Motif ID: ZIC1..3.p2

Z-value: 1.685


Transcription factors associated with ZIC1..3.p2:

Gene SymbolEntrez IDGene Name
ZIC1 7545 Zic family member 1 (odd-paired homolog, Drosophila)
ZIC2 7546 Zic family member 2 (odd-paired homolog, Drosophila)
ZIC3 7547 Zic family member 3 (odd-paired homolog, Drosophila)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZIC1chr3_+_1486105160.523.9e-02Click!
ZIC2chr13_+_99432258-0.495.1e-02Click!
ZIC3chrX_+_1364763530.467.6e-02Click!


Activity profile for motif ZIC1..3.p2.

activity profile for motif ZIC1..3.p2


Sorted Z-values histogram for motif ZIC1..3.p2

Sorted Z-values for motif ZIC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZIC1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_85169615 4.596 NM_005250
FOXL1
forkhead box L1
chr3_+_160964574 4.360 SCHIP1
schwannomin interacting protein 1
chr3_-_73756668 4.081 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr15_+_37660568 3.467 NM_003246
THBS1
thrombospondin 1
chr4_+_72271218 3.167 NM_001098484
NM_001134742
SLC4A4

solute carrier family 4, sodium bicarbonate cotransporter, member 4

chr3_+_64645819 2.893 LOC100507098
hypothetical LOC100507098
chr9_-_112840064 2.441 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr21_-_27139143 2.308 ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr10_+_52421120 2.306 PRKG1
protein kinase, cGMP-dependent, type I
chr16_+_85158357 2.285 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr21_-_27139563 2.195 NM_006988
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr11_+_19691397 2.147 NM_145117
NM_182964
NAV2

neuron navigator 2

chr9_+_111850698 2.139 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr9_+_108665168 2.133 NM_021224
ZNF462
zinc finger protein 462
chr20_+_19903778 2.129 RIN2
Ras and Rab interactor 2
chr7_-_27191287 2.034 NM_005523
HOXA11
homeobox A11
chr14_+_100362236 2.005 MEG3
maternally expressed 3 (non-protein coding)
chr3_+_155321826 1.970 NM_015595
ARHGEF26
Rho guanine nucleotide exchange factor (GEF) 26
chr14_+_100362204 1.898 MEG3
maternally expressed 3 (non-protein coding)
chr16_+_54070302 1.891 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr11_+_111288686 1.845 HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chr2_-_144991386 1.705 ZEB2
zinc finger E-box binding homeobox 2
chr2_-_144991556 1.666 ZEB2
zinc finger E-box binding homeobox 2
chr5_-_121440704 1.662 NM_001178102
LOX
lysyl oxidase
chr22_-_26527469 1.622 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr11_+_111288669 1.560 NM_001541
HSPB2-C11ORF52
HSPB2
HSPB2-C11orf52 read-through transcript
heat shock 27kDa protein 2
chrX_+_90576252 1.545 NM_080832
PABPC5
poly(A) binding protein, cytoplasmic 5
chr11_-_126375864 1.538 KIRREL3
kin of IRRE like 3 (Drosophila)
chr14_+_85066265 1.535 FLRT2
fibronectin leucine rich transmembrane protein 2
chr19_-_45888259 1.528 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr4_-_140696740 1.516 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr11_+_131285747 1.512 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chr7_-_106088565 1.508 NM_175884
FLJ36031
hypothetical protein FLJ36031
chr17_+_58058783 1.495 MRC2
mannose receptor, C type 2
chr3_-_71196696 1.489 FOXP1
forkhead box P1
chr1_-_21478571 1.487 NM_001113347
ECE1
endothelin converting enzyme 1
chr7_-_27180398 1.482 NM_018951
HOXA10
homeobox A10
chr10_-_62373828 1.479 NM_014836
RHOBTB1
Rho-related BTB domain containing 1
chr5_-_92982927 1.474


chr5_+_175725050 1.471 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr7_-_150576634 1.443 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr2_+_159533329 1.418 NM_001145909
NM_033394
TANC1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr13_-_73605914 1.383 NM_007249
KLF12
Kruppel-like factor 12
chr1_+_168899936 1.378 NM_006902
NM_022716
PRRX1

paired related homeobox 1

chr22_+_35777561 1.360 NM_024681
KCTD17
potassium channel tetramerisation domain containing 17
chr6_+_45498354 1.341 RUNX2
runt-related transcription factor 2
chr15_-_27901828 1.339 NM_003257
NM_175610
TJP1

tight junction protein 1 (zona occludens 1)

chr3_+_189353502 1.335 LPP
LIM domain containing preferred translocation partner in lipoma
chr11_-_126375895 1.334 NM_001161707
NM_032531
KIRREL3

kin of IRRE like 3 (Drosophila)

chr19_+_627346 1.326 NM_005860
FSTL3
follistatin-like 3 (secreted glycoprotein)
chr3_-_55490401 1.316 WNT5A
wingless-type MMTV integration site family, member 5A
chr21_+_41461962 1.309 BACE2
beta-site APP-cleaving enzyme 2
chr8_-_17599438 1.297 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr11_-_11986704 1.292 NM_001018057
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr7_+_44110527 1.290 AEBP1
AE binding protein 1
chr11_+_117983515 1.286 NM_001144758
NM_001144759
PHLDB1

pleckstrin homology-like domain, family B, member 1

chr6_+_45498262 1.278 RUNX2
runt-related transcription factor 2
chr1_-_212791188 1.266 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr3_+_112273352 1.252 PVRL3
poliovirus receptor-related 3
chr12_+_6179736 1.235 NM_001769
CD9
CD9 molecule
chr7_-_112513379 1.230 NM_001146266
NM_001146267
GPR85

G protein-coupled receptor 85

chr3_+_171619346 1.228 NM_005602
CLDN11
claudin 11
chr5_+_71438796 1.208 NM_005909
MAP1B
microtubule-associated protein 1B
chr7_-_150576660 1.198 NM_001003801
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr16_-_31390926 1.196


chr9_+_111850770 1.190 AKAP2
A kinase (PRKA) anchor protein 2
chr21_-_26867138 1.186 NM_052954
CYYR1
cysteine/tyrosine-rich 1
chr2_+_235525355 1.180 NM_014521
SH3BP4
SH3-domain binding protein 4
chr8_-_145097031 1.174 NM_201380
PLEC
plectin
chr3_+_112273464 1.162 NM_015480
PVRL3
poliovirus receptor-related 3
chr20_+_61622985 1.160 PPDPF
pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)
chr10_+_72102563 1.151 NM_080722
NM_139155
ADAMTS14

ADAM metallopeptidase with thrombospondin type 1 motif, 14

chr12_+_5411534 1.148 NM_001102654
NTF3
neurotrophin 3
chr9_+_112470871 1.141 NM_001166280
NM_001166281
NM_005592
MUSK


muscle, skeletal, receptor tyrosine kinase


chr7_+_114350144 1.138 MDFIC
MyoD family inhibitor domain containing
chr12_-_47869134 1.131 TUBA1A
tubulin, alpha 1a
chr11_-_110917632 1.129


chr21_-_35181308 1.116 RUNX1
runt-related transcription factor 1
chr7_+_27191534 1.109 HOXA11-AS1
HOXA11 antisense RNA 1 (non-protein coding)
chr5_-_83715947 1.107 EDIL3
EGF-like repeats and discoidin I-like domains 3
chr15_-_27901628 1.099 TJP1
tight junction protein 1 (zona occludens 1)
chr2_+_219991342 1.098 NM_001927
DES
desmin
chr7_+_27190688 1.085


chr12_-_47869067 1.083 NM_006009
TUBA1A
tubulin, alpha 1a
chr1_+_201862845 1.077 ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr10_-_90702490 1.070 NM_001613
ACTA2
actin, alpha 2, smooth muscle, aorta
chr7_+_44110470 1.064 NM_001129
AEBP1
AE binding protein 1
chrX_+_51653348 1.063 NM_001005333
NM_006986
MAGED1

melanoma antigen family D, 1

chr19_+_16296734 1.062 KLF2
Kruppel-like factor 2 (lung)
chr9_-_112840801 1.052 LPAR1
lysophosphatidic acid receptor 1
chr21_-_35181278 1.047 RUNX1
runt-related transcription factor 1
chr7_+_116099648 1.041 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr21_-_35181094 1.039


chr11_-_11987115 1.037 DKK3
dickkopf homolog 3 (Xenopus laevis)
chrX_+_101792949 1.036 NM_001099410
NM_001099411
NM_014710
NM_001184727
GPRASP1



G protein-coupled receptor associated sorting protein 1



chrX_+_149282097 1.035 NM_001177465
MAMLD1
mastermind-like domain containing 1
chr19_+_16296632 1.031 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chr16_+_31390567 1.027 NM_001042454
NM_001164719
TGFB1I1

transforming growth factor beta 1 induced transcript 1

chr1_-_39877883 1.024 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr12_+_95112385 1.020 ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr1_+_182622987 1.017 C1orf21
chromosome 1 open reading frame 21
chr1_-_39877928 1.015 NM_014571
HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr11_-_122571046 1.012 CLMP
CXADR-like membrane protein
chr1_-_86634511 1.006 NM_001007022
NM_001184765
NM_001184766
NM_020729
ODF2L



outer dense fiber of sperm tails 2-like



chr12_+_52653176 1.006 NM_014212
HOXC11
homeobox C11
chr12_-_94466701 1.001 NM_001042403
USP44
ubiquitin specific peptidase 44
chr13_+_30378311 0.990 NM_032849
C13orf33
chromosome 13 open reading frame 33
chr12_-_50871953 0.990 NM_001081492
NM_182507
KRT80

keratin 80

chr7_-_27190882 0.984 HOXA11
homeobox A11
chr4_+_159311353 0.977 LOC285505
hypothetical protein LOC285505
chr6_+_142664490 0.974 NM_001032394
NM_001032395
NM_020455
NM_198569
GPR126



G protein-coupled receptor 126



chr3_-_107070400 0.974 NM_170662
CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr4_+_15089931 0.964 CC2D2A
coiled-coil and C2 domain containing 2A
chr7_-_150576957 0.959 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr1_+_201862552 0.953 ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr4_-_149582948 0.951 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr9_+_34980266 0.950 NM_001135005
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr6_+_17389752 0.946 NM_001143942
RBM24
RNA binding motif protein 24
chr6_+_142665057 0.945 GPR126
G protein-coupled receptor 126
chr5_+_52812165 0.939 FST
follistatin
chr2_-_175255717 0.936 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chrX_-_114374860 0.924 NM_020871
LRCH2
leucine-rich repeats and calponin homology (CH) domain containing 2
chr12_+_8741746 0.915 NM_020734
RIMKLB
ribosomal modification protein rimK-like family member B
chr19_-_51856129 0.913 NM_145056
DACT3
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr2_-_175578156 0.913 NM_001025201
NM_001822
CHN1

chimerin (chimaerin) 1

chr13_-_109236897 0.904 NM_003749
IRS2
insulin receptor substrate 2
chr7_-_27120015 0.898 HOXA3
homeobox A3
chrX_+_133993984 0.887 NM_001078171
FAM127A
family with sequence similarity 127, member A
chr10_+_52420936 0.885 NM_001098512
PRKG1
protein kinase, cGMP-dependent, type I
chr6_-_85529884 0.883 TBX18
T-box 18
chr11_-_27697768 0.880 NM_001143807
BDNF
brain-derived neurotrophic factor
chr1_+_199519202 0.876 NM_000299
NM_001005337
PKP1

plakophilin 1 (ectodermal dysplasia/skin fragility syndrome)

chr5_-_156935283 0.876


chr5_+_140835788 0.874 PCDHGC3
protocadherin gamma subfamily C, 3
chr1_+_181259317 0.866


chr4_-_149582754 0.864 NR3C2
nuclear receptor subfamily 3, group C, member 2
chr17_+_52026058 0.863 NM_005450
NOG
noggin
chrX_-_48818585 0.862 NM_007213
PRAF2
PRA1 domain family, member 2
chr1_+_9275542 0.862 SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chrX_+_101887562 0.861 NM_001142529
NM_001142530
BHLHB9

basic helix-loop-helix domain containing, class B, 9

chr12_-_48902692 0.859 NM_001113547
LIMA1
LIM domain and actin binding 1
chr12_-_21985433 0.859 ABCC9
ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr4_+_123967389 0.856 FGF2
fibroblast growth factor 2 (basic)
chr9_+_101623957 0.856 NM_006981
NM_173199
NR4A3

nuclear receptor subfamily 4, group A, member 3

chr5_+_131621276 0.852 PDLIM4
PDZ and LIM domain 4
chr7_+_79602023 0.847 NM_002069
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr17_+_56832492 0.841 TBX2
T-box 2
chr9_-_122516399 0.838 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr7_-_27102049 0.838 NM_005522
NM_153620
HOXA1

homeobox A1

chr8_-_134653194 0.836 NM_003033
NM_173344
ST3GAL1

ST3 beta-galactoside alpha-2,3-sialyltransferase 1

chr17_+_56884560 0.834 TBX4
T-box 4
chr7_-_92301147 0.830 NM_001259
CDK6
cyclin-dependent kinase 6
chr14_+_105012106 0.828 NM_001312
CRIP2
cysteine-rich protein 2
chrX_-_134013644 0.826 NM_001078172
NM_001134321
FAM127B

family with sequence similarity 127, member B

chr13_+_75108450 0.825 LMO7
LIM domain 7
chr19_-_54557450 0.825 NM_003598
TEAD2
TEA domain family member 2
chrX_-_133984157 0.824 NM_001078173
FAM127C
family with sequence similarity 127, member C
chr13_+_41520888 0.807 NM_152910
NM_178009
DGKH

diacylglycerol kinase, eta

chr1_+_9275518 0.806 NM_025106
SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr1_+_17817397 0.806 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr11_-_44928803 0.804 NM_001076787
NM_006034
TP53I11

tumor protein p53 inducible protein 11

chr12_+_54400417 0.804 NM_002905
RDH5
retinol dehydrogenase 5 (11-cis/9-cis)
chr5_+_131621230 0.803 NM_001131027
NM_003687
PDLIM4

PDZ and LIM domain 4

chr11_-_11987198 0.802 NM_015881
DKK3
dickkopf homolog 3 (Xenopus laevis)
chr10_+_75343352 0.801 PLAU
plasminogen activator, urokinase
chr2_-_133144094 0.798 LYPD1
LY6/PLAUR domain containing 1
chr5_+_140835727 0.797 NM_002588
NM_032402
NM_032403
PCDHGC3


protocadherin gamma subfamily C, 3


chr3_-_113841200 0.794 CCDC80
coiled-coil domain containing 80
chr19_+_10597167 0.793 NM_020428
SLC44A2
solute carrier family 44, member 2
chr17_-_72045218 0.791 NM_134268
CYGB
cytoglobin
chr17_+_35751796 0.788 NM_001024809
RARA
retinoic acid receptor, alpha
chr12_+_95112131 0.788 NM_005230
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr2_+_202607554 0.786 NM_003507
FZD7
frizzled homolog 7 (Drosophila)
chr1_-_204048758 0.785 NM_173854
SLC41A1
solute carrier family 41, member 1
chr11_-_66898223 0.782 NM_001166212
CLCF1
cardiotrophin-like cytokine factor 1
chrX_+_101853912 0.782 NM_001004051
NM_001184874
NM_001184875
NM_001184876
NM_138437
GPRASP2




G protein-coupled receptor associated sorting protein 2




chr6_+_1335067 0.780 NM_001452
FOXF2
forkhead box F2
chr6_+_133604181 0.779 NM_004100
NM_172103
NM_172105
EYA4


eyes absent homolog 4 (Drosophila)


chr4_+_123967265 0.775 NM_002006
FGF2
fibroblast growth factor 2 (basic)
chr6_-_112682401 0.771 LAMA4
laminin, alpha 4
chr17_-_15185623 0.768 NM_031898
TEKT3
tektin 3
chr5_+_131621287 0.764 PDLIM4
PDZ and LIM domain 4
chr1_-_93919789 0.764 NM_003567
BCAR3
breast cancer anti-estrogen resistance 3
chr2_-_9061193 0.763 NM_138799
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr3_-_180652024 0.762 NM_021629
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr19_-_60573552 0.758 NM_000641
IL11
interleukin 11
chr8_-_13035102 0.756 NM_006094
DLC1
deleted in liver cancer 1
chr14_+_104218487 0.754


chr1_-_29321599 0.753 NM_001171868
TMEM200B
transmembrane protein 200B
chr19_-_13910167 0.751 NM_024825
PODNL1
podocan-like 1
chr1_+_155130146 0.750 NM_001080471
PEAR1
platelet endothelial aggregation receptor 1
chr1_+_234372454 0.730 NM_003272
GPR137B
G protein-coupled receptor 137B
chr6_-_112682459 0.730 NM_001105206
NM_001105207
NM_001105208
NM_001105209
NM_002290
LAMA4




laminin, alpha 4




chr11_-_61415429 0.728 NM_021727
FADS3
fatty acid desaturase 3
chr3_-_180651874 0.725 GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr8_-_119703297 0.724 SAMD12
sterile alpha motif domain containing 12
chr19_-_13808101 0.724 LOC284454
hypothetical LOC284454
chr5_+_52812236 0.721 NM_006350
NM_013409
FST

follistatin

chr8_+_70541631 0.721 SULF1
sulfatase 1
chr12_+_12935619 0.720 GPRC5A
G protein-coupled receptor, family C, group 5, member A

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.23 3.97e-12 GO:0050794 regulation of cellular process
1.20 9.02e-10 GO:0050789 regulation of biological process
1.18 1.68e-09 GO:0065007 biological regulation
1.33 4.55e-08 GO:0048856 anatomical structure development
1.35 9.98e-08 GO:0048731 system development
1.29 1.96e-07 GO:0032502 developmental process
1.30 5.66e-07 GO:0007275 multicellular organismal development
1.46 6.32e-07 GO:0023051 regulation of signaling
1.48 1.12e-06 GO:0007399 nervous system development
1.39 2.03e-06 GO:0048869 cellular developmental process
1.48 2.36e-06 GO:0009966 regulation of signal transduction
1.39 3.19e-06 GO:0030154 cell differentiation
1.46 5.22e-06 GO:0009653 anatomical structure morphogenesis
1.34 7.11e-06 GO:0048522 positive regulation of cellular process
1.10 1.93e-05 GO:0009987 cellular process
1.31 2.58e-05 GO:0048518 positive regulation of biological process
1.25 4.48e-05 GO:0023052 signaling
1.54 5.02e-05 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.00 5.42e-05 GO:0001501 skeletal system development
1.34 9.01e-05 GO:0048523 negative regulation of cellular process
1.26 1.10e-04 GO:0016043 cellular component organization
1.25 1.46e-04 GO:0031323 regulation of cellular metabolic process
1.56 2.94e-04 GO:0031328 positive regulation of cellular biosynthetic process
2.01 3.08e-04 GO:0061061 muscle structure development
1.53 3.23e-04 GO:0022008 neurogenesis
1.54 3.76e-04 GO:0048699 generation of neurons
1.75 4.38e-04 GO:0072358 cardiovascular system development
1.75 4.38e-04 GO:0072359 circulatory system development
1.54 4.75e-04 GO:0009891 positive regulation of biosynthetic process
1.30 5.09e-04 GO:0048519 negative regulation of biological process
1.34 8.67e-04 GO:0048583 regulation of response to stimulus
1.94 1.09e-03 GO:0001944 vasculature development
1.24 1.16e-03 GO:0007165 signal transduction
1.23 1.23e-03 GO:0071840 cellular component organization or biogenesis
1.24 1.34e-03 GO:0060255 regulation of macromolecule metabolic process
1.21 1.80e-03 GO:0019222 regulation of metabolic process
1.22 2.01e-03 GO:0080090 regulation of primary metabolic process
1.47 2.06e-03 GO:0032879 regulation of localization
1.53 2.21e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.45 2.53e-03 GO:0010646 regulation of cell communication
1.54 2.55e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.53 3.76e-03 GO:2000026 regulation of multicellular organismal development
1.53 3.76e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.85 4.37e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.27 4.59e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.34 5.12e-03 GO:0042692 muscle cell differentiation
1.55 5.85e-03 GO:0045595 regulation of cell differentiation
1.54 5.90e-03 GO:0030182 neuron differentiation
1.56 6.19e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.46 7.39e-03 GO:0050793 regulation of developmental process
1.46 7.81e-03 GO:0048468 cell development
1.41 7.98e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.25 8.73e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.40 8.77e-03 GO:0031325 positive regulation of cellular metabolic process
1.25 8.83e-03 GO:0071842 cellular component organization at cellular level
1.38 1.09e-02 GO:0009893 positive regulation of metabolic process
1.25 1.19e-02 GO:0031326 regulation of cellular biosynthetic process
1.80 1.27e-02 GO:0060284 regulation of cell development
1.46 1.55e-02 GO:0006351 transcription, DNA-dependent
1.54 1.58e-02 GO:0030030 cell projection organization
1.24 1.83e-02 GO:0009889 regulation of biosynthetic process
1.25 1.88e-02 GO:0010556 regulation of macromolecule biosynthetic process
2.15 2.10e-02 GO:0043062 extracellular structure organization
1.52 2.16e-02 GO:0010628 positive regulation of gene expression
1.86 2.28e-02 GO:0030334 regulation of cell migration
1.52 2.33e-02 GO:0051254 positive regulation of RNA metabolic process
1.23 2.33e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.84 2.49e-02 GO:0001568 blood vessel development
1.59 2.63e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.80 2.80e-02 GO:0051270 regulation of cellular component movement
2.15 2.81e-02 GO:0034330 cell junction organization
1.84 3.29e-02 GO:2000145 regulation of cell motility
1.63 3.45e-02 GO:0051094 positive regulation of developmental process
2.59 4.00e-02 GO:0030336 negative regulation of cell migration
2.59 4.00e-02 GO:2000146 negative regulation of cell motility
1.24 4.18e-02 GO:0010468 regulation of gene expression
1.52 4.27e-02 GO:0045893 positive regulation of transcription, DNA-dependent
1.91 4.57e-02 GO:0048514 blood vessel morphogenesis
2.18 4.84e-02 GO:0034329 cell junction assembly
7.42 4.85e-02 GO:0042693 muscle cell fate commitment

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 4.80e-07 GO:0005622 intracellular
2.31 3.61e-05 GO:0070161 anchoring junction
2.38 3.89e-05 GO:0005912 adherens junction
1.09 4.20e-05 GO:0044424 intracellular part
1.61 2.09e-04 GO:0030054 cell junction
2.54 7.49e-04 GO:0005925 focal adhesion
1.48 1.85e-03 GO:0031410 cytoplasmic vesicle
2.41 2.23e-03 GO:0005924 cell-substrate adherens junction
1.49 2.97e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.10 3.47e-03 GO:0005737 cytoplasm
2.32 5.01e-03 GO:0030055 cell-substrate junction
1.45 5.76e-03 GO:0031982 vesicle
1.46 7.25e-03 GO:0031988 membrane-bounded vesicle
1.31 7.34e-03 GO:0005856 cytoskeleton
1.61 1.53e-02 GO:0045202 synapse
1.24 1.62e-02 GO:0044459 plasma membrane part
1.08 3.51e-02 GO:0043229 intracellular organelle
1.04 4.52e-02 GO:0044464 cell part
1.04 4.66e-02 GO:0005623 cell

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 1.65e-06 GO:0005515 protein binding
1.08 1.25e-04 GO:0005488 binding
1.44 9.73e-04 GO:0001071 nucleic acid binding transcription factor activity
1.44 9.73e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
1.43 1.92e-03 GO:0030528 transcription regulator activity
1.47 1.75e-02 GO:0043565 sequence-specific DNA binding
4.95 3.96e-02 GO:0005248 voltage-gated sodium channel activity