Motif ID: EOMES.p2

Z-value: 1.083


Transcription factors associated with EOMES.p2:

Gene SymbolEntrez IDGene Name
EOMES 8320 eomesodermin

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
EOMESchr3_-_277392010.381.5e-01Click!


Activity profile for motif EOMES.p2.

activity profile for motif EOMES.p2


Sorted Z-values histogram for motif EOMES.p2

Sorted Z-values for motif EOMES.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EOMES.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_105511615 2.737 NM_001004317
 LIN28B
lin-28 homolog B (C. elegans)
chr2_+_171280046 2.218 NM_001003845
 SP5
Sp5 transcription factor
chr2_-_74606819 2.007 NM_133637
 DQX1
DEAQ box RNA-dependent ATPase 1
chr2_+_171280944 1.984 SP5
Sp5 transcription factor
chr2_+_171280182 1.941


chr10_+_4995685 1.824 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr4_-_186969041 1.703 NM_001145672
 SORBS2
sorbin and SH3 domain containing 2
chr4_-_186969202 1.664 NM_001145671
 SORBS2
sorbin and SH3 domain containing 2
chr14_+_94148466 1.508 NM_001085
 SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr17_-_40858775 1.474 NM_199282
 ARHGAP27
Rho GTPase activating protein 27
chr10_+_4995597 1.443 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr3_+_10832867 1.280 NM_014229
 SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr2_+_228386800 1.265 NM_001130046
NM_004591
 CCL20

chemokine (C-C motif) ligand 20

chr20_-_22513050 1.243 NM_021784
 FOXA2
forkhead box A2
chr11_-_65070625 1.240 LTBP3
latent transforming growth factor beta binding protein 3
chr12_+_130004404 1.070 NM_198827
 GPR133
G protein-coupled receptor 133
chr14_-_22516271 1.064 NM_198086
 JUB
jub, ajuba homolog (Xenopus laevis)
chr14_-_23107106 1.060 NM_003917
 AP1G2
adaptor-related protein complex 1, gamma 2 subunit
chr1_+_148496792 1.022 NM_012113
 CA14
carbonic anhydrase XIV
chr10_+_114125955 0.971 ACSL5
acyl-CoA synthetase long-chain family member 5

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 5 of 5 entries
enrichment   p-value GO term description
5.56 1.16e-02 GO:0045840 positive regulation of mitosis
5.56 1.16e-02 GO:0051785 positive regulation of nuclear division
1.55 1.38e-02 GO:0007154 cell communication
1.26 5.48e-03 GO:0023052 signaling
1.22 1.85e-03 GO:0032501 multicellular organismal process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
5.21 1.54e-02 GO:0033764 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
1.89 3.70e-02 GO:0022836 gated channel activity
1.85 6.75e-03 GO:0015267 channel activity
1.84 7.26e-03 GO:0022803 passive transmembrane transporter activity
1.79 2.49e-02 GO:0022838 substrate-specific channel activity
1.51 3.03e-02 GO:0022891 substrate-specific transmembrane transporter activity
1.48 4.25e-02 GO:0022857 transmembrane transporter activity
1.47 2.85e-02 GO:0022892 substrate-specific transporter activity
1.43 3.01e-02 GO:0005215 transporter activity