Motif ID: ETS1,2.p2

Z-value: 3.308


Transcription factors associated with ETS1,2.p2:

Gene SymbolEntrez IDGene Name
ETS1 2113 v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
ETS2 2114 v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)



Activity profile for motif ETS1,2.p2.

activity profile for motif ETS1,2.p2


Sorted Z-values histogram for motif ETS1,2.p2

Sorted Z-values for motif ETS1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ETS1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_49562866 5.399 WDFY4
WDFY family member 4
chr1_-_31003260 4.945 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr3_-_184756101 4.891 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr1_-_31003181 4.860 LAPTM5
lysosomal protein transmembrane 5
chr9_-_129707392 4.763 LOC100131355
ST6GALNAC6
hypothetical protein LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr4_+_2783764 4.275 SH3BP2
SH3-domain binding protein 2
chr4_+_2783743 3.927 NM_001145855
SH3BP2
SH3-domain binding protein 2
chr19_-_10311262 3.835 NM_002162
ICAM3
intercellular adhesion molecule 3
chr22_+_35586950 3.709 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr14_+_20319049 3.689 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr16_+_29581783 3.689 NM_001030288
SPN
sialophorin
chr7_+_50318801 3.682 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr3_+_120799411 3.665 NM_015900
PLA1A
phospholipase A1 member A
chr6_-_11490487 3.487 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chrX_+_65152004 3.310


chr3_+_47004457 3.103 NBEAL2
neurobeachin-like 2
chr16_-_29664765 3.093 NM_175900
C16orf54
chromosome 16 open reading frame 54
chr7_-_3049872 3.069 NM_032415
CARD11
caspase recruitment domain family, member 11
chr8_+_75066117 3.006 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr2_-_242205556 2.991 NM_001164356
THAP4
THAP domain containing 4
chr7_-_44985084 2.967 MYO1G
myosin IG
chr21_-_14840506 2.962 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr13_-_45654327 2.961 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr7_-_44985175 2.911 MYO1G
myosin IG
chr1_+_111217244 2.893 NM_000560
CD53
CD53 molecule
chr3_-_13032130 2.844


chr1_-_159306037 2.809 ARHGAP30
Rho GTPase activating protein 30
chr7_-_44985202 2.800 NM_033054
MYO1G
myosin IG
chr9_+_94766379 2.794 FGD3
FYVE, RhoGEF and PH domain containing 3
chr11_+_65164767 2.783 SIPA1
signal-induced proliferation-associated 1
chr19_+_17723285 2.776 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr15_+_79376295 2.741 NM_004513
IL16
interleukin 16 (lymphocyte chemoattractant factor)
chr13_-_45654296 2.727 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_111217314 2.632 CD53
CD53 molecule
chr16_-_49272617 2.626 SNX20
sorting nexin 20
chr13_-_45654292 2.623 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr19_+_16860807 2.612 NM_003950
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr6_+_31661934 2.611 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr10_+_26767698 2.538 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr10_-_98021144 2.488 NM_001114094
NM_013314
BLNK

B-cell linker

chr19_+_17495109 2.481 NM_001098524
NM_173544
FAM129C

family with sequence similarity 129, member C

chr22_-_35875890 2.479 NM_000878
IL2RB
interleukin 2 receptor, beta
chr21_+_25856311 2.471 MIR155HG
MIR155 host gene (non-protein coding)
chr10_+_26767657 2.468 APBB1IP
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr1_-_159306273 2.459 ARHGAP30
Rho GTPase activating protein 30
chr19_+_54530546 2.420 CD37
CD37 molecule
chr1_-_159306210 2.405 ARHGAP30
Rho GTPase activating protein 30
chr5_+_95092384 2.388 NM_014899
RHOBTB3
Rho-related BTB domain containing 3
chr2_-_175170674 2.344 WIPF1
WAS/WASL interacting protein family, member 1
chr2_+_113648020 2.341 NM_012455
PSD4
pleckstrin and Sec7 domain containing 4
chr2_-_96174865 2.335 NM_004418
DUSP2
dual specificity phosphatase 2
chr16_+_30391460 2.319 NM_001114380
NM_002209
ITGAL

integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)

chr22_+_42908589 2.313 NM_001137606
PARVG
parvin, gamma
chr1_+_159899528 2.308 NM_001002273
NM_001002274
NM_001002275
NM_001190828
NM_004001
FCGR2B




FCGR2C
Fc fragment of IgG, low affinity IIb, receptor (CD32)




Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
chr15_+_72861470 2.307 NM_001127190
NM_004383
CSK

c-src tyrosine kinase

chr7_+_150065594 2.258 GIMAP5
GTPase, IMAP family member 5
chr3_-_123223658 2.224 NM_175924
ILDR1
immunoglobulin-like domain containing receptor 1
chr2_+_113648036 2.220 PSD4
pleckstrin and Sec7 domain containing 4
chr17_-_59451662 2.189 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr22_+_42908548 2.188 PARVG
parvin, gamma
chr2_+_130846263 2.170 PTPN18
protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
chr19_+_16860871 2.148 F2RL3
coagulation factor II (thrombin) receptor-like 3
chr22_+_42908612 2.122 PARVG
parvin, gamma
chr19_+_54530512 2.086 CD37
CD37 molecule
chr19_+_54530458 2.053 CD37
CD37 molecule
chr16_+_28413421 2.045 NM_018690
APOBR
apolipoprotein B receptor
chr19_+_54530485 2.034 NM_001040031
NM_001774
CD37

CD37 molecule

chr8_+_56954953 2.018 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr11_+_66927955 2.010 TBC1D10C
TBC1 domain family, member 10C
chr19_+_47073029 2.003 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr19_+_47079089 1.995 NM_004706
NM_198977
ARHGEF1

Rho guanine nucleotide exchange factor (GEF) 1

chr19_+_54530497 1.993 CD37
CD37 molecule
chr1_-_205161821 1.990 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr16_+_30102426 1.978 CORO1A
coronin, actin binding protein, 1A
chr9_-_116190038 1.977 AKNA
AT-hook transcription factor
chr7_-_149960218 1.972 GIMAP6
GTPase, IMAP family member 6
chr10_-_88707299 1.969 NM_024756
MMRN2
multimerin 2
chr10_-_121292139 1.952 NM_001005339
RGS10
regulator of G-protein signaling 10
chr6_-_166676016 1.944 SFT2D1
SFT2 domain containing 1
chr6_-_119137923 1.933 NM_001178035
C6orf204
chromosome 6 open reading frame 204
chr16_+_30391550 1.928 ITGAL
integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr19_+_47079147 1.847 ARHGEF1
Rho guanine nucleotide exchange factor (GEF) 1
chr17_+_18971506 1.847 NM_001129778
GRAPL
GRB2-related adaptor protein-like
chr8_+_56954946 1.846 LYN
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr6_-_166675980 1.834 NM_145169
SFT2D1
SFT2 domain containing 1
chr7_+_73145481 1.828 LIMK1
LIM domain kinase 1
chr22_+_25398690 1.821 LOC388889
hypothetical LOC388889
chr2_-_225519974 1.807 DOCK10
dedicator of cytokinesis 10
chr5_-_149772563 1.804 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr16_+_29582065 1.786 SPN
sialophorin
chr10_+_49563520 1.778 NM_020945
WDFY4
WDFY family member 4
chr7_-_149960612 1.775 NM_024711
GIMAP6
GTPase, IMAP family member 6
chr19_+_59820413 1.769 NM_006669
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr14_-_37795290 1.764 NM_175060
CLEC14A
C-type lectin domain family 14, member A
chr22_-_36212160 1.763 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr9_-_133141726 1.758 NM_033387
FAM78A
family with sequence similarity 78, member A
chr16_+_29582069 1.754 NM_003123
SPN
sialophorin
chr1_-_158883666 1.736 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr1_+_6008956 1.729 NM_003636
NM_172130
KCNAB2

potassium voltage-gated channel, shaker-related subfamily, beta member 2

chr1_+_202000906 1.713 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr1_+_32489426 1.705 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr11_-_71458739 1.671 NUMA1
nuclear mitotic apparatus protein 1
chr8_+_56954899 1.671 NM_001111097
NM_002350
LYN

v-yes-1 Yamaguchi sarcoma viral related oncogene homolog

chr6_+_37081387 1.648 NM_173558
FGD2
FYVE, RhoGEF and PH domain containing 2
chr10_+_31650069 1.643 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr1_-_200395741 1.636 NM_080588
PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr5_+_156625629 1.634 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr11_+_59979857 1.626 NM_021950
NM_152866
MS4A1

membrane-spanning 4-domains, subfamily A, member 1

chr5_-_149772469 1.625 NM_001025159
NM_004355
NM_001025158
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr17_-_40843530 1.620 ARHGAP27
Rho GTPase activating protein 27
chr12_-_56157898 1.618 NM_001080156
ARHGAP9
Rho GTPase activating protein 9
chr1_+_6008999 1.607 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr12_-_53044495 1.603 NM_020370
GPR84
G protein-coupled receptor 84
chr7_+_149779011 1.597 GIMAP8
GTPase, IMAP family member 8
chr9_+_263025 1.585 NM_001190458
NM_001193536
DOCK8

dedicator of cytokinesis 8

chr16_-_30301634 1.574 NM_052838
SEPT1
septin 1
chr11_+_5667494 1.565 NM_006074
TRIM22
tripartite motif containing 22
chr2_-_197883569 1.562 ANKRD44
ankyrin repeat domain 44
chr12_-_47604930 1.543 NM_001143781
FKBP11
FK506 binding protein 11, 19 kDa
chr9_+_139292094 1.524 NM_017723
C9orf167
chromosome 9 open reading frame 167
chr4_-_105631915 1.507 NM_025212
CXXC4
CXXC finger protein 4
chr12_-_6611075 1.507 NM_001142961
LPAR5
lysophosphatidic acid receptor 5
chr11_-_66961709 1.503 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chrX_+_128741578 1.495 SASH3
SAM and SH3 domain containing 3
chr1_-_27825178 1.484 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr4_+_8251818 1.476 NM_018986
SH3TC1
SH3 domain and tetratricopeptide repeats 1
chr3_-_122862447 1.459 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr7_+_150065376 1.452 NM_018384
GIMAP5
GTPase, IMAP family member 5
chr5_-_149772528 1.447


chr1_-_27825633 1.438 NM_001042729
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr16_+_30391609 1.434


chr9_-_122728173 1.432 TRAF1
TNF receptor-associated factor 1
chr3_-_150533948 1.431 NM_001184723
NM_138786
TM4SF18

transmembrane 4 L six family member 18

chr1_-_23376860 1.431 LUZP1
leucine zipper protein 1
chr9_+_68355279 1.426 LOC100132352
FSHD region gene 1 pseudogene
chr14_+_99601498 1.424 NM_016337
EVL
Enah/Vasp-like
chr1_-_181826086 1.419 NCF2
neutrophil cytosolic factor 2
chr22_+_37747063 1.411 NM_152426
APOBEC3D
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
chr11_+_303852 1.407 NM_003641
IFITM1
interferon induced transmembrane protein 1 (9-27)
chr17_-_5078773 1.406 NM_207103
C17orf87
chromosome 17 open reading frame 87
chr19_-_13074973 1.406 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr12_-_6103945 1.405 NM_000552
VWF
von Willebrand factor
chr16_+_3295433 1.404 NM_153028
ZNF75A
zinc finger protein 75a
chr2_+_143603368 1.403 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr8_+_11388918 1.398 NM_001715
BLK
B lymphoid tyrosine kinase
chr12_-_64849998 1.395 TMBIM4
transmembrane BAX inhibitor motif containing 4
chr12_-_101396459 1.385 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chrX_+_128741562 1.382 NM_018990
SASH3
SAM and SH3 domain containing 3
chr1_-_19998955 1.382 NM_181719
TMCO4
transmembrane and coiled-coil domains 4
chr14_-_37795001 1.372 CLEC14A
C-type lectin domain family 14, member A
chr4_-_38710376 1.371 NM_024943
TMEM156
transmembrane protein 156
chr2_+_143603439 1.366 ARHGAP15
Rho GTPase activating protein 15
chr20_-_23014828 1.366 NM_012072
CD93
CD93 molecule
chr17_-_1495742 1.362 NM_003693
NM_145350
NM_145352
SCARF1


scavenger receptor class F, member 1


chr11_+_65164963 1.361


chr16_-_3295375 1.361


chr3_-_122862391 1.360 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr9_-_129656413 1.359 ENG
endoglin
chr15_+_79080341 1.348 NM_022566
MESDC1
mesoderm development candidate 1
chr15_+_72861767 1.344 CSK
c-src tyrosine kinase
chr14_-_22354457 1.344 SLC7A7
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr22_-_16080265 1.336 CECR1
cat eye syndrome chromosome region, candidate 1
chr2_+_109112428 1.335 NM_001099289
SH3RF3
SH3 domain containing ring finger 3
chr7_+_73262283 1.333 LAT2
linker for activation of T cells family, member 2
chr3_+_188197029 1.321


chr12_+_91620749 1.320 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chrX_-_130792297 1.316 LOC286467
hypothetical LOC286467
chr14_+_99601517 1.313 EVL
Enah/Vasp-like
chr17_+_1906262 1.303 NM_001098202
HIC1
hypermethylated in cancer 1
chr17_-_3766708 1.293 NM_002558
P2RX1
purinergic receptor P2X, ligand-gated ion channel, 1
chr12_+_74160779 1.293 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr10_-_98470164 1.288 NM_152309
PIK3AP1
phosphoinositide-3-kinase adaptor protein 1
chr9_+_68116254 1.276 LOC100132352
LOC642236
FSHD region gene 1 pseudogene
FSHD region gene 1 pseudogene
chr17_-_35975227 1.269 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr11_-_66967838 1.267 NM_001018070
CORO1B
coronin, actin binding protein, 1B
chr22_+_36008511 1.262 CYTH4
cytohesin 4
chr18_+_59767567 1.261 NM_001123366
HMSD
histocompatibility (minor) serpin domain containing
chr11_+_5667392 1.258 TRIM22
tripartite motif containing 22
chr7_-_5535726 1.258 ACTB
actin, beta
chr19_-_6432765 1.255 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr7_+_73262188 1.252 LAT2
linker for activation of T cells family, member 2
chr21_-_45165249 1.246 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr5_+_180582905 1.243 NM_033549
NM_201627
TRIM41

tripartite motif containing 41

chr13_+_110653407 1.242 ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr16_-_49272741 1.241 NM_001144972
NM_153337
NM_182854
SNX20


sorting nexin 20


chr11_-_67528103 1.233 NM_030930
UNC93B1
unc-93 homolog B1 (C. elegans)
chr16_+_48857962 1.232 ADCY7
adenylate cyclase 7
chr21_-_45165302 1.229 NM_000211
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr19_-_61324412 1.225 ZNF787
zinc finger protein 787
chr2_-_96174502 1.221 DUSP2
dual specificity phosphatase 2
chr2_-_175207521 1.220 NM_003387
WIPF1
WAS/WASL interacting protein family, member 1
chr8_-_21827057 1.211 NM_003974
DOK2
docking protein 2, 56kDa
chr17_-_18890963 1.208 NM_006613
GRAP
GRB2-related adaptor protein
chr22_-_35970230 1.207 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr19_-_43800374 1.204 NM_001042600
NM_007181
MAP4K1

mitogen-activated protein kinase kinase kinase kinase 1

chr5_+_180582880 1.204 TRIM41
tripartite motif containing 41
chr1_+_208008517 1.199 TRAF3IP3
TRAF3 interacting protein 3
chr22_-_35970133 1.198 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr19_-_18058632 1.198 NM_005535
NM_153701
IL12RB1

interleukin 12 receptor, beta 1

chr14_+_102313585 1.197 TRAF3
TNF receptor-associated factor 3

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.88 4.01e-11 GO:0001775 cell activation
1.16 6.31e-09 GO:0050794 regulation of cellular process
1.48 7.95e-09 GO:0002376 immune system process
1.14 3.90e-08 GO:0065007 biological regulation
1.14 1.66e-07 GO:0050789 regulation of biological process
2.04 7.57e-07 GO:0045321 leukocyte activation
2.14 2.46e-06 GO:0046649 lymphocyte activation
1.21 3.73e-05 GO:0031323 regulation of cellular metabolic process
1.53 3.84e-05 GO:0002682 regulation of immune system process
1.31 3.97e-05 GO:0048583 regulation of response to stimulus
2.74 5.55e-05 GO:0042113 B cell activation
1.19 1.25e-04 GO:0019222 regulation of metabolic process
1.64 1.32e-04 GO:0050776 regulation of immune response
1.94 1.43e-04 GO:0051249 regulation of lymphocyte activation
1.90 1.71e-04 GO:0030168 platelet activation
1.20 2.33e-04 GO:0080090 regulation of primary metabolic process
1.87 2.81e-04 GO:0002694 regulation of leukocyte activation
1.23 3.24e-04 GO:0048518 positive regulation of biological process
2.03 3.48e-04 GO:0051251 positive regulation of lymphocyte activation
1.47 3.59e-04 GO:0006955 immune response
1.62 4.75e-04 GO:0002684 positive regulation of immune system process
1.17 5.57e-04 GO:0044260 cellular macromolecule metabolic process
1.97 5.66e-04 GO:0050867 positive regulation of cell activation
1.82 6.49e-04 GO:0050865 regulation of cell activation
1.96 7.47e-04 GO:0002696 positive regulation of leukocyte activation
1.28 9.62e-04 GO:0006464 protein modification process
1.19 1.18e-03 GO:0060255 regulation of macromolecule metabolic process
1.94 1.50e-03 GO:0002764 immune response-regulating signaling pathway
1.19 1.52e-03 GO:0016043 cellular component organization
1.23 1.74e-03 GO:0048522 positive regulation of cellular process
2.32 1.82e-03 GO:0050851 antigen receptor-mediated signaling pathway
2.23 1.91e-03 GO:0002768 immune response-regulating cell surface receptor signaling pathway
1.26 1.93e-03 GO:0043412 macromolecule modification
2.11 2.29e-03 GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
1.24 2.60e-03 GO:0051252 regulation of RNA metabolic process
1.93 3.44e-03 GO:0050863 regulation of T cell activation
1.18 3.64e-03 GO:0071840 cellular component organization or biogenesis
1.91 3.91e-03 GO:0002757 immune response-activating signal transduction
1.24 4.09e-03 GO:0006355 regulation of transcription, DNA-dependent
1.22 4.33e-03 GO:0010556 regulation of macromolecule biosynthetic process
1.20 5.04e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.22 5.22e-03 GO:0006950 response to stress
2.01 5.37e-03 GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade
1.18 5.51e-03 GO:0007165 signal transduction
2.03 5.67e-03 GO:0050870 positive regulation of T cell activation
2.20 5.75e-03 GO:0002429 immune response-activating cell surface receptor signaling pathway
1.52 7.39e-03 GO:0007596 blood coagulation
1.52 7.39e-03 GO:0050817 coagulation
1.60 8.59e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.20 9.27e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21 9.60e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.21 1.00e-02 GO:0010468 regulation of gene expression
1.51 1.03e-02 GO:0007599 hemostasis
1.70 1.08e-02 GO:0010740 positive regulation of intracellular protein kinase cascade
1.29 1.27e-02 GO:0035556 intracellular signal transduction
1.15 1.63e-02 GO:0051716 cellular response to stimulus
2.14 1.67e-02 GO:0032944 regulation of mononuclear cell proliferation
1.13 1.74e-02 GO:0043170 macromolecule metabolic process
3.90 1.96e-02 GO:0050853 B cell receptor signaling pathway
1.26 2.43e-02 GO:0006996 organelle organization
1.19 2.51e-02 GO:0009889 regulation of biosynthetic process
1.19 2.70e-02 GO:0031326 regulation of cellular biosynthetic process
1.99 2.71e-02 GO:0002521 leukocyte differentiation
1.49 2.74e-02 GO:0070271 protein complex biogenesis
2.14 2.92e-02 GO:0030098 lymphocyte differentiation
2.47 3.29e-02 GO:0050864 regulation of B cell activation
1.49 3.40e-02 GO:0006461 protein complex assembly
2.08 3.51e-02 GO:0070663 regulation of leukocyte proliferation
2.10 3.64e-02 GO:0050670 regulation of lymphocyte proliferation
1.06 3.89e-02 GO:0009987 cellular process
1.45 4.06e-02 GO:0050878 regulation of body fluid levels
1.57 4.57e-02 GO:0018193 peptidyl-amino acid modification

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.06 2.84e-04 GO:0005622 intracellular
1.06 4.39e-04 GO:0044424 intracellular part
1.26 1.56e-02 GO:0005654 nucleoplasm
1.11 1.60e-02 GO:0005634 nucleus

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.17 7.59e-12 GO:0005515 protein binding
1.06 4.04e-04 GO:0005488 binding
1.83 1.59e-02 GO:0005085 guanyl-nucleotide exchange factor activity
1.46 1.75e-02 GO:0060589 nucleoside-triphosphatase regulator activity