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_45498354 4.515 RUNX2
runt-related transcription factor 2
chr6_+_45498262 3.396 RUNX2
runt-related transcription factor 2
chr12_-_74710741 2.400 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr6_+_129245978 1.992 NM_000426
NM_001079823
LAMA2

laminin, alpha 2

chr6_+_107917965 1.825 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr4_+_3046034 1.775 NM_002111
HTT
huntingtin
chr18_+_59788242 1.714 NM_001031848
NM_002640
NM_198833
SERPINB8


serpin peptidase inhibitor, clade B (ovalbumin), member 8


chr2_-_227372574 1.707 IRS1
insulin receptor substrate 1
chr9_+_35896188 1.670 NM_001039792
HRCT1
histidine rich carboxyl terminus 1
chr14_+_58174489 1.610 NM_001079520
NM_016651
DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

chr1_-_72521079 1.588


chr5_-_178705036 1.503 NM_014244
NM_021599
ADAMTS2

ADAM metallopeptidase with thrombospondin type 1 motif, 2

chr3_-_126257425 1.430 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr17_+_14145051 1.412 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr1_-_56817802 1.402 PPAP2B
phosphatidic acid phosphatase type 2B
chr12_-_74711474 1.392 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr13_-_34948758 1.378 NM_005584
MAB21L1
mab-21-like 1 (C. elegans)
chr22_+_20068039 1.374 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr10_+_89409332 1.338 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr18_-_21185968 1.329 ZNF521
zinc finger protein 521
chrX_-_92815222 1.313 NM_004538
NAP1L3
nucleosome assembly protein 1-like 3
chr1_+_78126787 1.309 NM_001172309
NM_144573
NEXN

nexilin (F actin binding protein)

chr17_-_15104768 1.300 NM_153322
PMP22
peripheral myelin protein 22
chr9_-_130980302 1.279 IER5L
immediate early response 5-like
chr22_-_20235372 1.265 NM_001128635
RIMBP3B
RIMS binding protein 3B
chr5_-_178704934 1.251 ADAMTS2
ADAM metallopeptidase with thrombospondin type 1 motif, 2
chr12_-_105165805 1.218 NM_006825
CKAP4
cytoskeleton-associated protein 4
chr17_+_1906262 1.206 NM_001098202
HIC1
hypermethylated in cancer 1
chr12_-_74711642 1.175 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr10_+_120957084 1.169 NM_005308
GRK5
G protein-coupled receptor kinase 5
chr14_-_24588916 1.166 NM_014178
STXBP6
syntaxin binding protein 6 (amisyn)
chr17_+_36493927 1.163 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr18_-_24010944 1.138 CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr2_-_227371698 1.132 NM_005544
IRS1
insulin receptor substrate 1
chr16_-_71650034 1.126 NM_001164766
ZFHX3
zinc finger homeobox 3
chr13_+_34948885 1.111 NBEA
neurobeachin
chr22_-_19122047 1.096 SCARF2
scavenger receptor class F, member 2
chr8_-_23768242 1.081 NM_003155
STC1
stanniocalcin 1
chr18_-_21186107 1.079 NM_015461
ZNF521
zinc finger protein 521
chr3_+_160964574 1.058 SCHIP1
schwannomin interacting protein 1
chr12_+_64504835 1.052 HMGA2
high mobility group AT-hook 2
chr1_-_72520735 1.048 NM_173808
NEGR1
neuronal growth regulator 1
chr4_-_140696740 1.046 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chrX_-_135677022 1.045 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr8_+_106400322 1.037 NM_012082
ZFPM2
zinc finger protein, multitype 2
chr2_-_161058120 1.021 RBMS1
RNA binding motif, single stranded interacting protein 1
chr16_+_85101734 1.004 FOXF1
forkhead box F1
chr17_+_36515166 0.983 NM_001146041
KRTAP4-9
keratin associated protein 4-9
chr1_+_219119623 0.973 HLX
H2.0-like homeobox
chr4_-_57671273 0.969 NM_001553
IGFBP7
insulin-like growth factor binding protein 7
chr4_-_57671112 0.967 IGFBP7
insulin-like growth factor binding protein 7
chr3_-_130807865 0.961 NM_015103
PLXND1
plexin D1
chr4_-_57671307 0.953 IGFBP7
insulin-like growth factor binding protein 7
chr1_-_56817568 0.946 PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_56817717 0.944 PPAP2B
phosphatidic acid phosphatase type 2B
chr16_+_29731058 0.942 PRRT2
proline-rich transmembrane protein 2
chr8_+_104452961 0.940 NM_138455
CTHRC1
collagen triple helix repeat containing 1
chr15_-_53822468 0.939 NM_173814
PRTG
protogenin
chr16_+_85101605 0.939 NM_001451
FOXF1
forkhead box F1
chr10_+_111755715 0.938 NM_019903
ADD3
adducin 3 (gamma)
chr20_+_2743613 0.923 NM_080739
C20orf141
chromosome 20 open reading frame 141
chr4_+_159311353 0.918 LOC285505
hypothetical protein LOC285505
chr3_+_112273352 0.917 PVRL3
poliovirus receptor-related 3
chr17_-_36469869 0.910 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr2_+_54536780 0.907 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr6_-_111911029 0.893 REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr3_+_112273464 0.883 NM_015480
PVRL3
poliovirus receptor-related 3
chr12_-_6535481 0.880 NM_001039670
NM_001193457
NM_080730
IFFO1


intermediate filament family orphan 1


chr12_-_110521407 0.870 ATXN2
ataxin 2
chr3_+_45611180 0.860 NM_014240
LIMD1
LIM domains containing 1
chr2_-_216944911 0.851 NM_020814
MARCH4
membrane-associated ring finger (C3HC4) 4
chr13_+_109757593 0.849 NM_001846
COL4A2
collagen, type IV, alpha 2
chr2_+_36436873 0.843 NM_016441
CRIM1
cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr11_+_65594361 0.839 NM_018026
PACS1
phosphofurin acidic cluster sorting protein 1
chr15_-_90999606 0.839 NM_207446
FAM174B
family with sequence similarity 174, member B
chr9_+_101623957 0.833 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr1_-_199704773 0.825 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr10_+_116571485 0.824 NM_001135051
NM_020940
FAM160B1

family with sequence similarity 160, member B1

chr9_-_83494198 0.821 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr17_+_35853177 0.814 NM_001552
IGFBP4
insulin-like growth factor binding protein 4
chr3_-_87122936 0.808 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr2_-_161058550 0.808 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr8_+_37773991 0.804 GPR124
G protein-coupled receptor 124
chr15_+_89229275 0.802 NM_001143783
NM_001143784
FES

feline sarcoma oncogene

chr15_+_90738108 0.800 NM_006011
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr8_+_104452877 0.798 CTHRC1
collagen triple helix repeat containing 1
chr14_+_99220349 0.791 NM_006668
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr17_-_36475652 0.786 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr5_+_92946348 0.785 NR2F1
nuclear receptor subfamily 2, group F, member 1
chr12_+_62523648 0.781


chr4_-_120769275 0.768 NM_001083
PDE5A
phosphodiesterase 5A, cGMP-specific
chr13_+_113546912 0.761 GAS6
growth arrest-specific 6
chr5_-_112852425 0.757 NM_001085377
MCC
mutated in colorectal cancers
chr1_-_59020875 0.754 JUN
jun proto-oncogene
chr21_-_27139143 0.751 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr9_-_130980359 0.748 NM_203434
IER5L
immediate early response 5-like
chr13_-_22905822 0.747 NM_014363
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr16_+_4370879 0.745 VASN
vasorin
chr11_+_32069183 0.744 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr4_+_72271218 0.737 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr4_+_169989680 0.735 NM_001166110
PALLD
palladin, cytoskeletal associated protein
chr5_+_126654354 0.734 NM_032446
MEGF10
multiple EGF-like-domains 10
chr9_+_133154896 0.728 NM_032728
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr18_-_59185330 0.728 NM_002035
KDSR
3-ketodihydrosphingosine reductase
chr9_-_25668230 0.726 TUSC1
tumor suppressor candidate 1
chr3_-_87122958 0.719 VGLL3
vestigial like 3 (Drosophila)
chr10_+_52504239 0.716 NM_006258
PRKG1
protein kinase, cGMP-dependent, type I
chr1_-_143786993 0.716 NM_022359
PDE4DIP
phosphodiesterase 4D interacting protein
chr12_+_26239755 0.710 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr2_+_187266899 0.708 NM_177454
FAM171B
family with sequence similarity 171, member B
chr21_+_46226072 0.708 NM_001848
COL6A1
collagen, type VI, alpha 1
chr2_-_217267742 0.707 IGFBP5
insulin-like growth factor binding protein 5
chr12_+_6807831 0.707 NM_014262
LEPREL2
leprecan-like 2
chr6_-_91063181 0.704 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr2_-_160972606 0.702 RBMS1
RNA binding motif, single stranded interacting protein 1
chr15_+_89228668 0.702 NM_001143785
NM_002005
FES

feline sarcoma oncogene

chr9_-_128924706 0.700 ANGPTL2
angiopoietin-like 2
chr17_-_36456949 0.700 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr10_+_90629880 0.699 NM_020799
STAMBPL1
STAM binding protein-like 1
chr4_-_142273881 0.696 NM_020724
RNF150
ring finger protein 150
chr8_-_72918697 0.695 MSC
musculin
chr9_-_128924782 0.693 ANGPTL2
angiopoietin-like 2
chr9_+_77695334 0.693 NM_001190482
NM_006200
PCSK5

proprotein convertase subtilisin/kexin type 5

chr9_+_132700567 0.688 NM_005157
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr6_-_56816403 0.687 DST
dystonin
chr15_-_46724360 0.687 FBN1
fibrillin 1
chr7_+_93861808 0.685 NM_000089
COL1A2
collagen, type I, alpha 2
chr3_-_73756668 0.685 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr19_-_50977592 0.673 NM_001081560
NM_001081562
NM_004409
DMPK


dystrophia myotonica-protein kinase


chr6_-_31347867 0.672 HLA-C
major histocompatibility complex, class I, C
chrX_+_53095230 0.667 NM_018969
GPR173
G protein-coupled receptor 173
chr6_-_31347805 0.664 NM_002117
HLA-C
major histocompatibility complex, class I, C
chrX_-_19815526 0.664 SH3KBP1
SH3-domain kinase binding protein 1
chr4_-_120769590 0.660


chr2_+_191453791 0.659 NM_014905
GLS
glutaminase
chr13_-_109236897 0.659 NM_003749
IRS2
insulin receptor substrate 2
chr19_-_50977586 0.658 DMPK
dystrophia myotonica-protein kinase
chr9_+_132700462 0.653 ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr14_-_26136799 0.650 NM_002515
NM_006489
NM_006491
NOVA1


neuro-oncological ventral antigen 1


chr17_+_58058774 0.642 MRC2
mannose receptor, C type 2
chr22_+_19699441 0.640 NM_001159554
NM_005446
P2RX6

purinergic receptor P2X, ligand-gated ion channel, 6

chr9_+_136673534 0.639 COL5A1
collagen, type V, alpha 1
chr1_+_216586199 0.635 TGFB2
transforming growth factor, beta 2
chrX_+_46318135 0.634 NM_019886
CHST7
carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
chr8_+_37672427 0.632 NM_025069
ZNF703
zinc finger protein 703
chr2_+_191453813 0.632 GLS
glutaminase
chr19_-_50977485 0.630 DMPK
dystrophia myotonica-protein kinase
chr7_+_90731671 0.628 NM_003505
FZD1
frizzled homolog 1 (Drosophila)
chr9_-_128924819 0.627 NM_012098
ANGPTL2
angiopoietin-like 2
chr16_-_73198416 0.624 GLG1
golgi glycoprotein 1
chr10_+_124210980 0.623 NM_002775
HTRA1
HtrA serine peptidase 1
chr6_-_111911106 0.619 NM_002912
REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chrX_+_109548940 0.619 NM_020769
RGAG1
retrotransposon gag domain containing 1
chr16_-_30983909 0.617 NM_001172669
NM_001172670
ZNF668

zinc finger protein 668

chr14_+_101500650 0.613 DYNC1H1
dynein, cytoplasmic 1, heavy chain 1
chr3_-_49370682 0.613 GPX1
glutathione peroxidase 1
chr12_-_54387934 0.612 NM_001144996
NM_002206
ITGA7

integrin, alpha 7

chr13_+_113546943 0.611 GAS6
growth arrest-specific 6
chr1_+_67163165 0.609 NM_001077700
NM_001077702
NM_001077703
NM_001146110
NM_001146111
NM_001146112
NM_001146113
NM_020948
MIER1







mesoderm induction early response 1 homolog (Xenopus laevis)







chr17_+_72883759 0.603 NM_001113494
SEPT9
septin 9
chr13_+_30378311 0.596 NM_032849
C13orf33
chromosome 13 open reading frame 33
chr1_-_36589744 0.595


chr6_+_114285209 0.595 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr1_-_29321599 0.592 NM_001171868
TMEM200B
transmembrane protein 200B
chr9_+_98252200 0.582 NM_014282
HABP4
hyaluronan binding protein 4
chr22_+_44828338 0.580


chr16_-_73830480 0.577 NM_001170721
BCAR1
breast cancer anti-estrogen resistance 1
chrX_-_19815370 0.576 SH3KBP1
SH3-domain kinase binding protein 1
chr4_+_14614462 0.573 CPEB2
cytoplasmic polyadenylation element binding protein 2
chr4_+_2783764 0.570 SH3BP2
SH3-domain binding protein 2
chr14_-_74148422 0.567 NM_000428
LTBP2
latent transforming growth factor beta binding protein 2
chr11_-_6298284 0.567 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chr12_+_26239535 0.566 NM_001135823
SSPN
sarcospan (Kras oncogene-associated gene)
chr4_+_109072120 0.565 NM_183075
CYP2U1
cytochrome P450, family 2, subfamily U, polypeptide 1
chr7_+_93862137 0.565 COL1A2
PLAG1
collagen, type I, alpha 2
pleiomorphic adenoma gene 1
chr11_-_10272256 0.555 NM_030962
SBF2
SET binding factor 2
chr3_-_147361465 0.553 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr20_-_33489383 0.548 NM_000557
GDF5
growth differentiation factor 5
chr1_-_32479785 0.540 MTMR9LP
myotubularin related protein 9-like, pseudogene
chr1_-_35431318 0.539 SFPQ
splicing factor proline/glutamine-rich
chr18_+_19848749 0.539 TTC39C
tetratricopeptide repeat domain 39C
chr5_-_59225377 0.538 NM_001104631
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_-_54387732 0.538 ITGA7
integrin, alpha 7
chr1_+_167342149 0.537 ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr18_-_53621277 0.537 NM_005603
ATP8B1
ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr6_-_143307976 0.535 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr20_+_43953428 0.533 CTSA
cathepsin A
chr3_-_49424506 0.529 RHOA
ras homolog gene family, member A
chr22_+_19248733 0.528 MED15
mediator complex subunit 15
chr8_-_72918938 0.527 MSC
musculin
chr12_-_88270128 0.523 DUSP6
dual specificity phosphatase 6
chr18_-_24011349 0.522 NM_001792
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr13_+_113546897 0.522 GAS6
growth arrest-specific 6
chr17_-_74433048 0.521 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr11_-_72698050 0.520 LOC100287837
hypothetical protein LOC100287837
chr4_-_17632456 0.520 NM_001166139
NM_153686
LCORL

ligand dependent nuclear receptor corepressor-like

chr10_+_71833866 0.520 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr4_+_81325447 0.519 NM_020226
PRDM8
PR domain containing 8
chr11_+_117982422 0.518 NM_015157
PHLDB1
pleckstrin homology-like domain, family B, member 1
chr10_+_71833905 0.514 EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.25 2.37e-09 GO:0007165 signal transduction
1.23 6.53e-09 GO:0023052 signaling
1.22 1.19e-07 GO:0032502 developmental process
1.23 2.52e-07 GO:0007275 multicellular organismal development
1.33 3.53e-07 GO:0007166 cell surface receptor linked signaling pathway
1.25 3.83e-07 GO:0048731 system development
1.23 8.41e-07 GO:0048856 anatomical structure development
1.36 1.11e-06 GO:0009653 anatomical structure morphogenesis
1.16 6.85e-06 GO:0032501 multicellular organismal process
1.28 7.61e-06 GO:0030154 cell differentiation
1.28 1.45e-05 GO:0048869 cellular developmental process
1.18 2.02e-05 GO:0051716 cellular response to stimulus
1.43 5.36e-05 GO:0048699 generation of neurons
1.32 6.41e-05 GO:0007399 nervous system development
1.30 8.32e-05 GO:0023051 regulation of signaling
1.46 9.60e-05 GO:0007155 cell adhesion
1.46 9.60e-05 GO:0022610 biological adhesion
1.24 1.40e-04 GO:0042221 response to chemical stimulus
1.40 1.68e-04 GO:0048468 cell development
1.40 1.70e-04 GO:0022008 neurogenesis
1.10 1.86e-04 GO:0065007 biological regulation
1.12 1.91e-04 GO:0050794 regulation of cellular process
1.47 4.55e-04 GO:0007167 enzyme linked receptor protein signaling pathway
1.57 6.07e-04 GO:0048812 neuron projection morphogenesis
1.53 9.52e-04 GO:0031175 neuron projection development
1.39 9.85e-04 GO:0040011 locomotion
1.52 1.04e-03 GO:0000904 cell morphogenesis involved in differentiation
1.57 1.19e-03 GO:0007409 axonogenesis
1.12 1.22e-03 GO:0050896 response to stimulus
1.25 1.25e-03 GO:0048583 regulation of response to stimulus
1.10 1.37e-03 GO:0050789 regulation of biological process
1.55 1.40e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.41 1.44e-03 GO:2000026 regulation of multicellular organismal development
1.29 1.67e-03 GO:0009966 regulation of signal transduction
1.37 1.80e-03 GO:0050793 regulation of developmental process
1.47 1.86e-03 GO:0048666 neuron development
1.50 3.07e-03 GO:0048858 cell projection morphogenesis
1.51 3.17e-03 GO:0072358 cardiovascular system development
1.51 3.17e-03 GO:0072359 circulatory system development
1.73 3.64e-03 GO:0030168 platelet activation
1.42 3.67e-03 GO:0030182 neuron differentiation
1.44 3.91e-03 GO:0032989 cellular component morphogenesis
1.66 4.55e-03 GO:0061061 muscle structure development
1.49 4.70e-03 GO:0001775 cell activation
1.48 5.06e-03 GO:0032990 cell part morphogenesis
1.60 6.31e-03 GO:0007411 axon guidance
1.29 6.74e-03 GO:0051239 regulation of multicellular organismal process
1.44 7.53e-03 GO:0000902 cell morphogenesis
1.42 9.32e-03 GO:0030030 cell projection organization
1.46 1.17e-02 GO:0006935 chemotaxis
1.46 1.17e-02 GO:0042330 taxis
1.32 1.56e-02 GO:0009605 response to external stimulus
1.49 1.66e-02 GO:0051094 positive regulation of developmental process
1.41 1.88e-02 GO:0009725 response to hormone stimulus
1.31 1.94e-02 GO:0010646 regulation of cell communication
1.59 3.76e-02 GO:0001944 vasculature development
2.97 4.62e-02 GO:0061035 regulation of cartilage development
2.06 4.64e-02 GO:0030326 embryonic limb morphogenesis
2.06 4.64e-02 GO:0035113 embryonic appendage morphogenesis

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.29 1.31e-07 GO:0005576 extracellular region
1.69 1.79e-06 GO:0031012 extracellular matrix
1.39 5.50e-06 GO:0044421 extracellular region part
1.16 3.34e-05 GO:0071944 cell periphery
1.16 7.08e-05 GO:0005886 plasma membrane
1.66 8.31e-05 GO:0005578 proteinaceous extracellular matrix
1.23 8.71e-05 GO:0044459 plasma membrane part
2.84 2.29e-03 GO:0005581 collagen
1.96 3.77e-03 GO:0044420 extracellular matrix part
1.27 3.96e-03 GO:0031226 intrinsic to plasma membrane
2.52 5.22e-03 GO:0031093 platelet alpha granule lumen
1.33 7.29e-03 GO:0005615 extracellular space
2.47 7.96e-03 GO:0034774 secretory granule lumen
1.26 8.82e-03 GO:0005887 integral to plasma membrane
2.38 1.05e-02 GO:0031983 vesicle lumen
1.84 1.61e-02 GO:0043292 contractile fiber
2.37 1.76e-02 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
2.23 2.66e-02 GO:0031091 platelet alpha granule
1.07 4.82e-02 GO:0016020 membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
2.27 1.70e-05 GO:0019838 growth factor binding
3.51 1.21e-03 GO:0005520 insulin-like growth factor binding
1.34 4.59e-02 GO:0005509 calcium ion binding