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Motif ID: NKX3-1.p2

Z-value: 1.110

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_+_132000134	3.876	NM_005021	ENPP3	ectonucleotide pyrophosphatase/phosphodiesterase 3
chr17_-_61655915	1.752	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr17_-_18890963	1.428	NM_006613	GRAP	GRB2-related adaptor protein
chr4_+_74520796	1.319	NM_001134	AFP	alpha-fetoprotein
chr12_+_130004404	1.126	NM_198827	GPR133	G protein-coupled receptor 133
chr19_-_56612653	1.101	NM_001171156 NM_001171157 NM_001171158 NM_001171159 NM_001171160 NM_001171161 NM_033130	SIGLEC10	sialic acid binding Ig-like lectin 10
chr4_+_74488947	1.065		ALB	albumin
chr6_+_30238961	1.051	NM_033229	TRIM15	tripartite motif containing 15
chr14_-_22516271	1.043	NM_198086	JUB	jub, ajuba homolog (Xenopus laevis)
chr2_+_228064531	0.985		AGFG1	ArfGAP with FG repeats 1
chr15_+_57691382	0.981		GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr5_+_156628929	0.966	NM_014376	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr4_+_74491272	0.965		ALB	albumin
chr3_-_198784590	0.956	NM_203315	BDH1	3-hydroxybutyrate dehydrogenase, type 1
chr14_+_38772870	0.913	NM_054024	MIA2	melanoma inhibitory activity 2
chr14_+_87541220	0.899	NM_003608	GPR65	G protein-coupled receptor 65
chr17_-_53847937	0.888		RNF43	ring finger protein 43
chr6_+_32003180	0.850	NM_000063 NM_001145903	C2	complement component 2
chr2_-_32344192	0.849	NM_021209	NLRC4	NLR family, CARD domain containing 4
chr1_+_205329206	0.821	NM_000716 NM_001017364 NM_001017367	C4BPB	complement component 4 binding protein, beta
chr17_-_16197433	0.819	NM_181716	CENPV	centromere protein V
chr14_+_66901237	0.818		EIF2S1	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr2_+_37282516	0.817		LOC100505876	hypothetical LOC100505876
chr17_+_50698169	0.795		HLF	hepatic leukemia factor
chr1_+_57093030	0.781	NM_000562	C8A	complement component 8, alpha polypeptide
chr22_+_38652555	0.761		GRAP2	GRB2-related adaptor protein 2
chr12_-_101835510	0.748	NM_000277	PAH	phenylalanine hydroxylase
chr4_-_186969041	0.746	NM_001145672	SORBS2	sorbin and SH3 domain containing 2
chr10_-_74384485	0.737	NM_032562	PLA2G12B	phospholipase A2, group XIIB
chr6_+_153060722	0.732	NM_025107	MYCT1	myc target 1
chr12_-_120725210	0.731		LOC338799	hypothetical LOC338799
chr3_-_42892195	0.725		CYP8B1	cytochrome P450, family 8, subfamily B, polypeptide 1
chr4_+_74493918	0.703		ALB	albumin
chr13_+_23042722	0.694	NM_148957	TNFRSF19	tumor necrosis factor receptor superfamily, member 19
chr5_+_43645018	0.691		NNT	nicotinamide nucleotide transhydrogenase
chr15_+_57691272	0.689	NM_004751	GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr3_+_152970904	0.685		LOC201651	arylacetamide deacetylase (esterase) pseudogene
chr3_+_173043832	0.684	NM_001164436	TMEM212	transmembrane protein 212
chr4_+_39084936	0.671		KLB	klotho beta
chrX_+_105823723	0.663	NM_024539	RNF128	ring finger protein 128
chr2_-_165259334	0.660		COBLL1	COBL-like 1
chr8_+_40130143	0.655	NM_020130	C8orf4	chromosome 8 open reading frame 4
chr12_+_91620749	0.647	NM_001037671 NM_001178097	C12orf74	chromosome 12 open reading frame 74
chr4_+_74488835	0.643	NM_000477	ALB	albumin
chr9_+_89302574	0.635	NM_004938	DAPK1	death-associated protein kinase 1
chr8_-_17797127	0.618	NM_147203 NM_201553 NM_004467 NM_201552	FGL1	fibrinogen-like 1
chr10_-_11614279	0.603	NM_001080491	USP6NL	USP6 N-terminal like
chr18_+_70318001	0.592		CNDP2	CNDP dipeptidase 2 (metallopeptidase M20 family)
chr18_-_50776276	0.583	NM_001143829	CCDC68	coiled-coil domain containing 68
chr20_+_30160952	0.573	NM_014742	TM9SF4	transmembrane 9 superfamily protein member 4
chr11_+_89507465	0.570	NM_005467	NAALAD2	N-acetylated alpha-linked acidic dipeptidase 2
chr6_+_64344307	0.562		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chrX_-_130792297	0.559		LOC286467	hypothetical LOC286467
chr9_-_103237851	0.552	NM_000035	ALDOB	aldolase B, fructose-bisphosphate
chr6_+_32003380	0.548		C2	complement component 2
chr5_-_78317444	0.543	NM_198709	ARSB	arylsulfatase B
chr17_-_16197549	0.527		CENPV	centromere protein V
chr9_+_89302239	0.525		DAPK1	death-associated protein kinase 1
chr10_-_73953699	0.524	NM_001195519	CBARA1	calcium binding atopy-related autoantigen 1
chr10_-_69267774	0.524	NM_021800 NM_201262	DNAJC12	DnaJ (Hsp40) homolog, subfamily C, member 12
chr17_+_35097851	0.524	NM_001005862	ERBB2	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
chr20_+_30161173	0.512		TM9SF4	transmembrane 9 superfamily protein member 4
chr6_-_32268615	0.503		GPSM3	G-protein signaling modulator 3
chr3_-_121883647	0.502		HGD	homogentisate 1,2-dioxygenase
chr5_-_179040580	0.499	NM_001164444	CBY3	chibby homolog 3 (Drosophila)
chrX_+_99726445	0.498	NM_022144	TNMD	tenomodulin
chr4_+_89115862	0.498		SPP1	secreted phosphoprotein 1
chr19_-_56549853	0.495	NM_001014763	ETFB	electron-transfer-flavoprotein, beta polypeptide
chr17_-_64752550	0.480	NM_080282	ABCA10	ATP-binding cassette, sub-family A (ABC1), member 10
chr12_+_25096472	0.476	NM_006152	LRMP	lymphoid-restricted membrane protein
chr2_+_183290912	0.474		DNAJC10	DnaJ (Hsp40) homolog, subfamily C, member 10
chr7_+_94377145	0.471	NM_001166161 NM_001166162 NM_001166163	PPP1R9A	protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr14_-_22515725	0.471		JUB	jub, ajuba homolog (Xenopus laevis)
chr1_-_229627412	0.468	NM_022051	EGLN1	egl nine homolog 1 (C. elegans)
chr6_+_27885692	0.468	NM_003536	HIST1H3H	histone cluster 1, H3h
chr17_-_36113502	0.455	NM_019016	KRT24	keratin 24
chr18_+_27210737	0.454	NM_001134453 NM_177986	DSG4	desmoglein 4
chr5_+_140709907	0.451	NM_018922 NM_032095	PCDHGB1	protocadherin gamma subfamily B, 1
chr20_-_52120710	0.450	NM_003657	BCAS1	breast carcinoma amplified sequence 1
chr17_+_58440629	0.447	NM_025185	TANC2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr4_-_69852090	0.445	NM_024743	UGT2A3	UDP glucuronosyltransferase 2 family, polypeptide A3
chr1_+_165565006	0.444		POU2F1	POU class 2 homeobox 1
chr4_+_17125885	0.443	NM_001079827	CLRN2	clarin 2
chr17_+_71975224	0.442	NM_001088	AANAT	aralkylamine N-acetyltransferase
chr3_-_152403636	0.441	NM_013308	GPR171	G protein-coupled receptor 171
chr6_+_153113624	0.440	NM_003381 NM_194435	VIP	vasoactive intestinal peptide
chr6_-_33016561	0.440	NM_002118	HLA-DMB	major histocompatibility complex, class II, DM beta
chr14_+_94148466	0.432	NM_001085	SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr6_-_28294642	0.428		LOC222699	transducer of ERBB2, 2 pseudogene
chr4_+_74488910	0.425		ALB	albumin
chr1_-_158815850	0.423		CD84	CD84 molecule
chr14_+_31868229	0.422	NM_004274	AKAP6	A kinase (PRKA) anchor protein 6
chr20_-_34707971	0.419	NM_032214 NM_175077	SLA2	Src-like-adaptor 2
chr4_+_89115892	0.418		SPP1	secreted phosphoprotein 1
chr3_-_57209319	0.415	NM_003865	HESX1	HESX homeobox 1
chr3_-_195553297	0.413	NM_001080513	CPN2	carboxypeptidase N, polypeptide 2
chr14_-_24115268	0.408	NM_001911	CTSG	cathepsin G
chr6_+_28425666	0.402	NM_024493	ZKSCAN3	zinc finger with KRAB and SCAN domains 3
chr4_+_1872150	0.397	NM_133334	WHSC1	Wolf-Hirschhorn syndrome candidate 1
chr4_+_89115923	0.397		SPP1	secreted phosphoprotein 1
chr6_-_138862271	0.396	NM_001144060	NHSL1	NHS-like 1
chr7_+_141457977	0.395		LOC93432	maltase-glucoamylase-like pseudogene
chr4_-_10295412	0.389	NM_052964	CLNK	cytokine-dependent hematopoietic cell linker
chr7_+_99654806	0.389	NM_024070	PVRIG	poliovirus receptor related immunoglobulin domain containing
chr6_-_49712483	0.387	NM_000324	RHAG	Rh-associated glycoprotein
chr1_-_205012348	0.387	NM_000572	IL10	interleukin 10
chr4_+_89115825	0.386	NM_000582 NM_001040058 NM_001040060	SPP1	secreted phosphoprotein 1
chr4_-_140280031	0.381	NM_201999	ELF2	E74-like factor 2 (ets domain transcription factor)
chr22_+_29696662	0.381
chr10_+_101078784	0.371	NM_020348	CNNM1	cyclin M1
chr21_+_39117064	0.371		ETS2	v-ets erythroblastosis virus E26 oncogene homolog 2 (avian)
chr9_+_4829763	0.369		RCL1	RNA terminal phosphate cyclase-like 1
chr2_-_39310176	0.369	NM_001009565	CDKL4	cyclin-dependent kinase-like 4
chr6_-_138862273	0.368
chr14_+_22859236	0.367	NM_004643	PABPN1	poly(A) binding protein, nuclear 1
chr7_-_143213296	0.365		FAM115A	family with sequence similarity 115, member A
chr4_-_68793928	0.363	NM_182502	TMPRSS11B	transmembrane protease, serine 11B
chr12_-_15757114	0.362		EPS8	epidermal growth factor receptor pathway substrate 8
chr3_-_120761092	0.352	NM_005191	CD80	CD80 molecule
chr2_+_42649105	0.348	NM_020744	MTA3	metastasis associated 1 family, member 3
chr2_-_21106291	0.347		APOB	apolipoprotein B (including Ag(x) antigen)
chr1_-_246869181	0.346	NM_001001827	OR2T35	olfactory receptor, family 2, subfamily T, member 35
chr10_-_7722747	0.345		ITIH5	inter-alpha (globulin) inhibitor H5
chr6_+_105511615	0.345	NM_001004317	LIN28B	lin-28 homolog B (C. elegans)
chr16_+_80626331	0.344	NM_002153	HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr13_+_51496679	0.343	NM_021645	ALG11 UTP14C	asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast) UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr16_+_80626459	0.342		HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr4_-_38710376	0.339	NM_024943	TMEM156	transmembrane protein 156
chr2_-_99412694	0.338		REV1	REV1 homolog (S. cerevisiae)
chr4_-_176970407	0.335		GPM6A	glycoprotein M6A
chr7_+_119700924	0.334	NM_012281	KCND2	potassium voltage-gated channel, Shal-related subfamily, member 2
chr8_-_82557956	0.334	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr1_+_103898844	0.328	NM_020978	AMY2B	amylase, alpha 2B (pancreatic)
chr5_+_92944680	0.327	NM_005654	NR2F1	nuclear receptor subfamily 2, group F, member 1
chrX_+_57329834	0.326	NM_174912	FAAH2	fatty acid amide hydrolase 2
chr9_-_13240313	0.326	NM_003829	MPDZ	multiple PDZ domain protein
chr21_-_42659671	0.326	NM_003225	TFF1	trefoil factor 1
chr2_+_102744921	0.325	NM_144632	TMEM182	transmembrane protein 182
chr11_-_100505667	0.323	NM_000926	PGR	progesterone receptor
chr16_+_2195424	0.322	NM_022372	MLST8	MTOR associated protein, LST8 homolog (S. cerevisiae)
chr6_-_152681171	0.321	NM_015293	SYNE1	spectrin repeat containing, nuclear envelope 1
chr6_+_144654565	0.320	NM_007124	UTRN	utrophin
chrX_-_30505804	0.319	NM_025159	CXorf21	chromosome X open reading frame 21
chr16_+_82540172	0.316	NM_013370 NM_182980	OSGIN1	oxidative stress induced growth inhibitor 1
chr11_+_89624017	0.315
chr3_-_150569574	0.315		TM4SF1	transmembrane 4 L six family member 1
chrX_-_2892288	0.312	NM_000047	ARSE	arylsulfatase E (chondrodysplasia punctata 1)
chrX_-_76824726	0.310		ATRX	alpha thalassemia/mental retardation syndrome X-linked
chr14_-_24148658	0.310	NM_033423	GZMH	granzyme H (cathepsin G-like 2, protein h-CCPX)
chr3_-_184756101	0.309	NM_130446	KLHL6	kelch-like 6 (Drosophila)
chr17_-_16816113	0.306	NM_012452	TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B
chr4_+_71418886	0.304	NM_212557	AMTN	amelotin
chr10_+_7785360	0.298		ITIH2	inter-alpha (globulin) inhibitor H2
chr2_+_173394560	0.298	NM_001100397	RAPGEF4	Rap guanine nucleotide exchange factor (GEF) 4
chr1_-_158815895	0.296	NM_001184879 NM_001184881 NM_001184882 NM_003874	CD84	CD84 molecule
chr19_+_63508569	0.296		LOC100506584	hypothetical protein LOC100506584
chr15_+_97990705	0.295	NM_001130928	MEF2A	myocyte enhancer factor 2A
chr9_+_130056513	0.295
chr2_-_207291364	0.294	NM_001093730	DYTN	dystrotelin
chr17_-_39500512	0.293	NM_152344	LSM12	LSM12 homolog (S. cerevisiae)
chr20_+_60191455	0.292	NM_015666	GTPBP5	GTP binding protein 5 (putative)
chr1_+_66230977	0.285	NM_001037340	PDE4B	phosphodiesterase 4B, cAMP-specific
chr6_+_167445284	0.282	NM_004367	CCR6	chemokine (C-C motif) receptor 6
chr3_-_168853982	0.281	NM_178824	WDR49	WD repeat domain 49
chr9_+_106496480	0.280	NM_001004484	OR13D1	olfactory receptor, family 13, subfamily D, member 1
chr7_+_104468614	0.279		MLL5	myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr1_+_246682699	0.278	NM_001004136	OR2T2	olfactory receptor, family 2, subfamily T, member 2
chr16_+_80626402	0.275		HSD17B2	hydroxysteroid (17-beta) dehydrogenase 2
chr8_-_37576515	0.272		LOC157860	hypothetical protein LOC157860
chr1_+_158975662	0.270	NM_021181	SLAMF7	SLAM family member 7
chr4_+_74498042	0.270		ALB	albumin
chr3_-_42892636	0.270	NM_004391	CYP8B1	cytochrome P450, family 8, subfamily B, polypeptide 1
chr17_-_64568641	0.270	NM_080283	ABCA9	ATP-binding cassette, sub-family A (ABC1), member 9
chr11_-_30910074	0.270	NM_020869	DCDC5	doublecortin domain containing 5
chr20_+_56919233	0.269		GNAS	GNAS complex locus
chr16_+_11346812	0.269		C16orf75	chromosome 16 open reading frame 75
chr11_-_16953135	0.268		RPL36A	ribosomal protein L36a
chr1_+_50348052	0.266		ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr16_-_68317868	0.266		NQO1	NAD(P)H dehydrogenase, quinone 1
chr3_+_120799411	0.265	NM_015900	PLA1A	phospholipase A1 member A
chr4_+_71283383	0.265	NM_006685	SMR3B	submaxillary gland androgen regulated protein 3B
chr19_+_63508526	0.263		LOC100506584	hypothetical protein LOC100506584
chr4_-_176970372	0.262		GPM6A	glycoprotein M6A
chr6_-_55848317	0.262	NM_021073	BMP5	bone morphogenetic protein 5
chr4_+_74497998	0.261		ALB	albumin
chr2_+_201806410	0.261	NM_001080124 NM_001228 NM_033355 NM_033358	CASP8	caspase 8, apoptosis-related cysteine peptidase
chr17_-_5078773	0.258	NM_207103	C17orf87	chromosome 17 open reading frame 87
chrX_+_115215985	0.257	NM_000686	AGTR2	angiotensin II receptor, type 2
chrX_+_90977115	0.257	NM_001168360 NM_001168361 NM_001168362 NM_001168363	PCDH11X	protocadherin 11 X-linked
chr11_+_123625632	0.257	NM_001002905	OR8G1	olfactory receptor, family 8, subfamily G, member 1
chr17_+_24394043	0.253	NM_016518	PIPOX	pipecolic acid oxidase
chr9_-_94206648	0.253	NM_014057 NM_033014	OGN	osteoglycin
chr1_-_3556420	0.251	NM_017818	WDR8	WD repeat domain 8
chr3_+_162697289	0.251	NM_001080440	OTOL1	otolin 1 homolog (zebrafish)
chr17_+_23818922	0.249
chr10_-_52315436	0.248	NM_001198818 NM_001198819 NM_001198820 NM_014576 NM_138932 NM_138933	A1CF	APOBEC1 complementation factor
chr6_+_10629550	0.247	NM_145649	GCNT2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr5_+_67622242	0.246	NM_181504	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr10_+_7785290	0.245		ITIH2	inter-alpha (globulin) inhibitor H2
chr6_-_55848346	0.245		BMP5	bone morphogenetic protein 5

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
3.77	2.97e-21	GO:0007608	sensory perception of smell
3.55	1.12e-20	GO:0007606	sensory perception of chemical stimulus
2.40	2.21e-12	GO:0007600	sensory perception
1.79	2.65e-09	GO:0003008	system process
1.87	1.87e-08	GO:0050877	neurological system process
1.33	2.16e-06	GO:0032501	multicellular organismal process
1.26	3.64e-05	GO:0050896	response to stimulus

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.38	1.42e-07	GO:0005886	plasma membrane
1.38	1.61e-07	GO:0071944	cell periphery
1.43	1.42e-03	GO:0005576	extracellular region
1.22	2.19e-03	GO:0031224	intrinsic to membrane
1.22	2.66e-03	GO:0016021	integral to membrane
1.18	1.08e-02	GO:0044425	membrane part

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
3.85	7.59e-22	GO:0004984	olfactory receptor activity
2.56	1.33e-16	GO:0004930	G-protein coupled receptor activity
2.01	1.11e-11	GO:0004888	transmembrane receptor activity
1.79	4.72e-10	GO:0004872	receptor activity
1.62	6.78e-08	GO:0004871	signal transducer activity
1.62	6.78e-08	GO:0060089	molecular transducer activity
8.84	1.21e-02	GO:0004522	pancreatic ribonuclease activity
6.38	3.07e-02	GO:0016894	endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters
7.18	4.94e-02	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters