Motif ID: STAT1,3.p3

Z-value: 0.830


Transcription factors associated with STAT1,3.p3:

Gene SymbolEntrez IDGene Name
STAT1 6772 signal transducer and activator of transcription 1, 91kDa
STAT3 6774 signal transducer and activator of transcription 3 (acute-phase response factor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
STAT1chr2_-_1915871270.381.4e-01Click!
STAT3chr17_-_377941020.155.9e-01Click!


Activity profile for motif STAT1,3.p3.

activity profile for motif STAT1,3.p3


Sorted Z-values histogram for motif STAT1,3.p3

Sorted Z-values for motif STAT1,3.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of STAT1,3.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_157313179 2.940 NM_004833
AIM2
absent in melanoma 2
chr19_-_39859997 2.026


chr19_+_39860398 1.695 NM_001012320
NM_018443
ZNF302

zinc finger protein 302

chr5_-_138753443 1.607 NM_016459
MZB1
marginal zone B and B1 cell-specific protein
chr11_+_113672378 1.519 NNMT
nicotinamide N-methyltransferase
chr11_+_113672407 1.465 NNMT
nicotinamide N-methyltransferase
chr1_-_143706196 1.429 PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_143706300 1.393 NM_001002812
NM_014644
NM_001002810
NM_001198834
NM_001195261
PDE4DIP




phosphodiesterase 4D interacting protein




chr1_-_143706265 1.347 PDE4DIP
phosphodiesterase 4D interacting protein
chrX_-_154216929 1.062 NM_001289
CLIC2
chloride intracellular channel 2
chr1_-_158883666 0.890 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr5_+_139924224 0.870 SLC35A4
solute carrier family 35, member A4
chr14_+_99309688 0.851 EML1
echinoderm microtubule associated protein like 1
chr17_-_24491521 0.793 MYO18A
myosin XVIIIA
chr16_+_54072969 0.773 NM_001127891
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr19_+_49309350 0.727 NM_013362
ZNF225
zinc finger protein 225
chr12_-_119172339 0.723 NM_025157
PXN
paxillin
chr8_+_27238979 0.658 NM_173175
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr22_-_29833484 0.606 NM_080430
SELM
selenoprotein M
chr11_-_62218759 0.605 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr22_+_19191875 0.592 MED15
mediator complex subunit 15
chr17_-_73867748 0.574 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr22_+_19191898 0.570 MED15
mediator complex subunit 15
chr22_+_19191884 0.558 NM_001003891
NM_015889
MED15

mediator complex subunit 15

chr22_+_19191886 0.558 MED15
mediator complex subunit 15
chr22_+_19191859 0.542 MED15
mediator complex subunit 15
chr15_+_89300973 0.531 RCCD1
RCC1 domain containing 1
chr3_+_123882355 0.521 NM_017554
PARP14
poly (ADP-ribose) polymerase family, member 14
chr12_-_8271460 0.510 NM_018088
FAM90A1
family with sequence similarity 90, member A1
chr1_+_240078655 0.496 NM_003686
NM_006027
EXO1

exonuclease 1

chr4_-_129429433 0.495 NM_006320
PGRMC2
progesterone receptor membrane component 2
chr11_-_64247230 0.482 NM_015080
NM_138732
NRXN2

neurexin 2

chr22_-_49041786 0.477 MAPK12
mitogen-activated protein kinase 12
chr15_+_89300995 0.476 RCCD1
RCC1 domain containing 1
chr9_+_131937163 0.471 GPR107
G protein-coupled receptor 107
chr19_+_49198916 0.442 NM_006300
ZNF230
zinc finger protein 230
chr20_-_42713663 0.435 ADA
adenosine deaminase
chr11_-_605920 0.422 IRF7
interferon regulatory factor 7
chr10_-_90740935 0.407 NM_001141945
ACTA2
actin, alpha 2, smooth muscle, aorta
chr10_+_90741024 0.407 FAS
Fas (TNF receptor superfamily, member 6)
chr13_-_94751573 0.395 NM_001105515
NM_005845
ABCC4

ATP-binding cassette, sub-family C (CFTR/MRP), member 4

chr10_-_61139328 0.393 NM_194298
LOC100129721
SLC16A9
hypothetical protein LOC100129721
solute carrier family 16, member 9 (monocarboxylic acid transporter 9)
chr2_+_170074457 0.390 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr11_-_121492010 0.378 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr8_-_42742729 0.365 NM_004198
CHRNA6
cholinergic receptor, nicotinic, alpha 6
chr19_-_45022993 0.352 FBL
fibrillarin
chr1_-_11841476 0.339 NM_002521
NPPB
natriuretic peptide B
chr11_+_32068990 0.327 NM_002901
RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr19_-_49309102 0.324 LOC100379224
hypothetical LOC100379224
chr12_+_11694172 0.323 ETV6
ets variant 6
chr5_-_180220881 0.317 NM_001172638
NM_152283
ZFP62

zinc finger protein 62 homolog (mouse)

chr11_-_605998 0.315 NM_001572
NM_004029
IRF7

interferon regulatory factor 7

chr22_+_23333610 0.314 NM_001032365
GGT1
gamma-glutamyltransferase 1
chrX_+_102749489 0.313 NM_001006933
NM_032926
TCEAL3

transcription elongation factor A (SII)-like 3

chr4_+_130236731 0.306 NM_001099783
C4orf33
chromosome 4 open reading frame 33
chr11_+_32069183 0.292 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr14_-_19951417 0.290 NM_007110
TEP1
telomerase-associated protein 1
chr11_-_605649 0.272 NM_004031
IRF7
interferon regulatory factor 7
chr19_+_10242763 0.272 ICAM1
intercellular adhesion molecule 1
chr3_-_172109119 0.270 NM_020390
EIF5A2
eukaryotic translation initiation factor 5A2
chr19_-_61596681 0.269 NM_144690
ZNF582
zinc finger protein 582
chr8_+_11388918 0.268 NM_001715
BLK
B lymphoid tyrosine kinase
chr11_+_47958835 0.258 PTPRJ
protein tyrosine phosphatase, receptor type, J
chr22_-_48437081 0.248 C22orf34
chromosome 22 open reading frame 34
chr1_-_52272020 0.244 NM_138417
KTI12
KTI12 homolog, chromatin associated (S. cerevisiae)
chr19_+_49290319 0.229 NM_013398
ZNF224
zinc finger protein 224
chr1_-_43606276 0.223 NM_022821
ELOVL1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr15_-_41409979 0.217 NM_014793
LCMT2
leucine carboxyl methyltransferase 2
chr5_+_149867866 0.213 NM_001543
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr3_-_121065112 0.213


chr19_+_45194782 0.211 NM_178544
ZNF546
zinc finger protein 546
chr19_+_49408523 0.207 NM_182490
ZNF227
zinc finger protein 227
chr6_+_31648071 0.204 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr12_-_107238568 0.202 NM_001142345
CMKLR1
chemokine-like receptor 1
chr16_-_3049336 0.199


chr5_-_177592406 0.199 NM_153373
AGXT2L2
alanine-glyoxylate aminotransferase 2-like 2
chr11_+_71387572 0.196 NM_001039659
NM_001039660
NM_173042
IL18BP


interleukin 18 binding protein


chr2_+_149603226 0.195 NM_177964
LYPD6B
LY6/PLAUR domain containing 6B
chr19_-_53941835 0.194 NM_182575
IZUMO1
izumo sperm-egg fusion 1
chr1_+_194887630 0.193 NM_000186
NM_001014975
CFH

complement factor H

chr9_+_5440455 0.190 NM_014143
CD274
CD274 molecule
chr15_+_41410163 0.187 NM_001012969
NM_001159280
ADAL

adenosine deaminase-like

chr6_+_97117144 0.186 NM_001170807
NM_020482
FHL5

four and a half LIM domains 5

chr6_-_132764257 0.185 NM_015529
MOXD1
monooxygenase, DBH-like 1
chr9_-_130078017 0.176 NM_004486
GOLGA2
golgin A2
chr15_+_30797466 0.172 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr22_+_19191964 0.170 MED15
mediator complex subunit 15
chr4_+_52403922 0.168 NM_001040402
NM_015115
DCUN1D4

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

chr9_-_35608300 0.159 NM_001782
CD72
CD72 molecule
chrX_-_134013644 0.158 NM_001078172
NM_001134321
FAM127B

family with sequence similarity 127, member B

chr1_+_240078094 0.157 NM_130398
EXO1
exonuclease 1
chr3_-_171070314 0.157 NM_024727
LRRC31
leucine rich repeat containing 31
chr5_-_139924013 0.155 APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr19_-_3935152 0.152 EEF2
eukaryotic translation elongation factor 2
chr3_-_147696411 0.150 NM_020359
PLSCR2
phospholipid scramblase 2
chr5_-_177592326 0.150 AGXT2L2
alanine-glyoxylate aminotransferase 2-like 2
chr2_+_102401580 0.149 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr17_-_8020332 0.149 NM_032354
NM_183065
TMEM107

transmembrane protein 107

chr5_+_178300799 0.147 NM_001178089
NM_001178090
NM_182594
ZNF454


zinc finger protein 454


chr12_-_47735373 0.146 NM_003482
MLL2
myeloid/lymphoid or mixed-lineage leukemia 2
chr4_+_25267183 0.145 NM_001177999
SLC34A2
solute carrier family 34 (sodium phosphate), member 2
chr5_-_139924229 0.144 NM_006051
NM_133172
NM_133173
NM_133174
APBB3



amyloid beta (A4) precursor protein-binding, family B, member 3



chr6_-_28412130 0.144 NM_030899
ZNF323
zinc finger protein 323
chr3_-_172109075 0.141 EIF5A2
eukaryotic translation initiation factor 5A2
chr5_-_177592157 0.140 AGXT2L2
alanine-glyoxylate aminotransferase 2-like 2
chr4_+_41235077 0.137 LIMCH1
LIM and calponin homology domains 1
chr1_-_210070736 0.136 NM_014873
LPGAT1
lysophosphatidylglycerol acyltransferase 1
chr7_-_148788799 0.134 NM_015694
ZNF777
zinc finger protein 777
chrX_+_154097894 0.133 NM_003372
VBP1
von Hippel-Lindau binding protein 1
chr8_-_102872354 0.133 NCALD
neurocalcin delta
chr16_-_3707450 0.132 NM_016292
TRAP1
TNF receptor-associated protein 1
chr9_+_135276940 0.130 NM_139025
NM_139026
NM_139027
ADAMTS13


ADAM metallopeptidase with thrombospondin type 1 motif, 13


chr19_-_4782711 0.129 NM_182919
TICAM1
toll-like receptor adaptor molecule 1
chr14_-_104718565 0.128 NM_177533
NUDT14
nudix (nucleoside diphosphate linked moiety X)-type motif 14
chrX_+_106030049 0.128 NM_001171092
CLDN2
claudin 2
chr4_-_145281237 0.127 NM_002099
GYPA
glycophorin A (MNS blood group)
chr1_+_112811562 0.127 NM_004185
WNT2B
wingless-type MMTV integration site family, member 2B
chr19_-_11550576 0.126 NM_001111034
ACP5
acid phosphatase 5, tartrate resistant
chr19_-_4853878 0.120 NM_001080523
ARRDC5
arrestin domain containing 5
chr9_-_88751923 0.119 NM_002048
GAS1
growth arrest-specific 1
chr3_+_130081149 0.118 ACAD9
acyl-CoA dehydrogenase family, member 9
chr3_+_130081210 0.115 ACAD9
acyl-CoA dehydrogenase family, member 9
chr1_-_159786150 0.113 FCGR3A
Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
chr17_-_39333490 0.113 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr6_-_31007905 0.113 NM_205854
SFTA2
surfactant associated 2
chr6_+_139391511 0.112 NM_021243
C6orf115
chromosome 6 open reading frame 115
chr3_+_130081022 0.112 NM_014049
ACAD9
acyl-CoA dehydrogenase family, member 9
chrX_-_30505804 0.112 NM_025159
CXorf21
chromosome X open reading frame 21
chr19_-_49644470 0.111 NM_014518
ZNF229
zinc finger protein 229
chr6_+_139391570 0.111 C6orf115
chromosome 6 open reading frame 115
chr1_-_205186330 0.109 NM_002644
PIGR
polymeric immunoglobulin receptor
chr12_-_49689255 0.109 SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chrX_+_48317772 0.107 NM_006743
RBM3
RNA binding motif (RNP1, RRM) protein 3
chr19_+_53559468 0.107 NM_012451
SYNGR4
synaptogyrin 4
chr19_+_54669629 0.106 FLT3LG
fms-related tyrosine kinase 3 ligand
chrX_+_134803450 0.106 NM_018666
SAGE1
sarcoma antigen 1
chr3_+_130081161 0.105 ACAD9
acyl-CoA dehydrogenase family, member 9
chr12_-_52356375 0.104 NM_005176
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr1_+_54291847 0.103 NM_153035
TCEANC2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr19_-_53841064 0.103 NM_001217
CA11
carbonic anhydrase XI
chr19_+_10242516 0.102 NM_000201
ICAM1
intercellular adhesion molecule 1
chr9_+_124463665 0.101 NM_001005236
OR1L1
olfactory receptor, family 1, subfamily L, member 1
chr14_+_77939845 0.101 NM_004796
NRXN3
neurexin 3
chr13_+_24844084 0.098 NM_016529
ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr6_+_152168500 0.097 NM_001122741
ESR1
estrogen receptor 1
chr3_+_130081130 0.096 ACAD9
acyl-CoA dehydrogenase family, member 9
chr1_+_34405070 0.095 NM_032884
C1orf94
chromosome 1 open reading frame 94
chr1_-_201422450 0.095 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr8_-_102872372 0.094 NCALD
neurocalcin delta
chr12_-_54869511 0.093 SMARCC2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
chr12_-_121404968 0.093 CLIP1
CAP-GLY domain containing linker protein 1
chr3_+_130081187 0.092 ACAD9
acyl-CoA dehydrogenase family, member 9
chr4_-_185632610 0.091 NM_002199
IRF2
interferon regulatory factor 2
chr16_+_4546491 0.091 NM_001145011
LOC342346
hypothetical protein LOC342346
chr19_-_844215 0.089 NM_005481
MED16
mediator complex subunit 16
chr1_-_6376360 0.088 NM_007274
ACOT7
acyl-CoA thioesterase 7
chr14_+_66777578 0.087 NM_022474
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chrX_+_119622570 0.086 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr1_-_6502655 0.085 NM_198681
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr9_-_133574928 0.085 NM_198679
RAPGEF1
Rap guanine nucleotide exchange factor (GEF) 1
chr12_+_66328760 0.082 NM_003583
NM_006482
DYRK2

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2

chr19_-_60664860 0.082 NM_001136201
NM_001136202
NM_024710
ISOC2


isochorismatase domain containing 2


chr1_-_154226484 0.081 ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr19_+_3713671 0.081 MRPL54
mitochondrial ribosomal protein L54
chr1_+_24944346 0.080 NM_013943
CLIC4
chloride intracellular channel 4
chr20_+_34019942 0.077 NM_080834
C20orf152
chromosome 20 open reading frame 152
chr1_-_201422436 0.077 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_159786441 0.077 NM_000569
NM_001127592
FCGR3A

Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

chr12_-_52179462 0.077 NM_001193511
NM_006301
MAP3K12

mitogen-activated protein kinase kinase kinase 12

chr15_-_62173041 0.077 NM_001014812
NM_032231
FAM96A

family with sequence similarity 96, member A

chrX_-_62891066 0.076 ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr3_-_81893486 0.076 GBE1
glucan (1,4-alpha-), branching enzyme 1
chr1_-_54291634 0.073 NM_004872
TMEM59
transmembrane protein 59
chr22_+_16501540 0.073 BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr16_+_66129481 0.073 FAM65A
family with sequence similarity 65, member A
chr1_+_231152942 0.073 NM_032324
NTPCR
nucleoside-triphosphatase, cancer-related
chr19_-_43412152 0.069 NM_001135156
DPF1
D4, zinc and double PHD fingers family 1
chr7_-_149631001 0.068 NM_001164459
ACTR3C
ARP3 actin-related protein 3 homolog C (yeast)
chr9_+_130078321 0.068 C9orf119
chromosome 9 open reading frame 119
chr19_+_49221333 0.068 NM_001129996
NM_013360
ZNF284
ZNF222

zinc finger protein 284
zinc finger protein 222

chr4_+_120029426 0.067 NM_001128933
NM_001128934
NM_133477
SYNPO2


synaptopodin 2


chr5_-_111340421 0.066 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr1_-_29381223 0.066 NM_005626
SRSF4
serine/arginine-rich splicing factor 4
chr1_-_71285847 0.066 NM_001126044
NM_198714
NM_198715
NM_198716
NM_198717
NM_198718
NM_198719
PTGER3






prostaglandin E receptor 3 (subtype EP3)






chr2_+_30523586 0.066 NM_182551
NM_001002257
LCLAT1

lysocardiolipin acyltransferase 1

chr12_+_92488932 0.065 SOCS2
suppressor of cytokine signaling 2
chr22_-_36212160 0.065 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr22_+_16501446 0.065 NM_015367
BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr7_-_87774130 0.064 NM_024636
STEAP4
STEAP family member 4
chr15_-_41589958 0.064 NM_005657
TP53BP1
tumor protein p53 binding protein 1
chr19_+_46992361 0.064 NM_001815
CEACAM3
carcinoembryonic antigen-related cell adhesion molecule 3
chr19_+_44959073 0.064 NM_001143832
LEUTX
leucine twenty homeobox
chr12_+_100795213 0.063 NM_018370
DRAM1
DNA-damage regulated autophagy modulator 1
chr2_+_173648751 0.063 NM_016653
NM_133646
ZAK

sterile alpha motif and leucine zipper containing kinase AZK

chr3_-_42719322 0.062 NM_020707
HHATL
hedgehog acyltransferase-like
chr1_-_54291474 0.062 TMEM59
transmembrane protein 59
chr2_-_85948287 0.061 NM_001042437
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr1_+_231152995 0.060 NTPCR
nucleoside-triphosphatase, cancer-related
chr15_+_76228788 0.060 IDH3A
isocitrate dehydrogenase 3 (NAD+) alpha
chr1_+_12002138 0.060 MIIP
migration and invasion inhibitory protein

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.