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Motif ID: SREBF1,2.p2

Z-value: 1.131

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_-_47604930	2.773	NM_001143781	FKBP11	FK506 binding protein 11, 19 kDa
chr22_+_34107087	2.535		HMOX1	heme oxygenase (decycling) 1
chr13_+_112999538	2.518		LAMP1	lysosomal-associated membrane protein 1
chr9_-_37566248	2.347	NM_012166	FBXO10	F-box protein 10
chr13_+_112999590	2.251		LAMP1	lysosomal-associated membrane protein 1
chr13_+_112999462	2.207	NM_005561	LAMP1	lysosomal-associated membrane protein 1
chr10_-_14090459	2.102		FRMD4A	FERM domain containing 4A
chr19_+_54149941	2.077		BAX	BCL2-associated X protein
chr19_+_54149963	2.070		BAX	BCL2-associated X protein
chr19_+_54149843	1.987	NM_004324 NM_138761 NM_138763 NM_138764	BAX	BCL2-associated X protein
chr12_+_52733927	1.876	NM_153633	HOXC4 HOXC6	homeobox C4 homeobox C6
chr13_-_31900218	1.779	NM_001079691 NM_052818	N4BP2L1	NEDD4 binding protein 2-like 1
chr14_-_93512818	1.761		ASB2	ankyrin repeat and SOCS box containing 2
chr22_+_34107051	1.711	NM_002133	HMOX1	heme oxygenase (decycling) 1
chr13_-_32757835	1.698	NM_178006	STARD13	StAR-related lipid transfer (START) domain containing 13
chr7_-_29995809	1.622	NM_001145515 NM_014766 NM_001145513	SCRN1	secernin 1
chr11_+_9642226	1.560		SWAP70	SWAP switching B-cell complex 70kDa subunit
chr11_+_9642200	1.520	NM_015055	SWAP70	SWAP switching B-cell complex 70kDa subunit
chr13_+_48582389	1.520	NM_014923	FNDC3A	fibronectin type III domain containing 3A
chr10_-_98021144	1.475	NM_001114094 NM_013314	BLNK	B-cell linker
chr11_+_9642182	1.447		SWAP70	SWAP switching B-cell complex 70kDa subunit
chr10_+_106018915	1.440		GSTO2	glutathione S-transferase omega 2
chr11_+_9642229	1.432		SWAP70	SWAP switching B-cell complex 70kDa subunit
chr12_-_57600564	1.416		LRIG3	leucine-rich repeats and immunoglobulin-like domains 3
chr9_-_21984329	1.403		CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr19_+_55614006	1.401	NM_003121	SPIB	Spi-B transcription factor (Spi-1/PU.1 related)
chr13_-_49057629	1.394		RCBTB1	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr9_-_21984414	1.386	NM_058195	CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr9_-_21984379	1.382		CDKN2A	cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr8_+_75066117	1.380	NM_001195797 NM_015364	LY96	lymphocyte antigen 96
chr1_-_197173159	1.367		LOC100131234	familial acute myelogenous leukemia related factor
chr16_+_639278	1.360	NM_145294	WDR90	WD repeat domain 90
chr18_+_54958095	1.354	NM_033280	SEC11C	SEC11 homolog C (S. cerevisiae)
chr20_-_4743768	1.353	NM_170774	RASSF2	Ras association (RalGDS/AF-6) domain family member 2
chr13_-_49057707	1.346	NM_018191	RCBTB1	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr3_-_126414252	1.344	NM_024628	SLC12A8	solute carrier family 12 (potassium/chloride transporters), member 8
chr12_-_57600336	1.329	NM_153377	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3
chr18_+_54682261	1.305		ZNF532	zinc finger protein 532
chr19_-_15436333	1.283	NM_022904	RASAL3	RAS protein activator like 3
chr3_-_113763449	1.278		ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)
chr19_-_52710129	1.255	NM_003827	NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha
chr3_-_113763454	1.248		ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)
chr12_+_56284867	1.240	NM_178502	DTX3	deltex homolog 3 (Drosophila)
chrX_+_128741578	1.228		SASH3	SAM and SH3 domain containing 3
chr11_-_60475558	1.223	NM_016582	SLC15A3	solute carrier family 15, member 3
chr3_-_49370755	1.217	NM_000581 NM_201397	GPX1	glutathione peroxidase 1
chr1_+_148521852	1.214	NM_144697	C1orf51	chromosome 1 open reading frame 51
chr3_+_44878380	1.184	NM_144638	TMEM42	transmembrane protein 42
chr7_-_27162688	1.181	NM_006896	HOXA7	homeobox A7
chr3_-_49370682	1.181		GPX1	glutathione peroxidase 1
chr11_+_120828275	1.175		SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr3_-_113763425	1.172		ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)
chrX_+_128741562	1.160	NM_018990	SASH3	SAM and SH3 domain containing 3
chr16_+_28893525	1.154	NM_001142448 NM_001142449 NM_001142450 NM_001142451 NM_032038	SPIN1 SPNS1	spindlin 1 spinster homolog 1 (Drosophila)
chrX_+_102749489	1.151	NM_001006933 NM_032926	TCEAL3	transcription elongation factor A (SII)-like 3
chr16_+_55580910	1.137	NM_032206	NLRC5	NLR family, CARD domain containing 5
chrX_-_114703273	1.101
chr12_+_54396118	1.096		BLOC1S1	biogenesis of lysosomal organelles complex-1, subunit 1
chr5_-_150517499	1.092		ANXA6	annexin A6
chr3_-_113763217	1.091		ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)
chr17_-_41018291	1.084
chr11_+_120828058	1.076	NM_003105	SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr3_+_113763561	1.073	NM_017945	SLC35A5	solute carrier family 35, member A5
chr22_+_40724674	1.066	NM_152613	WBP2NL	WBP2 N-terminal like
chr9_+_6747919	1.031		KDM4C	lysine (K)-specific demethylase 4C
chr1_-_152797707	1.026	NM_017582	UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr5_-_150517454	1.025		ANXA6	annexin A6
chr17_-_7078446	1.016	NM_004422	DVL2	dishevelled, dsh homolog 2 (Drosophila)
chr12_-_44949046	1.011		SLC38A1	solute carrier family 38, member 1
chr1_-_24386324	1.005	NM_170743 NM_173064 NM_173065	IL28RA	interleukin 28 receptor, alpha (interferon, lambda receptor)
chr3_+_113763601	1.000		SLC35A5	solute carrier family 35, member A5
chr1_-_152797760	0.983		UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr6_+_139391511	0.977	NM_021243	C6orf115	chromosome 6 open reading frame 115
chr14_-_67353046	0.970	NM_015346	ZFYVE26	zinc finger, FYVE domain containing 26
chr14_+_44501083	0.969	NM_015091	FAM179B	family with sequence similarity 179, member B
chr12_+_54396099	0.955		BLOC1S1-RDH5 BLOC1S1	BLOC1S1-RDH5 read-through transcript biogenesis of lysosomal organelles complex-1, subunit 1
chr19_-_52709975	0.954		NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha
chr17_-_3407780	0.948		TRPV3	transient receptor potential cation channel, subfamily V, member 3
chr7_+_17304707	0.947	NM_001621	AHR	aryl hydrocarbon receptor
chr11_+_59979857	0.946	NM_021950 NM_152866	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr10_+_51497716	0.941		FAM21A	family with sequence similarity 21, member A
chr12_+_64869181	0.939	NM_001142523 NM_007199	IRAK3	interleukin-1 receptor-associated kinase 3
chr2_+_241174803	0.937	NM_023083 NM_023085	CAPN10	calpain 10
chr7_+_27102508	0.935
chr19_+_10625896	0.932	NM_001137673 NM_004516 NM_012218 NM_017620 NM_153464	ILF3	interleukin enhancer binding factor 3, 90kDa
chr2_+_219751207	0.918		FAM134A	family with sequence similarity 134, member A
chr17_-_33043514	0.917	NM_001163544 NM_001163545 NM_001163546 NM_001163547 NM_007247 NM_080550 NM_198882	SYNRG	synergin, gamma
chrX_+_55760774	0.916	NM_006064 NM_016656	RRAGB	Ras-related GTP binding B
chr8_+_109525050	0.915		TTC35	tetratricopeptide repeat domain 35
chr4_+_91267706	0.912	NM_001145065	FAM190A	family with sequence similarity 190, member A
chr1_-_152797767	0.899		UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr1_+_234372454	0.888	NM_003272	GPR137B	G protein-coupled receptor 137B
chr2_+_219751192	0.887		FAM134A	family with sequence similarity 134, member A
chr19_-_52710089	0.886		NAPA	N-ethylmaleimide-sensitive factor attachment protein, alpha
chr8_+_109525010	0.879	NM_014673	TTC35	tetratricopeptide repeat domain 35
chr12_+_102982365	0.875	NM_013320	HCFC2	host cell factor C2
chr7_-_29996429	0.868	NM_001145514	SCRN1	secernin 1
chr16_-_66827449	0.865	NM_024939	ESRP2	epithelial splicing regulatory protein 2
chr15_+_86983038	0.860	NM_002201	ISG20	interferon stimulated exonuclease gene 20kDa
chr7_+_27102197	0.859
chr12_-_44948976	0.859		SLC38A1	solute carrier family 38, member 1
chr9_-_133574928	0.858	NM_198679	RAPGEF1	Rap guanine nucleotide exchange factor (GEF) 1
chr2_-_196744546	0.850	NM_004226	STK17B	serine/threonine kinase 17b
chr1_+_111544469	0.849
chr3_-_123995216	0.849	NM_024610	HSPBAP1	HSPB (heat shock 27kDa) associated protein 1
chr14_-_93512647	0.842		ASB2	ankyrin repeat and SOCS box containing 2
chr7_-_27102049	0.834	NM_005522 NM_153620	HOXA1	homeobox A1
chr3_+_114733907	0.831	NM_017699	SIDT1	SID1 transmembrane family, member 1
chr14_-_91642641	0.829		ATXN3 ATXN8	ataxin 3 ataxin 8
chr2_+_143603439	0.827		ARHGAP15	Rho GTPase activating protein 15
chr14_-_91642703	0.825	NM_001127696 NM_001127697 NM_001164774 NM_001164776 NM_001164777 NM_001164778 NM_001164779 NM_001164780 NM_001164781 NM_001164782 NM_004993 NM_030660	ATXN3	ataxin 3
chr3_-_113763049	0.823	NM_022488	ATG3	ATG3 autophagy related 3 homolog (S. cerevisiae)
chr2_+_219751230	0.819		FAM134A	family with sequence similarity 134, member A
chr8_+_26296439	0.818	NM_004331	BNIP3L	BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr12_+_54396086	0.816	NM_001487	BLOC1S1	biogenesis of lysosomal organelles complex-1, subunit 1
chr11_-_85457469	0.812		PICALM	phosphatidylinositol binding clathrin assembly protein
chr2_-_219750975	0.811		C2orf24	chromosome 2 open reading frame 24
chr14_-_80757018	0.811	NM_015859	GTF2A1	general transcription factor IIA, 1, 19/37kDa
chr2_-_196744507	0.811		STK17B	serine/threonine kinase 17b
chr6_+_139391570	0.807		C6orf115	chromosome 6 open reading frame 115
chr6_-_84994032	0.804	NM_014895	KIAA1009	KIAA1009
chr12_+_64869271	0.803		IRAK3	interleukin-1 receptor-associated kinase 3
chr11_+_7491789	0.800		PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr2_+_219751145	0.800	NM_024293	FAM134A	family with sequence similarity 134, member A
chr11_+_7491576	0.794	NM_003621	PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr17_-_7078399	0.789		DVL2	dishevelled, dsh homolog 2 (Drosophila)
chr1_-_152797820	0.787		UBE2Q1	ubiquitin-conjugating enzyme E2Q family member 1
chr1_-_42694263	0.779		ZMYND12	zinc finger, MYND-type containing 12
chrX_+_101267315	0.775	NM_080390	TCEAL2	transcription elongation factor A (SII)-like 2
chr17_+_75851984	0.768
chr8_-_81246215	0.761	NM_001025253 NM_005079	TPD52	tumor protein D52
chr17_+_3486753	0.755		CTNS	cystinosis, nephropathic
chr15_-_70455355	0.745	NM_000520	HEXA	hexosaminidase A (alpha polypeptide)
chr12_+_120840829	0.742	NM_001178003 NM_144668	WDR66	WD repeat domain 66
chr10_+_51497660	0.728	NM_001005751	FAM21C FAM21A	family with sequence similarity 21, member C family with sequence similarity 21, member A
chr11_+_120399966	0.726	NM_001130047 NM_152715	TBCEL	tubulin folding cofactor E-like
chr13_-_73605914	0.721	NM_007249	KLF12	Kruppel-like factor 12
chr8_+_98725505	0.716	NM_178812	MTDH	metadherin
chrX_+_72699834	0.710		CHIC1	cysteine-rich hydrophobic domain 1
chr10_-_90332927	0.707	NM_001031709 NM_018363	RNLS	renalase, FAD-dependent amine oxidase
chr7_+_101861007	0.707		ORAI2	ORAI calcium release-activated calcium modulator 2
chr12_+_64869296	0.702		IRAK3	interleukin-1 receptor-associated kinase 3
chr15_-_70455153	0.696		HEXA	hexosaminidase A (alpha polypeptide)
chr19_+_7493436	0.687	NM_020533	MCOLN1	mucolipin 1
chr12_-_119826073	0.681		SPPL3	signal peptide peptidase 3
chr16_-_4528380	0.680	NM_001199054	C16orf5	chromosome 16 open reading frame 5
chr5_-_150517528	0.678	NM_001155	ANXA6	annexin A6
chr3_+_49002774	0.677		P4HTM	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)
chr3_-_11736946	0.674	NM_014667	VGLL4	vestigial like 4 (Drosophila)
chr14_+_19993181	0.673		APEX1	APEX nuclease (multifunctional DNA repair enzyme) 1
chr4_-_47160403	0.671	NM_017845	COMMD8	COMM domain containing 8
chr2_+_227898163	0.671		MFF	mitochondrial fission factor
chr19_+_10625987	0.664		ILF3	interleukin enhancer binding factor 3, 90kDa
chr8_+_98725604	0.664		MTDH	metadherin
chrX_+_102727068	0.657	NM_001006935 NM_001006937 NM_024863	TCEAL4	transcription elongation factor A (SII)-like 4
chr8_+_67507271	0.657	NM_144650	ADHFE1	alcohol dehydrogenase, iron containing, 1
chr8_+_123863075	0.651	NM_014943	ZHX2	zinc fingers and homeoboxes 2
chr1_-_184916044	0.651	NM_000963	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr22_+_23153529	0.651	NM_000675	ADORA2A	adenosine A2a receptor
chr17_+_39778016	0.646	NM_002087	GRN	granulin
chr16_+_68353662	0.644		WWP2	WW domain containing E3 ubiquitin protein ligase 2
chr14_+_23700261	0.644	NM_006084	IRF9	interferon regulatory factor 9
chr17_-_7078304	0.643		DVL2	dishevelled, dsh homolog 2 (Drosophila)
chr11_+_66915997	0.641	NM_004584	RAD9A	RAD9 homolog A (S. pombe)
chr3_+_133619193	0.638	NM_015268	DNAJC13	DnaJ (Hsp40) homolog, subfamily C, member 13
chr8_+_98725670	0.636		MTDH	metadherin
chr4_-_47160476	0.623		COMMD8	COMM domain containing 8
chr14_-_64040072	0.615	NM_006977	ZBTB25	zinc finger and BTB domain containing 25
chr19_-_42098919	0.612	NM_001037232	ZNF829	zinc finger protein 829
chr17_-_71487038	0.608		ACOX1	acyl-CoA oxidase 1, palmitoyl
chr17_+_6856521	0.606	NM_001004333	RNASEK-C17ORF49 RNASEK	RNASEK-C17orf49 read-through transcript ribonuclease, RNase K
chr17_+_63713171	0.601
chr21_+_25856311	0.596		MIR155HG	MIR155 host gene (non-protein coding)
chr19_+_1018536	0.595		HMHA1	histocompatibility (minor) HA-1
chr12_-_9913199	0.595		CLEC2B	C-type lectin domain family 2, member B
chr19_-_10625449	0.595		LOC147727	hypothetical LOC147727
chr8_-_54918325	0.592		ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr10_-_105442868	0.591		SH3PXD2A	SH3 and PX domains 2A
chr14_+_44622916	0.591	NM_017922	PRPF39	PRP39 pre-mRNA processing factor 39 homolog (S. cerevisiae)
chr17_+_39778153	0.589		GRN	granulin
chr7_+_101860958	0.589	NM_001126340 NM_032831	ORAI2	ORAI calcium release-activated calcium modulator 2
chr9_-_139128777	0.585		DPP7	dipeptidyl-peptidase 7
chr17_+_6856676	0.585		RNASEK-C17ORF49 RNASEK	RNASEK-C17orf49 read-through transcript ribonuclease, RNase K
chr6_-_152664906	0.583		SYNE1	spectrin repeat containing, nuclear envelope 1
chr16_+_80370426	0.581	NM_002661	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr17_+_71487080	0.575		C17orf106	chromosome 17 open reading frame 106
chr8_-_54918389	0.573	NM_015941 NM_213619	ATP6V1H	ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
chr3_-_121550767	0.572	NM_001099678	LRRC58	leucine rich repeat containing 58
chr10_+_23768203	0.571	NM_001145373	OTUD1	OTU domain containing 1
chrX_-_100801472	0.571	NM_014782 NM_177949	ARMCX2	armadillo repeat containing, X-linked 2
chr16_-_66072477	0.566	NM_004691	ATP6V0D1	ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1
chr15_-_71712711	0.564	NM_001161363 NM_001161364 NM_012428 NM_017455	NPTN	neuroplastin
chr10_-_105427898	0.564		SH3PXD2A	SH3 and PX domains 2A
chr6_-_80713589	0.560	NM_022726	ELOVL4	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4
chr12_+_14409875	0.560	NM_018179	ATF7IP	activating transcription factor 7 interacting protein
chr17_+_73638430	0.553	NM_152468	TMC8	transmembrane channel-like 8
chr17_+_7152417	0.553	NM_001143762	EIF5A	eukaryotic translation initiation factor 5A
chr4_+_113958652	0.546	NM_001127493	ANK2	ankyrin 2, neuronal
chr14_-_92869124	0.545	NM_001002860 NM_018167	BTBD7	BTB (POZ) domain containing 7
chr8_-_82186832	0.544	NM_018440	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.34	2.23e-03	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
5.22	8.16e-03	GO:0015682	ferric iron transport
5.22	8.16e-03	GO:0033572	transferrin transport
1.10	1.03e-02	GO:0009987	cellular process
1.28	1.30e-02	GO:0006807	nitrogen compound metabolic process
1.18	1.36e-02	GO:0044237	cellular metabolic process
1.28	2.87e-02	GO:0034641	cellular nitrogen compound metabolic process

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.14	1.86e-09	GO:0005622	intracellular
1.30	4.10e-09	GO:0044446	intracellular organelle part
1.29	5.40e-09	GO:0044422	organelle part
1.14	9.84e-09	GO:0044424	intracellular part
1.19	5.14e-08	GO:0043227	membrane-bounded organelle
1.18	8.76e-08	GO:0043231	intracellular membrane-bounded organelle
1.19	8.95e-08	GO:0005737	cytoplasm
1.16	3.12e-07	GO:0043226	organelle
1.25	4.50e-07	GO:0044444	cytoplasmic part
1.16	6.39e-07	GO:0043229	intracellular organelle
1.62	2.99e-06	GO:0005654	nucleoplasm
1.44	5.25e-06	GO:0031974	membrane-enclosed lumen
1.44	7.16e-06	GO:0070013	intracellular organelle lumen
1.43	8.89e-06	GO:0043233	organelle lumen
1.42	4.08e-05	GO:0044428	nuclear part
1.47	4.91e-05	GO:0031981	nuclear lumen
1.73	2.85e-04	GO:0044451	nucleoplasm part
2.08	1.12e-03	GO:0005773	vacuole
1.37	2.23e-03	GO:0005829	cytosol
1.19	2.33e-03	GO:0005634	nucleus
2.47	7.00e-03	GO:0005774	vacuolar membrane
1.25	8.45e-03	GO:0032991	macromolecular complex
3.56	1.02e-02	GO:0016605	PML body
5.70	1.46e-02	GO:0033176	proton-transporting V-type ATPase complex
2.36	1.59e-02	GO:0044437	vacuolar part
1.05	1.84e-02	GO:0044464	cell part
1.05	1.88e-02	GO:0005623	cell
1.96	3.75e-02	GO:0000323	lytic vacuole
1.96	3.75e-02	GO:0005764	lysosome
1.25	3.81e-02	GO:0043234	protein complex

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.18	8.57e-05	GO:0005515	protein binding
1.09	1.60e-03	GO:0005488	binding
6.33	8.21e-03	GO:0046961	proton-transporting ATPase activity, rotational mechanism
2.63	2.51e-02	GO:0015631	tubulin binding
1.83	2.80e-02	GO:0003712	transcription cofactor activity
1.83	3.00e-02	GO:0000988	protein binding transcription factor activity
1.83	3.00e-02	GO:0000989	transcription factor binding transcription factor activity