Motif ID: ESRRA.p2

Z-value: 2.986


Transcription factors associated with ESRRA.p2:

Gene SymbolEntrez IDGene Name
ESRRA 2101 estrogen-related receptor alpha

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
ESRRAchr11_+_638296160.758.6e-04Click!


Activity profile for motif ESRRA.p2.

activity profile for motif ESRRA.p2


Sorted Z-values histogram for motif ESRRA.p2

Sorted Z-values for motif ESRRA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESRRA.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_143706265 7.487 PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_143706196 5.705 PDE4DIP
phosphodiesterase 4D interacting protein
chr19_-_44518465 4.869 GMFG
glia maturation factor, gamma
chr20_+_36867708 4.381 NM_001172735
NM_015568
 PPP1R16B

protein phosphatase 1, regulatory (inhibitor) subunit 16B

chr19_-_44518516 4.277 NM_004877
 GMFG
glia maturation factor, gamma
chr2_+_119905812 4.187 NM_183240
 TMEM37
transmembrane protein 37
chr19_+_17923110 3.543 NM_002248
 KCNN1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr12_-_52980914 3.458 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr22_-_22440054 3.431 NM_213720
 CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr12_-_52980984 3.417 NM_001136023
 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr11_-_64268841 3.289 NM_001098670
 RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr5_-_1647617 3.275 SDHAP3
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3
chr6_+_34314545 3.259 NM_145905
 HMGA1
high mobility group AT-hook 1
chr19_-_4486202 3.189 NM_001013706
 PLIN5
perilipin 5
chr6_+_44076281 2.931 NM_001171992
NM_153246
 C6orf223

chromosome 6 open reading frame 223

chr22_+_18485145 2.905 RANBP1
RAN binding protein 1
chr10_-_91394881 2.801 PANK1
pantothenate kinase 1
chr15_-_89276657 2.767 NM_198527
 HDDC3
HD domain containing 3
chr4_-_40212670 2.732 NM_019027
 RBM47
RNA binding motif protein 47
chr2_+_219453487 2.708 NM_025216
 WNT10A
wingless-type MMTV integration site family, member 10A

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
6.12 3.84e-06 GO:0042773 ATP synthesis coupled electron transport
6.12 3.84e-06 GO:0042775 mitochondrial ATP synthesis coupled electron transport
6.08 1.42e-04 GO:0006120 mitochondrial electron transport, NADH to ubiquinone
5.84 2.78e-06 GO:0006119 oxidative phosphorylation
5.13 5.50e-10 GO:0022904 respiratory electron transport chain
4.56 1.79e-10 GO:0045333 cellular respiration
4.08 2.41e-08 GO:0022900 electron transport chain
3.46 2.35e-02 GO:0006839 mitochondrial transport
2.97 8.24e-08 GO:0015980 energy derivation by oxidation of organic compounds
2.65 2.54e-08 GO:0006091 generation of precursor metabolites and energy
2.61 1.38e-02 GO:0006732 coenzyme metabolic process
2.33 2.84e-02 GO:0051186 cofactor metabolic process
2.02 2.13e-08 GO:0055114 oxidation-reduction process
1.37 7.12e-04 GO:0006810 transport
1.35 2.24e-03 GO:0051234 establishment of localization

Gene overrepresentation in compartment category:

Showing 1 to 17 of 17 entries
enrichment   p-value GO term description
5.61 7.41e-05 GO:0005747 mitochondrial respiratory chain complex I
5.61 7.41e-05 GO:0030964 NADH dehydrogenase complex
5.61 7.41e-05 GO:0045271 respiratory chain complex I
4.85 1.87e-06 GO:0070469 respiratory chain
4.69 2.04e-05 GO:0005746 mitochondrial respiratory chain
4.28 1.08e-09 GO:0044455 mitochondrial membrane part
3.65 5.93e-18 GO:0005743 mitochondrial inner membrane
3.45 3.66e-17 GO:0019866 organelle inner membrane
3.13 1.16e-17 GO:0031966 mitochondrial membrane
3.07 1.27e-17 GO:0005740 mitochondrial envelope
2.71 1.52e-18 GO:0044429 mitochondrial part
2.30 5.18e-12 GO:0031975 envelope
2.29 1.27e-11 GO:0031967 organelle envelope
2.11 1.41e-17 GO:0005739 mitochondrion
2.08 3.27e-02 GO:0005759 mitochondrial matrix
1.25 4.62e-06 GO:0044444 cytoplasmic part
1.17 8.34e-05 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 15 of 15 entries
enrichment   p-value GO term description
5.61 2.76e-02 GO:0004129 cytochrome-c oxidase activity
5.61 2.76e-02 GO:0015002 heme-copper terminal oxidase activity
5.61 2.76e-02 GO:0016675 oxidoreductase activity, acting on a heme group of donors
5.61 2.76e-02 GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
5.46 4.90e-04 GO:0003954 NADH dehydrogenase activity
5.46 4.90e-04 GO:0008137 NADH dehydrogenase (ubiquinone) activity
5.46 4.90e-04 GO:0050136 NADH dehydrogenase (quinone) activity
5.09 4.27e-04 GO:0016655 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
3.40 6.99e-04 GO:0015078 hydrogen ion transmembrane transporter activity
2.38 2.00e-02 GO:0015077 monovalent inorganic cation transmembrane transporter activity
2.29 5.69e-03 GO:0022890 inorganic cation transmembrane transporter activity
1.89 3.08e-05 GO:0016491 oxidoreductase activity
1.62 3.40e-02 GO:0015075 ion transmembrane transporter activity
1.57 3.16e-02 GO:0022891 substrate-specific transmembrane transporter activity
1.20 7.64e-03 GO:0003824 catalytic activity