Motif ID: ZNF148.p2

Z-value: 1.627


Transcription factors associated with ZNF148.p2:

Gene SymbolEntrez IDGene Name
ZNF148 7707 zinc finger protein 148

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ZNF148chr3_-_1265766930.126.6e-01Click!


Activity profile for motif ZNF148.p2.

activity profile for motif ZNF148.p2


Sorted Z-values histogram for motif ZNF148.p2

Sorted Z-values for motif ZNF148.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF148.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_49916304 1.363 NM_002447
MST1R
macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
chr22_-_49317408 1.258 ODF3B
outer dense fiber of sperm tails 3B
chr17_-_1029758 1.193 NM_021962
ABR
active BCR-related gene
chr3_+_16901455 1.192 NM_001144382
PLCL2
phospholipase C-like 2
chr6_-_32929570 1.164 TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_-_32929721 1.113 NM_000593
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_+_32929902 0.987 NM_002800
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
chr3_-_129023850 0.948 NM_007283
MGLL
monoglyceride lipase
chr17_-_3407780 0.904 TRPV3
transient receptor potential cation channel, subfamily V, member 3
chr17_+_73676219 0.892 NM_004710
SYNGR2
synaptogyrin 2
chr4_-_2906256 0.846 MFSD10
major facilitator superfamily domain containing 10
chr6_-_32929390 0.832 TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr4_-_2906335 0.817 MFSD10
major facilitator superfamily domain containing 10
chr17_-_64834780 0.808 NM_172232
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr4_-_2906361 0.800 NM_001146069
MFSD10
major facilitator superfamily domain containing 10
chr17_-_3408038 0.787 NM_145068
TRPV3
transient receptor potential cation channel, subfamily V, member 3
chr19_-_4016467 0.764 ZBTB7A
zinc finger and BTB domain containing 7A
chr19_+_1358750 0.763 DAZAP1
DAZ associated protein 1
chr22_+_40800213 0.757 FAM109B
family with sequence similarity 109, member B
chr16_+_67698943 0.744 NM_005329
HAS3
hyaluronan synthase 3
chr12_-_116283380 0.742 NOS1
nitric oxide synthase 1 (neuronal)
chr1_+_154390939 0.737 SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr2_+_37425240 0.732 NM_012413
QPCT
glutaminyl-peptide cyclotransferase
chr22_+_40800193 0.731 NM_001002034
FAM109B
family with sequence similarity 109, member B
chr5_-_9599157 0.722 NM_003966
SEMA5A
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr11_-_431995 0.708 NM_001012302
ANO9
anoctamin 9
chr4_-_765586 0.698 LOC100129917
hypothetical LOC100129917
chr12_+_58276114 0.697 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr5_+_68746694 0.687 NM_001038603
MARVELD2
MARVEL domain containing 2
chr2_-_9061193 0.686 NM_138799
MBOAT2
membrane bound O-acyltransferase domain containing 2
chr4_-_2906341 0.668 MFSD10
major facilitator superfamily domain containing 10
chr11_-_431956 0.667 ANO9
anoctamin 9
chr2_-_20288108 0.663 NM_002997
SDC1
syndecan 1
chr10_+_104145421 0.662 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr4_-_2905649 0.655 NM_001120
MFSD10
major facilitator superfamily domain containing 10
chr12_+_110328126 0.641 NM_005475
SH2B3
SH2B adaptor protein 3
chr19_-_59666705 0.632 NM_198988
LENG9
leukocyte receptor cluster (LRC) member 9
chr10_-_90332927 0.619 NM_001031709
NM_018363
RNLS

renalase, FAD-dependent amine oxidase

chr3_+_198214173 0.613 LOC100507057
MFI2
hypothetical LOC100507057
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr11_+_2355099 0.612 CD81
CD81 molecule
chr22_+_48698337 0.594 CRELD2
cysteine-rich with EGF-like domains 2
chr18_-_26876622 0.581 NM_001941
NM_024423
DSC3

desmocollin 3

chr4_-_35922288 0.571 NM_015230
ARAP2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr17_-_1335763 0.564 NM_001080950
MYO1C
myosin IC
chr16_-_1404635 0.556 NM_001037125
NM_001193388
UNKL

unkempt homolog (Drosophila)-like

chr8_+_86563382 0.551 NM_000067
CA2
carbonic anhydrase II
chr22_-_28992787 0.546 NM_020530
OSM
oncostatin M
chr10_+_120957084 0.543 NM_005308
GRK5
G protein-coupled receptor kinase 5
chr22_-_37598160 0.543 CBX6
chromobox homolog 6
chr18_+_40513889 0.543 NM_001130110
SETBP1
SET binding protein 1
chr4_+_2906403 0.534 C4orf10
chromosome 4 open reading frame 10
chr15_+_29406335 0.530 NM_015995
KLF13
Kruppel-like factor 13
chr15_-_43209348 0.529 NM_144565
DUOXA1
dual oxidase maturation factor 1
chr5_+_156819782 0.529 NIPAL4
NIPA-like domain containing 4
chr8_+_145662510 0.526 NM_145754
KIFC2
kinesin family member C2
chrX_-_48212683 0.525 SLC38A5
solute carrier family 38, member 5
chr10_+_88720477 0.521 NM_133447
AGAP11
ankyrin repeat and GTPase domain Arf GTPase activating protein 11
chr17_-_59561207 0.518 NM_001433
ERN1
endoplasmic reticulum to nucleus signaling 1
chr9_-_35608300 0.518 NM_001782
CD72
CD72 molecule
chr22_+_44828338 0.514


chr5_+_154115222 0.512 LARP1
La ribonucleoprotein domain family, member 1
chr9_-_122731263 0.499 NM_001190945
TRAF1
TNF receptor-associated factor 1
chr20_+_36867708 0.497 NM_001172735
NM_015568
PPP1R16B

protein phosphatase 1, regulatory (inhibitor) subunit 16B

chr19_+_3129735 0.496 NM_003775
S1PR4
sphingosine-1-phosphate receptor 4
chrX_+_21302317 0.493 NM_001168647
NM_001168648
NM_001168649
NM_014927
CNKSR2



connector enhancer of kinase suppressor of Ras 2



chr7_-_3049872 0.484 NM_032415
CARD11
caspase recruitment domain family, member 11
chr10_+_112247614 0.482 NM_004419
DUSP5
dual specificity phosphatase 5
chr16_+_639278 0.480 NM_145294
WDR90
WD repeat domain 90
chr1_+_891739 0.479 NM_001160184
NM_032129
PLEKHN1

pleckstrin homology domain containing, family N member 1

chr7_-_100068612 0.477 TFR2
transferrin receptor 2
chr18_+_11679135 0.477 NM_182978
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr1_-_159306037 0.476 ARHGAP30
Rho GTPase activating protein 30
chr1_-_6468600 0.475 NM_001042665
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr10_-_103864651 0.474 NM_003893
LDB1
LIM domain binding 1
chr17_+_6858779 0.469 NM_001142798
NM_001142799
NM_174893
C17orf49


chromosome 17 open reading frame 49


chr4_-_2905448 0.466 MFSD10
major facilitator superfamily domain containing 10
chr2_-_20288647 0.463 NM_001006946
SDC1
syndecan 1
chr16_+_68233 0.463 MPG
N-methylpurine-DNA glycosylase
chr22_-_44828636 0.460 NM_018280
C22orf26
chromosome 22 open reading frame 26
chrX_+_129133234 0.458 NM_004794
RAB33A
RAB33A, member RAS oncogene family
chr17_-_58877276 0.457 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr10_-_30065760 0.456 SVIL
supervillin
chr22_-_30016707 0.454 PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr9_-_21984414 0.450 NM_058195
CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr21_+_42512271 0.449 NM_004915
NM_016818
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr1_-_9111674 0.443 NM_024980
GPR157
G protein-coupled receptor 157
chr10_+_47875229 0.442 NM_001040084
NM_001098845
ANXA8L2
ANXA8
ANXA8L1
annexin A8-like 2
annexin A8
annexin A8-like 1
chr3_-_109292444 0.434 NM_001777
NM_198793
CD47

CD47 molecule

chr19_+_46390980 0.434 CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr19_+_46390916 0.433 NM_030622
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr7_-_143523582 0.432 NM_001003702
ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr22_+_48698282 0.428 NM_001135101
NM_024324
CRELD2

cysteine-rich with EGF-like domains 2

chr1_-_1041598 0.428 NM_017891
C1orf159
chromosome 1 open reading frame 159
chr17_+_7180571 0.426 NM_014716
ACAP1
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr14_+_105024576 0.422 CRIP1
cysteine-rich protein 1 (intestinal)
chr1_+_152014391 0.420 NM_024330
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr22_-_43986896 0.419 KIAA0930
KIAA0930
chr8_+_145137354 0.415 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr5_+_76150637 0.414 F2RL1
coagulation factor II (thrombin) receptor-like 1
chr6_+_144513324 0.414 NM_003764
STX11
syntaxin 11
chr16_+_82959626 0.413 NM_014861
ATP2C2
ATPase, Ca++ transporting, type 2C, member 2
chr2_+_219453487 0.413 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr1_-_159306273 0.413 ARHGAP30
Rho GTPase activating protein 30
chr1_-_159306210 0.413 ARHGAP30
Rho GTPase activating protein 30
chr21_+_34963557 0.411 NM_053277
CLIC6
chloride intracellular channel 6
chr17_-_45562112 0.410 NM_174920
SAMD14
sterile alpha motif domain containing 14
chr5_+_156819604 0.409 NM_001099287
NM_001172292
NIPAL4

NIPA-like domain containing 4

chr19_-_11311254 0.409 NM_004283
RAB3D
RAB3D, member RAS oncogene family
chr11_+_527521 0.408 NM_198075
LRRC56
leucine rich repeat containing 56
chr21_-_44485127 0.407 NM_015259
ICOSLG
inducible T-cell co-stimulator ligand
chr7_+_128365226 0.407 NM_001098629
NM_001098630
IRF5

interferon regulatory factor 5

chr19_+_2047792 0.407 NM_001031735
NM_001039846
IZUMO4

IZUMO family member 4

chr1_+_231530136 0.406 NM_032435
KIAA1804
mixed lineage kinase 4
chr2_-_166358951 0.405 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr22_-_43987010 0.404 NM_015264
KIAA0930
KIAA0930
chr8_-_70907957 0.403 NM_001146009
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr3_-_198767202 0.402 NM_004051
NM_203314
BDH1

3-hydroxybutyrate dehydrogenase, type 1

chr3_-_129024665 0.401 NM_001003794
MGLL
monoglyceride lipase
chr17_-_1336073 0.400 MYO1C
myosin IC
chr11_-_1549719 0.397 NM_004420
DUSP8
dual specificity phosphatase 8
chr2_-_166359016 0.397 NM_004482
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr1_-_159306369 0.397 NM_001025598
NM_181720
ARHGAP30

Rho GTPase activating protein 30

chr1_+_13899272 0.394 NM_001135610
PRDM2
PR domain containing 2, with ZNF domain
chr14_-_105245959 0.391 IGHA1
immunoglobulin heavy constant alpha 1
chr21_-_46473143 0.389 NM_001001438
NM_001145436
NM_001145437
NM_002340
LSS



lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)



chr7_+_143683365 0.388 NM_005435
ARHGEF5
Rho guanine nucleotide exchange factor (GEF) 5
chr4_-_7991992 0.385 NM_001134647
NM_198595
AFAP1

actin filament associated protein 1

chr19_+_55614006 0.384 NM_003121
SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr1_+_34997928 0.382 NM_153212
GJB4
gap junction protein, beta 4, 30.3kDa
chr16_+_80370426 0.380 NM_002661
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr7_+_101245812 0.380 NM_001913
NM_181500
CUX1

cut-like homeobox 1

chr12_-_120715937 0.380 NM_019034
RHOF
ras homolog gene family, member F (in filopodia)
chr16_+_68223 0.379 MPG
N-methylpurine-DNA glycosylase
chr9_+_139292094 0.379 NM_017723
C9orf167
chromosome 9 open reading frame 167
chr1_-_21489475 0.379 NM_001397
ECE1
endothelin converting enzyme 1
chr21_-_44485269 0.378 ICOSLG
inducible T-cell co-stimulator ligand
chr1_-_159306327 0.377 ARHGAP30
Rho GTPase activating protein 30
chr22_+_24290885 0.377 ADRBK2
adrenergic, beta, receptor kinase 2
chr17_-_59131194 0.376 LIMD2
LIM domain containing 2
chr7_+_98314020 0.374 NM_003496
TRRAP
transformation/transcription domain-associated protein
chr16_+_68168 0.374 NM_001015052
NM_002434
MPG

N-methylpurine-DNA glycosylase

chr20_-_57015547 0.367 CTSZ
cathepsin Z
chr14_+_60858151 0.365 NM_006255
PRKCH
protein kinase C, eta
chr20_-_61639104 0.362 NM_005975
PTK6
PTK6 protein tyrosine kinase 6
chr20_-_3696344 0.362 NM_001039140
C20orf27
chromosome 20 open reading frame 27
chr4_+_142777172 0.361 NM_000585
NM_172174
IL15

interleukin 15

chr2_-_127694123 0.359 CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr9_-_21984379 0.358 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr22_+_28609064 0.357 NM_021090
NM_153050
NM_153051
MTMR3


myotubularin related protein 3


chr19_+_1358664 0.356 DAZAP1
DAZ associated protein 1
chr2_-_166358792 0.354 GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr9_-_21984329 0.353 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr20_-_4752067 0.352 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr19_-_47261761 0.352 NM_002088
GRIK5
glutamate receptor, ionotropic, kainate 5
chr22_+_42751487 0.351 NM_013327
PARVB
parvin, beta
chr15_+_62921134 0.351 NM_001195059
NM_025201
PLEKHO2

pleckstrin homology domain containing, family O member 2

chr1_+_15608974 0.350 NM_024329
EFHD2
EF-hand domain family, member D2
chr8_+_144171275 0.350 NM_001127213
NM_002346
LY6E

lymphocyte antigen 6 complex, locus E

chr6_-_30762385 0.350 KIAA1949
KIAA1949
chrX_+_56275510 0.350 NM_007250
NM_001159296
KLF8

Kruppel-like factor 8

chr10_-_103864579 0.348 LDB1
LIM domain binding 1
chr10_+_134201262 0.348 NM_005539
INPP5A
inositol polyphosphate-5-phosphatase, 40kDa
chr22_+_24290738 0.347 NM_005160
ADRBK2
adrenergic, beta, receptor kinase 2
chr22_-_49315265 0.347 TYMP
thymidine phosphorylase
chr3_-_159872960 0.346 NM_020169
LXN
latexin
chr2_+_238265791 0.346 LRRFIP1
leucine rich repeat (in FLII) interacting protein 1
chr22_+_23153529 0.345 NM_000675
ADORA2A
adenosine A2a receptor
chr8_-_144731498 0.345 NAPRT1
nicotinate phosphoribosyltransferase domain containing 1
chr11_-_119514011 0.344 TRIM29
tripartite motif containing 29
chr17_-_77478835 0.344 NM_002359
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr10_-_103869923 0.343 NM_001113407
LDB1
LIM domain binding 1
chr5_+_154115046 0.342 LARP1
La ribonucleoprotein domain family, member 1
chr18_-_20231709 0.341 OSBPL1A
oxysterol binding protein-like 1A
chr22_+_29420792 0.341 NM_030758
OSBP2
oxysterol binding protein 2
chr1_+_15609009 0.340 EFHD2
EF-hand domain family, member D2
chr10_-_134940315 0.339 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr3_+_185538998 0.339 FAM131A
family with sequence similarity 131, member A
chr9_-_139316523 0.338 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr18_+_18969724 0.337 NM_001100619
CABLES1
Cdk5 and Abl enzyme substrate 1
chr19_-_47451119 0.336 NM_006494
ERF
Ets2 repressor factor
chr2_+_84986510 0.334 TMSB10
thymosin beta 10
chr14_+_104785936 0.333 BTBD6
BTB (POZ) domain containing 6
chr17_-_75735354 0.333 NM_014740
EIF4A3
eukaryotic translation initiation factor 4A3
chr13_-_110365336 0.331 ANKRD10
ankyrin repeat domain 10
chr22_-_37598176 0.330 NM_014292
CBX6
chromobox homolog 6
chr22_-_26645150 0.329 PITPNB
phosphatidylinositol transfer protein, beta
chr11_-_525532 0.329 NM_001130442
NM_005343
NM_176795
HRAS


v-Ha-ras Harvey rat sarcoma viral oncogene homolog


chr4_+_2790338 0.329 NM_003023
SH3BP2
SH3-domain binding protein 2
chr8_-_145640579 0.327 TONSL
tonsoku-like, DNA repair protein
chr19_+_44590345 0.326 ZFP36
zinc finger protein 36, C3H type, homolog (mouse)
chr7_+_75977680 0.326 NM_030570
NM_182684
UPK3B

uroplakin 3B

chr14_-_76564374 0.326 IRF2BPL
interferon regulatory factor 2 binding protein-like
chr7_-_143622233 0.326 ARHGEF35
Rho guanine nucleotide exchange factor (GEF) 35
chr12_+_622374 0.325 LOC100049716
hypothetical LOC100049716
chr1_-_94779727 0.325 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr22_-_37598115 0.324 CBX6
chromobox homolog 6
chr19_+_13924287 0.324 DCAF15
DDB1 and CUL4 associated factor 15
chr17_+_72789086 0.322 NM_001113491
SEPT9
septin 9
chr14_-_102593384 0.321 NM_006035
CDC42BPB
CDC42 binding protein kinase beta (DMPK-like)
chr15_+_73281286 0.321 C15orf39
chromosome 15 open reading frame 39

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.18 4.47e-18 GO:0050794 regulation of cellular process
1.16 3.56e-17 GO:0065007 biological regulation
1.17 1.11e-16 GO:0050789 regulation of biological process
1.27 5.64e-14 GO:0007165 signal transduction
1.24 1.63e-12 GO:0023052 signaling
1.20 1.06e-09 GO:0051716 cellular response to stimulus
1.32 1.86e-09 GO:0048583 regulation of response to stimulus
1.33 2.31e-09 GO:0006464 protein modification process
1.38 8.14e-09 GO:0035556 intracellular signal transduction
1.37 8.25e-09 GO:0009966 regulation of signal transduction
1.34 8.78e-09 GO:0023051 regulation of signaling
1.30 4.37e-08 GO:0043412 macromolecule modification
1.23 1.15e-06 GO:0048518 positive regulation of biological process
1.24 1.81e-06 GO:0048522 positive regulation of cellular process
1.19 2.38e-06 GO:0031323 regulation of cellular metabolic process
1.07 2.39e-06 GO:0009987 cellular process
1.19 5.09e-06 GO:0080090 regulation of primary metabolic process
1.17 2.16e-05 GO:0019222 regulation of metabolic process
1.36 2.70e-05 GO:0006793 phosphorus metabolic process
1.36 2.70e-05 GO:0006796 phosphate metabolic process
1.23 5.41e-05 GO:0051252 regulation of RNA metabolic process
1.22 5.52e-05 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.18 6.16e-05 GO:0060255 regulation of macromolecule metabolic process
1.21 7.60e-05 GO:0010468 regulation of gene expression
1.21 9.65e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.22 1.28e-04 GO:0006355 regulation of transcription, DNA-dependent
1.20 1.36e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.20 1.36e-04 GO:0031326 regulation of cellular biosynthetic process
1.39 1.56e-04 GO:0048584 positive regulation of response to stimulus
1.19 2.68e-04 GO:0009889 regulation of biosynthetic process
1.19 3.42e-04 GO:0051171 regulation of nitrogen compound metabolic process
1.24 3.62e-04 GO:0007166 cell surface receptor linked signaling pathway
1.21 3.74e-04 GO:0048519 negative regulation of biological process
1.54 5.90e-04 GO:0010627 regulation of intracellular protein kinase cascade
1.20 5.95e-04 GO:0044267 cellular protein metabolic process
1.52 6.29e-04 GO:0007243 intracellular protein kinase cascade
1.52 6.29e-04 GO:0023014 signal transduction via phosphorylation event
1.39 7.15e-04 GO:0006468 protein phosphorylation
1.32 7.76e-04 GO:0010646 regulation of cell communication
1.71 9.00e-04 GO:0048011 nerve growth factor receptor signaling pathway
1.46 1.07e-03 GO:0009967 positive regulation of signal transduction
1.21 1.26e-03 GO:0048523 negative regulation of cellular process
1.44 1.50e-03 GO:0023056 positive regulation of signaling
1.44 1.68e-03 GO:0010647 positive regulation of cell communication
1.35 1.80e-03 GO:0016310 phosphorylation
1.35 2.43e-03 GO:0051128 regulation of cellular component organization
1.63 4.11e-03 GO:0000165 MAPKKK cascade
1.38 4.39e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.10 4.51e-03 GO:0044237 cellular metabolic process
1.49 5.59e-03 GO:0007264 small GTPase mediated signal transduction
1.54 1.32e-02 GO:0009141 nucleoside triphosphate metabolic process
1.16 1.41e-02 GO:0019538 protein metabolic process
1.31 1.60e-02 GO:0008219 cell death
1.56 1.78e-02 GO:0010740 positive regulation of intracellular protein kinase cascade
1.54 1.85e-02 GO:0009199 ribonucleoside triphosphate metabolic process
1.30 2.36e-02 GO:0016265 death
1.53 2.59e-02 GO:0009144 purine nucleoside triphosphate metabolic process
1.40 2.84e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.53 2.89e-02 GO:0009205 purine ribonucleoside triphosphate metabolic process
1.35 2.99e-02 GO:0010558 negative regulation of macromolecule biosynthetic process
1.73 3.49e-02 GO:0046039 GTP metabolic process
1.36 3.50e-02 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.33 3.58e-02 GO:0002682 regulation of immune system process
1.75 3.67e-02 GO:0006184 GTP catabolic process
1.33 3.93e-02 GO:0009890 negative regulation of biosynthetic process
1.43 3.96e-02 GO:0072521 purine-containing compound metabolic process
1.38 4.00e-02 GO:0051253 negative regulation of RNA metabolic process
1.79 4.50e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.44 4.62e-02 GO:0006163 purine nucleotide metabolic process
1.38 4.87e-02 GO:0045892 negative regulation of transcription, DNA-dependent

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.09 3.55e-13 GO:0044424 intracellular part
1.08 9.43e-13 GO:0005622 intracellular
1.12 3.50e-12 GO:0005737 cytoplasm
1.10 2.49e-08 GO:0043227 membrane-bounded organelle
1.10 3.20e-08 GO:0043231 intracellular membrane-bounded organelle
1.08 1.67e-07 GO:0043226 organelle
1.08 2.40e-07 GO:0043229 intracellular organelle
1.14 3.45e-07 GO:0005634 nucleus
1.23 1.34e-05 GO:0005829 cytosol
1.11 9.12e-05 GO:0044444 cytoplasmic part
1.22 1.42e-03 GO:0012505 endomembrane system
1.03 9.89e-03 GO:0044464 cell part
1.03 1.04e-02 GO:0005623 cell

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.14 1.54e-12 GO:0005515 protein binding
1.08 7.29e-11 GO:0005488 binding
1.44 2.47e-06 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.42 3.40e-06 GO:0016301 kinase activity
1.37 1.13e-05 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.50 1.40e-04 GO:0004674 protein serine/threonine kinase activity
1.34 1.31e-03 GO:0019899 enzyme binding
1.38 1.44e-03 GO:0004672 protein kinase activity
1.21 3.24e-03 GO:0016740 transferase activity
1.43 3.61e-03 GO:0019904 protein domain specific binding
1.60 1.07e-02 GO:0003924 GTPase activity
1.18 2.05e-02 GO:0017076 purine nucleotide binding
1.18 3.10e-02 GO:0032553 ribonucleotide binding
1.18 3.10e-02 GO:0032555 purine ribonucleotide binding
1.47 3.95e-02 GO:0008134 transcription factor binding