Motif ID: POU3F1..4.p2

Z-value: 1.479


Transcription factors associated with POU3F1..4.p2:

Gene SymbolEntrez IDGene Name
POU3F1 5453 POU class 3 homeobox 1
POU3F2 5454 POU class 3 homeobox 2
POU3F3 5455 POU class 3 homeobox 3
POU3F4 5456 POU class 3 homeobox 4

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
POU3F2chr6_+_993893000.674.3e-03Click!
POU3F1chr1_-_382850330.282.9e-01Click!
POU3F3chr2_+_1048381770.136.2e-01Click!
POU3F4chrX_+_82649924-0.058.4e-01Click!


Activity profile for motif POU3F1..4.p2.

activity profile for motif POU3F1..4.p2


Sorted Z-values histogram for motif POU3F1..4.p2

Sorted Z-values for motif POU3F1..4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU3F1..4.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_44037332 4.556 NM_018952
HOXB6
homeobox B6
chr21_-_35343331 3.628 RUNX1
runt-related transcription factor 1
chrX_+_65300803 2.804 NM_001130860
NM_014799
HEPH

hephaestin

chr1_-_171441234 2.543 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr21_-_35343065 2.382 RUNX1
runt-related transcription factor 1
chr8_+_107807415 2.316 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr3_-_170348215 2.312 NM_001164000
MECOM
MDS1 and EVI1 complex locus
chrX_+_100692071 2.103 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr3_+_25444837 2.042 NM_000965
RARB
retinoic acid receptor, beta
chr12_-_52939636 1.960 NM_001127321
CBX5
chromobox homolog 5
chr6_-_131333173 1.889 EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr15_-_53996597 1.869 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr10_-_75080784 1.757 NM_024875
SYNPO2L
synaptopodin 2-like
chr3_+_25444753 1.719 NM_016152
RARB
retinoic acid receptor, beta
chr12_-_52939584 1.712 NM_001127322
CBX5
chromobox homolog 5
chr2_+_151922350 1.681 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr1_+_176577228 1.589 NM_004841
RASAL2
RAS protein activator like 2
chr2_-_162808123 1.576 NM_004460
FAP
fibroblast activation protein, alpha
chr18_-_51219880 1.512 TCF4
transcription factor 4
chr2_-_110665188 1.512 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr4_+_169654742 1.455 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr11_+_65027721 1.450


chr9_+_74956601 1.419 ANXA1
annexin A1
chr1_+_66570683 1.401 PDE4B
phosphodiesterase 4B, cAMP-specific
chr2_+_189547358 1.327 COL3A1
collagen, type III, alpha 1
chrX_+_102471769 1.322 NM_152278
TCEAL7
transcription elongation factor A (SII)-like 7
chr9_+_74956614 1.303 ANXA1
annexin A1
chr2_+_189547377 1.244 COL3A1
collagen, type III, alpha 1
chr9_+_74956494 1.220 NM_000700
ANXA1
annexin A1
chr12_-_69317441 1.206 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr12_-_90029328 1.193 LUM
lumican
chr12_-_9913199 1.186 CLEC2B
C-type lectin domain family 2, member B
chr5_-_119768430 1.131


chrX_+_106758395 1.125 PRPS1
phosphoribosyl pyrophosphate synthetase 1
chrX_-_33139349 1.088 NM_004006
DMD
dystrophin
chr6_+_121798443 1.053 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr1_+_157246305 1.051 NM_005531
IFI16
interferon, gamma-inducible protein 16
chr10_-_69095362 1.005 NM_001127384
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr8_-_13018123 1.001 NM_001164271
DLC1
deleted in liver cancer 1
chr2_+_108571209 1.000 LIMS1
LIM and senescent cell antigen-like domains 1
chrX_+_106758309 0.923 NM_002764
PRPS1
phosphoribosyl pyrophosphate synthetase 1
chr13_+_100902942 0.917 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr2_+_189547323 0.909 NM_000090
COL3A1
collagen, type III, alpha 1
chr13_-_77390907 0.900 NM_001122659
NM_003991
EDNRB

endothelin receptor type B

chr12_-_9913724 0.900 NM_005127
CLEC2B
C-type lectin domain family 2, member B
chr7_+_129634935 0.899 NM_145268
C7orf45
chromosome 7 open reading frame 45
chr8_-_13416554 0.891 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chr2_-_190635566 0.880 NM_005259
MSTN
myostatin
chr5_-_156935317 0.880 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr6_-_46997579 0.865 NM_001098518
GPR116
G protein-coupled receptor 116
chr9_+_91409746 0.862 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr3_+_11242666 0.858 NM_001098211
HRH1
histamine receptor H1
chr6_-_152744022 0.838 SYNE1
spectrin repeat containing, nuclear envelope 1
chr5_+_34720368 0.835 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr1_-_143706196 0.830 PDE4DIP
phosphodiesterase 4D interacting protein
chr7_-_11838260 0.811 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr5_-_156935283 0.804


chrX_+_65299157 0.800 NM_138737
HEPH
hephaestin
chr5_-_150306298 0.785 ZNF300P1
zinc finger protein 300 pseudogene 1
chrX_+_67830204 0.784 NM_001142504
STARD8
StAR-related lipid transfer (START) domain containing 8
chr1_+_51208499 0.774 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr11_-_1975265 0.774 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr1_-_202595666 0.768 NM_014935
PLEKHA6
pleckstrin homology domain containing, family A member 6
chr1_-_240228987 0.765 NM_001004343
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr6_-_152744143 0.749 SYNE1
spectrin repeat containing, nuclear envelope 1
chr5_+_86712376 0.740


chr2_-_144994038 0.737 ZEB2
zinc finger E-box binding homeobox 2
chr11_+_71580816 0.729 NM_016729
FOLR1
folate receptor 1 (adult)
chr2_-_198248828 0.729 NM_144629
RFTN2
raftlin family member 2
chr1_+_78243181 0.725 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr15_+_37330176 0.715 NM_207445
C15orf54
chromosome 15 open reading frame 54
chrX_+_134482212 0.708 NM_182540
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr11_+_5667494 0.708 NM_006074
TRIM22
tripartite motif containing 22
chr6_-_139654807 0.700 NM_153235
TXLNB
taxilin beta
chr11_+_33306652 0.697 HIPK3
homeodomain interacting protein kinase 3
chr1_-_143708467 0.692 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr6_+_116939500 0.681 NM_153711
FAM26E
family with sequence similarity 26, member E
chrX_+_47999740 0.677 NM_005635
SSX1
synovial sarcoma, X breakpoint 1
chr7_+_91762227 0.676


chr8_+_1980564 0.675 NM_003970
MYOM2
myomesin (M-protein) 2, 165kDa
chr1_-_167663278 0.669 NM_021179
C1orf114
chromosome 1 open reading frame 114
chr6_+_28342766 0.664 NM_001023560
NM_001111039
NM_152736
ZNF187


zinc finger protein 187


chr3_+_100840129 0.658 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr6_+_7347878 0.658 NM_153005
RIOK1
RIO kinase 1 (yeast)
chr4_-_54119102 0.644 LNX1
ligand of numb-protein X 1
chr8_+_67201684 0.631 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr13_+_47776026 0.630 RB1
retinoblastoma 1
chr19_-_60241424 0.629 NM_001083899
NM_016363
GP6

glycoprotein VI (platelet)

chr2_+_108571177 0.629 NM_004987
LIMS1
LIM and senescent cell antigen-like domains 1
chr5_-_75954807 0.628 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr12_+_102859354 0.625 HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr22_-_48437081 0.620 C22orf34
chromosome 22 open reading frame 34
chr9_+_18464138 0.614 ADAMTSL1
ADAMTS-like 1
chr11_+_65026382 0.613


chr1_-_143706300 0.608 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chr1_-_171286634 0.603 NM_005092
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr15_+_90738108 0.598 NM_006011
ST8SIA2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr4_+_124063660 0.594 NM_145207
SPATA5
spermatogenesis associated 5
chr12_-_16650687 0.592 LMO3
LIM domain only 3 (rhombotin-like 2)
chr18_-_63333487 0.583 DSEL
dermatan sulfate epimerase-like
chr15_-_68781662 0.581 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr8_+_39890484 0.575 NM_002164
IDO1
indoleamine 2,3-dioxygenase 1
chr1_-_41398126 0.573 NM_001172222
SCMH1
sex comb on midleg homolog 1 (Drosophila)
chr12_-_8110268 0.568 C3AR1
complement component 3a receptor 1
chr13_-_59223074 0.565


chr12_+_54172413 0.554 NM_001005519
OR6C68
olfactory receptor, family 6, subfamily C, member 68
chr7_-_20223467 0.552 NM_182762
MACC1
metastasis associated in colon cancer 1
chr1_-_143706265 0.540 PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_229071957 0.539 NM_001136494
C1orf198
chromosome 1 open reading frame 198
chr17_+_29606408 0.532 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr12_+_79127363 0.532 NM_173591
OTOGL
otogelin-like
chr4_-_54119123 0.532 LNX1
ligand of numb-protein X 1
chr5_+_149320480 0.529 NM_000112
SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr1_-_89364273 0.518 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr8_-_72437020 0.512 NM_000503
EYA1
eyes absent homolog 1 (Drosophila)
chrX_+_67830215 0.511 STARD8
StAR-related lipid transfer (START) domain containing 8
chr11_-_71458739 0.497 NUMA1
nuclear mitotic apparatus protein 1
chr12_-_8110196 0.483 NM_004054
C3AR1
complement component 3a receptor 1
chr11_-_1974398 0.482 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chrX_+_99785818 0.480 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr1_+_190394214 0.473 NM_130782
RGS18
regulator of G-protein signaling 18
chr13_-_77391525 0.471


chr11_+_113280727 0.467 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chr8_-_17599438 0.465 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr7_-_32496497 0.463 NM_012322
LSM5
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr8_-_6407882 0.459 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr7_-_92615593 0.456 NM_152703
SAMD9L
sterile alpha motif domain containing 9-like
chr7_+_102775309 0.454 NM_002803
PSMC2
proteasome (prosome, macropain) 26S subunit, ATPase, 2
chr4_-_54119159 0.454 NM_032622
LNX1
ligand of numb-protein X 1
chr12_-_242255 0.451 NM_001190997
NM_016615
SLC6A13

solute carrier family 6 (neurotransmitter transporter, GABA), member 13

chr1_+_231007260 0.436 NM_019090
KIAA1383
KIAA1383
chr4_-_152368492 0.435 SH3D19
SH3 domain containing 19
chr12_+_52806103 0.428 LOC400043
hypothetical LOC400043
chr15_+_76171981 0.427 NM_001101404
SH2D7
SH2 domain containing 7
chr4_-_81213333 0.426 NM_001145794
NM_058172
ANTXR2

anthrax toxin receptor 2

chr4_-_90197140 0.424 NM_014883
FAM13A
family with sequence similarity 13, member A
chr1_-_143786993 0.421 NM_022359
PDE4DIP
phosphodiesterase 4D interacting protein
chr1_+_32438788 0.419 NM_024296
CCDC28B
coiled-coil domain containing 28B
chr5_-_140875591 0.417 DIAPH1
diaphanous homolog 1 (Drosophila)
chr19_-_51608665 0.417 NM_032040
CCDC8
coiled-coil domain containing 8
chr17_-_45629401 0.415


chr3_-_147696411 0.414 NM_020359
PLSCR2
phospholipid scramblase 2
chr7_+_106292975 0.413 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr7_+_143263191 0.411 NM_001004685
OR2F2
olfactory receptor, family 2, subfamily F, member 2
chr13_-_24644304 0.411 FAM123A
family with sequence similarity 123A
chr1_-_68688219 0.409 NM_000329
RPE65
retinal pigment epithelium-specific protein 65kDa
chr4_-_109307325 0.409 NM_001166119
LEF1
lymphoid enhancer-binding factor 1
chr4_-_145281237 0.408 NM_002099
GYPA
glycophorin A (MNS blood group)
chr3_+_123095860 0.408 NM_001145998
NM_021082
SLC15A2

solute carrier family 15 (H+/peptide transporter), member 2

chr12_-_47869134 0.398 TUBA1A
tubulin, alpha 1a
chr1_+_559129 0.397


chr3_-_158704056 0.395 NM_001167915
NM_001167916
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr11_-_130291584 0.395 NM_014758
SNX19
sorting nexin 19
chr17_+_65582981 0.392 NM_018658
NM_170741
KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr1_+_66772393 0.391 NM_032291
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr1_+_239882202 0.387 NM_144625
WDR64
WD repeat domain 64
chr7_+_106292932 0.381 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr11_-_33139449 0.381 NM_001033505
NM_001033506
NM_001326
CSTF3


cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa


chr6_+_130381408 0.380 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr6_+_49575629 0.379 NM_001010904
GLYATL3
glycine-N-acyltransferase-like 3
chr9_-_110815542 0.376 NM_003798
CTNNAL1
catenin (cadherin-associated protein), alpha-like 1
chr6_+_17390910 0.371 NM_153020
RBM24
RNA binding motif protein 24
chr14_-_62638336 0.370 NM_172376
KCNH5
potassium voltage-gated channel, subfamily H (eag-related), member 5
chr4_+_166097579 0.368 C4orf39
chromosome 4 open reading frame 39
chr14_-_80477783 0.367 C14orf145
chromosome 14 open reading frame 145
chr2_-_63518589 0.364 NM_001042692
WDPCP
WD repeat containing planar cell polarity effector
chr5_+_140772691 0.362 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr12_-_15706340 0.362 EPS8
epidermal growth factor receptor pathway substrate 8
chr3_-_101077605 0.359 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr2_-_99284070 0.358 NM_174898
LYG1
lysozyme G-like 1
chr1_-_152394215 0.357 NM_001159484
NM_207308
NUP210L

nucleoporin 210kDa-like

chr11_-_130291527 0.356 SNX19
sorting nexin 19
chr5_+_52892217 0.355 NM_002495
NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr16_+_14187965 0.350 MKL2
MKL/myocardin-like 2
chr14_-_99911679 0.348 NM_004184
NM_213646
WARS

tryptophanyl-tRNA synthetase

chr12_-_101115677 0.348 NM_002674
PMCH
pro-melanin-concentrating hormone
chr1_+_231007734 0.346 KIAA1383
KIAA1383
chr2_-_202271598 0.346 NM_033066
MPP4
membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
chr21_-_14677310 0.343 NM_006948
HSPA13
heat shock protein 70kDa family, member 13
chr4_+_2853434 0.336 ADD1
adducin 1 (alpha)
chr3_+_12367993 0.336 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr3_+_185377341 0.333 AP2M1
adaptor-related protein complex 2, mu 1 subunit
chr1_-_242073094 0.332 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr6_-_49942147 0.331 NM_001131
NM_170609
CRISP1

cysteine-rich secretory protein 1

chr7_-_16471817 0.329 NM_015464
SOSTDC1
sclerostin domain containing 1
chr5_+_52892229 0.328 NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr3_+_185355909 0.326 DVL3
dishevelled, dsh homolog 3 (Drosophila)
chr5_-_98290117 0.323 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chrX_+_54850832 0.323 NM_177433
MAGED2
melanoma antigen family D, 2
chr10_-_50066386 0.317 NM_001010863
C10orf128
chromosome 10 open reading frame 128
chr11_+_22316242 0.317 NM_020346
SLC17A6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr20_-_42249146 0.313 JPH2
junctophilin 2
chr11_-_5037432 0.313 NM_001005164
OR52E2
olfactory receptor, family 52, subfamily E, member 2
chr9_-_106407728 0.310 NM_001004481
OR13C2
olfactory receptor, family 13, subfamily C, member 2
chr12_-_55758840 0.309 NM_001130963
NM_015257
TMEM194A

transmembrane protein 194A

chr2_+_223625105 0.309 NM_080671
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr2_+_108590032 0.309 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr17_-_1211263 0.305 YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr12_+_21417068 0.305 NM_000415
IAPP
islet amyloid polypeptide
chr10_-_16604009 0.303 NM_001010908
C1QL3
complement component 1, q subcomponent-like 3

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.39 2.27e-05 GO:0071944 cell periphery
1.39 3.05e-05 GO:0005886 plasma membrane

Nothing significant found in function category.