Motif ID: TFDP1.p2

Z-value: 1.676


Transcription factors associated with TFDP1.p2:

Gene SymbolEntrez IDGene Name
TFDP1 7027 transcription factor Dp-1



Activity profile for motif TFDP1.p2.

activity profile for motif TFDP1.p2


Sorted Z-values histogram for motif TFDP1.p2

Sorted Z-values for motif TFDP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFDP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_80125514 4.120 MEX3B
mex-3 homolog B (C. elegans)
chr19_+_16296734 3.861 KLF2
Kruppel-like factor 2 (lung)
chr13_-_109236897 3.741 NM_003749
IRS2
insulin receptor substrate 2
chr15_-_80125403 3.718 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr10_+_23768203 3.701 NM_001145373
OTUD1
OTU domain containing 1
chr15_-_81667169 3.366 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr3_+_160964574 3.181 SCHIP1
schwannomin interacting protein 1
chr19_+_39664706 2.923 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr19_+_16296632 2.787 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chr1_+_6767968 2.673 NM_001195563
NM_015215
CAMTA1

calmodulin binding transcription activator 1

chr21_+_37661063 2.648 DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr4_+_38341982 2.544 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr4_+_89147821 2.536 NM_000297
PKD2
polycystic kidney disease 2 (autosomal dominant)
chr18_+_12298242 2.502 NM_032525
TUBB6
tubulin, beta 6
chr20_+_8997791 2.352 PLCB4
phospholipase C, beta 4
chr10_-_126839546 2.347 NM_001083914
CTBP2
C-terminal binding protein 2
chr10_-_126839056 2.296 NM_001329
CTBP2
C-terminal binding protein 2
chr16_+_12902955 2.291 NM_001145204
NM_001145205
SHISA9

shisa homolog 9 (Xenopus laevis)

chr22_-_20419975 2.290 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr2_-_45090025 2.202 NM_016932
SIX2
SIX homeobox 2
chr10_-_131652007 2.167 NM_001005463
EBF3
early B-cell factor 3
chr19_-_45888259 2.145 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr11_+_12652427 2.117 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr9_+_81377419 2.102 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr16_-_53520208 2.071 CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr3_+_51403760 2.065 NM_013286
RBM15B
RNA binding motif protein 15B
chr22_-_35113876 2.046 MYH9
myosin, heavy chain 9, non-muscle
chr9_-_13269562 2.045 MPDZ
multiple PDZ domain protein
chr19_+_38979502 2.033 NM_001129994
NM_001129995
NM_024076
KCTD15


potassium channel tetramerisation domain containing 15


chr15_-_81667773 2.030 HDGFRP3
hepatoma-derived growth factor, related protein 3
chr2_-_144991386 2.027 ZEB2
zinc finger E-box binding homeobox 2
chr5_+_60663842 2.015 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr17_+_52026058 2.008 NM_005450
NOG
noggin
chr10_-_126839000 1.975 CTBP2
C-terminal binding protein 2
chr18_-_21184824 1.951


chr16_+_85158357 1.927 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr9_+_127549437 1.910 NM_006195
PBX3
pre-B-cell leukemia homeobox 3
chr10_-_131652364 1.890 EBF3
early B-cell factor 3
chr1_+_26671548 1.874 HMGN2
high-mobility group nucleosomal binding domain 2
chr11_-_66945190 1.863 PPP1CA
protein phosphatase 1, catalytic subunit, alpha isozyme
chr2_-_160972606 1.854 RBMS1
RNA binding motif, single stranded interacting protein 1
chr8_-_80842452 1.850 NM_001040708
NM_012258
HEY1

hairy/enhancer-of-split related with YRPW motif 1

chr6_-_112301123 1.837 NM_002037
FYN
FYN oncogene related to SRC, FGR, YES
chr20_+_8997660 1.830 NM_001172646
PLCB4
phospholipase C, beta 4
chr7_+_98084531 1.799 NM_002523
NPTX2
neuronal pentraxin II
chr14_+_99775185 1.790 YY1
YY1 transcription factor
chr11_+_35596310 1.772 NM_014344
FJX1
four jointed box 1 (Drosophila)
chr4_-_57671273 1.764 NM_001553
IGFBP7
insulin-like growth factor binding protein 7
chr2_-_183611470 1.742 NM_013436
NM_205842
NCKAP1

NCK-associated protein 1

chr4_+_3434830 1.739 NM_001164673
NM_173660
DOK7

docking protein 7

chr22_-_35113923 1.734 MYH9
myosin, heavy chain 9, non-muscle
chr15_-_27901828 1.726 NM_003257
NM_175610
TJP1

tight junction protein 1 (zona occludens 1)

chr11_-_109672401 1.722 NM_002906
RDX
radixin
chr22_-_35113947 1.706 MYH9
myosin, heavy chain 9, non-muscle
chr13_-_100125028 1.702 TMTC4
transmembrane and tetratricopeptide repeat containing 4
chr6_-_35764655 1.701 NM_001145776
NM_001145777
NM_004117
FKBP5


FK506 binding protein 5


chr2_+_28469864 1.693 FOSL2
FOS-like antigen 2
chr22_-_35113797 1.672 MYH9
myosin, heavy chain 9, non-muscle
chr10_+_129595289 1.667 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chr13_+_72531098 1.659 NM_001730
KLF5
Kruppel-like factor 5 (intestinal)
chr17_+_27838041 1.655 NM_003885
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr16_-_71650034 1.653 NM_001164766
ZFHX3
zinc finger homeobox 3
chr1_+_64012154 1.649 NM_001083592
NM_005012
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr4_+_3264509 1.645 RGS12
regulator of G-protein signaling 12
chr13_-_29067795 1.640 NM_003045
SLC7A1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr16_+_53522611 1.636 NM_005853
IRX5
iroquois homeobox 5
chrX_-_101073632 1.633 NM_001011657
ZMAT1
zinc finger, matrin-type 1
chr2_+_242146791 1.629 NM_032515
BOK
BCL2-related ovarian killer
chr9_+_81377289 1.617 TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr7_-_148212312 1.614 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr7_-_148212310 1.601 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr20_-_30534848 1.595 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr7_-_148212292 1.589 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr9_-_122516399 1.588 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr7_-_525556 1.587 PDGFA
platelet-derived growth factor alpha polypeptide
chr7_-_525336 1.584 PDGFA
platelet-derived growth factor alpha polypeptide
chr9_-_109291575 1.571 KLF4
Kruppel-like factor 4 (gut)
chr7_-_148212336 1.552 NM_004456
NM_152998
EZH2

enhancer of zeste homolog 2 (Drosophila)

chr18_+_12298236 1.545 TUBB6
tubulin, beta 6
chr6_-_85530617 1.544 NM_001080508
TBX18
T-box 18
chr6_-_91063181 1.543 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr9_-_16860719 1.539 NM_017637
BNC2
basonuclin 2
chr13_-_105985313 1.539 NM_004093
EFNB2
ephrin-B2
chr1_+_109827975 1.504 NM_153340
ATXN7L2
ataxin 7-like 2
chr6_-_35764588 1.502 FKBP5
FK506 binding protein 5
chr9_-_79835970 1.499 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr18_+_12298189 1.490 TUBB6
tubulin, beta 6
chr4_-_57671307 1.483 IGFBP7
insulin-like growth factor binding protein 7
chr20_+_59260847 1.469 NM_001794
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr7_+_30140868 1.468 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr7_-_148212230 1.464 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr12_-_48387233 1.452


chr4_+_145786622 1.450 NM_022475
HHIP
hedgehog interacting protein
chr8_+_95977135 1.443 C8orf38
chromosome 8 open reading frame 38
chr7_+_90731671 1.434 NM_003505
FZD1
frizzled homolog 1 (Drosophila)
chr6_+_20510019 1.430 NM_001949
E2F3
E2F transcription factor 3
chr6_-_86409415 1.428 SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr13_-_20533703 1.426 NM_014572
LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr5_+_10617431 1.425 NM_001164440
ANKRD33B
ankyrin repeat domain 33B
chr10_+_124210980 1.412 NM_002775
HTRA1
HtrA serine peptidase 1
chr11_+_66381451 1.411 NM_024036
LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr13_-_25523164 1.409 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr4_-_57671112 1.403 IGFBP7
insulin-like growth factor binding protein 7
chr3_+_137167153 1.402 NM_001190447
NM_002718
PPP2R3A

protein phosphatase 2, regulatory subunit B'', alpha

chr9_-_35062596 1.401 VCP
valosin containing protein
chr4_-_174326880 1.393


chr17_-_39652391 1.392 UBTF
upstream binding transcription factor, RNA polymerase I
chr9_+_89302239 1.379 DAPK1
death-associated protein kinase 1
chr9_-_72218098 1.368 KLF9
Kruppel-like factor 9
chr1_-_40140126 1.365 NM_001033081
NM_001033082
NM_005376
MYCL1


v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)


chr22_-_35114001 1.362 NM_002473
MYH9
myosin, heavy chain 9, non-muscle
chr19_+_59333287 1.357 CNOT3
CCR4-NOT transcription complex, subunit 3
chr9_-_35062545 1.355 VCP
valosin containing protein
chr9_-_135923373 1.353 BRD3
bromodomain containing 3
chr1_+_196392513 1.351 NM_133494
NEK7
NIMA (never in mitosis gene a)-related kinase 7
chr7_+_148026819 1.341 NM_003592
CUL1
cullin 1
chr12_-_105056577 1.341 NUAK1
NUAK family, SNF1-like kinase, 1
chrX_-_129072333 1.340 NM_001127197
ELF4
E74-like factor 4 (ets domain transcription factor)
chr2_+_28469850 1.330 FOSL2
FOS-like antigen 2
chr10_+_123862430 1.329 TACC2
transforming, acidic coiled-coil containing protein 2
chr17_-_59131210 1.327 NM_030576
LIMD2
LIM domain containing 2
chr7_-_5535726 1.312 ACTB
actin, beta
chr2_+_241023880 1.310


chr22_+_47263919 1.307 NM_001082967
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr16_-_87378872 1.301 NM_001142864
FAM38A
family with sequence similarity 38, member A
chr15_-_59308770 1.299 NM_134261
RORA
RAR-related orphan receptor A
chr8_-_125453815 1.292 TMEM65
transmembrane protein 65
chr15_-_59308708 1.292 RORA
RAR-related orphan receptor A
chr15_-_27901628 1.289 TJP1
tight junction protein 1 (zona occludens 1)
chr3_+_137167296 1.288 PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr12_-_41269679 1.288 NM_153026
PRICKLE1
prickle homolog 1 (Drosophila)
chr4_-_1683712 1.285 NM_006527
SLBP
stem-loop binding protein
chr14_-_29466562 1.275 NM_002742
PRKD1
protein kinase D1
chr6_-_33864883 1.273 NM_181336
LEMD2
LEM domain containing 2
chr15_+_81567327 1.271 NM_001144903
NM_023003
TM6SF1

transmembrane 6 superfamily member 1

chr4_+_174326464 1.266 NM_017423
GALNT7
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr7_-_526005 1.266 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr12_-_95317928 1.243 CDK17
cyclin-dependent kinase 17
chr13_-_40138607 1.241 NM_002015
FOXO1
forkhead box O1
chr14_+_99507848 1.240 EVL
Enah/Vasp-like
chr1_-_95165089 1.239 NM_001839
CNN3
calponin 3, acidic
chr19_-_44032415 1.237 HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr5_+_177564102 1.226 NM_004499
NM_031266
HNRNPAB

heterogeneous nuclear ribonucleoprotein A/B

chr5_+_34692352 1.218 NM_001145520
RAI14
retinoic acid induced 14
chr2_-_175255717 1.213 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr9_-_35062578 1.211 VCP
valosin containing protein
chr19_-_37588281 1.211 LOC400684
hypothetical LOC400684
chr19_+_59333232 1.210 NM_014516
CNOT3
CCR4-NOT transcription complex, subunit 3
chr5_+_34692124 1.206 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr2_+_23461802 1.203 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chr20_+_55718619 1.192


chr5_+_177564139 1.190 HNRNPAB
heterogeneous nuclear ribonucleoprotein A/B
chr21_-_39607288 1.189 BRWD1
bromodomain and WD repeat domain containing 1
chr10_+_129595349 1.189 PTPRE
protein tyrosine phosphatase, receptor type, E
chr20_-_55718351 1.187 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chr10_+_42953886 1.186 NM_018590
CSGALNACT2
chondroitin sulfate N-acetylgalactosaminyltransferase 2
chr8_+_38763911 1.185 TACC1
transforming, acidic coiled-coil containing protein 1
chr17_-_39652449 1.180 NM_001076684
UBTF
upstream binding transcription factor, RNA polymerase I
chr8_-_101803338 1.179 PABPC1
poly(A) binding protein, cytoplasmic 1
chr1_-_232811846 1.178 NM_001077397
NM_182972
IRF2BP2

interferon regulatory factor 2 binding protein 2

chr9_+_107046758 1.172 SLC44A1
solute carrier family 44, member 1
chr19_+_627346 1.167 NM_005860
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr12_-_48387394 1.167 FMNL3
formin-like 3
chr15_-_58671929 1.164 NM_134262
RORA
RAR-related orphan receptor A
chr8_-_125454097 1.163 NM_194291
TMEM65
transmembrane protein 65
chr1_-_226202210 1.160 NM_003395
WNT9A
wingless-type MMTV integration site family, member 9A
chr2_+_176702667 1.158 NM_019558
HOXD8
homeobox D8
chr15_+_90738108 1.154 NM_006011
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr13_+_30672087 1.147 NM_194318
B3GALTL
beta 1,3-galactosyltransferase-like
chr1_-_68071635 1.146 NM_018841
GNG12
guanine nucleotide binding protein (G protein), gamma 12
chr8_+_61753793 1.145 NM_017780
CHD7
chromodomain helicase DNA binding protein 7
chr2_-_1727292 1.142 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr2_-_144991556 1.142 ZEB2
zinc finger E-box binding homeobox 2
chr17_-_39211706 1.136 NM_004090
DUSP3
dual specificity phosphatase 3
chr9_+_107046713 1.135 NM_080546
SLC44A1
solute carrier family 44, member 1
chr4_+_146622154 1.134 NM_005900
SMAD1
SMAD family member 1
chr13_+_30672122 1.132 B3GALTL
beta 1,3-galactosyltransferase-like
chr9_-_137938778 1.125 NM_015447
CAMSAP1
calmodulin regulated spectrin-associated protein 1
chr9_-_133605037 1.123 RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr1_-_23367918 1.123 LUZP1
leucine zipper protein 1
chr9_-_16860664 1.120 BNC2
basonuclin 2
chr3_+_38470782 1.119 NM_001106
ACVR2B
activin A receptor, type IIB
chr1_-_5975068 1.119 NM_015102
NPHP4
nephronophthisis 4
chr10_+_76256305 1.115 NM_012330
MYST4
MYST histone acetyltransferase (monocytic leukemia) 4
chr1_-_19155360 1.109 NM_001136265
IFFO2
intermediate filament family orphan 2
chr5_-_142763481 1.107 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr14_+_105028614 1.104 NM_001134875
NM_001134876
C14orf80

chromosome 14 open reading frame 80

chr5_-_142763393 1.097 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr7_+_44802691 1.097 NM_021130
PPIA
peptidylprolyl isomerase A (cyclophilin A)
chr8_-_101803489 1.096 NM_002568
PABPC1
poly(A) binding protein, cytoplasmic 1
chr9_+_138680064 1.093 EGFL7
EGF-like-domain, multiple 7
chr4_-_86106567 1.090 NM_014991
WDFY3
WD repeat and FYVE domain containing 3
chrX_-_129072103 1.089 ELF4
E74-like factor 4 (ets domain transcription factor)
chr2_+_85213884 1.085 NM_031283
TCF7L1
transcription factor 7-like 1 (T-cell specific, HMG-box)
chr15_+_54998181 1.085 TCF12
transcription factor 12
chr14_-_99842519 1.085 NM_001039355
SLC25A29
solute carrier family 25, member 29
chr2_-_1727247 1.084 PXDN
peroxidasin homolog (Drosophila)
chr3_+_180348818 1.083 NM_006218
PIK3CA
phosphoinositide-3-kinase, catalytic, alpha polypeptide
chr17_+_7728819 1.083 NM_001005271
CHD3
chromodomain helicase DNA binding protein 3
chr7_-_138316393 1.082 NM_001164665
NM_020910
KIAA1549

KIAA1549


Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.30 3.61e-48 GO:0044260 cellular macromolecule metabolic process
1.12 2.15e-45 GO:0009987 cellular process
1.22 1.60e-43 GO:0044237 cellular metabolic process
1.23 3.62e-34 GO:0043170 macromolecule metabolic process
1.19 1.22e-32 GO:0044238 primary metabolic process
1.17 3.73e-32 GO:0008152 metabolic process
1.31 2.70e-28 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.35 7.86e-28 GO:0090304 nucleic acid metabolic process
1.26 3.04e-23 GO:0034641 cellular nitrogen compound metabolic process
1.25 9.68e-23 GO:0006807 nitrogen compound metabolic process
1.35 1.68e-21 GO:0016070 RNA metabolic process
1.27 3.71e-21 GO:0071841 cellular component organization or biogenesis at cellular level
1.24 4.33e-21 GO:0016043 cellular component organization
1.28 4.88e-21 GO:0071842 cellular component organization at cellular level
1.23 1.98e-20 GO:0071840 cellular component organization or biogenesis
1.33 2.05e-20 GO:0006464 protein modification process
1.35 3.55e-20 GO:0034645 cellular macromolecule biosynthetic process
1.35 3.92e-20 GO:0009059 macromolecule biosynthetic process
1.27 1.22e-19 GO:0044267 cellular protein metabolic process
1.31 4.89e-19 GO:0043412 macromolecule modification
1.14 7.37e-19 GO:0050794 regulation of cellular process
1.32 2.05e-18 GO:0010467 gene expression
1.26 1.65e-16 GO:0044249 cellular biosynthetic process
1.12 4.87e-16 GO:0050789 regulation of biological process
1.44 2.66e-15 GO:0006351 transcription, DNA-dependent
1.20 7.17e-15 GO:0031323 regulation of cellular metabolic process
1.24 7.36e-15 GO:0009058 biosynthetic process
1.20 9.11e-15 GO:0080090 regulation of primary metabolic process
1.40 4.48e-14 GO:0032774 RNA biosynthetic process
1.11 4.55e-14 GO:0065007 biological regulation
1.39 5.11e-14 GO:0007049 cell cycle
1.20 7.24e-14 GO:0060255 regulation of macromolecule metabolic process
1.30 2.37e-13 GO:0006996 organelle organization
1.23 3.71e-13 GO:0048522 positive regulation of cellular process
1.17 7.18e-12 GO:0019222 regulation of metabolic process
1.21 2.14e-11 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.68 5.15e-11 GO:0032446 protein modification by small protein conjugation
1.20 7.67e-11 GO:0048518 positive regulation of biological process
1.20 1.94e-10 GO:0051171 regulation of nitrogen compound metabolic process
1.19 2.24e-10 GO:0019538 protein metabolic process
1.59 5.23e-10 GO:0070647 protein modification by small protein conjugation or removal
1.21 6.92e-10 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.20 1.06e-09 GO:0010468 regulation of gene expression
1.34 1.13e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.42 1.82e-09 GO:0051726 regulation of cell cycle
1.66 1.97e-09 GO:0016567 protein ubiquitination
1.21 2.07e-09 GO:0051252 regulation of RNA metabolic process
1.31 4.99e-09 GO:0008104 protein localization
1.20 6.82e-09 GO:0048519 negative regulation of biological process
1.21 7.63e-09 GO:0048523 negative regulation of cellular process
1.28 1.14e-08 GO:0033036 macromolecule localization
1.36 1.17e-08 GO:0022402 cell cycle process
1.18 1.84e-08 GO:0031326 regulation of cellular biosynthetic process
1.18 1.86e-08 GO:0009889 regulation of biosynthetic process
1.19 1.87e-08 GO:0010556 regulation of macromolecule biosynthetic process
1.26 3.32e-08 GO:0009966 regulation of signal transduction
1.40 3.79e-08 GO:0051276 chromosome organization
1.25 6.89e-08 GO:0007399 nervous system development
1.34 8.78e-08 GO:0051128 regulation of cellular component organization
1.40 1.63e-07 GO:0000278 mitotic cell cycle
1.23 3.21e-07 GO:0023051 regulation of signaling
1.19 3.94e-07 GO:0006355 regulation of transcription, DNA-dependent
1.37 5.96e-07 GO:0007167 enzyme linked receptor protein signaling pathway
1.34 7.57e-07 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.48 9.59e-07 GO:0016568 chromatin modification
1.37 9.60e-07 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.43 9.95e-07 GO:0006325 chromatin organization
1.30 1.22e-06 GO:0022008 neurogenesis
1.35 1.23e-06 GO:0022403 cell cycle phase
1.31 1.50e-06 GO:0048699 generation of neurons
1.33 1.52e-06 GO:0051173 positive regulation of nitrogen compound metabolic process
1.40 1.52e-06 GO:0016071 mRNA metabolic process
1.26 1.81e-06 GO:0031325 positive regulation of cellular metabolic process
1.34 2.56e-06 GO:0009890 negative regulation of biosynthetic process
1.30 3.08e-06 GO:0045184 establishment of protein localization
1.40 3.45e-06 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.35 3.76e-06 GO:0010558 negative regulation of macromolecule biosynthetic process
1.29 4.03e-06 GO:0010605 negative regulation of macromolecule metabolic process
1.59 4.83e-06 GO:0048011 nerve growth factor receptor signaling pathway
1.35 5.12e-06 GO:0006396 RNA processing
1.45 5.70e-06 GO:0006397 mRNA processing
1.30 6.12e-06 GO:0015031 protein transport
1.34 6.44e-06 GO:0031327 negative regulation of cellular biosynthetic process
1.24 6.59e-06 GO:0009893 positive regulation of metabolic process
1.27 8.36e-06 GO:0032268 regulation of cellular protein metabolic process
1.30 9.44e-06 GO:0033554 cellular response to stress
1.35 1.26e-05 GO:0010629 negative regulation of gene expression
1.46 1.45e-05 GO:0051301 cell division
1.37 1.48e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.22 1.69e-05 GO:0009653 anatomical structure morphogenesis
1.25 2.01e-05 GO:0010604 positive regulation of macromolecule metabolic process
1.50 2.08e-05 GO:0006366 transcription from RNA polymerase II promoter
1.33 2.17e-05 GO:0051254 positive regulation of RNA metabolic process
1.23 2.22e-05 GO:0051641 cellular localization
1.35 2.62e-05 GO:0000902 cell morphogenesis
1.36 2.66e-05 GO:0051253 negative regulation of RNA metabolic process
1.32 2.85e-05 GO:0030182 neuron differentiation
1.34 3.25e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37 3.48e-05 GO:0034613 cellular protein localization
1.26 3.70e-05 GO:0009892 negative regulation of metabolic process
1.37 3.92e-05 GO:0070727 cellular macromolecule localization
1.34 3.96e-05 GO:0006259 DNA metabolic process
1.25 4.18e-05 GO:0022607 cellular component assembly
1.29 4.53e-05 GO:0046907 intracellular transport
1.31 4.55e-05 GO:0065003 macromolecular complex assembly
1.44 5.18e-05 GO:0044419 interspecies interaction between organisms
1.26 5.35e-05 GO:0006793 phosphorus metabolic process
1.26 5.35e-05 GO:0006796 phosphate metabolic process
1.27 5.80e-05 GO:0031324 negative regulation of cellular metabolic process
1.37 6.96e-05 GO:0031175 neuron projection development
1.33 7.29e-05 GO:0032989 cellular component morphogenesis
1.25 7.44e-05 GO:0051246 regulation of protein metabolic process
1.32 8.00e-05 GO:0030030 cell projection organization
1.33 8.10e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
1.27 8.38e-05 GO:0008219 cell death
1.28 8.47e-05 GO:0043933 macromolecular complex subunit organization
1.23 9.53e-05 GO:0044085 cellular component biogenesis
1.27 1.06e-04 GO:0016265 death
1.46 1.13e-04 GO:0008380 RNA splicing
1.21 1.13e-04 GO:0035556 intracellular signal transduction
1.36 1.15e-04 GO:0006974 response to DNA damage stimulus
1.36 1.23e-04 GO:0000904 cell morphogenesis involved in differentiation
1.48 1.35e-04 GO:0010608 posttranscriptional regulation of gene expression
1.46 1.50e-04 GO:0048285 organelle fission
1.27 1.57e-04 GO:0031328 positive regulation of cellular biosynthetic process
2.48 1.82e-04 GO:0010717 regulation of epithelial to mesenchymal transition
1.45 2.22e-04 GO:0000087 M phase of mitotic cell cycle
1.27 2.45e-04 GO:0009891 positive regulation of biosynthetic process
1.29 2.73e-04 GO:0012501 programmed cell death
1.45 3.40e-04 GO:0000280 nuclear division
1.45 3.40e-04 GO:0007067 mitosis
1.32 4.45e-04 GO:0048666 neuron development
1.31 5.57e-04 GO:0045893 positive regulation of transcription, DNA-dependent
1.22 5.92e-04 GO:0044248 cellular catabolic process
1.36 6.15e-04 GO:0048812 neuron projection morphogenesis
1.28 6.81e-04 GO:0006915 apoptosis
1.29 7.10e-04 GO:0010628 positive regulation of gene expression
1.29 7.32e-04 GO:0019220 regulation of phosphate metabolic process
1.29 7.32e-04 GO:0051174 regulation of phosphorus metabolic process
1.38 7.70e-04 GO:0009968 negative regulation of signal transduction
1.37 8.00e-04 GO:0007409 axonogenesis
1.29 9.15e-04 GO:0045595 regulation of cell differentiation
1.27 9.96e-04 GO:0071844 cellular component assembly at cellular level
1.52 1.10e-03 GO:0000375 RNA splicing, via transesterification reactions
1.33 1.11e-03 GO:0032990 cell part morphogenesis
1.27 1.17e-03 GO:0016192 vesicle-mediated transport
1.33 1.36e-03 GO:0048858 cell projection morphogenesis
1.33 1.67e-03 GO:0034621 cellular macromolecular complex subunit organization
1.35 1.78e-03 GO:0000279 M phase
1.35 1.97e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
1.52 2.09e-03 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
1.52 2.09e-03 GO:0000398 nuclear mRNA splicing, via spliceosome
1.39 2.10e-03 GO:0010564 regulation of cell cycle process
1.21 2.20e-03 GO:0051649 establishment of localization in cell
1.10 2.34e-03 GO:0051716 cellular response to stimulus
1.43 2.51e-03 GO:0001944 vasculature development
1.28 2.64e-03 GO:0042325 regulation of phosphorylation
1.31 2.92e-03 GO:0044265 cellular macromolecule catabolic process
1.11 2.97e-03 GO:0051179 localization
1.38 3.03e-03 GO:0018193 peptidyl-amino acid modification
1.25 3.04e-03 GO:0031399 regulation of protein modification process
1.36 3.41e-03 GO:0007264 small GTPase mediated signal transduction
1.52 3.90e-03 GO:0016569 covalent chromatin modification
1.11 3.90e-03 GO:0032502 developmental process
1.39 4.86e-03 GO:0007411 axon guidance
1.26 4.90e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.38 5.11e-03 GO:0006281 DNA repair
1.22 5.38e-03 GO:0032879 regulation of localization
1.11 6.43e-03 GO:0007165 signal transduction
1.28 6.60e-03 GO:0001932 regulation of protein phosphorylation
1.52 6.67e-03 GO:0016570 histone modification
1.25 7.01e-03 GO:0006468 protein phosphorylation
1.36 7.77e-03 GO:0034622 cellular macromolecular complex assembly
1.23 8.12e-03 GO:0048468 cell development
1.28 8.27e-03 GO:0009057 macromolecule catabolic process
1.60 9.55e-03 GO:0048705 skeletal system morphogenesis
1.39 9.85e-03 GO:0051325 interphase
1.37 1.08e-02 GO:0045597 positive regulation of cell differentiation
1.32 1.11e-02 GO:0010648 negative regulation of cell communication
1.11 1.11e-02 GO:0048856 anatomical structure development
1.79 1.12e-02 GO:0007173 epidermal growth factor receptor signaling pathway
1.66 1.15e-02 GO:0010720 positive regulation of cell development
1.18 1.15e-02 GO:0009056 catabolic process
1.35 1.20e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.31 1.28e-02 GO:0043549 regulation of kinase activity
1.30 1.39e-02 GO:0006461 protein complex assembly
1.30 1.48e-02 GO:0051338 regulation of transferase activity
1.32 1.49e-02 GO:0023057 negative regulation of signaling
1.30 1.51e-02 GO:0070271 protein complex biogenesis
1.29 1.56e-02 GO:0010942 positive regulation of cell death
1.59 1.70e-02 GO:0006403 RNA localization
1.41 1.74e-02 GO:0001568 blood vessel development
1.12 1.84e-02 GO:0048731 system development
1.31 1.92e-02 GO:0045859 regulation of protein kinase activity
1.29 2.11e-02 GO:0043065 positive regulation of apoptosis
1.22 2.27e-02 GO:0050793 regulation of developmental process
1.46 2.40e-02 GO:0001701 in utero embryonic development
2.46 2.65e-02 GO:0010770 positive regulation of cell morphogenesis involved in differentiation
1.22 2.67e-02 GO:0016310 phosphorylation
1.37 3.00e-02 GO:0051329 interphase of mitotic cell cycle
1.34 3.05e-02 GO:0009792 embryo development ending in birth or egg hatching
1.28 3.55e-02 GO:0043068 positive regulation of programmed cell death
1.43 3.59e-02 GO:0045786 negative regulation of cell cycle
1.34 3.69e-02 GO:0006917 induction of apoptosis
1.37 3.69e-02 GO:0051130 positive regulation of cellular component organization
1.33 3.73e-02 GO:0043009 chordate embryonic development
1.36 3.88e-02 GO:0060284 regulation of cell development
1.29 3.96e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.32 4.09e-02 GO:0006886 intracellular protein transport
1.16 4.36e-02 GO:0065009 regulation of molecular function
1.34 4.54e-02 GO:0012502 induction of programmed cell death
1.10 4.58e-02 GO:0007275 multicellular organismal development
1.57 4.84e-02 GO:0050657 nucleic acid transport
1.57 4.84e-02 GO:0050658 RNA transport
1.57 4.84e-02 GO:0051236 establishment of RNA localization

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.15 3.65e-87 GO:0005622 intracellular
1.16 1.76e-85 GO:0044424 intracellular part
1.19 2.67e-67 GO:0043227 membrane-bounded organelle
1.19 1.41e-66 GO:0043231 intracellular membrane-bounded organelle
1.17 3.34e-66 GO:0043226 organelle
1.17 2.65e-65 GO:0043229 intracellular organelle
1.25 1.02e-52 GO:0005634 nucleus
1.16 4.19e-41 GO:0005737 cytoplasm
1.39 2.04e-37 GO:0044428 nuclear part
1.21 8.37e-36 GO:0044446 intracellular organelle part
1.21 1.55e-35 GO:0044422 organelle part
1.41 3.30e-33 GO:0031981 nuclear lumen
1.34 3.22e-29 GO:0070013 intracellular organelle lumen
1.32 3.08e-27 GO:0031974 membrane-enclosed lumen
1.33 3.57e-27 GO:0043233 organelle lumen
1.17 2.22e-26 GO:0044444 cytoplasmic part
1.05 1.28e-25 GO:0044464 cell part
1.05 1.51e-25 GO:0005623 cell
1.41 8.68e-24 GO:0005654 nucleoplasm
1.31 3.89e-21 GO:0005829 cytosol
1.20 8.04e-17 GO:0032991 macromolecular complex
1.22 3.30e-15 GO:0043228 non-membrane-bounded organelle
1.22 3.30e-15 GO:0043232 intracellular non-membrane-bounded organelle
1.44 1.03e-13 GO:0044451 nucleoplasm part
1.20 2.64e-13 GO:0043234 protein complex
1.41 8.03e-09 GO:0005694 chromosome
1.37 9.15e-09 GO:0015630 microtubule cytoskeleton
1.41 3.00e-07 GO:0044427 chromosomal part
1.47 1.08e-06 GO:0005815 microtubule organizing center
1.20 3.41e-06 GO:0012505 endomembrane system
1.17 6.64e-06 GO:0031090 organelle membrane
1.35 1.39e-05 GO:0005730 nucleolus
1.47 1.55e-04 GO:0005635 nuclear envelope
1.25 2.16e-04 GO:0031982 vesicle
1.31 3.52e-04 GO:0030529 ribonucleoprotein complex
1.25 4.26e-04 GO:0031410 cytoplasmic vesicle
1.45 4.69e-04 GO:0000785 chromatin
1.46 6.68e-04 GO:0016604 nuclear body
1.57 7.70e-04 GO:0031965 nuclear membrane
1.51 9.93e-04 GO:0031252 cell leading edge
1.46 1.14e-03 GO:0000228 nuclear chromosome
1.17 1.22e-03 GO:0005856 cytoskeleton
1.24 2.33e-03 GO:0031988 membrane-bounded vesicle
1.69 2.78e-03 GO:0042470 melanosome
1.69 2.78e-03 GO:0048770 pigment granule
1.43 3.29e-03 GO:0005813 centrosome
1.24 3.39e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.52 4.79e-03 GO:0005912 adherens junction
1.19 7.42e-03 GO:0044430 cytoskeletal part
1.51 1.12e-02 GO:0000793 condensed chromosome
1.64 1.14e-02 GO:0016585 chromatin remodeling complex
1.91 1.73e-02 GO:0017053 transcriptional repressor complex
1.22 1.88e-02 GO:0031975 envelope
1.22 2.18e-02 GO:0031967 organelle envelope
1.42 2.77e-02 GO:0005819 spindle
1.18 3.03e-02 GO:0005794 Golgi apparatus
1.72 3.39e-02 GO:0000123 histone acetyltransferase complex
1.48 4.87e-02 GO:0005681 spliceosomal complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.20 3.80e-51 GO:0005515 protein binding
1.10 5.77e-35 GO:0005488 binding
1.21 1.29e-16 GO:0003676 nucleic acid binding
1.24 1.69e-14 GO:0000166 nucleotide binding
1.33 9.81e-11 GO:0030528 transcription regulator activity
1.21 3.14e-10 GO:0003677 DNA binding
1.12 1.03e-09 GO:0003824 catalytic activity
1.66 1.55e-09 GO:0019787 small conjugating protein ligase activity
1.36 2.51e-09 GO:0019899 enzyme binding
1.34 3.10e-09 GO:0003723 RNA binding
1.67 4.32e-09 GO:0004842 ubiquitin-protein ligase activity
1.58 3.16e-08 GO:0016881 acid-amino acid ligase activity
1.54 5.69e-08 GO:0016879 ligase activity, forming carbon-nitrogen bonds
1.28 3.02e-07 GO:0001071 nucleic acid binding transcription factor activity
1.28 3.02e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
1.20 3.09e-07 GO:0035639 purine ribonucleoside triphosphate binding
1.20 3.83e-07 GO:0017076 purine nucleotide binding
1.20 4.15e-07 GO:0032553 ribonucleotide binding
1.20 4.15e-07 GO:0032555 purine ribonucleotide binding
1.41 1.16e-06 GO:0016874 ligase activity
1.20 3.00e-06 GO:0016740 transferase activity
1.27 4.72e-06 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.46 1.06e-05 GO:0016563 transcription activator activity
1.40 5.82e-05 GO:0000988 protein binding transcription factor activity
1.40 5.82e-05 GO:0000989 transcription factor binding transcription factor activity
1.39 8.24e-05 GO:0003712 transcription cofactor activity
1.28 1.26e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.27 1.40e-04 GO:0016301 kinase activity
1.18 1.65e-04 GO:0030554 adenyl nucleotide binding
1.19 2.08e-04 GO:0005524 ATP binding
1.18 2.23e-04 GO:0032559 adenyl ribonucleotide binding
1.83 2.65e-04 GO:0031625 ubiquitin protein ligase binding
1.28 2.94e-04 GO:0043565 sequence-specific DNA binding
1.33 3.12e-04 GO:0060589 nucleoside-triphosphatase regulator activity
1.34 3.45e-04 GO:0030695 GTPase regulator activity
1.34 7.71e-04 GO:0019904 protein domain specific binding
1.49 2.56e-03 GO:0003682 chromatin binding
1.36 7.98e-03 GO:0016564 transcription repressor activity
1.88 8.35e-03 GO:0019903 protein phosphatase binding
2.90 1.25e-02 GO:0070411 I-SMAD binding
1.36 1.32e-02 GO:0005083 small GTPase regulator activity
1.25 1.38e-02 GO:0004672 protein kinase activity
1.93 1.69e-02 GO:0046332 SMAD binding
1.35 1.84e-02 GO:0008134 transcription factor binding
1.50 2.36e-02 GO:0008022 protein C-terminus binding
1.40 3.40e-02 GO:0003713 transcription coactivator activity
1.28 3.68e-02 GO:0004674 protein serine/threonine kinase activity
1.29 4.53e-02 GO:0008047 enzyme activator activity