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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: RREB1.p2

Z-value: 2.851

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_-_96924582	9.248	NM_001172667	FAM178B	family with sequence similarity 178, member B
chr1_-_30977931	5.770		LAPTM5	lysosomal protein transmembrane 5
chrX_+_151617900	4.243	NM_005363 NM_175868	MAGEA6	melanoma antigen family A, 6
chrX_-_151688850	3.953	NM_005362	MAGEA3	melanoma antigen family A, 3
chr11_-_74740298	3.647	NM_004041 NM_020251	ARRB1	arrestin, beta 1
chr17_-_44058612	3.100	NM_024017	HOXB9	homeobox B9
chr17_-_73636386	3.033	NM_001127198	TMC6	transmembrane channel-like 6
chr17_-_73636362	2.796		TMC6	transmembrane channel-like 6
chr14_+_28305922	2.734	NM_005249	FOXG1	forkhead box G1
chr20_+_48032918	2.673	NM_005985	SNAI1	snail homolog 1 (Drosophila)
chr22_-_21231421	2.506	NM_206955 NM_206956 NM_006115 NM_206953 NM_206954	PRAME	preferentially expressed antigen in melanoma
chr9_-_122679283	2.386		PHF19	PHD finger protein 19
chr9_-_122679387	2.333	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr16_-_69030421	2.308	NM_006927	ST3GAL2	ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr21_-_43368963	2.291	NM_000071	CBS	cystathionine-beta-synthase
chr8_+_144706699	2.269	NM_001166237	GSDMD	gasdermin D
chrX_-_152139267	2.243	NM_004988	MAGEA1	melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
chr20_-_55533544	2.152	NM_080618	CTCFL	CCCTC-binding factor (zinc finger protein)-like
chrX_+_151633730	2.146	NM_005361 NM_175742 NM_175743	MAGEA2	melanoma antigen family A, 2
chrX_-_151672985	2.112	NM_005361 NM_175742 NM_175743	MAGEA2	melanoma antigen family A, 2
chrX_-_151653756	1.981	NM_001166386 NM_001166387 NM_005367	MAGEA12	melanoma antigen family A, 12
chrX_-_39841599	1.962	NM_001123385 NM_017745	BCOR	BCL6 corepressor
chr7_-_100077072	1.957	NM_003227	TFR2	transferrin receptor 2
chr1_-_154318412	1.956	NM_001093725	MEX3A	mex-3 homolog A (C. elegans)
chr2_+_200031333	1.944
chr3_-_71715431	1.925	NM_001012505 NM_032682	FOXP1	forkhead box P1
chr15_+_74416156	1.925	NM_145805	ISL2	ISL LIM homeobox 2
chrX_+_151653874	1.887	NM_001102576 NM_153478	CSAG1	chondrosarcoma associated gene 1
chr20_-_62151216	1.884	NM_018419	SOX18	SRY (sex determining region Y)-box 18
chr15_+_74416129	1.855		ISL2	ISL LIM homeobox 2
chr7_-_100331417	1.849	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr21_-_43369492	1.839	NM_001178008 NM_001178009	CBS	cystathionine-beta-synthase
chr12_-_52980984	1.800	NM_001136023	NFE2	nuclear factor (erythroid-derived 2), 45kDa
chr12_-_52980914	1.772		NFE2	nuclear factor (erythroid-derived 2), 45kDa
chr19_+_3317589	1.753		NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr19_+_3317575	1.737		NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr12_+_54700955	1.731	NM_022465	IKZF4	IKAROS family zinc finger 4 (Eos)
chr22_+_19699441	1.721	NM_001159554 NM_005446	P2RX6	purinergic receptor P2X, ligand-gated ion channel, 6
chr17_+_77582774	1.711	NM_005052	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr17_-_44010543	1.702	NM_024015	HOXB4	homeobox B4
chr15_-_41589958	1.700	NM_005657	TP53BP1	tumor protein p53 binding protein 1
chr1_-_182273114	1.684		GLT25D2	glycosyltransferase 25 domain containing 2
chr12_+_56135353	1.672	NM_031479	INHBE	inhibin, beta E
chr1_+_20385164	1.655	NM_152376	UBXN10	UBX domain protein 10
chr6_+_14032655	1.647	NM_001165034	RNF182	ring finger protein 182
chr16_+_387176	1.577	NM_005009	NME4	non-metastatic cells 4, protein expressed in
chr17_+_75366524	1.565	NM_005189 NM_032647	CBX2	chromobox homolog 2
chr6_-_29703725	1.558		GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr9_+_129962292	1.539	NM_024112	C9orf16	chromosome 9 open reading frame 16
chr7_+_150390566	1.494		SLC4A2	solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr12_-_6586811	1.486	NM_001273	CHD4	chromodomain helicase DNA binding protein 4
chr4_-_109308893	1.481	NM_001130713 NM_001130714 NM_016269	LEF1	lymphoid enhancer-binding factor 1
chr1_-_38243716	1.446		FHL3	four and a half LIM domains 3
chr8_+_41804946	1.435
chr10_-_76538859	1.421	NM_001007271 NM_001007272 NM_001007273	DUSP13	dual specificity phosphatase 13
chr5_+_176446425	1.417	NM_002011 NM_213647	FGFR4	fibroblast growth factor receptor 4
chrX_-_153632355	1.407	NM_001081573 NM_080612	GAB3	GRB2-associated binding protein 3
chr17_-_77474597	1.384	NM_032711	MAFG	v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr14_-_21064182	1.358		SALL2	sal-like 2 (Drosophila)
chr1_-_38243747	1.353	NM_004468	FHL3	four and a half LIM domains 3
chr7_-_150411345	1.328	NM_031434	TMUB1	transmembrane and ubiquitin-like domain containing 1
chr15_-_20637731	1.324	NM_144599	NIPA1	non imprinted in Prader-Willi/Angelman syndrome 1
chr2_-_144991556	1.322		ZEB2	zinc finger E-box binding homeobox 2
chr2_-_220144511	1.320	NM_001173408 NM_001173431 NM_015311	OBSL1	obscurin-like 1
chr19_+_3317536	1.317	NM_005597	NFIC	nuclear factor I/C (CCAAT-binding transcription factor)
chr14_-_20563698	1.317		NDRG2	NDRG family member 2
chr1_-_1283770	1.309	NM_032348	MXRA8	matrix-remodelling associated 8
chr11_+_46359821	1.308		MDK	midkine (neurite growth-promoting factor 2)
chr5_+_76181581	1.305	NM_130772	S100Z	S100 calcium binding protein Z
chr6_+_32229599	1.276	NM_005155	PPT2-EGFL8 PPT2	PPT2-EGFL8 read-through transcript palmitoyl-protein thioesterase 2
chr12_+_6807831	1.270	NM_014262	LEPREL2	leprecan-like 2
chr11_+_46359855	1.269		MDK	midkine (neurite growth-promoting factor 2)
chr14_-_20563722	1.257	NM_016250 NM_201535 NM_201536 NM_201537	NDRG2	NDRG family member 2
chr19_+_17723285	1.248	NM_001161359 NM_015122	FCHO1	FCH domain only 1
chr7_-_92303865	1.242	NM_001145306	CDK6	cyclin-dependent kinase 6
chr10_+_21863099	1.241	NM_001195627 NM_001195628 NM_001195630 NM_004641	MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr19_-_51168396	1.240	NM_002516	NOVA2	neuro-oncological ventral antigen 2
chr14_+_104267270	1.238	NM_199165	ADSSL1	adenylosuccinate synthase like 1
chr12_+_56202874	1.226	NM_052897	MBD6	methyl-CpG binding domain protein 6
chr5_+_139008667	1.225		CXXC5	CXXC finger protein 5
chr11_+_46359836	1.225		MDK	midkine (neurite growth-promoting factor 2)
chr7_+_74017015	1.223	NM_001145063	GATSL1 GATSL2	GATS protein-like 1 GATS protein-like 2
chr7_-_92303812	1.216		CDK6	cyclin-dependent kinase 6
chr20_-_22513050	1.215	NM_021784	FOXA2	forkhead box A2
chr21_-_10120690	1.214	NM_001187 NM_182484 NM_181704 NM_182481 NM_182482	BAGE BAGE5 BAGE4 BAGE3 BAGE2	B melanoma antigen B melanoma antigen family, member 5 B melanoma antigen family, member 4 B melanoma antigen family, member 3 B melanoma antigen family, member 2
chr15_-_80125403	1.206	NM_032246	MEX3B	mex-3 homolog B (C. elegans)
chr2_-_200030944	1.205	NM_001172509	SATB2	SATB homeobox 2
chr15_+_89299060	1.199	NM_001017919 NM_033544	RCCD1	RCC1 domain containing 1
chr1_+_26896519	1.191		ARID1A	AT rich interactive domain 1A (SWI-like)
chr9_-_126945536	1.172	NM_001144877 NM_173690	SCAI	suppressor of cancer cell invasion
chr6_+_32229771	1.154		PPT2-EGFL8 PPT2	PPT2-EGFL8 read-through transcript palmitoyl-protein thioesterase 2
chr6_-_29703913	1.148	NM_021903	GABBR1	gamma-aminobutyric acid (GABA) B receptor, 1
chr3_+_20056527	1.136	NM_003884	KAT2B	K(lysine) acetyltransferase 2B
chr19_-_60350122	1.129		TNNT1	troponin T type 1 (skeletal, slow)
chr10_+_22650145	1.126		BMI1	BMI1 polycomb ring finger oncogene
chr1_-_149214063	1.120	NM_022075 NM_181746	LASS2	LAG1 homolog, ceramide synthase 2
chr1_-_47468029	1.104	NM_003189	TAL1	T-cell acute lymphocytic leukemia 1
chr19_+_4442610	1.096		HDGFRP2	hepatoma-derived growth factor-related protein 2
chr1_-_200397300	1.095		PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr17_+_1580504	1.094		WDR81	WD repeat domain 81
chr19_+_10261646	1.085	NM_003259	ICAM5	intercellular adhesion molecule 5, telencephalin
chr20_-_22512893	1.081		FOXA2	forkhead box A2
chr20_-_49592444	1.081		NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr19_+_522260	1.074	NM_198591	BSG	basigin (Ok blood group)
chr19_-_18409788	1.073	NM_001170939	ISYNA1	inositol-3-phosphate synthase 1
chrX_+_117513899	1.072	NM_144658	DOCK11	dedicator of cytokinesis 11
chr10_+_21863272	1.065		MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr1_+_945331	1.053	NM_198576	AGRN	agrin
chr1_+_153241858	1.052		ZBTB7B	zinc finger and BTB domain containing 7B
chr19_+_14405216	1.048		PKN1	protein kinase N1
chr11_+_279113	1.042	NM_025092	ATHL1	ATH1, acid trehalase-like 1 (yeast)
chr12_-_6586736	1.040		CHD4	chromodomain helicase DNA binding protein 4
chr21_+_46473494	1.034		MCM3AP-AS1	MCM3AP antisense RNA 1 (non-protein coding)
chr7_+_733182	1.032		HEATR2	HEAT repeat containing 2
chr1_-_27802688	1.031	NM_001029882	AHDC1	AT hook, DNA binding motif, containing 1
chr10_+_21863388	1.022		MLLT10	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr11_+_46359781	1.015	NM_002391	MDK	midkine (neurite growth-promoting factor 2)
chr8_-_125252884	1.014		C8orf78	chromosome 8 open reading frame 78
chr21_-_46428728	1.012		C21orf56	chromosome 21 open reading frame 56
chr17_-_39700960	1.006	NM_000342	SLC4A1	solute carrier family 4, anion exchanger, member 1 (erythrocyte membrane protein band 3, Diego blood group)
chr9_+_70509925	0.995	NM_003558	PIP5K1B	phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chrX_+_119176494	0.992	NM_001099685 NM_032498	RHOXF2B RHOXF2	Rhox homeobox family, member 2B Rhox homeobox family, member 2
chr3_-_178397706	0.992	NM_024665	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1
chr6_+_32230172	0.991		PPT2	palmitoyl-protein thioesterase 2
chr15_+_41597097	0.989	NM_002373	MAP1A	microtubule-associated protein 1A
chr11_+_46359878	0.988	NM_001012333	MDK	midkine (neurite growth-promoting factor 2)
chr21_-_46428768	0.988		C21orf56	chromosome 21 open reading frame 56
chr8_+_21833162	0.982		XPO7	exportin 7
chr3_+_171558188	0.982		SKIL	SKI-like oncogene
chr2_-_130603264	0.976	NM_001099771	POTEF	POTE ankyrin domain family, member F
chr16_+_2742606	0.961		SRRM2	serine/arginine repetitive matrix 2
chr19_-_16868674	0.960		CPAMD8	C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr7_+_149733309	0.957
chr5_-_88215034	0.956	NM_001193350 NM_002397	MEF2C	myocyte enhancer factor 2C
chr16_+_29725311	0.953	NM_001042539 NM_002383	MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr5_-_176833197	0.950		DBN1	drebrin 1
chr8_+_21833111	0.942	NM_015024	XPO7	exportin 7
chr7_+_64136078	0.941		CCT6P3	chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr1_+_945399	0.938
chr16_-_28515868	0.938	NM_001054	SULT1A2	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr19_+_811615	0.937		CFD	complement factor D (adipsin)
chr19_-_15421761	0.930	NM_021241	WIZ	widely interspaced zinc finger motifs
chr19_-_4017739	0.929	NM_015898	ZBTB7A	zinc finger and BTB domain containing 7A
chr3_-_159306214	0.929
chr19_-_8581559	0.924	NM_030957	ADAMTS10	ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr19_-_7896974	0.924	NM_206833	CTXN1	cortexin 1
chr8_-_145881968	0.919		ARHGAP39	Rho GTPase activating protein 39
chr6_+_7052798	0.911	NM_001168344	RREB1	ras responsive element binding protein 1
chr21_-_46428788	0.909	NM_001142854 NM_032261	C21orf56	chromosome 21 open reading frame 56
chr14_-_90352513	0.909	NM_001010854	TTC7B	tetratricopeptide repeat domain 7B
chr11_+_64694200	0.907	NM_001008778	SPDYC	speedy homolog C (Xenopus laevis)
chr14_-_20562962	0.906	NM_201538 NM_201539 NM_201540 NM_201541	NDRG2	NDRG family member 2
chr7_-_20793028	0.905	NM_182700 NM_198956	SP8	Sp8 transcription factor
chr17_-_71352090	0.903		UNC13D	unc-13 homolog D (C. elegans)
chr19_+_61344341	0.901	NM_018337	ZNF444	zinc finger protein 444
chr19_-_18409971	0.900	NM_001170938 NM_016368	ISYNA1	inositol-3-phosphate synthase 1
chr7_+_101245812	0.898	NM_001913 NM_181500	CUX1	cut-like homeobox 1
chr16_+_56286212	0.894	NM_032269	CCDC135	coiled-coil domain containing 135
chrX_-_148476903	0.893	NM_005365 NM_001080790	MAGEA9 MAGEA9B	melanoma antigen family A, 9 melanoma antigen family A, 9B
chr16_+_84202515	0.890	NM_001134473	KIAA0182	KIAA0182
chr2_-_171725150	0.887		TLK1	tousled-like kinase 1
chrX_-_119095544	0.884	NM_001099685 NM_032498	RHOXF2B RHOXF2	Rhox homeobox family, member 2B Rhox homeobox family, member 2
chr10_-_75085754	0.881	NM_001114133	SYNPO2L	synaptopodin 2-like
chr3_+_171558215	0.879		SKIL	SKI-like oncogene
chr2_+_42649105	0.877	NM_020744	MTA3	metastasis associated 1 family, member 3
chr1_-_149213916	0.875		LASS2	LAG1 homolog, ceramide synthase 2
chr10_+_22649977	0.872	NM_005180	BMI1	BMI1 polycomb ring finger oncogene
chr19_+_61344501	0.871		ZNF444	zinc finger protein 444
chr6_-_68655708	0.871
chr11_-_133786935	0.860	NM_018644 NM_054025	B3GAT1	beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chrX_-_153632990	0.853		GAB3	GRB2-associated binding protein 3
chr1_-_149213826	0.853		LASS2	LAG1 homolog, ceramide synthase 2
chr3_+_20056857	0.852		KAT2B	K(lysine) acetyltransferase 2B
chr12_+_54832470	0.849	NM_002475	MYL6B	myosin, light chain 6B, alkali, smooth muscle and non-muscle
chr7_+_154426064	0.848		LOC202781	hypothetical LOC202781
chrX_+_128501862	0.843	NM_000276 NM_001587	OCRL	oculocerebrorenal syndrome of Lowe
chr8_-_145671947	0.842		FOXH1	forkhead box H1
chr7_-_150305933	0.842	NM_000238 NM_172056	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr19_-_60350118	0.839		TNNT1	troponin T type 1 (skeletal, slow)
chr3_-_178397621	0.839		TBL1XR1	transducin (beta)-like 1 X-linked receptor 1
chr19_-_18515280	0.839		FKBP8	FK506 binding protein 8, 38kDa
chr7_-_733401	0.837	NM_001164760	PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta
chr1_-_149213929	0.837		LASS2	LAG1 homolog, ceramide synthase 2
chr6_+_14033076	0.834	NM_001165032 NM_152737	RNF182	ring finger protein 182
chr2_+_46779553	0.830	NM_014011	SOCS5	suppressor of cytokine signaling 5
chr2_+_42649348	0.829		MTA3	metastasis associated 1 family, member 3
chr7_-_733812	0.823	NM_001164758 NM_001164759	PRKAR1B	protein kinase, cAMP-dependent, regulatory, type I, beta
chr4_+_191226073	0.823	NM_012147 NM_001177376 NM_001127388 NM_001127389 NM_001164467	DUX2 DUX4L4 DUX4L6 DUX4L5 DUX4L3	double homeobox 2 double homeobox 4 like 4 double homeobox 4 like 6 double homeobox 4 like 5 double homeobox 4 like 3
chr19_-_18515376	0.817	NM_012181	FKBP8	FK506 binding protein 8, 38kDa
chr3_+_171558143	0.817	NM_001145098 NM_005414	SKIL	SKI-like oncogene
chr19_-_5291700	0.815	NM_002850 NM_130853 NM_130854 NM_130855	PTPRS	protein tyrosine phosphatase, receptor type, S
chr3_-_185578621	0.808	NM_000460 NM_001177597 NM_001177598	THPO	thrombopoietin
chr1_+_153241665	0.801	NM_015872	ZBTB7B	zinc finger and BTB domain containing 7B
chr16_+_84204424	0.799	NM_014615	KIAA0182	KIAA0182
chr1_-_23977330	0.798		LOC100506963	hypothetical LOC100506963
chr11_+_34029764	0.798	NM_005898 NM_203364	CAPRIN1	cell cycle associated protein 1
chr1_-_149213778	0.798		LASS2	LAG1 homolog, ceramide synthase 2
chr14_-_90352395	0.797
chr7_-_74705276	0.797	NM_001145064	GATSL2	GATS protein-like 2
chr10_-_7491204	0.790	NM_001018039	SFMBT2	Scm-like with four mbt domains 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.55	1.21e-12	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.93	1.80e-12	GO:0016568	chromatin modification
1.42	1.32e-11	GO:0007399	nervous system development
1.31	3.78e-10	GO:0051252	regulation of RNA metabolic process
1.71	4.54e-10	GO:0007417	central nervous system development
1.13	4.70e-10	GO:0065007	biological regulation
1.28	1.34e-09	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.27	2.52e-09	GO:0051171	regulation of nitrogen compound metabolic process
1.28	3.98e-09	GO:0010468	regulation of gene expression
1.22	9.36e-09	GO:0031323	regulation of cellular metabolic process
1.51	1.01e-08	GO:0048699	generation of neurons
1.20	2.63e-08	GO:0019222	regulation of metabolic process
1.48	2.87e-08	GO:0022008	neurogenesis
1.22	3.68e-08	GO:0080090	regulation of primary metabolic process
1.13	4.64e-08	GO:0050789	regulation of biological process
1.28	1.14e-07	GO:0006355	regulation of transcription, DNA-dependent
1.22	1.31e-07	GO:0007275	multicellular organismal development
1.65	1.99e-07	GO:0006325	chromatin organization
1.25	2.14e-07	GO:0031326	regulation of cellular biosynthetic process
1.24	2.15e-07	GO:0048731	system development
1.24	3.14e-07	GO:0009889	regulation of biosynthetic process
1.52	3.36e-07	GO:0030182	neuron differentiation
1.22	3.63e-07	GO:0048856	anatomical structure development
1.53	4.28e-07	GO:0010628	positive regulation of gene expression
1.73	4.88e-07	GO:0007420	brain development
1.53	5.68e-07	GO:0051254	positive regulation of RNA metabolic process
1.21	6.20e-07	GO:0060255	regulation of macromolecule metabolic process
1.19	8.21e-07	GO:0032502	developmental process
1.12	9.35e-07	GO:0050794	regulation of cellular process
1.25	9.98e-07	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.23	4.27e-06	GO:0048518	positive regulation of biological process
1.52	4.71e-06	GO:0045893	positive regulation of transcription, DNA-dependent
1.46	7.09e-06	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.24	7.88e-06	GO:0010556	regulation of macromolecule biosynthetic process
1.44	1.35e-05	GO:0051173	positive regulation of nitrogen compound metabolic process
1.23	1.49e-05	GO:0048522	positive regulation of cellular process
1.46	2.78e-05	GO:0009790	embryo development
1.46	4.19e-05	GO:0045595	regulation of cell differentiation
1.48	4.72e-05	GO:0051276	chromosome organization
1.54	6.31e-05	GO:0019226	transmission of nerve impulse
1.54	6.31e-05	GO:0035637	multicellular organismal signaling
1.26	9.40e-05	GO:0048513	organ development
1.89	9.88e-05	GO:0016569	covalent chromatin modification
1.32	9.89e-05	GO:0009893	positive regulation of metabolic process
1.24	1.20e-04	GO:0048523	negative regulation of cellular process
1.33	1.37e-04	GO:0010604	positive regulation of macromolecule metabolic process
1.56	1.46e-04	GO:0007268	synaptic transmission
1.33	1.57e-04	GO:0031325	positive regulation of cellular metabolic process
1.59	1.60e-04	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.50	1.77e-04	GO:0051253	negative regulation of RNA metabolic process
1.37	1.77e-04	GO:0048468	cell development
1.53	2.33e-04	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.86	2.78e-04	GO:0016570	histone modification
1.24	2.92e-04	GO:0030154	cell differentiation
1.22	3.45e-04	GO:0048519	negative regulation of biological process
1.49	4.07e-04	GO:0045892	negative regulation of transcription, DNA-dependent
1.06	4.68e-04	GO:0009987	cellular process
1.23	5.09e-04	GO:0048869	cellular developmental process
1.58	5.68e-04	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.53	5.89e-04	GO:0032583	regulation of gene-specific transcription
1.44	6.14e-04	GO:0051172	negative regulation of nitrogen compound metabolic process
2.76	6.42e-04	GO:0048663	neuron fate commitment
1.85	6.77e-04	GO:0030900	forebrain development
1.44	7.04e-04	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.37	8.76e-04	GO:0009891	positive regulation of biosynthetic process
1.62	8.98e-04	GO:0060284	regulation of cell development
1.41	9.00e-04	GO:0009890	negative regulation of biosynthetic process
1.27	9.41e-04	GO:0009653	anatomical structure morphogenesis
1.39	1.12e-03	GO:0010557	positive regulation of macromolecule biosynthetic process
1.37	1.29e-03	GO:0031328	positive regulation of cellular biosynthetic process
1.41	1.34e-03	GO:0031327	negative regulation of cellular biosynthetic process
1.38	1.51e-03	GO:0007267	cell-cell signaling
1.33	1.56e-03	GO:0007154	cell communication
1.16	1.82e-03	GO:0016043	cellular component organization
1.43	2.25e-03	GO:0010629	negative regulation of gene expression
1.34	2.67e-03	GO:0031324	negative regulation of cellular metabolic process
1.47	2.76e-03	GO:0000904	cell morphogenesis involved in differentiation
2.21	3.56e-03	GO:0021953	central nervous system neuron differentiation
1.27	6.44e-03	GO:0051239	regulation of multicellular organismal process
1.31	6.59e-03	GO:0009892	negative regulation of metabolic process
1.65	7.14e-03	GO:0050767	regulation of neurogenesis
1.40	7.35e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.41	7.76e-03	GO:0009887	organ morphogenesis
1.32	8.57e-03	GO:0050793	regulation of developmental process
1.15	9.21e-03	GO:0071840	cellular component organization or biogenesis
1.59	1.14e-02	GO:0051960	regulation of nervous system development
1.81	1.40e-02	GO:0045165	cell fate commitment
1.60	1.41e-02	GO:0045596	negative regulation of cell differentiation
2.27	1.50e-02	GO:0007519	skeletal muscle tissue development
1.40	1.50e-02	GO:0048666	neuron development
1.46	1.81e-02	GO:0048667	cell morphogenesis involved in neuron differentiation
1.37	2.13e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
2.21	2.13e-02	GO:0060538	skeletal muscle organ development
1.49	2.27e-02	GO:0048598	embryonic morphogenesis
1.17	2.94e-02	GO:0071842	cellular component organization at cellular level
1.66	3.66e-02	GO:0045664	regulation of neuron differentiation
1.45	4.02e-02	GO:0007409	axonogenesis
1.31	4.35e-02	GO:0051128	regulation of cellular component organization
1.30	4.86e-02	GO:0006351	transcription, DNA-dependent

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.28	9.75e-07	GO:0031981	nuclear lumen
1.24	1.20e-06	GO:0043233	organelle lumen
1.07	1.71e-06	GO:0044424	intracellular part
1.14	1.71e-06	GO:0005634	nucleus
1.24	2.71e-06	GO:0070013	intracellular organelle lumen
1.23	3.10e-06	GO:0031974	membrane-enclosed lumen
1.24	6.68e-06	GO:0044428	nuclear part
1.06	7.28e-06	GO:0005622	intracellular
1.43	1.05e-05	GO:0044451	nucleoplasm part
1.18	6.11e-05	GO:0043234	protein complex
1.07	2.18e-04	GO:0043226	organelle
1.07	2.51e-04	GO:0043229	intracellular organelle
1.28	2.72e-04	GO:0005654	nucleoplasm
1.07	7.40e-04	GO:0043227	membrane-bounded organelle
1.07	7.60e-04	GO:0043231	intracellular membrane-bounded organelle
1.14	1.99e-03	GO:0032991	macromolecular complex
3.51	2.15e-03	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.56	8.46e-03	GO:0005667	transcription factor complex
1.09	3.61e-02	GO:0044422	organelle part
3.07	4.08e-02	GO:0031519	PcG protein complex
3.64	4.79e-02	GO:0042627	chylomicron

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.72	7.89e-16	GO:0043565	sequence-specific DNA binding
1.57	2.55e-15	GO:0030528	transcription regulator activity
1.15	1.14e-12	GO:0005515	protein binding
1.44	1.55e-08	GO:0001071	nucleic acid binding transcription factor activity
1.44	1.55e-08	GO:0003700	sequence-specific DNA binding transcription factor activity
1.95	2.07e-07	GO:0000975	regulatory region DNA binding
1.95	2.07e-07	GO:0001067	regulatory region nucleic acid binding
1.95	2.07e-07	GO:0044212	transcription regulatory region DNA binding
1.95	3.86e-07	GO:0010843	promoter binding
1.72	8.54e-07	GO:0016563	transcription activator activity
1.06	4.17e-05	GO:0005488	binding
1.21	8.65e-05	GO:0003677	DNA binding
1.16	4.55e-04	GO:0003676	nucleic acid binding
1.57	1.31e-03	GO:0016564	transcription repressor activity
1.71	2.50e-03	GO:0003682	chromatin binding
1.45	4.76e-03	GO:0019904	protein domain specific binding
4.04	6.83e-03	GO:0042974	retinoic acid receptor binding
1.74	1.97e-02	GO:0022843	voltage-gated cation channel activity
1.43	2.31e-02	GO:0022838	substrate-specific channel activity
1.43	3.01e-02	GO:0005216	ion channel activity
1.51	4.40e-02	GO:0005261	cation channel activity
1.61	4.58e-02	GO:0005244	voltage-gated ion channel activity
1.61	4.58e-02	GO:0022832	voltage-gated channel activity