Motif ID: PPARG.p2

Z-value: 0.823


Transcription factors associated with PPARG.p2:

Gene SymbolEntrez IDGene Name
PPARG 5468 peroxisome proliferator-activated receptor gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
PPARGchr3_+_123053360.302.6e-01Click!


Activity profile for motif PPARG.p2.

activity profile for motif PPARG.p2


Sorted Z-values histogram for motif PPARG.p2

Sorted Z-values for motif PPARG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PPARG.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_18312365 1.680 NM_017712
FKBP8
PGPEP1
FK506 binding protein 8, 38kDa
pyroglutamyl-peptidase I
chr2_+_218992053 1.457 NM_007127
VIL1
villin 1
chr20_-_62081434 1.339 NM_080621
SAMD10
sterile alpha motif domain containing 10
chr10_+_114125927 1.287 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr10_+_114125955 1.112 ACSL5
acyl-CoA synthetase long-chain family member 5
chr10_+_114126004 1.097 ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_-_3806683 1.088 NM_207356
C1orf174
chromosome 1 open reading frame 174
chr19_-_55708936 1.072 NM_001114598
ASPDH
aspartate dehydrogenase domain containing
chr8_+_145692916 1.018 NM_032902
PPP1R16A
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr19_-_13074669 0.968 LYL1
lymphoblastic leukemia derived sequence 1
chr1_-_3806564 0.961 C1orf174
chromosome 1 open reading frame 174
chr19_-_60432443 0.908 NM_173804
TMEM86B
transmembrane protein 86B
chr17_-_59451662 0.847 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr8_-_145613058 0.831 NM_130849
SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr8_-_145613034 0.743 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr19_+_1442000 0.657 NM_138393
REEP6
receptor accessory protein 6
chr11_+_303852 0.604 NM_003641
IFITM1
interferon induced transmembrane protein 1 (9-27)
chr11_+_46697335 0.598 F2
coagulation factor II (thrombin)
chr21_-_10120690 0.570 NM_001187
NM_182484
NM_181704
NM_182481
NM_182482
BAGE
BAGE5
BAGE4
BAGE3
BAGE2
B melanoma antigen
B melanoma antigen family, member 5
B melanoma antigen family, member 4
B melanoma antigen family, member 3
B melanoma antigen family, member 2
chr11_+_46697312 0.559 NM_000506
F2
coagulation factor II (thrombin)
chr11_+_2880135 0.549 SLC22A18
solute carrier family 22, member 18
chr11_+_46697345 0.524 F2
coagulation factor II (thrombin)
chr19_-_4491024 0.506 NM_052972
LRG1
leucine-rich alpha-2-glycoprotein 1
chr17_-_71747867 0.478 NM_052916
RNF157
ring finger protein 157
chr11_+_66927976 0.460 NM_198517
TBC1D10C
TBC1 domain family, member 10C
chr19_-_4491078 0.452 LRG1
leucine-rich alpha-2-glycoprotein 1
chr22_-_21814208 0.430 NM_014433
RTDR1
rhabdoid tumor deletion region gene 1
chr7_-_128330615 0.428 KCP
kielin/chordin-like protein
chr22_+_21006814 0.428


chr1_-_31003181 0.427 LAPTM5
lysosomal protein transmembrane 5
chr16_+_88696172 0.424 FAM157C
family with sequence similarity 157, member C
chr11_+_2880104 0.423 SLC22A18
solute carrier family 22, member 18
chr7_-_156161130 0.419


chr6_-_31736488 0.416 NM_021184
C6orf47
chromosome 6 open reading frame 47
chr19_-_13074973 0.408 NM_005583
LYL1
lymphoblastic leukemia derived sequence 1
chr5_-_176869943 0.395 NM_001144875
NM_001144876
DOK3

docking protein 3

chr1_-_31003260 0.393 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr22_+_21042091 0.389 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr1_+_205992004 0.389 NM_002389
NM_153826
NM_172350
NM_172351
NM_172352
NM_172353
NM_172359
NM_172361
CD46







CD46 molecule, complement regulatory protein







chr1_+_45542138 0.380 LOC400752
hypothetical LOC400752
chr1_-_204455269 0.375 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr20_+_764710 0.375 NM_207121
FAM110A
family with sequence similarity 110, member A
chr19_+_54361216 0.370 TRPM4
transient receptor potential cation channel, subfamily M, member 4
chr6_-_28999388 0.357 TRIM27
tripartite motif containing 27
chr8_-_145672525 0.357 NM_003923
FOXH1
forkhead box H1
chr16_+_84204424 0.355 NM_014615
KIAA0182
KIAA0182
chr13_+_48692472 0.354 NM_001507
MLNR
motilin receptor
chr19_-_5821546 0.352 NM_002034
FUT5
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr7_+_128367961 0.348 NM_001098627
IRF5
interferon regulatory factor 5
chr19_-_54618410 0.347 NM_178449
PTH2
parathyroid hormone 2
chr11_+_384199 0.346 NM_007183
PKP3
plakophilin 3
chr14_+_23855291 0.339 LTB4R
leukotriene B4 receptor
chr1_-_150029529 0.337 NM_001083963
NM_001083964
NM_001083965
NM_006862
TDRKH



tudor and KH domain containing



chr10_-_11976704 0.337 LOC219731
hypothetical LOC219731
chr17_+_42641712 0.323 NM_002476
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr19_+_54708389 0.319 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr1_+_205992032 0.315 CD46
CD46 molecule, complement regulatory protein
chr16_-_3567354 0.314 NM_178844
NLRC3
NLR family, CARD domain containing 3
chr19_+_16860807 0.313 NM_003950
F2RL3
coagulation factor II (thrombin) receptor-like 3
chr10_-_72032519 0.308 NM_001083116
NM_005041
PRF1

perforin 1 (pore forming protein)

chr19_+_19487535 0.306 NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr14_-_74458897 0.306 NM_031464
RPS6KL1
ribosomal protein S6 kinase-like 1
chr17_+_16259573 0.304 NM_016113
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr11_-_63689780 0.302 MACROD1
MACRO domain containing 1
chr1_+_153546138 0.294 FDPS
farnesyl diphosphate synthase
chr16_-_28425632 0.282 NM_145659
IL27
interleukin 27
chr17_-_31231421 0.281 NM_002985
CCL5
chemokine (C-C motif) ligand 5
chr1_+_13903936 0.280 NM_012231
NM_015866
PRDM2

PR domain containing 2, with ZNF domain

chr15_-_38908197 0.280 NM_001130143
NM_017726
PPP1R14D

protein phosphatase 1, regulatory (inhibitor) subunit 14D

chr5_+_156628929 0.279 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr11_-_5212168 0.279 NM_000519
HBD
hemoglobin, delta
chr14_+_99601498 0.274 NM_016337
EVL
Enah/Vasp-like
chr10_-_99042419 0.272 ARHGAP19
Rho GTPase activating protein 19
chr11_+_66927955 0.271 TBC1D10C
TBC1 domain family, member 10C
chr1_+_201541241 0.267 BTG2
BTG family, member 2
chr10_-_99042348 0.264 ARHGAP19
Rho GTPase activating protein 19
chr11_+_63765106 0.260 NM_001135208
FKBP2
FK506 binding protein 2, 13kDa
chr8_+_11388918 0.259 NM_001715
BLK
B lymphoid tyrosine kinase
chr11_+_125731305 0.259 NM_006278
ST3GAL4
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr12_+_56135353 0.257 NM_031479
INHBE
inhibin, beta E
chr9_-_135140450 0.255 NM_020469
ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr10_-_99042381 0.250 NM_032900
ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 read-through transcript
Rho GTPase activating protein 19
chr11_-_8982107 0.248 NM_020645
NRIP3
nuclear receptor interacting protein 3
chr11_+_298106 0.244 NM_006435
IFITM2
interferon induced transmembrane protein 2 (1-8D)
chr22_+_21484240 0.241


chr9_-_135140425 0.239 ABO
ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
chr9_-_130006309 0.236 NM_001131015
NM_012127
CIZ1

CDKN1A interacting zinc finger protein 1

chr19_-_44060729 0.232 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr7_-_100262971 0.229 NM_004444
EPHB4
EPH receptor B4
chr19_+_7874701 0.226 MAP2K7
mitogen-activated protein kinase kinase 7
chr19_-_54636425 0.225 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr17_-_35331435 0.222 ORMDL3
ORM1-like 3 (S. cerevisiae)
chr2_-_89223666 0.219 IGKC
IGK@
immunoglobulin kappa constant
immunoglobulin kappa locus
chr4_-_176970407 0.217 GPM6A
glycoprotein M6A
chr17_-_37590910 0.215 NM_001524
HCRT
hypocretin (orexin) neuropeptide precursor
chr7_-_38341697 0.212 TRGV7
T cell receptor gamma variable 7 pseudogene
chr4_-_176970372 0.211 GPM6A
glycoprotein M6A
chr19_-_60610971 0.211 UBE2S
ubiquitin-conjugating enzyme E2S
chr12_+_6807831 0.207 NM_014262
LEPREL2
leprecan-like 2
chr19_+_7874820 0.206 MAP2K7
mitogen-activated protein kinase kinase 7
chr14_+_23700261 0.200 NM_006084
IRF9
interferon regulatory factor 9
chr19_-_5790702 0.197 NM_000150
NM_001040701
FUT6

fucosyltransferase 6 (alpha (1,3) fucosyltransferase)

chr19_-_2691009 0.195 SLC39A3
solute carrier family 39 (zinc transporter), member 3
chr11_+_384238 0.194 PKP3
plakophilin 3
chr2_+_112612429 0.189 NM_001128165
NM_153214
FBLN7

fibulin 7

chr7_-_99365178 0.186 NM_181538
GJC3
gap junction protein, gamma 3, 30.2kDa
chr9_-_135232734 0.185 SURF4
surfeit 4
chr8_+_144888275 0.184 LOC100128338
hypothetical LOC100128338
chr19_+_7874762 0.181 MAP2K7
mitogen-activated protein kinase kinase 7
chr19_-_2691001 0.181 SLC39A3
solute carrier family 39 (zinc transporter), member 3
chr9_-_135232735 0.179 SURF4
surfeit 4
chr1_+_19796044 0.179 NM_001032363
C1orf15-NBL1
C1orf151
C1ORF15-NBL1 read-through transcript
chromosome 1 open reading frame 151
chr20_-_43974092 0.177 NM_006227
NM_182676
PLTP

phospholipid transfer protein

chr7_-_20223467 0.176 NM_182762
MACC1
metastasis associated in colon cancer 1
chr17_+_22982319 0.173 LGALS9
lectin, galactoside-binding, soluble, 9
chr14_+_99601517 0.171 EVL
Enah/Vasp-like
chr7_+_98994199 0.170 ZNF655
zinc finger protein 655
chr22_+_20880159 0.169 IGLV6-57
immunoglobulin lambda variable 6-57
chr11_+_2880063 0.169 NM_002555
SLC22A18
solute carrier family 22, member 18
chr22_+_25347927 0.166 NM_001886
CRYBA4
crystallin, beta A4
chr1_+_44208236 0.165 NM_001039589
NM_001384
DPH2

DPH2 homolog (S. cerevisiae)

chr19_+_7874765 0.164 MAP2K7
mitogen-activated protein kinase kinase 7
chr12_-_110521743 0.164 NM_002973
ATXN2
ataxin 2
chr17_-_59327602 0.163 NM_001317
NM_022640
NM_022641
CSH1


CSH2
chorionic somatomammotropin hormone 1 (placental lactogen)


chorionic somatomammotropin hormone 2
chr17_+_16259636 0.158 TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr8_-_9046460 0.157 PPP1R3B
protein phosphatase 1, regulatory (inhibitor) subunit 3B
chr7_+_150390566 0.156 SLC4A2
solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
chr1_+_19796119 0.153


chr2_-_200030944 0.153 NM_001172509
SATB2
SATB homeobox 2
chr19_+_7874764 0.150 NM_145185
MAP2K7
mitogen-activated protein kinase kinase 7
chr4_-_53220073 0.149 NM_022832
USP46
ubiquitin specific peptidase 46
chr9_-_135232790 0.146 NM_033161
SURF4
surfeit 4
chr11_+_2881080 0.146 SLC22A18
solute carrier family 22, member 18
chr1_-_154665807 0.146 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr5_-_179040580 0.145 NM_001164444
CBY3
chibby homolog 3 (Drosophila)
chr2_+_112612511 0.145 FBLN7
fibulin 7
chr1_-_6448737 0.144 NM_001039664
NM_003790
NM_148965
NM_148966
NM_148967
NM_148970
TNFRSF25





tumor necrosis factor receptor superfamily, member 25





chr5_+_133870175 0.140


chr12_-_54869568 0.139 NM_001130420
NM_003075
NM_139067
SMARCC2


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2


chr9_-_135232754 0.139 SURF4
surfeit 4
chr11_+_63764988 0.139 NM_004470
FKBP2
FK506 binding protein 2, 13kDa
chr19_+_54530512 0.137 CD37
CD37 molecule
chr11_-_67528103 0.137 NM_030930
UNC93B1
unc-93 homolog B1 (C. elegans)
chrX_+_105823723 0.137 NM_024539
RNF128
ring finger protein 128
chr11_+_66499323 0.137 NM_001136485
C11orf86
chromosome 11 open reading frame 86
chr9_-_135232746 0.136 SURF4
surfeit 4
chr19_-_61396232 0.133 NM_001080456
ZSCAN5B
zinc finger and SCAN domain containing 5B
chr19_-_2690963 0.132 SLC39A3
solute carrier family 39 (zinc transporter), member 3
chr20_-_34807882 0.130 NM_022477
NM_032013
NDRG3

NDRG family member 3

chr19_-_14447163 0.129 NM_000955
PTGER1
prostaglandin E receptor 1 (subtype EP1), 42kDa
chr20_+_33593243 0.128 ERGIC3
ERGIC and golgi 3
chr4_+_2764609 0.127 SH3BP2
SH3-domain binding protein 2
chr14_-_105524207 0.126 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr5_-_141318810 0.125 NM_016580
PCDH12
protocadherin 12
chr1_-_37991160 0.124 EPHA10
EPH receptor A10
chr14_+_104117100 0.122 NM_001008404
C14orf180
chromosome 14 open reading frame 180
chr19_+_7874774 0.121 MAP2K7
mitogen-activated protein kinase kinase 7
chr15_-_88148177 0.121 ANPEP
alanyl (membrane) aminopeptidase
chr19_-_60350122 0.121 TNNT1
troponin T type 1 (skeletal, slow)
chr6_+_132901119 0.118 NM_175057
TAAR9
trace amine associated receptor 9 (gene/pseudogene)
chr1_+_26389638 0.118 NM_198137
CATSPER4
cation channel, sperm associated 4
chr2_+_27200160 0.117 NM_032604
ABHD1
abhydrolase domain containing 1
chr22_+_21559959 0.117 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr6_+_7053863 0.117 RREB1
ras responsive element binding protein 1
chr17_+_75319476 0.116 NM_178543
ENPP7
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr22_+_18388602 0.115 NM_152906
C22orf25
chromosome 22 open reading frame 25
chr22_+_20880112 0.115


chr18_+_27925815 0.114 NM_016271
RNF138
ring finger protein 138
chr17_+_22982344 0.114 LGALS9
lectin, galactoside-binding, soluble, 9
chr11_+_268569 0.113 NM_138329
NLRP6
NLR family, pyrin domain containing 6
chr18_+_27925859 0.111 RNF138
ring finger protein 138
chr7_-_128337997 0.111 NM_001135914
NM_199349
KCP

kielin/chordin-like protein

chr11_-_63749916 0.110 NM_001160393
TRPT1
tRNA phosphotransferase 1
chr22_+_18388633 0.109 C22orf25
chromosome 22 open reading frame 25
chr19_-_2691053 0.108 NM_144564
NM_213568
SLC39A3

solute carrier family 39 (zinc transporter), member 3

chr20_+_33593191 0.108 NM_015966
NM_198398
ERGIC3

ERGIC and golgi 3

chr3_+_170974745 0.107 NM_001185119
MYNN
myoneurin
chr19_+_18608827 0.107 NM_018316
KLHL26
kelch-like 26 (Drosophila)
chr7_+_142270634 0.107 EPHB6
EPH receptor B6
chr9_-_135232767 0.105 SURF4
surfeit 4
chr12_+_119391982 0.105 NM_001037494
DYNLL1
dynein, light chain, LC8-type 1
chr1_+_201541269 0.105 NM_006763
BTG2
BTG family, member 2
chr6_+_33276580 0.105 NM_001077516
NM_006979
SLC39A7

solute carrier family 39 (zinc transporter), member 7

chr11_-_1287256 0.104 TOLLIP
toll interacting protein
chr6_+_31573805 0.104 NM_005931
MICB
MHC class I polypeptide-related sequence B
chr6_+_6533932 0.103 NM_004271
LY86
lymphocyte antigen 86
chrX_+_70360184 0.103 GJB1
gap junction protein, beta 1, 32kDa
chr17_+_22982278 0.102 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr20_-_33705244 0.102 NM_003915
CPNE1
copine I
chr19_+_951295 0.102 NM_138690
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr7_-_44165398 0.100 NM_033507
NM_033508
GCK

glucokinase (hexokinase 4)

chr9_+_135232937 0.098 C9orf96
chromosome 9 open reading frame 96
chr4_+_129201952 0.098 NM_018078
NM_032239
NM_178043
LARP1B


La ribonucleoprotein domain family, member 1B


chr22_+_21011653 0.097


chr10_-_72032447 0.097 PRF1
perforin 1 (pore forming protein)
chr20_+_33593247 0.096 ERGIC3
ERGIC and golgi 3
chr19_-_60610792 0.095 UBE2S
ubiquitin-conjugating enzyme E2S
chr1_-_92144146 0.094 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr6_-_31890765 0.094 NM_005527
HSPA1L
heat shock 70kDa protein 1-like
chr12_-_121277972 0.092 NM_019887
NM_138929
DIABLO

diablo homolog (Drosophila)


Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.82 4.12e-04 GO:0044459 plasma membrane part
1.98 9.25e-03 GO:0005887 integral to plasma membrane
1.94 1.37e-02 GO:0031226 intrinsic to plasma membrane
1.35 2.22e-02 GO:0016021 integral to membrane
1.34 3.14e-02 GO:0031224 intrinsic to membrane

Nothing significant found in function category.