Mean activities

Top 10 and bottom 10 mean activities.

 Mean activities

Mean activities sorted by motif Z-value.

 Mean activities

Sorted mean activities for every motif.
Motif nameMean activityZ-ValueAssociated genesLogo
STAT5{A,B}.p2 0.352 1.085 STAT5B
STAT5A (MGF)
XBP1.p3 0.317 1.077 XBP1
RXRG_dimer.p3 0.297 0.820 NR1H2 (NER, NER-I, RIP15, LXR-b)
RXRA (NR2B1)
PPARG (PPARG1, PPARG2, NR1C3, PPARgamma)
PPARA (hPPAR, NR1C1)
RXRB (NR2B2, H-2RIIBP, RCoR-1)
RXRG (NR2B3)
PRDM1.p3 0.296 0.812 PRDM1 (PRDI-BF1)
CREB1.p2 0.292 2.097 CREB1
ZNF143.p2 0.264 3.551 ZNF143 (SBF, pHZ-1, STAF)
ELK1,4_GABP{A,B1}.p3 0.247 3.704 GABPA (E4TF1A, NFT2, NRF2, E4TF1-60, NRF2A)
GABPB1 (E4TF1-47, GABPB)
ELK4 (SAP1)
ELK1
IRF1,2,7.p3 0.238 1.296 IRF1 (MAR, IRF-1)
IRF2 (IRF-2, DKFZp686F0244)
IRF7 (IRF7A, IRF-7H)
NRF1.p2 0.233 4.527 NRF1 (EWG, ALPHA-PAL)
EHF.p2 0.223 2.569 EHF
FOX{D1,D2}.p2 0.219 1.140 FOXD2 (FREAC9)
FOXD1 (FREAC4)
CTCF.p2 0.209 1.232 CTCF
E2F1..5.p2 0.203 1.544 E2F4 (E2F-4)
E2F5
E2F2 (E2F-2)
E2F1 (RBP3)
E2F3
NFIL3.p2 0.184 0.489 NFIL3 (E4BP4, NFIL3A, NF-IL3A)
ATF5_CREB3.p2 0.174 1.616 ATF5
CREB3 (LZIP, Luman)
FOS_FOS{B,L1}_JUN{B,D}.p2 0.172 0.955 FOS (c-fos, AP-1)
JUNB
FOSL1 (fra-1)
JUND (AP-1)
FOSB (G0S3, GOSB, GOS3, AP-1, MGC42291, DKFZp686C0818)
FOXN1.p2 0.164 0.961 FOXN1 (FKHL20)
NFY{A,B,C}.p2 0.149 1.981 NFYC (CBF-C)
NFYB (CBF-A, HAP3)
NFYA (HAP2, CBF-B)
PAX2.p2 0.139 1.429 PAX2
ATF4.p2 0.138 0.910 ATF4 (TAXREB67, CREB-2)
SREBF1,2.p2 0.137 0.721 SREBF1 (SREBP1, bHLHd1)
SREBF2 (SREBP2, bHLHd2)
YY1.p2 0.122 3.050 YY1 (NF-E1, DELTA, UCRBP, YIN-YANG-1, INO80S)
GFI1.p2 0.112 1.116 GFI1
HBP1_HMGB_SSRP1_UBTF.p2 0.109 0.868 HMGB2
HMGB3 (HMG2A, MGC90319)
SSRP1 (FACT80)
UBTF (UBF, NOR-90)
HBP1
ELF1,2,4.p2 0.107 1.951 ELF2 (EU32, NERF, NERF-2, NERF-1A, NERF-1B)
ELF1
ELF4 (MEF, ELFR)
SOX{8,9,10}.p2 0.103 0.715 SOX9 (SRA1)
SOX8
SOX10 (DOM, WS4, WS2E)
MYB.p2 0.097 0.941 MYB (c-myb)
NFKB1_REL_RELA.p2 0.085 0.720 RELA (p65)
REL (I-Rel)
NFKB1 (KBF1, p105)
PBX1.p2 0.079 0.298 PBX1
HES1.p2 0.066 0.888 HES1 (FLJ20408, HES-1, Hes1, bHLHb39)
ESRRA.p2 0.058 0.302 ESRRA (ERR1, ERRalpha, NR3B1, ERRa)
bHLH_family.p2 0.058 0.696 ARNTL (MOP3, JAP3, BMAL1, PASD3, bHLHe5)
MITF (WS2A, MI, bHLHe32)
MXI1 (MXD2, MAD2, MXI, bHLHc11)
TFE3 (TFEA, bHLHe33)
CLOCK (KIAA0334, KAT13D, bHLHe8)
OLIG2 (RACK17, OLIGO2, bHLHe19)
MXD4 (MAD4, MSTP149, MST149, bHLHc12)
HEY2 (bHLHb32)
HEY1 (HESR-1, CHF2, HESR1, HRT-1, CHF-2, HERP2, BHLHb31)
HEYL (bHLHb33)
MLXIPL (WS-bHLH, MIO, CHREBP, MONDOB)
HES6 (bHLHc23)
MXD3 (MAD3, bHLHc13)
ARNTL2 (BMAL2, MOP9, CLIF, PASD9, bHLHe6)
ID1 (dJ857M17.1.2, bHLHb24)
MNT (ROX, MXD6, MAD6, bHLHd3)
OLIG1 (BHLHB6, bHLHe21)
NPAS2 (MOP4, PASD4, bHLHe9)
TLX2.p2 0.057 0.435 TLX2 (Enx, Tlx2, NCX)
TEAD1.p2 0.051 0.231 TEAD1 (TEF-1)
TEAD2 (ETF, TEF4, TEF-4, TEAD-2)
TEAD3 (TEF5, TEAD5, TEF-5, DTEF-1, ETFR-1, TEAD-3)
TEAD4 (TEF3, RTEF1, TEF-3, EFTR-2, TEFR-1, TCF13L1, hRTEF-1B)
RBPJ.p2 0.050 0.276 RBPJ (SUH, IGKJRB, RBPJK, KBF2, RBP-J, CBF1)
MAFB.p2 0.050 0.975 MAFB
NFIX.p2 0.048 0.225 NFIX (NF1A)
SP1.p2 0.045 1.926 SP1
NKX3-2.p2 0.045 0.441 NKX3-2 (NKX3B, NKX3.2)
POU2F1..3.p2 0.045 0.192 POU2F2 (OCT2)
POU2F1 (OCT1)
POU2F3 (OCT11, PLA-1, Skn-1a, Epoc-1)
BPTF.p2 0.041 0.799 BPTF (FAC1, NURF301)
NFE2L2.p2 0.040 0.142 NFE2L2 (NRF2)
AHR_ARNT_ARNT2.p2 0.036 0.571 ARNT (HIF-1beta, bHLHe2)
AHR
ARNT2 (KIAA0307, bHLHe1)
FOXD3.p2 0.036 0.418 FOXD3 (Genesis, HFH2)
IKZF1.p2 0.034 0.222 IKZF1 (hIk-1, LyF-1, Hs.54452, IKAROS)
HIF1A.p2 0.030 0.286 HIF1A (MOP1, HIF-1alpha, PASD8, HIF1)
EP300.p2 0.028 0.348 EP300 (p300, KAT3B)
TFDP1.p2 0.028 1.268 TFDP1 (Dp-1, DRTF1, DP1)
PAX5.p2 0.027 0.834 PAX5 (BSAP)
KLF4.p3 0.025 0.926 KLF4 (EZF, GKLF)
ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2 0.025 0.172 ARNT (HIF-1beta, bHLHe2)
MAX (bHLHd4)
MYC (c-Myc, bHLHe39)
USF1 (UEF, MLTFI, bHLHb11)
BHLHB2 (DEC1, bHLHe40)
ARNT2 (KIAA0307, bHLHe1)
SPI1.p2 0.024 0.551 SPI1 (PU.1, SPI-A, OF, SFPI1, SPI-1)
RFX1..5_RFXANK_RFXAP.p2 0.024 0.186 RFX1 (EF-C)
RFXAP
RFX5
RFXANK (BLS, RFX-B, ANKRA1, F14150_1, MGC138628)
RFX4
RFX3
RFX2 (FLJ14226)
EWSR1-FLI1.p2 0.024 0.090 FLI1 (EWSR2, SIC-1)
EWSR1 (EWS, K984G1.4)
HLF.p2 0.023 0.077 HLF (MGC33822)
FOXO1,3,4.p2 0.022 0.134 FOXO1 (FKH1)
FOXO4 (AFX1)
FOXO3 (AF6q21, FOXO2)
SPIB.p2 0.020 0.364 SPIB (SPI-B)
BACH2.p2 0.015 0.053 BACH2
PRRX1,2.p2 0.013 0.222 PRRX2 (PRX2, PMX2)
PRRX1 (PHOX1)
TFAP2{A,C}.p2 0.012 0.636 TFAP2C (AP2-GAMMA, ERF1, TFAP2G, hAP-2g)
TFAP2A (AP-2)
NHLH1,2.p2 0.011 0.213 NHLH1 (NSCL, NSCL1, bHLHa35)
NHLH2 (NSCL2, bHLHa34)
ZNF384.p2 0.010 0.098 ZNF384 (CAGH1A, CIZ, NMP4, NP)
ZBTB6.p2 0.009 0.107 ZBTB6 (ZID)
ESR1.p2 0.009 0.068 ESR1 (NR3A1, Era)
TP53.p2 0.006 0.026 TP53 (p53, LFS1)
STAT2,4,6.p2 0.006 0.066 STAT2 (STAT113)
STAT4
STAT6 (D12S1644, IL-4-STAT)
TFAP4.p2 0.004 0.039 TFAP4 (AP-4)
SOX17.p2 0.004 0.031 SOX17
TFAP2B.p2 0.003 0.098 TFAP2B (AP2-B)
SPZ1.p2 0.002 0.030 SPZ1 (NYD-TSP1, FLJ25709)
FOX{I1,J2}.p2 -0.001 -0.013 FOXI1 (FREAC6)
FOXJ2 (FHX)
NKX2-2,8.p2 -0.004 -0.019 NKX2-2 (NKX2.2)
NKX2-8 (NKX2.8, Nkx2-9)
MYBL2.p2 -0.005 -0.017 MYBL2 (BMYB, B-MYB)
NKX6-1,2.p2 -0.006 -0.026 NKX6-1 (Nkx6.1)
NKX6-2 (NKX6B, GTX, NKX6.1)
PATZ1.p2 -0.009 -0.323 PATZ1 (MAZR, dJ400N23, ZBTB19, ZSG, RIAZ, PATZ)
SRY.p2 -0.010 -0.082 SRY (TDF)
MZF1.p2 -0.011 -0.385 MZF1 (MZF1B, ZSCAN6, MZF-1, Zfp98)
NFE2.p2 -0.012 -0.046 NFE2 (NF-E2)
GTF2I.p2 -0.014 -0.424 GTF2I (TFII-I, BAP-135, SPIN, BTKAP1, DIWS, IB291)
ZIC1..3.p2 -0.014 -0.114 ZIC1 (ZIC, ZNF201)
ZIC2 (HPE5)
ZIC3 (HTX, ZNF203)
HOX{A6,A7,B6,B7}.p2 -0.015 -0.346 HOXB6
HOXA7
HOXB7
HOXA6
ATF6.p2 -0.015 -0.109 ATF6 (ATF6A)
EGR1..3.p2 -0.016 -0.359 EGR3 (PILOT)
EGR1 (TIS8, G0S30, NGFI-A, KROX-24, ZIF-268, AT225, ZNF225)
EGR2
ZFP161.p2 -0.020 -0.437 ZFP161 (ZNF478, ZBTB14)
HMX1.p2 -0.021 -0.155 HMX1 (H6, NKX5-3)
RXR{A,B,G}.p2 -0.022 -0.234 RXRA (NR2B1)
RXRB (NR2B2, H-2RIIBP, RCoR-1)
RXRG (NR2B3)
MEF2{A,B,C,D}.p2 -0.022 -0.145 MEF2A (RSRFC4, RSRFC9)
MEF2C
MEF2D
MEF2BNB-MEF2B (MEF2B, LOC729991-MEF2B)
MEF2B (RSRFR2, FLJ32648)
CUX2.p2 -0.024 -0.036 CUX2 (KIAA0293, CDP2)
STAT1,3.p3 -0.024 -0.054 STAT1 (STAT91, ISGF-3)
STAT3 (APRF)
JUN.p2 -0.025 -0.211 JUN (c-Jun, AP-1)
JUND (AP-1)
JUNB
IKZF2.p2 -0.025 -0.228 IKZF2 (Helios)
CDX1,2,4.p2 -0.026 -0.228 CDX1
CDX2
CDX4
DMAP1_NCOR{1,2}_SMARC.p2 -0.027 -0.127 SMARCA1 (SNF2LB, NURF140, ISWI, SWI)
SMARCC2 (BAF170, Rsc8, CRACC2)
SMARCA5 (hSNF2H, hISWI, ISWI)
NCOR1 (N-CoR, hCIT529I10, TRAC1, hN-CoR, KIAA1047, MGC104216)
NCOR2 (SMRT, SMRTE, TRAC-1, CTG26, TNRC14)
DMAP1 (DNMAP1, FLJ11543, KIAA1425, DNMTAP1, EAF2, SWC4)
MAZ.p2 -0.027 -1.056 MAZ (ZF87, Pur-1, Zif87, ZNF801)
ZNF148.p2 -0.028 -0.492 ZNF148 (BERF-1, ZBP-89, BFCOL1, HT-BETA, ZFP148, pHZ-52)
TCF4_dimer.p2 -0.031 -0.532 TCF4 (E2-2, ITF2, PTHS, SEF2, SEF2-1, SEF2-1A, SEF2-1B, bHLHb19, MGC149723, MGC149724)
FEV.p2 -0.031 -0.471 FEV (PET-1, HSRNAFEV)
ZEB1.p2 -0.040 -0.514 ZEB1 (BZP, ZEB, AREB6, NIL-2-A, Zfhep, Zfhx1a)
LEF1_TCF7_TCF7L1,2.p2 -0.040 -0.219 TCF7 (TCF-1)
TCF7L2 (TCF-4)
LEF1 (TCF1ALPHA)
TCF7L1
MTF1.p2 -0.040 -0.817 MTF1
NKX2-3_NKX2-5.p2 -0.041 -0.195 NKX2-5 (CSX1, NKX2.5, NKX4-1)
NKX2-3 (NKX2.3, CSX3, NKX4-3)
HIC1.p2 -0.042 -1.188 HIC1 (ZBTB29)
NFATC1..3.p2 -0.043 -0.369 NFATC3 (NFAT4, NFATX)
NFATC2 (NF-ATP, NFATp, NFAT1)
NFATC1 (NF-ATC, NFATc, NFAT2)
ADNP_IRX_SIX_ZHX.p2 -0.047 -0.350 SIX5
ZHX1
IRX4
ADNP (KIAA0784, ADNP1)
ZHX3 (KIAA0395)
ZHX2 (KIAA0854)
IRX5 (IRX-2a)
SIX2
NANOG.p2 -0.047 -0.156 NANOG (FLJ12581, FLJ40451)
ZBTB16.p2 -0.048 -0.375 ZBTB16 (PLZF)
PAX4.p2 -0.054 -0.236 PAX4
FOXQ1.p2 -0.054 -0.288 FOXQ1 (HFH1)
SOX2.p2 -0.055 -0.445 SOX2
PDX1.p2 -0.064 -0.082 PDX1 (IDX-1, STF-1, PDX-1, MODY4)
TFEB.p2 -0.065 -0.480 TFEB
EBF1.p2 -0.065 -0.620 EBF1 (OLF1)
SRF.p3 -0.066 -0.186 SRF (MCM1)
LMO2.p2 -0.066 -0.748 LMO2 (TTG2, RHOM2, RBTN2)
CRX.p2 -0.068 -0.376 CRX (CRD, LCA7, OTX3)
TBX4,5.p2 -0.070 -0.513 TBX5
TBX4
GLI1..3.p2 -0.072 -0.543 GLI1
GLI2 (THP2, HPE9, THP1)
GLI3 (PAP-A, PAPA, PAPA1, PAPB, ACLS, PPDIV)
POU5F1.p2 -0.075 -0.610 POU5F1 (OCT3, Oct4, MGC22487)
ATF2.p2 -0.076 -0.440 ATF2 (TREB7, CRE-BP1, HB16)
HMGA1,2.p2 -0.083 -0.869 HMGA1
HMGA2 (BABL, LIPO)
GZF1.p2 -0.083 -0.072 GZF1 (dJ322G13.2, ZBTB23)
FOX{F1,F2,J1}.p2 -0.084 -0.333 FOXF2 (FREAC2)
FOXJ1 (HFH-4, HFH4)
FOXF1 (FREAC1)
TFCP2.p2 -0.084 -1.304 TFCP2 (CP2, LSF, LBP-1C, TFCP2C)
MYFfamily.p2 -0.086 -1.818 MYOD1 (PUM, MYOD, bHLHc1)
MYF6 (MRF4, bHLHc4)
MYF5 (bHLHc2)
MYOG (bHLHc3)
NR6A1.p2 -0.086 -0.143 NR6A1 (GCNF1, RTR)
SNAI1..3.p2 -0.087 -1.463 SNAI2 (SLUGH1)
SNAI1 (SNA, SLUGH2, SNAH)
SNAI3 (SMUC, Zfp293)
SOX5.p2 -0.088 -0.540 SOX5 (L-SOX5, MGC35153)
GTF2A1,2.p2 -0.089 -0.550 GTF2A1 (TFIIA)
GTF2A2 (TFIIA, HsT18745)
POU3F1..4.p2 -0.092 -0.276 POU3F1 (OCT6, SCIP)
POU3F3 (BRN1, OTF8)
POU3F2 (POUF3, BRN2, OCT7)
POU3F4 (BRN4, OTF9)
NR1H4.p2 -0.093 -0.457 NR1H4 (FXR, RIP14, HRR1, HRR-1)
NR5A1,2.p2 -0.097 -0.930 NR5A1 (FTZ1, SF-1, ELP, AD4BP)
NR5A2 (FTZ-F1beta, hB1F, LRH-1, FTZ-F1, hB1F-2, B1F2)
GATA1..3.p2 -0.098 -1.688 GATA1 (ERYF1, NFE1)
GATA2 (NFE1B)
GATA3 (HDR)
NFE2L1.p2 -0.100 -1.547 NFE2L1 (NRF1, LCR-F1, FLJ00380, TCF11)
ETS1,2.p2 -0.103 -1.233 ETS2
ETS1 (FLJ10768, ETS-1)
PITX1..3.p2 -0.104 -1.284 PITX2 (IGDS, RS, Brx1, Otlx2, ARP1)
PITX3
PITX1 (PTX1, POTX)
AIRE.p2 -0.107 -0.294 AIRE (PGA1, APS1)
RREB1.p2 -0.108 -2.566 RREB1 (HNT)
LHX3,4.p2 -0.108 -0.487 LHX3
LHX4 (Gsh4)
HOX{A4,D4}.p2 -0.118 -0.772 HOXA4
HOXD4
MYOD1.p2 -0.119 -1.280 MYOD1 (PUM, MYOD, bHLHc1)
HSF1,2.p2 -0.120 -0.886 HSF1 (HSTF1)
HSF2
KLF12.p2 -0.120 -1.971 KLF12 (AP-2rep, HSPC122, AP2REP)
FOXL1.p2 -0.121 -0.785 FOXL1 (FREAC7, FKH6)
RXRA_VDR{dimer}.p2 -0.124 -0.293 VDR (NR1I1)
ZNF423.p2 -0.125 -0.778 ZNF423 (KIAA0760, OAZ, Roaz, Ebfaz, Zfp104)
DBP.p2 -0.127 -1.015 DBP (DABP)
TGIF1.p2 -0.127 -0.768 TGIF1
CDC5L.p2 -0.129 -0.471 CDC5L (PCDC5RP, hCDC5, CEF1)
NKX3-1.p2 -0.132 -0.515 NKX3-1 (NKX3.1, BAPX2)
HNF4A_NR2F1,2.p2 -0.133 -1.338 NR2F1 (EAR-3, COUP-TFI, TCFCOUP1, SVP44)
NR2F2 (COUP-TFII, COUPTFB, SVP40)
HNF4A (NR2A1, HNF4)
FOSL2.p2 -0.135 -0.586 FOSL2 (FRA2, FLJ23306)
VSX1,2.p2 -0.137 -0.183 VSX2 (RET1)
VSX1 (PPD)
TBP.p2 -0.140 -0.630 TBP (TFIID)
ONECUT1,2.p2 -0.149 -0.659 ONECUT2 (OC-2)
ONECUT1 (HNF-6)
FOXA2.p3 -0.161 -0.779 FOXA2
GFI1B.p2 -0.161 -0.491 GFI1B
SMAD1..7,9.p2 -0.166 -1.324 SMAD5 (Dwfc, JV5-1)
SMAD1 (MADR1, JV4-1)
SMAD3 (JV15-2, HsT17436)
SMAD4 (DPC4)
SMAD2 (MADR2, JV18-1)
SMAD6 (HsT17432)
SMAD7
SMAD9
ALX1.p2 -0.172 -0.690 ALX1
ZNF238.p2 -0.176 -0.663 ZNF238 (C2H2-171, TAZ-1, RP58, ZBTB18)
PPARG.p2 -0.179 -0.374 PPARG (PPARG1, PPARG2, NR1C3, PPARgamma)
EOMES.p2 -0.179 -0.706 EOMES (TBR2)
CEBPA,B_DDIT3.p2 -0.186 -0.456 DDIT3 (CHOP10, GADD153, CHOP)
CEBPA (C/EBP-alpha)
CEBPB (LAP, CRP2, NFIL6, IL6DBP)
T.p2 -0.191 -0.367 T
TLX1..3_NFIC{dimer}.p2 -0.213 -1.038 TLX1
TLX3 (RNX)
NANOG{mouse}.p2 -0.228 -0.725 NANOG (FLJ12581, FLJ40451)
RUNX1..3.p2 -0.228 -1.573 RUNX1 (PEBP2A2, AMLCR1)
RUNX3 (AML2, PEBP2A3)
RUNX2 (AML3, PEBP2A1, PEBP2aA1)
POU6F1.p2 -0.245 -0.680 POU6F1 (BRN5, MPOU, TCFB1)
ARID5B.p2 -0.257 -0.618 ARID5B (FLJ21150, MRF2)
POU5F1_SOX2{dimer}.p2 -0.267 -0.932 POU5F1 (OCT3, Oct4, MGC22487)
SOX2
EVI1.p2 -0.274 -1.546 EVI1 (MDS1-EVI1, PRDM3)
POU1F1.p2 -0.276 -1.143 POU1F1 (GHF-1)
HNF1A.p2 -0.292 -0.876 HNF1A (HNF1, LFB1)
RORA.p2 -0.296 -0.540 RORA (RZRA, ROR1, ROR2, ROR3, NR1F1)
FOX{C1,C2}.p2 -0.299 -0.753 FOXC1 (FREAC3, ARA, IGDA, IHG1)
FOXC2 (MFH-1)
MSX1,2.p2 -0.300 -0.512 MSX1 (HYD1, OFC5)
MSX2 (CRS2, FPP, HOX8, MSH, PFM)
NR3C1.p2 -0.304 -0.870 NR3C1 (GR)
PAX8.p2 -0.313 -0.141 PAX8
HOX{A5,B5}.p2 -0.316 -1.268 HOXB5
HOXA5
HOXA9_MEIS1.p2 -0.345 -0.645 MEIS1
HOXA9
TAL1_TCF{3,4,12}.p2 -0.346 -0.725 TCF3 (E2A, ITF1, MGC129647, MGC129648, bHLHb21)
TCF4 (SEF2-1B, ITF2, bHLHb19)
TAL1 (SCL, bHLHa17)
TCF12 (HEB, HTF4, HsT17266, bHLHb20)
GATA6.p2 -0.349 -1.393 GATA6
HAND1,2.p2 -0.394 -1.462 HAND1 (eHand, Thing1, Hxt, bHLHa27)
HAND2 (dHand, Thing2, Hed, bHLHa26)
PAX6.p2 -0.424 -0.505 PAX6 (D11S812E, AN, WAGR)
FOXP3.p2 -0.463 -1.030 FOXP3 (JM2, XPID, AIID, PIDX, DIETER, SCURFIN)
NKX2-1,4.p2 -0.481 -0.959 NKX2-1 (TTF-1)
NKX2-4 (NKX2.4)
EN1,2.p2 -0.493 -1.924 EN1
EN2
AR.p2 -0.570 -0.752 AR (AIS, NR3C4, SMAX1, HUMARA)
REST.p3 -1.048 -2.671 REST (NRSF, XBR)
PAX3,7.p2 -1.876 -0.764 PAX7 (Hup1)
PAX3 (HUP2)