Motif ID: ADNP_IRX_SIX_ZHX.p2

Z-value: 0.877


Transcription factors associated with ADNP_IRX_SIX_ZHX.p2:

Gene SymbolEntrez IDGene Name
ADNP 23394 activity-dependent neuroprotector homeobox
IRX4 50805 iroquois homeobox 4
IRX5 10265 iroquois homeobox 5
SIX2 10736 SIX homeobox 2
SIX5 147912 SIX homeobox 5
ZHX1 11244 zinc fingers and homeoboxes 1
ZHX2 22882 zinc fingers and homeoboxes 2
ZHX3 23051 zinc fingers and homeoboxes 3

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZHX3chr20_-_393621220.702.7e-03Click!
SIX2chr2_-_450900250.381.5e-01Click!
ZHX2chr8_+_123863075-0.381.5e-01Click!
IRX5chr16_+_535226110.351.9e-01Click!
SIX5chr19_-_50964336-0.243.7e-01Click!
IRX4chr5_-_1935764-0.175.3e-01Click!
ZHX1chr8_-_124355670-0.165.6e-01Click!
ADNPchr20_-_48980858-0.087.6e-01Click!


Activity profile for motif ADNP_IRX_SIX_ZHX.p2.

activity profile for motif ADNP_IRX_SIX_ZHX.p2


Sorted Z-values histogram for motif ADNP_IRX_SIX_ZHX.p2

Sorted Z-values for motif ADNP_IRX_SIX_ZHX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ADNP_IRX_SIX_ZHX.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_55489973 2.282 WNT5A
wingless-type MMTV integration site family, member 5A
chr3_-_115960807 1.558 NM_001164344
NM_001164345
 ZBTB20

zinc finger and BTB domain containing 20

chr16_+_7322751 1.405 NM_145891
NM_145892
NM_145893
 RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr12_+_52697160 1.397 HOXC5
HOXC6
homeobox C5
homeobox C6
chr11_+_10433241 1.276 NM_001025389
 AMPD3
adenosine monophosphate deaminase 3
chr3_-_143230124 1.255 NM_001178141
NM_001178142
NM_006286
 TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr9_+_102380156 1.224 NM_001018116
 MURC
muscle-related coiled-coil protein
chr5_+_125786975 1.169 GRAMD3
GRAM domain containing 3
chr8_+_77756061 1.153 NM_024721
 ZFHX4
zinc finger homeobox 4
chr12_+_52696908 1.139 NM_014620
NM_153693
 HOXC4
HOXC6
homeobox C4
homeobox C6
chr2_-_190635566 1.132 NM_005259
 MSTN
myostatin
chr15_+_47502666 1.115 NM_002009
 FGF7
fibroblast growth factor 7
chr13_+_100902942 1.092 NM_004791
 ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr15_-_53996597 1.086 NM_198400
 NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr8_+_77756077 1.081 ZFHX4
zinc finger homeobox 4
chr11_-_85107569 1.063 NM_206929
 SYTL2
synaptotagmin-like 2
chr5_+_155686333 1.029 NM_000337
NM_001128209
NM_172244
 SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr8_-_72431274 1.009 NM_172058
NM_172059
NM_172060
 EYA1


eyes absent homolog 1 (Drosophila)


chr17_-_10265991 1.009 NM_002472
 MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr1_-_191422346 0.979 NM_003783
 B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
2.71 1.39e-16 GO:0007606 sensory perception of chemical stimulus
2.71 1.07e-14 GO:0007608 sensory perception of smell
2.19 4.37e-02 GO:0007517 muscle organ development
2.01 5.98e-11 GO:0007600 sensory perception
1.61 8.70e-07 GO:0050877 neurological system process
1.61 1.26e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
1.54 5.80e-07 GO:0003008 system process
1.24 2.60e-05 GO:0032501 multicellular organismal process
1.17 7.46e-03 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
enrichment   p-value GO term description
1.26 3.10e-05 GO:0071944 cell periphery
1.25 8.66e-05 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
2.81 3.48e-16 GO:0004984 olfactory receptor activity
2.00 7.11e-12 GO:0004930 G-protein coupled receptor activity
1.70 2.35e-09 GO:0004888 transmembrane receptor activity
1.52 5.87e-07 GO:0004872 receptor activity
1.40 3.31e-05 GO:0004871 signal transducer activity
1.40 3.31e-05 GO:0060089 molecular transducer activity