Motif ID: PATZ1.p2

Z-value: 3.212


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1



Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_34114924 8.379 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr17_+_34115383 4.023 NM_005937
MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr2_-_25328452 3.813 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr11_+_63829616 3.666 NM_004451
ESRRA
estrogen-related receptor alpha
chr1_-_32574185 3.614 NM_023009
MARCKSL1
MARCKS-like 1
chr17_-_73636386 3.597 NM_001127198
TMC6
transmembrane channel-like 6
chr17_-_73636362 3.502 TMC6
transmembrane channel-like 6
chr19_-_4017739 3.408 NM_015898
ZBTB7A
zinc finger and BTB domain containing 7A
chr8_+_144706699 3.145 NM_001166237
GSDMD
gasdermin D
chrX_+_138060 3.089 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr9_-_125732005 3.061 NM_020946
NM_024820
DENND1A

DENN/MADD domain containing 1A

chrX_+_9392980 2.894 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr1_+_3679168 2.799 NM_001163724
LOC388588
hypothetical protein LOC388588
chr19_-_55524445 2.676 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr19_+_61344501 2.671 ZNF444
zinc finger protein 444
chr16_+_29725311 2.654 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr16_+_87047159 2.616 ZFPM1
zinc finger protein, multitype 1
chr6_+_34313007 2.539 HMGA1
high mobility group AT-hook 1
chr12_+_100615530 2.484 NM_020244
CHPT1
choline phosphotransferase 1
chr6_+_34312979 2.458 HMGA1
high mobility group AT-hook 1
chr19_+_8180179 2.457 NM_024552
LASS4
LAG1 homolog, ceramide synthase 4
chr7_-_100077072 2.448 NM_003227
TFR2
transferrin receptor 2
chr19_+_34994701 2.410 NM_001238
CCNE1
cyclin E1
chr19_+_61344341 2.393 NM_018337
ZNF444
zinc finger protein 444
chr9_+_70509925 2.384 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr10_+_124885556 2.383 NM_001105574
HMX3
H6 family homeobox 3
chr14_-_21064182 2.356 SALL2
sal-like 2 (Drosophila)
chr22_+_20101661 2.354 NM_015094
HIC2
hypermethylated in cancer 2
chr17_+_52688842 2.341 NM_138962
MSI2
musashi homolog 2 (Drosophila)
chr2_+_170298700 2.307 KLHL23
kelch-like 23 (Drosophila)
chr5_+_176446425 2.271 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr9_-_122679387 2.270 NM_001009936
NM_015651
PHF19

PHD finger protein 19

chr20_+_34635362 2.264 NM_021809
TGIF2
TGFB-induced factor homeobox 2
chr22_-_18807805 2.260 PI4KAP2
PI4KAP1
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 2
phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
chr17_-_71352090 2.233 UNC13D
unc-13 homolog D (C. elegans)
chr17_+_44429748 2.212 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr20_+_61841662 2.210 SLC2A4RG
SLC2A4 regulator
chr17_-_34015631 2.207 NM_025248
SRCIN1
SRC kinase signaling inhibitor 1
chr11_+_117812282 2.164 NM_001197104
NM_005933
MLL

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)

chr19_+_7891193 2.136 NM_003083
SNAPC2
small nuclear RNA activating complex, polypeptide 2, 45kDa
chr10_+_102719239 2.065 SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr1_-_21868380 2.063 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr6_+_7052798 2.050 NM_001168344
RREB1
ras responsive element binding protein 1
chr7_-_100325209 2.043 NM_001015072
UFSP1
UFM1-specific peptidase 1 (non-functional)
chr22_-_17545872 2.040 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr17_+_73676219 2.033 NM_004710
SYNGR2
synaptogyrin 2
chr6_+_34313347 2.019 HMGA1
high mobility group AT-hook 1
chr2_-_171725150 2.019 TLK1
tousled-like kinase 1
chr3_-_13436725 2.010 NUP210
nucleoporin 210kDa
chr16_+_29725597 2.000


chr17_-_71352017 2.000 UNC13D
unc-13 homolog D (C. elegans)
chr14_-_37134191 2.000 NM_004496
FOXA1
forkhead box A1
chr2_+_170298487 1.992


chr2_-_32089608 1.986 MEMO1
mediator of cell motility 1
chr22_-_17546296 1.984 NM_005984
SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr2_-_32089557 1.977 MEMO1
mediator of cell motility 1
chr6_-_32265489 1.969 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chr11_+_63758550 1.941 NM_003377
VEGFB
vascular endothelial growth factor B
chr2_+_218972963 1.904 NM_182642
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr19_+_13090101 1.904 NM_052876
NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr12_+_56202874 1.902 NM_052897
MBD6
methyl-CpG binding domain protein 6
chr22_-_17546234 1.897 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr20_+_61841553 1.889 NM_020062
SLC2A4RG
SLC2A4 regulator
chr5_+_139008667 1.871 CXXC5
CXXC finger protein 5
chr3_-_13436802 1.855 NM_024923
NUP210
nucleoporin 210kDa
chr16_+_1979959 1.854 NM_004209
SYNGR3
synaptogyrin 3
chr19_-_14062230 1.848 NM_138352
SAMD1
sterile alpha motif domain containing 1
chr19_+_18069596 1.847 NM_015016
MAST3
microtubule associated serine/threonine kinase 3
chr15_+_78232184 1.821 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr22_-_21231421 1.811 NM_206955
NM_206956
NM_006115
NM_206953
NM_206954
PRAME




preferentially expressed antigen in melanoma




chr9_+_139566129 1.805 NM_032477
MRPL41
mitochondrial ribosomal protein L41
chr17_+_75366524 1.796 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr16_+_88422354 1.777 NM_032451
SPIRE2
spire homolog 2 (Drosophila)
chr12_+_54910767 1.765 NM_001135195
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr19_+_59064795 1.759 MYADM
myeloid-associated differentiation marker
chr2_-_61551403 1.757 USP34
ubiquitin specific peptidase 34
chr1_+_26895108 1.757 NM_006015
NM_139135
ARID1A

AT rich interactive domain 1A (SWI-like)

chr2_-_174537354 1.747 SP3
Sp3 transcription factor
chr8_+_27404508 1.727 NM_001979
EPHX2
epoxide hydrolase 2, cytoplasmic
chr22_-_17546276 1.702 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr7_-_158073121 1.693 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr17_-_71352182 1.688 NM_199242
UNC13D
unc-13 homolog D (C. elegans)
chr2_+_219779737 1.678 NM_138802
ZFAND2B
zinc finger, AN1-type domain 2B
chr19_-_16868674 1.675 CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr1_-_233879617 1.673 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr17_+_38186141 1.672 NM_032387
WNK4
WNK lysine deficient protein kinase 4
chr20_+_30409649 1.672 NM_001164603
NM_015338
ASXL1

additional sex combs like 1 (Drosophila)

chr4_+_1764802 1.661 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr15_+_38520594 1.660 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr15_+_78232232 1.651 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr22_+_38183480 1.649 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr1_+_111963920 1.633 NM_001010935
NM_002884
RAP1A

RAP1A, member of RAS oncogene family

chr17_-_77094426 1.625 ACTG1
actin, gamma 1
chr17_-_77094375 1.621 NM_001614
ACTG1
actin, gamma 1
chr20_-_62181231 1.619 NM_005873
RGS19
regulator of G-protein signaling 19
chr16_+_66676833 1.600 NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr7_-_103417198 1.594 NM_005045
NM_173054
RELN

reelin

chr15_+_78232160 1.593 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr14_-_90953883 1.592 NM_001080414
CCDC88C
coiled-coil domain containing 88C
chr9_-_115178969 1.590 HDHD3
haloacid dehalogenase-like hydrolase domain containing 3
chr7_-_150283794 1.586 NM_172057
KCNH2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr7_-_154425510 1.577 NM_007349
PAXIP1
PAX interacting (with transcription-activation domain) protein 1
chr6_+_41622267 1.572 FOXP4
forkhead box P4
chr10_+_76256305 1.564 NM_012330
MYST4
MYST histone acetyltransferase (monocytic leukemia) 4
chr21_-_37260488 1.559 HLCS
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr15_+_78232194 1.556 FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr12_-_123914375 1.547 NM_001082959
NM_005505
SCARB1

scavenger receptor class B, member 1

chr16_+_29725665 1.526


chr5_-_134397740 1.515 NM_002653
PITX1
paired-like homeodomain 1
chr20_+_31783426 1.511 NM_032819
ZNF341
zinc finger protein 341
chr21_+_43267760 1.509 PKNOX1
PBX/knotted 1 homeobox 1
chr20_+_30813851 1.499 NM_006892
NM_175848
NM_175849
DNMT3B


DNA (cytosine-5-)-methyltransferase 3 beta


chr2_-_32089309 1.494 MEMO1
mediator of cell motility 1
chr17_+_26060617 1.488


chr2_-_32089226 1.487 MEMO1
mediator of cell motility 1
chr21_+_46473494 1.474 MCM3AP-AS1
MCM3AP antisense RNA 1 (non-protein coding)
chr19_-_14177980 1.470 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr19_-_53950458 1.457 NM_000148
FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr11_+_550868 1.449 NM_001143993
RASSF7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr2_+_112529270 1.444 NM_032824
TMEM87B
transmembrane protein 87B
chr1_+_945331 1.443 NM_198576
AGRN
agrin
chr19_-_50688310 1.440 NM_206901
RTN2
reticulon 2
chr12_+_56621711 1.440 NM_033276
XRCC6BP1
XRCC6 binding protein 1
chr12_-_123914219 1.437 SCARB1
scavenger receptor class B, member 1
chr1_+_172104115 1.434 NM_001122770
NM_032522
ZBTB37

zinc finger and BTB domain containing 37

chr22_-_22440054 1.431 NM_213720
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr7_+_151792052 1.426 LOC100128822
hypothetical LOC100128822
chr16_-_1369613 1.421 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr20_+_35407872 1.420 NM_198291
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr20_+_30410447 1.417 ASXL1
additional sex combs like 1 (Drosophila)
chr19_-_44034797 1.417 NM_001005335
HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr6_+_41622111 1.411 NM_001012426
NM_001012427
NM_138457
FOXP4


forkhead box P4


chr15_-_20637731 1.406 NM_144599
NIPA1
non imprinted in Prader-Willi/Angelman syndrome 1
chr11_+_46358909 1.406 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr7_+_101860958 1.404 NM_001126340
NM_032831
ORAI2

ORAI calcium release-activated calcium modulator 2

chr9_+_94860828 1.396 SUSD3
sushi domain containing 3
chr9_+_94860769 1.390 NM_145006
SUSD3
sushi domain containing 3
chr5_+_139008209 1.383 NM_016463
CXXC5
CXXC finger protein 5
chr6_-_31977747 1.382 NM_181842
ZBTB12
zinc finger and BTB domain containing 12
chr7_-_156378382 1.376 LMBR1
limb region 1 homolog (mouse)
chr16_+_87047418 1.371 NM_153813
ZFPM1
zinc finger protein, multitype 1
chr6_+_169866714 1.371 LOC729088
hypothetical LOC729088
chr16_-_88295595 1.370 NM_152339
SPATA2L
spermatogenesis associated 2-like
chr9_+_114288899 1.368 NM_133465
KIAA1958
KIAA1958
chr12_-_123914299 1.368 SCARB1
scavenger receptor class B, member 1
chr9_+_114289178 1.362 KIAA1958
KIAA1958
chr10_-_75241347 1.361 NDST2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr16_+_88542639 1.360 NM_017702
NM_207514
DEF8

differentially expressed in FDCP 8 homolog (mouse)

chr7_+_137795719 1.359 TRIM24
tripartite motif containing 24
chr20_-_3102169 1.357 ProSAPiP1
ProSAPiP1 protein
chr3_+_185580554 1.353 NM_003741
CHRD
chordin
chr17_-_20886680 1.350 NM_015276
USP22
ubiquitin specific peptidase 22
chr21_-_43369492 1.350 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chr7_+_101861007 1.348 ORAI2
ORAI calcium release-activated calcium modulator 2
chr19_+_40223249 1.348 NM_002151
NM_182983
HPN

hepsin

chr17_-_39632845 1.339 ATXN7L3
ataxin 7-like 3
chr20_+_60906605 1.337 NM_007346
OGFR
opioid growth factor receptor
chr7_+_149696901 1.334 REPIN1
replication initiator 1
chr4_-_6253152 1.330 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr17_-_53946899 1.324 MTMR4
myotubularin related protein 4
chr16_-_30014993 1.320 NM_031477
NM_001145524
YPEL3

yippee-like 3 (Drosophila)

chr6_+_149680747 1.314 TAB2
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr2_+_218972721 1.312 NM_021198
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr6_+_7052985 1.312 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chr22_-_49042065 1.311 NM_002969
MAPK12
mitogen-activated protein kinase 12
chr5_-_176671897 1.307 NM_001142935
NM_031300
MXD3

MAX dimerization protein 3

chr19_+_40900965 1.305 MLL4
myeloid/lymphoid or mixed-lineage leukemia 4
chr12_-_61614930 1.300 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr20_+_30814048 1.297 DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr20_-_48980858 1.291 NM_015339
NM_181442
ADNP

activity-dependent neuroprotector homeobox

chr19_+_10404110 1.290 NM_001111309
PDE4A
phosphodiesterase 4A, cAMP-specific
chr19_+_40224457 1.290 HPN
hepsin
chr12_+_49443903 1.285 NM_005171
ATF1
activating transcription factor 1
chr22_+_18081968 1.283 NM_002688
SEPT5
septin 5
chr2_+_10101081 1.280 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr1_-_158334983 1.278 NM_052868
IGSF8
immunoglobulin superfamily, member 8
chr11_-_64268841 1.277 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr16_+_66676851 1.276 NM_004555
NM_173163
NM_173164
NM_173165
NFATC3



nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3



chr1_-_41480368 1.273 SCMH1
sex comb on midleg homolog 1 (Drosophila)
chr16_+_2503915 1.272 ATP6V0C
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
chr20_+_61839931 1.271 LIME1
Lck interacting transmembrane adaptor 1
chr2_+_233927880 1.270 NM_152879
DGKD
diacylglycerol kinase, delta 130kDa
chr2_-_61551350 1.270 NM_014709
USP34
ubiquitin specific peptidase 34
chr18_+_11971421 1.268 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr7_-_150305933 1.264 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr14_+_74964261 1.263 NM_001135047
JDP2
Jun dimerization protein 2
chr6_+_11646472 1.257 NM_001100829
TMEM170B
transmembrane protein 170B
chr19_+_59064471 1.257 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr11_-_72170533 1.257 STARD10
StAR-related lipid transfer (START) domain containing 10
chr20_-_24986501 1.251 ACSS1
acyl-CoA synthetase short-chain family member 1
chr16_+_49139694 1.251 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr20_-_31737815 1.242 NM_005225
E2F1
E2F transcription factor 1
chr6_+_34312906 1.239 HMGA1
high mobility group AT-hook 1
chr12_+_110328126 1.238 NM_005475
SH2B3
SH2B adaptor protein 3
chr11_-_72141064 1.228 NM_001040118
ARAP1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr2_+_233927892 1.226 DGKD
diacylglycerol kinase, delta 130kDa
chr11_-_16992524 1.226 NM_175058
PLEKHA7
pleckstrin homology domain containing, family A member 7
chr1_+_90059992 1.220 NM_018103
LRRC8D
leucine rich repeat containing 8 family, member D
chr14_+_101297887 1.219 NM_001161725
NM_001161726
PPP2R5C

protein phosphatase 2, regulatory subunit B', gamma

chr19_-_2653662 1.203 GNG7
guanine nucleotide binding protein (G protein), gamma 7

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.08 2.69e-24 GO:0009987 cellular process
1.16 1.28e-17 GO:0044260 cellular macromolecule metabolic process
1.13 7.39e-17 GO:0044237 cellular metabolic process
1.59 2.32e-15 GO:0016568 chromatin modification
1.17 2.78e-13 GO:0016043 cellular component organization
1.16 1.07e-12 GO:0031323 regulation of cellular metabolic process
1.16 3.00e-12 GO:0080090 regulation of primary metabolic process
1.16 5.27e-12 GO:0071840 cellular component organization or biogenesis
1.16 1.85e-11 GO:0060255 regulation of macromolecule metabolic process
1.10 4.87e-11 GO:0050794 regulation of cellular process
1.10 6.43e-11 GO:0044238 primary metabolic process
1.09 6.87e-11 GO:0008152 metabolic process
1.12 1.28e-10 GO:0043170 macromolecule metabolic process
1.08 3.39e-10 GO:0065007 biological regulation
1.18 4.21e-10 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.18 5.02e-10 GO:0071842 cellular component organization at cellular level
1.18 5.30e-10 GO:0010468 regulation of gene expression
1.21 6.21e-10 GO:0006464 protein modification process
1.17 6.69e-10 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.17 7.91e-10 GO:0051171 regulation of nitrogen compound metabolic process
1.19 8.31e-10 GO:0051252 regulation of RNA metabolic process
1.14 9.70e-10 GO:0019222 regulation of metabolic process
1.17 1.04e-09 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.18 1.75e-09 GO:0010556 regulation of macromolecule biosynthetic process
1.09 1.98e-09 GO:0050789 regulation of biological process
1.19 3.85e-09 GO:0048523 negative regulation of cellular process
1.16 5.83e-09 GO:0071841 cellular component organization or biogenesis at cellular level
1.66 5.84e-09 GO:0016569 covalent chromatin modification
1.66 9.06e-09 GO:0016570 histone modification
1.41 1.16e-08 GO:0006325 chromatin organization
1.20 1.29e-08 GO:0043412 macromolecule modification
1.18 1.82e-08 GO:0006355 regulation of transcription, DNA-dependent
1.21 2.10e-08 GO:0006996 organelle organization
1.17 2.62e-08 GO:0048519 negative regulation of biological process
1.16 3.09e-08 GO:0031326 regulation of cellular biosynthetic process
1.16 3.71e-08 GO:0009889 regulation of biosynthetic process
1.34 1.27e-07 GO:0051276 chromosome organization
1.14 1.53e-07 GO:0034641 cellular nitrogen compound metabolic process
1.27 1.57e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.14 1.57e-07 GO:0006807 nitrogen compound metabolic process
1.33 1.88e-07 GO:0010558 negative regulation of macromolecule biosynthetic process
1.17 2.07e-07 GO:0090304 nucleic acid metabolic process
1.33 3.05e-07 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.25 6.81e-07 GO:0007049 cell cycle
1.27 7.31e-07 GO:0010605 negative regulation of macromolecule metabolic process
1.31 7.93e-07 GO:0009890 negative regulation of biosynthetic process
1.33 8.70e-07 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27 9.05e-07 GO:0031324 negative regulation of cellular metabolic process
1.32 1.75e-06 GO:0051172 negative regulation of nitrogen compound metabolic process
1.30 2.25e-06 GO:0031327 negative regulation of cellular biosynthetic process
1.15 2.79e-06 GO:0044267 cellular protein metabolic process
1.34 4.46e-06 GO:0051253 negative regulation of RNA metabolic process
1.25 4.89e-06 GO:0009892 negative regulation of metabolic process
1.34 5.35e-06 GO:0045892 negative regulation of transcription, DNA-dependent
1.20 6.71e-06 GO:0007399 nervous system development
1.15 9.03e-06 GO:0048522 positive regulation of cellular process
1.30 1.20e-05 GO:0051726 regulation of cell cycle
1.30 3.24e-05 GO:0010629 negative regulation of gene expression
1.12 7.29e-05 GO:0048856 anatomical structure development
1.24 1.12e-04 GO:0006351 transcription, DNA-dependent
1.25 1.27e-04 GO:0022402 cell cycle process
1.18 1.62e-04 GO:0009966 regulation of signal transduction
1.13 1.78e-04 GO:0048518 positive regulation of biological process
1.12 2.72e-04 GO:0048731 system development
1.16 2.86e-04 GO:0034645 cellular macromolecule biosynthetic process
1.20 4.10e-04 GO:0010604 positive regulation of macromolecule metabolic process
1.16 4.25e-04 GO:0016070 RNA metabolic process
1.21 4.35e-04 GO:0032268 regulation of cellular protein metabolic process
1.15 4.63e-04 GO:0030154 cell differentiation
1.16 6.48e-04 GO:0009059 macromolecule biosynthetic process
1.20 7.78e-04 GO:0051246 regulation of protein metabolic process
1.10 1.21e-03 GO:0032502 developmental process
1.74 1.70e-03 GO:0006338 chromatin remodeling
1.32 1.80e-03 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.14 1.83e-03 GO:0048869 cellular developmental process
1.18 2.28e-03 GO:0009893 positive regulation of metabolic process
1.12 2.34e-03 GO:0044249 cellular biosynthetic process
1.38 2.38e-03 GO:0032446 protein modification by small protein conjugation
1.10 2.48e-03 GO:0007275 multicellular organismal development
1.18 2.68e-03 GO:0031325 positive regulation of cellular metabolic process
1.21 3.65e-03 GO:0048699 generation of neurons
1.15 3.70e-03 GO:0023051 regulation of signaling
1.22 4.53e-03 GO:0031399 regulation of protein modification process
1.30 5.53e-03 GO:0009968 negative regulation of signal transduction
1.12 6.01e-03 GO:0009058 biosynthetic process
1.41 6.53e-03 GO:0051259 protein oligomerization
1.23 6.87e-03 GO:0022403 cell cycle phase
1.32 8.80e-03 GO:0010564 regulation of cell cycle process
1.33 1.10e-02 GO:0070647 protein modification by small protein conjugation or removal
1.37 1.10e-02 GO:0016567 protein ubiquitination
1.30 1.95e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.26 2.35e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.28 2.46e-02 GO:0032583 regulation of gene-specific transcription
1.19 2.70e-02 GO:0048468 cell development
1.22 3.11e-02 GO:0009790 embryo development
1.27 3.47e-02 GO:0010648 negative regulation of cell communication
1.19 3.81e-02 GO:0022008 neurogenesis
1.18 3.90e-02 GO:0032774 RNA biosynthetic process
1.20 4.02e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34 4.10e-02 GO:0007346 regulation of mitotic cell cycle
1.22 4.17e-02 GO:0051254 positive regulation of RNA metabolic process
1.27 4.46e-02 GO:0023057 negative regulation of signaling

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.10 6.10e-41 GO:0044424 intracellular part
1.10 1.02e-40 GO:0005622 intracellular
1.12 9.44e-34 GO:0043227 membrane-bounded organelle
1.12 2.41e-33 GO:0043231 intracellular membrane-bounded organelle
1.10 1.57e-30 GO:0043226 organelle
1.10 1.98e-30 GO:0043229 intracellular organelle
1.17 2.61e-29 GO:0005634 nucleus
1.26 1.53e-20 GO:0044428 nuclear part
1.10 2.55e-19 GO:0005737 cytoplasm
1.27 8.88e-18 GO:0031981 nuclear lumen
1.23 4.28e-16 GO:0070013 intracellular organelle lumen
1.22 5.37e-16 GO:0043233 organelle lumen
1.21 7.32e-15 GO:0031974 membrane-enclosed lumen
1.27 5.99e-13 GO:0005654 nucleoplasm
1.12 7.80e-13 GO:0044446 intracellular organelle part
1.11 2.42e-12 GO:0044422 organelle part
1.19 1.44e-10 GO:0005829 cytosol
1.10 1.77e-09 GO:0044444 cytoplasmic part
1.30 8.14e-08 GO:0044451 nucleoplasm part
1.02 1.01e-05 GO:0005623 cell
1.30 1.10e-05 GO:0005694 chromosome
1.48 1.14e-05 GO:0000228 nuclear chromosome
1.02 1.19e-05 GO:0044464 cell part
1.50 5.93e-05 GO:0044454 nuclear chromosome part
1.73 6.82e-05 GO:0000790 nuclear chromatin
1.68 1.03e-04 GO:0016585 chromatin remodeling complex
1.30 1.29e-04 GO:0044427 chromosomal part
1.11 2.72e-04 GO:0043234 protein complex
1.38 1.90e-03 GO:0000785 chromatin
1.09 4.69e-03 GO:0032991 macromolecular complex
1.86 7.28e-03 GO:0000781 chromosome, telomeric region
2.22 1.04e-02 GO:0031519 PcG protein complex
1.33 3.49e-02 GO:0016604 nuclear body
1.75 4.10e-02 GO:0017053 transcriptional repressor complex

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 4.36e-30 GO:0005515 protein binding
1.08 1.57e-29 GO:0005488 binding
1.17 3.07e-13 GO:0003676 nucleic acid binding
1.20 3.41e-12 GO:0003677 DNA binding
1.32 4.13e-09 GO:0019899 enzyme binding
1.27 6.19e-09 GO:0030528 transcription regulator activity
1.30 2.57e-07 GO:0043565 sequence-specific DNA binding
1.24 1.20e-06 GO:0001071 nucleic acid binding transcription factor activity
1.24 1.20e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.17 5.74e-06 GO:0016740 transferase activity
1.24 6.20e-06 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.14 7.87e-06 GO:0000166 nucleotide binding
1.26 9.06e-06 GO:0016301 kinase activity
1.41 1.12e-05 GO:0016564 transcription repressor activity
1.41 1.79e-05 GO:0008134 transcription factor binding
1.48 5.16e-05 GO:0000975 regulatory region DNA binding
1.48 5.16e-05 GO:0001067 regulatory region nucleic acid binding
1.48 5.16e-05 GO:0044212 transcription regulatory region DNA binding
1.49 5.25e-05 GO:0010843 promoter binding
1.14 9.71e-05 GO:0008270 zinc ion binding
1.37 1.32e-04 GO:0016563 transcription activator activity
1.24 2.34e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.08 3.08e-04 GO:0003824 catalytic activity
1.39 6.33e-04 GO:0003702 RNA polymerase II transcription factor activity
1.12 1.38e-03 GO:0046914 transition metal ion binding
1.09 2.61e-03 GO:0043169 cation binding
1.28 2.80e-03 GO:0019904 protein domain specific binding
1.09 2.98e-03 GO:0043167 ion binding
1.09 3.72e-03 GO:0046872 metal ion binding
1.67 5.43e-03 GO:0042393 histone binding
1.41 7.13e-03 GO:0003682 chromatin binding
1.13 8.13e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.23 8.34e-03 GO:0004672 protein kinase activity
1.12 8.79e-03 GO:0032553 ribonucleotide binding
1.12 8.79e-03 GO:0032555 purine ribonucleotide binding
1.14 1.07e-02 GO:0032559 adenyl ribonucleotide binding
1.12 1.17e-02 GO:0017076 purine nucleotide binding
1.14 1.19e-02 GO:0030554 adenyl nucleotide binding
1.14 1.59e-02 GO:0005524 ATP binding
1.35 1.85e-02 GO:0019787 small conjugating protein ligase activity
1.27 2.91e-02 GO:0003712 transcription cofactor activity
1.27 3.59e-02 GO:0000988 protein binding transcription factor activity
1.27 3.59e-02 GO:0000989 transcription factor binding transcription factor activity
1.25 3.89e-02 GO:0004674 protein serine/threonine kinase activity
1.60 4.59e-02 GO:0047485 protein N-terminus binding