Motif ID: NKX3-1.p2

Z-value: 1.110


Transcription factors associated with NKX3-1.p2:

Gene SymbolEntrez IDGene Name
NKX3-1 4824 NK3 homeobox 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NKX3-1chr8_-_23596346-0.048.8e-01Click!


Activity profile for motif NKX3-1.p2.

activity profile for motif NKX3-1.p2


Sorted Z-values histogram for motif NKX3-1.p2

Sorted Z-values for motif NKX3-1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NKX3-1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_132000134 3.876 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr17_-_61655915 1.752 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr17_-_18890963 1.428 NM_006613
GRAP
GRB2-related adaptor protein
chr4_+_74520796 1.319 NM_001134
AFP
alpha-fetoprotein
chr12_+_130004404 1.126 NM_198827
GPR133
G protein-coupled receptor 133
chr19_-_56612653 1.101 NM_001171156
NM_001171157
NM_001171158
NM_001171159
NM_001171160
NM_001171161
NM_033130
SIGLEC10






sialic acid binding Ig-like lectin 10






chr4_+_74488947 1.065 ALB
albumin
chr6_+_30238961 1.051 NM_033229
TRIM15
tripartite motif containing 15
chr14_-_22516271 1.043 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr2_+_228064531 0.985 AGFG1
ArfGAP with FG repeats 1
chr15_+_57691382 0.981 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr5_+_156628929 0.966 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr4_+_74491272 0.965 ALB
albumin
chr3_-_198784590 0.956 NM_203315
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr14_+_38772870 0.913 NM_054024
MIA2
melanoma inhibitory activity 2
chr14_+_87541220 0.899 NM_003608
GPR65
G protein-coupled receptor 65
chr17_-_53847937 0.888 RNF43
ring finger protein 43
chr6_+_32003180 0.850 NM_000063
NM_001145903
C2

complement component 2

chr2_-_32344192 0.849 NM_021209
NLRC4
NLR family, CARD domain containing 4
chr1_+_205329206 0.821 NM_000716
NM_001017364
NM_001017367
C4BPB


complement component 4 binding protein, beta



Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 7 of 7 entries
enrichment   p-value GO term description
3.77 2.97e-21 GO:0007608 sensory perception of smell
3.55 1.12e-20 GO:0007606 sensory perception of chemical stimulus
2.40 2.21e-12 GO:0007600 sensory perception
1.87 1.87e-08 GO:0050877 neurological system process
1.79 2.65e-09 GO:0003008 system process
1.33 2.16e-06 GO:0032501 multicellular organismal process
1.26 3.64e-05 GO:0050896 response to stimulus

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
1.43 1.42e-03 GO:0005576 extracellular region
1.38 1.42e-07 GO:0005886 plasma membrane
1.38 1.61e-07 GO:0071944 cell periphery
1.22 2.19e-03 GO:0031224 intrinsic to membrane
1.22 2.66e-03 GO:0016021 integral to membrane
1.18 1.08e-02 GO:0044425 membrane part

Gene overrepresentation in function category:

Showing 1 to 9 of 9 entries
enrichment   p-value GO term description
8.84 1.21e-02 GO:0004522 pancreatic ribonuclease activity
7.18 4.94e-02 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters
6.38 3.07e-02 GO:0016894 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters
3.85 7.59e-22 GO:0004984 olfactory receptor activity
2.56 1.33e-16 GO:0004930 G-protein coupled receptor activity
2.01 1.11e-11 GO:0004888 transmembrane receptor activity
1.79 4.72e-10 GO:0004872 receptor activity
1.62 6.78e-08 GO:0004871 signal transducer activity
1.62 6.78e-08 GO:0060089 molecular transducer activity