Motif ID: SREBF1,2.p2

Z-value: 1.131


Transcription factors associated with SREBF1,2.p2:

Gene SymbolEntrez IDGene Name
SREBF1 6720 sterol regulatory element binding transcription factor 1
SREBF2 6721 sterol regulatory element binding transcription factor 2

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SREBF1chr17_-_17681013-0.591.7e-02Click!
SREBF2chr22_+_405592140.097.5e-01Click!


Activity profile for motif SREBF1,2.p2.

activity profile for motif SREBF1,2.p2


Sorted Z-values histogram for motif SREBF1,2.p2

Sorted Z-values for motif SREBF1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SREBF1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_47604930 2.773 NM_001143781
 FKBP11
FK506 binding protein 11, 19 kDa
chr22_+_34107087 2.535 HMOX1
heme oxygenase (decycling) 1
chr13_+_112999538 2.518 LAMP1
lysosomal-associated membrane protein 1
chr9_-_37566248 2.347 NM_012166
 FBXO10
F-box protein 10
chr13_+_112999590 2.251 LAMP1
lysosomal-associated membrane protein 1
chr13_+_112999462 2.207 NM_005561
 LAMP1
lysosomal-associated membrane protein 1
chr10_-_14090459 2.102 FRMD4A
FERM domain containing 4A
chr19_+_54149941 2.077 BAX
BCL2-associated X protein
chr19_+_54149963 2.070 BAX
BCL2-associated X protein
chr19_+_54149843 1.987 NM_004324
NM_138761
NM_138763
NM_138764
 BAX



BCL2-associated X protein



chr12_+_52733927 1.876 NM_153633
 HOXC4
HOXC6
homeobox C4
homeobox C6
chr13_-_31900218 1.779 NM_001079691
NM_052818
 N4BP2L1

NEDD4 binding protein 2-like 1

chr14_-_93512818 1.761 ASB2
ankyrin repeat and SOCS box containing 2
chr22_+_34107051 1.711 NM_002133
 HMOX1
heme oxygenase (decycling) 1
chr13_-_32757835 1.698 NM_178006
 STARD13
StAR-related lipid transfer (START) domain containing 13
chr7_-_29995809 1.622 NM_001145515
NM_014766
NM_001145513
 SCRN1


secernin 1


chr11_+_9642226 1.560 SWAP70
SWAP switching B-cell complex 70kDa subunit
chr11_+_9642200 1.520 NM_015055
 SWAP70
SWAP switching B-cell complex 70kDa subunit
chr13_+_48582389 1.520 NM_014923
 FNDC3A
fibronectin type III domain containing 3A
chr10_-_98021144 1.475 NM_001114094
NM_013314
 BLNK

B-cell linker


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
5.22 8.16e-03 GO:0015682 ferric iron transport
5.22 8.16e-03 GO:0033572 transferrin transport
1.34 2.23e-03 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.28 1.30e-02 GO:0006807 nitrogen compound metabolic process
1.28 2.87e-02 GO:0034641 cellular nitrogen compound metabolic process
1.18 1.36e-02 GO:0044237 cellular metabolic process
1.10 1.03e-02 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 30 entries
enrichment   p-value GO term description
5.70 1.46e-02 GO:0033176 proton-transporting V-type ATPase complex
3.56 1.02e-02 GO:0016605 PML body
2.47 7.00e-03 GO:0005774 vacuolar membrane
2.36 1.59e-02 GO:0044437 vacuolar part
2.08 1.12e-03 GO:0005773 vacuole
1.96 3.75e-02 GO:0000323 lytic vacuole
1.96 3.75e-02 GO:0005764 lysosome
1.73 2.85e-04 GO:0044451 nucleoplasm part
1.62 2.99e-06 GO:0005654 nucleoplasm
1.47 4.91e-05 GO:0031981 nuclear lumen
1.44 5.25e-06 GO:0031974 membrane-enclosed lumen
1.44 7.16e-06 GO:0070013 intracellular organelle lumen
1.43 8.89e-06 GO:0043233 organelle lumen
1.42 4.08e-05 GO:0044428 nuclear part
1.37 2.23e-03 GO:0005829 cytosol
1.30 4.10e-09 GO:0044446 intracellular organelle part
1.29 5.40e-09 GO:0044422 organelle part
1.25 4.50e-07 GO:0044444 cytoplasmic part
1.25 8.45e-03 GO:0032991 macromolecular complex
1.25 3.81e-02 GO:0043234 protein complex

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
6.33 8.21e-03 GO:0046961 proton-transporting ATPase activity, rotational mechanism
2.63 2.51e-02 GO:0015631 tubulin binding
1.83 2.80e-02 GO:0003712 transcription cofactor activity
1.83 3.00e-02 GO:0000988 protein binding transcription factor activity
1.83 3.00e-02 GO:0000989 transcription factor binding transcription factor activity
1.18 8.57e-05 GO:0005515 protein binding
1.09 1.60e-03 GO:0005488 binding