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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: E2F1..5.p2

Z-value: 3.824

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_-_23729871	7.677		E2F2	E2F transcription factor 2
chr1_-_23730298	7.256	NM_004091	E2F2	E2F transcription factor 2
chr6_+_135544138	6.194	NM_001130172 NM_001130173 NM_001161656 NM_001161657 NM_001161658 NM_001161659 NM_001161660 NM_005375	MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr6_+_135544214	6.043		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr6_+_135544170	6.012		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr11_-_33847507	4.993		LMO2	LIM domain only 2 (rhombotin-like 1)
chr22_+_18485145	4.513		RANBP1	RAN binding protein 1
chr22_+_18485076	4.451		RANBP1	RAN binding protein 1
chr11_-_19219000	4.407	NM_024680	E2F8	E2F transcription factor 8
chr22_+_18485057	4.378		RANBP1	RAN binding protein 1
chr22_+_18485095	4.186		RANBP1	RAN binding protein 1
chr22_+_18485068	4.082		RANBP1	RAN binding protein 1
chr22_-_18484695	3.863		TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr11_-_19219720	3.820		E2F8	E2F transcription factor 8
chr22_+_34126104	3.673	NM_006739	MCM5	minichromosome maintenance complex component 5
chr7_+_50314801	3.673	NM_006060	IKZF1	IKAROS family zinc finger 1 (Ikaros)
chr22_+_34126154	3.600		MCM5	minichromosome maintenance complex component 5
chr10_+_124885556	3.399	NM_001105574	HMX3	H6 family homeobox 3
chr20_-_35157744	3.394		RBL1	retinoblastoma-like 1 (p107)
chr11_-_33847834	3.269		LMO2	LIM domain only 2 (rhombotin-like 1)
chr22_+_18484810	3.262	NM_002882	RANBP1	RAN binding protein 1
chr20_-_35157815	3.260	NM_002895 NM_183404	RBL1	retinoblastoma-like 1 (p107)
chr1_+_3558958	3.230	NM_005427	TP73	tumor protein p73
chr9_-_122679387	3.177	NM_001009936 NM_015651	PHF19	PHD finger protein 19
chr11_-_33847937	3.153	NM_001142316	LMO2	LIM domain only 2 (rhombotin-like 1)
chr22_-_18484744	3.152	NM_022727 NM_182984	TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr1_-_36008009	2.958	NM_001190481 NM_022111	CLSPN	claspin
chr11_-_33848013	2.864		LMO2	LIM domain only 2 (rhombotin-like 1)
chr10_+_62208256	2.765		CDK1	cyclin-dependent kinase 1
chr9_-_122679283	2.688		PHF19	PHD finger protein 19
chr22_+_34126294	2.685		MCM5	minichromosome maintenance complex component 5
chr20_-_31737731	2.633		E2F1	E2F transcription factor 1
chr6_-_52257500	2.620	NM_002388	MCM3	minichromosome maintenance complex component 3
chr12_-_75983329	2.573	NM_203394	E2F7	E2F transcription factor 7
chr6_-_52257475	2.539		MCM3	minichromosome maintenance complex component 3
chr6_-_52257431	2.522		MCM3	minichromosome maintenance complex component 3
chr22_-_37296012	2.501	NM_007068	DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)
chr16_-_30010705	2.471	NM_004608	TBX6	T-box 6
chr6_+_27208763	2.466	NM_021064	HIST1H2AG	histone cluster 1, H2ag
chr2_-_136350404	2.465		MCM6	minichromosome maintenance complex component 6
chr2_+_74635019	2.452	NM_001381	DOK1	docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr7_-_99537362	2.450	NM_005916	MCM7	minichromosome maintenance complex component 7
chr6_+_31815703	2.399	NM_002441 NM_025259 NM_172165 NM_172166	MSH5-C6ORF26 MSH5	MSH5-C6orf26 read-through transcript mutS homolog 5 (E. coli)
chr17_-_43977273	2.329	NM_002145	HOXB2	homeobox B2
chr6_-_27208507	2.294	NM_021058	HIST1H2BJ	histone cluster 1, H2bj
chr6_+_20510019	2.250	NM_001949	E2F3	E2F transcription factor 3
chr6_-_26358811	2.241	NM_021018	HIST1H3F	histone cluster 1, H3f
chr20_-_31737815	2.196	NM_005225	E2F1	E2F transcription factor 1
chr10_+_62208094	2.187	NM_001170406 NM_001170407 NM_001786 NM_033379	CDK1	cyclin-dependent kinase 1
chr19_+_4860447	2.133	NM_001048201	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chrX_-_135677022	2.105		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr2_-_136350472	2.098	NM_005915	MCM6	minichromosome maintenance complex component 6
chr1_-_26105230	2.081	NM_203401	STMN1	stathmin 1
chrX_-_53465847	2.075		SMC1A	structural maintenance of chromosomes 1A
chr5_-_176671897	2.066	NM_001142935 NM_031300	MXD3	MAX dimerization protein 3
chr7_+_120378052	2.062	NM_019071 NM_198267	ING3	inhibitor of growth family, member 3
chr19_-_60587414	2.062	NM_001190764	LOC388564	hypothetical protein LOC388564
chr6_+_27222839	2.041	NM_080596	HIST1H2AH	histone cluster 1, H2ah
chr2_+_10180145	2.036	NM_001165931	RRM2	ribonucleotide reductase M2
chr3_+_128799961	2.020		MCM2	minichromosome maintenance complex component 2
chr19_+_4861166	1.945		UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr2_+_10180304	1.930	NM_001034	RRM2	ribonucleotide reductase M2
chr7_+_99537065	1.887	NM_004722	AP4M1	adaptor-related protein complex 4, mu 1 subunit
chr6_-_27222556	1.881	NM_080593	HIST1H2BK	histone cluster 1, H2bk
chr1_-_226712140	1.851	NM_033445	HIST3H2A	histone cluster 3, H2a
chr1_+_226712430	1.841	NM_175055	HIST3H2BB	histone cluster 3, H2bb
chr17_+_27288152	1.834	NM_015355	SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr17_-_44042924	1.803		HOXB7	homeobox B7
chr10_-_25281510	1.797	NM_020200	PRTFDC1	phosphoribosyl transferase domain containing 1
chr12_+_107047594	1.783	NM_014653	WSCD2	WSC domain containing 2
chr19_-_10540620	1.778	NM_001800 NM_079421	CDKN2D	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr1_-_28113540	1.774		RPA2	replication protein A2, 32kDa
chr7_-_158190193	1.728	NM_017760	NCAPG2	non-SMC condensin II complex, subunit G2
chr1_-_28113817	1.727	NM_002946	RPA2	replication protein A2, 32kDa
chr17_+_27288167	1.712		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr3_+_144321286	1.706	NM_004267	CHST2	carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
chr7_-_106088565	1.690	NM_175884	FLJ36031	hypothetical protein FLJ36031
chr10_-_57791000	1.688		ZWINT	ZW10 interactor
chr3_-_140148671	1.684	NM_023067	FOXL2	forkhead box L2
chr4_+_129950222	1.681	NM_024900 NM_199320	PHF17	PHD finger protein 17
chr7_-_99536966	1.681		MCM7	minichromosome maintenance complex component 7
chr3_+_16901455	1.664	NM_001144382	PLCL2	phospholipase C-like 2
chr7_-_99536929	1.664		MCM7	minichromosome maintenance complex component 7
chr10_-_57791025	1.661	NM_001005413 NM_007057 NM_032997	ZWINT	ZW10 interactor
chr22_-_19685998	1.658		THAP7	THAP domain containing 7
chr16_+_87397686	1.644	NM_030928	CDT1	chromatin licensing and DNA replication factor 1
chr17_-_44043278	1.629		HOXB7	homeobox B7
chr1_-_47552238	1.627	NM_001048166 NM_003035	STIL	SCL/TAL1 interrupting locus
chr17_+_27288253	1.625		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr2_-_144991556	1.613		ZEB2	zinc finger E-box binding homeobox 2
chr16_+_28798735	1.610		ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr1_+_149309703	1.607	NM_144618	GABPB2	GA binding protein transcription factor, beta subunit 2
chr19_-_10166600	1.605		DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr17_-_44043361	1.587	NM_004502	HOXB7	homeobox B7
chr4_-_56197115	1.586	NM_006681	NMU	neuromedin U
chr15_+_39008822	1.582	NM_019074	DLL4	delta-like 4 (Drosophila)
chr19_+_4861339	1.578	NM_013282	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr7_-_99536852	1.551		MCM7	minichromosome maintenance complex component 7
chr7_+_88226617	1.546	NM_181646	ZNF804B	zinc finger protein 804B
chr2_+_74635354	1.545		DOK1	docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr17_+_27288374	1.519
chr17_+_27288178	1.513		SUZ12	suppressor of zeste 12 homolog (Drosophila)
chr9_-_97119677	1.477	NM_000136	FANCC	Fanconi anemia, complementation group C
chr19_-_10166536	1.471		DNMT1	DNA (cytosine-5-)-methyltransferase 1
chrX_+_48440079	1.471		SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)
chr2_-_144991386	1.444		ZEB2	zinc finger E-box binding homeobox 2
chr11_+_817584	1.438	NM_173584	EFCAB4A	EF-hand calcium binding domain 4A
chr16_+_87397715	1.428		CDT1	chromatin licensing and DNA replication factor 1
chr3_-_44778099	1.413	NM_020696	KIAA1143	KIAA1143
chrX_+_48440068	1.382	NM_003173	SUV39H1	suppressor of variegation 3-9 homolog 1 (Drosophila)
chr3_+_140148765	1.378	NM_001040061	C3orf72	chromosome 3 open reading frame 72
chr13_-_78075683	1.378	NM_006237	POU4F1	POU class 4 homeobox 1
chr7_+_128861471	1.363	NM_001134336 NM_020704	FAM40B	family with sequence similarity 40, member B
chr1_-_26105477	1.362	NM_001145454 NM_005563	STMN1	stathmin 1
chr9_+_129962292	1.351	NM_024112	C9orf16	chromosome 9 open reading frame 16
chr1_+_210275752	1.349		DTL	denticleless homolog (Drosophila)
chr3_+_44778284	1.348		KIF15	kinesin family member 15
chr6_-_153345786	1.345	NM_012177	FBXO5	F-box protein 5
chr7_-_148212336	1.333	NM_004456 NM_152998	EZH2	enhancer of zeste homolog 2 (Drosophila)
chr7_-_148212292	1.325		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr3_+_128799964	1.321		MCM2	minichromosome maintenance complex component 2
chr4_+_154485224	1.320	NM_032117	MND1	meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr4_-_105631915	1.316	NM_025212	CXXC4	CXXC finger protein 4
chr5_-_54558899	1.315	NM_001190787	LOC345643	hypothetical LOC345643
chrX_-_133758812	1.308	NM_001166599 NM_001166600 NM_001170757	FAM122B	family with sequence similarity 122B
chr7_-_148212312	1.300		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr3_+_128799902	1.300	NM_004526	MCM2	minichromosome maintenance complex component 2
chr7_-_148212230	1.293		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr8_+_55533047	1.289	NM_022454	SOX17	SRY (sex determining region Y)-box 17
chr15_+_39739933	1.287		MGA	MAX gene associated
chr13_+_33290254	1.276		RFC3	replication factor C (activator 1) 3, 38kDa
chr15_+_38550451	1.272	NM_130468	CHST14	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr19_+_34994701	1.268	NM_001238	CCNE1	cyclin E1
chrX_+_130985316	1.266	NM_001042452	MST4	serine/threonine protein kinase MST4
chrX_+_24621964	1.262		POLA1	polymerase (DNA directed), alpha 1, catalytic subunit
chr3_+_44778212	1.258	NM_020242	KIF15	kinesin family member 15
chr7_-_148212310	1.258		EZH2	enhancer of zeste homolog 2 (Drosophila)
chr12_-_131773972	1.256	NM_006231	POLE	polymerase (DNA directed), epsilon
chr2_+_173927783	1.251	NM_031942 NM_145810	CDCA7	cell division cycle associated 7
chrX_+_130984912	1.239	NM_001042453 NM_016542	MST4	serine/threonine protein kinase MST4
chr19_-_10540328	1.231		CDKN2D	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr5_+_79986049	1.220	NM_002439	MSH3	mutS homolog 3 (E. coli)
chr19_-_10166645	1.217	NM_001130823 NM_001379	DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr1_+_210275735	1.216		DTL	denticleless homolog (Drosophila)
chr9_-_98220360	1.209		ZNF367	zinc finger protein 367
chr5_-_79986104	1.205		DHFR	dihydrofolate reductase
chr1_-_203985701	1.199		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr2_+_177965734	1.189		AGPS	alkylglycerone phosphate synthase
chr8_+_69026895	1.188		PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chrX_-_53466273	1.186		SMC1A	structural maintenance of chromosomes 1A
chr8_+_69027277	1.184		PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr1_-_26105954	1.183	NM_203399	STMN1	stathmin 1
chr5_+_79986254	1.179		MSH3	mutS homolog 3 (E. coli)
chr1_-_203985896	1.179		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr5_+_79986227	1.175		MSH3	mutS homolog 3 (E. coli)
chr1_+_199259664	1.174
chr3_-_150286812	1.171	NM_003071 NM_139048	HLTF	helicase-like transcription factor
chr1_-_203985932	1.170
chr5_-_79986063	1.158		DHFR	dihydrofolate reductase
chr8_-_124477869	1.154	NM_014109	ATAD2	ATPase family, AAA domain containing 2
chr19_-_6453224	1.149	NM_006087	TUBB4	tubulin, beta 4
chr2_+_27293846	1.141		CAD	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr2_+_27293737	1.136	NM_004341	CAD	carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr15_+_89061579	1.133	NM_000057	BLM	Bloom syndrome, RecQ helicase-like
chrX_+_24621984	1.133	NM_016937	POLA1	polymerase (DNA directed), alpha 1, catalytic subunit
chr5_+_79986222	1.130		MSH3	mutS homolog 3 (E. coli)
chr7_+_116380790	1.125		ST7	suppression of tumorigenicity 7
chr22_-_18484428	1.122		TRMT2A	TRM2 tRNA methyltransferase 2 homolog A (S. cerevisiae)
chr1_-_203985780	1.119		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr5_-_79986539	1.115	NM_000791	DHFR	dihydrofolate reductase
chr1_-_100370994	1.109	NM_194292	SASS6	spindle assembly 6 homolog (C. elegans)
chr6_-_27883662	1.106	NM_003519	HIST1H2BL	histone cluster 1, H2bl
chr13_+_113287048	1.101	NM_007111	TFDP1	transcription factor Dp-1
chr8_+_69027166	1.101		PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr5_-_176671437	1.101		MXD3	MAX dimerization protein 3
chrX_+_152891184	1.097	NM_003492	TMEM187	transmembrane protein 187
chr15_+_62539831	1.097		ZNF609	zinc finger protein 609
chr9_+_125813849	1.093		LHX2	LIM homeobox 2
chr10_-_98470164	1.092	NM_152309	PIK3AP1	phosphoinositide-3-kinase adaptor protein 1
chr17_+_26183074	1.091	NM_024857	ATAD5	ATPase family, AAA domain containing 5
chr8_-_27751207	1.090	NM_018492	PBK	PDZ binding kinase
chr12_-_131774061	1.090		POLE	polymerase (DNA directed), epsilon
chr1_+_210275541	1.089	NM_016448	DTL	denticleless homolog (Drosophila)
chr11_-_14869761	1.082		CYP2R1	cytochrome P450, family 2, subfamily R, polypeptide 1
chr19_-_46551607	1.077		TGFB1	transforming growth factor, beta 1
chr14_-_54727958	1.075	NM_001146015 NM_014750	DLGAP5	discs, large (Drosophila) homolog-associated protein 5
chr15_+_30694982	1.074	NM_014783 NM_199357	ARHGAP11A	Rho GTPase activating protein 11A
chr16_-_2970390	1.074		PKMYT1	protein kinase, membrane associated tyrosine/threonine 1
chr4_+_134292630	1.073		PCDH10	protocadherin 10
chr7_-_44854222	1.073	NM_012412 NM_138635 NM_201436 NM_201516 NM_201517	H2AFV	H2A histone family, member V
chr19_+_50601306	1.073	NM_012099	CD3EAP	CD3e molecule, epsilon associated protein
chr1_-_203985752	1.065		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr17_+_35697656	1.059		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr1_-_203985963	1.059	NM_022731	NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr3_-_48204332	1.057		CDC25A	cell division cycle 25 homolog A (S. pombe)
chr11_+_65414677	1.043		CCDC85B	coiled-coil domain containing 85B
chr17_-_16197433	1.042	NM_181716	CENPV	centromere protein V
chr8_+_69027143	1.041	NM_024870 NM_025170	PREX2	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr15_+_39739864	1.041	NM_001080541 NM_001164273	MGA	MAX gene associated
chr6_+_84799969	1.040	NM_138409	MRAP2	melanocortin 2 receptor accessory protein 2

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
2.65	4.87e-35	GO:0007049	cell cycle
2.99	8.13e-32	GO:0022403	cell cycle phase
2.79	2.92e-31	GO:0022402	cell cycle process
1.90	7.08e-27	GO:0090304	nucleic acid metabolic process
2.84	1.53e-24	GO:0051276	chromosome organization
1.74	1.55e-24	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.89	2.79e-24	GO:0006259	DNA metabolic process
2.90	2.94e-24	GO:0000278	mitotic cell cycle
1.48	3.37e-19	GO:0044260	cellular macromolecule metabolic process
1.59	1.07e-18	GO:0034641	cellular nitrogen compound metabolic process
3.34	5.09e-18	GO:0051325	interphase
3.35	7.30e-18	GO:0051329	interphase of mitotic cell cycle
1.56	1.70e-17	GO:0006807	nitrogen compound metabolic process
1.87	2.86e-17	GO:0006996	organelle organization
2.88	2.87e-17	GO:0000279	M phase
4.05	3.26e-17	GO:0006260	DNA replication
4.79	1.35e-14	GO:0065004	protein-DNA complex assembly
2.56	1.54e-14	GO:0006974	response to DNA damage stimulus
4.65	1.84e-14	GO:0071824	protein-DNA complex subunit organization
4.97	2.13e-14	GO:0031497	chromatin assembly
2.94	2.56e-14	GO:0010564	regulation of cell cycle process
2.95	3.17e-14	GO:0006281	DNA repair
2.37	5.94e-14	GO:0051726	regulation of cell cycle
4.30	8.02e-14	GO:0006323	DNA packaging
3.96	2.66e-13	GO:0071103	DNA conformation change
4.60	1.09e-12	GO:0034728	nucleosome organization
4.82	1.27e-12	GO:0006334	nucleosome assembly
1.35	1.85e-12	GO:0043170	macromolecule metabolic process
2.52	2.01e-12	GO:0006325	chromatin organization
3.96	2.45e-12	GO:0000082	G1/S transition of mitotic cell cycle
1.55	2.73e-12	GO:0071842	cellular component organization at cellular level
1.53	2.91e-12	GO:0071841	cellular component organization or biogenesis at cellular level
3.26	6.32e-12	GO:0071156	regulation of cell cycle arrest
3.93	7.58e-12	GO:0006333	chromatin assembly or disassembly
1.29	8.48e-12	GO:0044237	cellular metabolic process
3.27	2.02e-11	GO:0000075	cell cycle checkpoint
1.44	3.38e-11	GO:0016043	cellular component organization
1.43	9.36e-11	GO:0071840	cellular component organization or biogenesis
2.84	9.57e-11	GO:0000280	nuclear division
2.84	9.57e-11	GO:0007067	mitosis
5.12	1.78e-10	GO:0006261	DNA-dependent DNA replication
1.14	1.88e-10	GO:0009987	cellular process
2.76	3.73e-10	GO:0000087	M phase of mitotic cell cycle
2.75	4.40e-10	GO:0048285	organelle fission
4.08	4.52e-10	GO:0051320	S phase
1.26	7.55e-10	GO:0044238	primary metabolic process
4.03	1.42e-09	GO:0000084	S phase of mitotic cell cycle
2.52	2.39e-09	GO:0034622	cellular macromolecular complex assembly
3.61	3.13e-09	GO:0006310	DNA recombination
1.61	1.75e-08	GO:0034645	cellular macromolecule biosynthetic process
1.91	2.16e-08	GO:0033554	cellular response to stress
7.32	4.94e-08	GO:0006271	DNA strand elongation involved in DNA replication
1.59	5.03e-08	GO:0009059	macromolecule biosynthetic process
1.58	6.63e-08	GO:0016070	RNA metabolic process
1.97	8.71e-08	GO:0065003	macromolecular complex assembly
1.21	8.78e-08	GO:0008152	metabolic process
6.83	2.03e-07	GO:0022616	DNA strand elongation
2.15	2.46e-07	GO:0034621	cellular macromolecular complex subunit organization
8.33	4.07e-07	GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle
2.07	6.13e-07	GO:0016071	mRNA metabolic process
1.36	7.54e-07	GO:0060255	regulation of macromolecule metabolic process
1.68	7.68e-07	GO:0044085	cellular component biogenesis
1.34	1.15e-06	GO:0031323	regulation of cellular metabolic process
1.34	1.90e-06	GO:0080090	regulation of primary metabolic process
1.70	1.99e-06	GO:0022607	cellular component assembly
2.31	2.13e-06	GO:0051301	cell division
1.80	2.15e-06	GO:0043933	macromolecular complex subunit organization
1.43	2.73e-06	GO:0044249	cellular biosynthetic process
3.41	6.12e-06	GO:0007126	meiosis
3.41	6.12e-06	GO:0051327	M phase of meiotic cell cycle
1.38	7.27e-06	GO:0051171	regulation of nitrogen compound metabolic process
3.38	7.71e-06	GO:0051321	meiotic cell cycle
4.77	7.80e-06	GO:0051053	negative regulation of DNA metabolic process
3.45	8.61e-06	GO:0007059	chromosome segregation
1.38	1.42e-05	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38	1.42e-05	GO:0031326	regulation of cellular biosynthetic process
1.81	1.45e-05	GO:0071844	cellular component assembly at cellular level
1.39	1.57e-05	GO:0009058	biosynthetic process
1.40	1.95e-05	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.29	2.33e-05	GO:0019222	regulation of metabolic process
1.47	2.45e-05	GO:0010467	gene expression
1.37	2.64e-05	GO:0009889	regulation of biosynthetic process
7.83	2.85e-05	GO:0007062	sister chromatid cohesion
3.78	3.27e-05	GO:0000216	M/G1 transition of mitotic cell cycle
6.99	3.56e-05	GO:0006270	DNA-dependent DNA replication initiation
1.88	3.64e-05	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.38	5.24e-05	GO:0010556	regulation of macromolecule biosynthetic process
2.15	5.75e-05	GO:0016568	chromatin modification
2.11	6.17e-05	GO:0006397	mRNA processing
1.86	6.43e-05	GO:0051172	negative regulation of nitrogen compound metabolic process
6.68	6.92e-05	GO:0090329	regulation of DNA-dependent DNA replication
7.05	1.30e-04	GO:2000104	negative regulation of DNA-dependent DNA replication
5.06	1.45e-04	GO:0008156	negative regulation of DNA replication
1.39	1.55e-04	GO:0051252	regulation of RNA metabolic process
1.36	1.95e-04	GO:0010468	regulation of gene expression
1.66	2.42e-04	GO:0010605	negative regulation of macromolecule metabolic process
4.12	2.87e-04	GO:0007127	meiosis I
4.56	2.96e-04	GO:0000819	sister chromatid segregation
1.62	3.56e-04	GO:0009892	negative regulation of metabolic process
1.38	4.05e-04	GO:0006355	regulation of transcription, DNA-dependent
1.78	4.07e-04	GO:0006396	RNA processing
2.17	5.14e-04	GO:0008380	RNA splicing
4.58	6.89e-04	GO:0000070	mitotic sister chromatid segregation
2.47	7.55e-04	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.47	7.55e-04	GO:0000398	nuclear mRNA splicing, via spliceosome
3.51	1.09e-03	GO:0006338	chromatin remodeling
5.87	1.44e-03	GO:0031055	chromatin remodeling at centromere
2.40	1.48e-03	GO:0000375	RNA splicing, via transesterification reactions
1.76	1.55e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
4.90	1.74e-03	GO:0000080	G1 phase of mitotic cell cycle
5.12	2.65e-03	GO:0007131	reciprocal meiotic recombination
1.60	2.71e-03	GO:0031324	negative regulation of cellular metabolic process
1.69	3.48e-03	GO:0031327	negative regulation of cellular biosynthetic process
2.83	3.49e-03	GO:0031570	DNA integrity checkpoint
2.55	3.64e-03	GO:0000226	microtubule cytoskeleton organization
1.70	4.70e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.15	5.09e-03	GO:0050794	regulation of cellular process
2.60	5.24e-03	GO:0051052	regulation of DNA metabolic process
4.50	5.36e-03	GO:0051318	G1 phase
1.35	5.51e-03	GO:0048523	negative regulation of cellular process
1.32	6.92e-03	GO:0048519	negative regulation of biological process
1.66	7.96e-03	GO:0009890	negative regulation of biosynthetic process
2.71	8.06e-03	GO:0050657	nucleic acid transport
2.71	8.06e-03	GO:0050658	RNA transport
2.71	8.06e-03	GO:0051236	establishment of RNA localization
5.03	9.30e-03	GO:0043044	ATP-dependent chromatin remodeling
3.29	1.10e-02	GO:0006302	double-strand break repair
6.07	1.14e-02	GO:0032201	telomere maintenance via semi-conservative replication
1.53	1.33e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter
9.61	1.34e-02	GO:0007064	mitotic sister chromatid cohesion
2.07	1.41e-02	GO:0007346	regulation of mitotic cell cycle
2.63	1.51e-02	GO:0006403	RNA localization
1.14	1.62e-02	GO:0050789	regulation of biological process
2.73	1.80e-02	GO:0051028	mRNA transport
5.77	1.93e-02	GO:0000722	telomere maintenance via recombination
3.04	2.13e-02	GO:0006275	regulation of DNA replication
5.12	2.15e-02	GO:0043486	histone exchange
1.88	2.79e-02	GO:0007420	brain development
4.93	3.25e-02	GO:0006312	mitotic recombination
3.66	3.44e-02	GO:0007051	spindle organization
3.66	3.44e-02	GO:0032200	telomere organization
8.54	3.76e-02	GO:0002566	somatic diversification of immune receptors via somatic mutation
8.54	3.76e-02	GO:0016446	somatic hypermutation of immunoglobulin genes
4.40	4.18e-02	GO:0000724	double-strand break repair via homologous recombination
4.40	4.18e-02	GO:0000725	recombinational repair
2.43	4.23e-02	GO:0015931	nucleobase, nucleoside, nucleotide and nucleic acid transport
1.53	4.47e-02	GO:0006351	transcription, DNA-dependent
5.24	4.95e-02	GO:0006336	DNA replication-independent nucleosome assembly
5.24	4.95e-02	GO:0034080	CenH3-containing nucleosome assembly at centromere
5.24	4.95e-02	GO:0034724	DNA replication-independent nucleosome organization

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.60	7.67e-47	GO:0005634	nucleus
1.31	2.88e-40	GO:0043226	organelle
1.31	5.91e-40	GO:0043229	intracellular organelle
2.05	5.26e-38	GO:0044428	nuclear part
1.34	1.46e-37	GO:0043227	membrane-bounded organelle
1.34	1.89e-37	GO:0043231	intracellular membrane-bounded organelle
2.09	1.77e-33	GO:0031981	nuclear lumen
1.23	3.55e-33	GO:0044424	intracellular part
3.20	1.82e-32	GO:0005694	chromosome
1.21	1.68e-31	GO:0005622	intracellular
1.48	1.18e-30	GO:0044446	intracellular organelle part
1.92	1.23e-30	GO:0070013	intracellular organelle lumen
1.89	9.74e-30	GO:0043233	organelle lumen
1.88	1.63e-29	GO:0031974	membrane-enclosed lumen
1.47	2.61e-29	GO:0044422	organelle part
2.20	1.42e-27	GO:0005654	nucleoplasm
3.21	4.94e-27	GO:0044427	chromosomal part
3.57	8.50e-18	GO:0000785	chromatin
1.59	3.92e-17	GO:0043228	non-membrane-bounded organelle
1.59	3.92e-17	GO:0043232	intracellular non-membrane-bounded organelle
1.47	7.60e-15	GO:0032991	macromolecular complex
3.17	1.24e-11	GO:0000228	nuclear chromosome
3.32	2.30e-10	GO:0044454	nuclear chromosome part
2.01	5.03e-10	GO:0044451	nucleoplasm part
4.09	1.64e-09	GO:0032993	protein-DNA complex
4.34	1.49e-06	GO:0000786	nucleosome
1.35	1.73e-06	GO:0043234	protein complex
2.56	1.91e-06	GO:0016604	nuclear body
1.05	2.95e-06	GO:0044464	cell part
1.05	3.06e-06	GO:0005623	cell
2.96	4.29e-06	GO:0000775	chromosome, centromeric region
5.19	1.63e-05	GO:0005657	replication fork
4.66	3.53e-05	GO:0000792	heterochromatin
11.21	5.43e-05	GO:0042555	MCM complex
2.75	1.14e-04	GO:0000793	condensed chromosome
1.83	1.84e-04	GO:0030529	ribonucleoprotein complex
9.96	2.28e-04	GO:0005721	centromeric heterochromatin
3.28	3.31e-04	GO:0000790	nuclear chromatin
2.41	4.96e-04	GO:0005819	spindle
1.67	7.35e-04	GO:0015630	microtubule cytoskeleton
6.41	1.10e-03	GO:0030530	heterogeneous nuclear ribonucleoprotein complex
1.95	1.31e-03	GO:0005815	microtubule organizing center
2.15	2.93e-03	GO:0005813	centrosome
1.71	5.39e-03	GO:0005730	nucleolus
6.03	7.23e-03	GO:0030894	replisome
6.03	7.23e-03	GO:0043601	nuclear replisome
5.24	8.50e-03	GO:0043596	nuclear replication fork
6.41	1.54e-02	GO:0001673	male germ cell nucleus
1.54	2.03e-02	GO:0031967	organelle envelope
1.53	2.20e-02	GO:0031975	envelope
5.61	4.46e-02	GO:0043073	germ cell nucleus

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.65	4.57e-26	GO:0003676	nucleic acid binding
1.71	1.40e-19	GO:0003677	DNA binding
1.26	1.64e-13	GO:0005515	protein binding
1.13	2.72e-12	GO:0005488	binding
4.27	1.61e-05	GO:0003697	single-stranded DNA binding
2.60	1.97e-05	GO:0003682	chromatin binding
2.56	4.60e-05	GO:0043566	structure-specific DNA binding
1.36	9.00e-05	GO:0000166	nucleotide binding
1.66	1.26e-04	GO:0003723	RNA binding
3.80	1.30e-04	GO:0008094	DNA-dependent ATPase activity
4.27	2.03e-04	GO:0003684	damaged DNA binding
1.55	6.15e-04	GO:0030528	transcription regulator activity
1.55	7.13e-04	GO:0001071	nucleic acid binding transcription factor activity
1.55	7.13e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
2.47	7.92e-03	GO:0003690	double-stranded DNA binding
6.41	2.20e-02	GO:0030983	mismatched DNA binding
1.35	3.17e-02	GO:0032559	adenyl ribonucleotide binding
1.34	4.18e-02	GO:0030554	adenyl nucleotide binding