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• Activity deltas table
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Motif ID: PAX2.p2

Z-value: 1.041

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr5_+_60663842	1.990	NM_020928	ZSWIM6	zinc finger, SWIM-type containing 6
chr6_-_18230829	1.357	NM_198586	NHLRC1	NHL repeat containing 1
chr8_-_13178399	1.238		DLC1	deleted in liver cancer 1
chr10_+_128583984	1.066	NM_001380	DOCK1	dedicator of cytokinesis 1
chr8_-_13178327	1.025
chr13_-_32757835	0.966	NM_178006	STARD13	StAR-related lipid transfer (START) domain containing 13
chr2_-_192767494	0.957		TMEFF2	transmembrane protein with EGF-like and two follistatin-like domains 2
chr12_-_113330574	0.905	NM_000192 NM_080717	TBX5	T-box 5
chr2_-_216008689	0.890		FN1	fibronectin 1
chr10_+_102662675	0.882		FAM178A	family with sequence similarity 178, member A
chr17_+_14145051	0.867	NM_006041	HS3ST3B1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr15_-_68781662	0.861	NM_001008224	UACA	uveal autoantigen with coiled-coil domains and ankyrin repeats
chr3_+_114948550	0.859	NM_001690	ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr9_+_119506446	0.855		TLR4	toll-like receptor 4
chr1_-_197173159	0.850		LOC100131234	familial acute myelogenous leukemia related factor
chr13_-_20533703	0.837	NM_014572	LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)
chr10_+_102782151	0.835		SFXN3	sideroflexin 3
chr11_+_101485946	0.794	NM_001130145 NM_001195044 NM_006106	YAP1	Yes-associated protein 1
chr10_+_102782156	0.787		SFXN3	sideroflexin 3
chr9_-_37566248	0.772	NM_012166	FBXO10	F-box protein 10
chr9_-_109291866	0.748	NM_004235	KLF4	Kruppel-like factor 4 (gut)
chr7_-_27162688	0.747	NM_006896	HOXA7	homeobox A7
chr2_-_216009015	0.712	NM_002026 NM_054034 NM_212474 NM_212476 NM_212478 NM_212482	FN1	fibronectin 1
chr3_+_114948600	0.669		ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr2_-_216944911	0.669	NM_020814	MARCH4	membrane-associated ring finger (C3HC4) 4
chr2_+_223625105	0.662	NM_080671	KCNE4	potassium voltage-gated channel, Isk-related family, member 4
chr3_+_114948591	0.655		ATP6V1A	ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr6_+_17501589	0.654	NM_006366	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)
chr4_-_177950658	0.654	NM_005429	VEGFC	vascular endothelial growth factor C
chr3_+_30622905	0.649	NM_001024847 NM_003242	TGFBR2	transforming growth factor, beta receptor II (70/80kDa)
chr13_-_20533629	0.644		LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)
chr17_+_56831951	0.634	NM_005994	TBX2	T-box 2
chr7_+_116099648	0.631	NM_000245 NM_001127500	MET	met proto-oncogene (hepatocyte growth factor receptor)
chr12_+_15926554	0.629	NM_007178	STRAP	serine/threonine kinase receptor associated protein
chr1_-_152459667	0.629		C1orf43	chromosome 1 open reading frame 43
chr20_-_47965393	0.623		SPATA2	spermatogenesis associated 2
chr5_+_52812236	0.622	NM_006350 NM_013409	FST	follistatin
chr5_+_52812165	0.621		FST	follistatin
chr18_-_44729700	0.608	NM_001190822	SMAD7	SMAD family member 7
chr8_-_119192985	0.607	NM_000127	EXT1	exostosin 1
chr9_-_21999270	0.602	NM_004936 NM_078487	CDKN2B	cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr12_+_15926681	0.600		STRAP	serine/threonine kinase receptor associated protein
chr5_+_14493905	0.597		TRIO	triple functional domain (PTPRF interacting)
chr2_+_228045121	0.596	NM_001135187 NM_001135188 NM_001135189 NM_004504	AGFG1	ArfGAP with FG repeats 1
chr16_-_65984836	0.574	NM_015964 NM_016140	TPPP3	tubulin polymerization-promoting protein family member 3
chr14_+_95575319	0.572		C14orf132	chromosome 14 open reading frame 132
chr15_+_41597097	0.568	NM_002373	MAP1A	microtubule-associated protein 1A
chr21_-_27261276	0.558	NM_007038	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr10_-_93382735	0.536		PPP1R3C	protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr16_+_30952382	0.531	NM_004604	STX4	syntaxin 4
chr8_+_67787444	0.530	NM_001033578	SGK3	serum/glucocorticoid regulated kinase family, member 3
chr7_-_121571472	0.529	NM_005763	AASS	aminoadipate-semialdehyde synthase
chr1_+_181259317	0.524
chr10_-_93382779	0.519		PPP1R3C	protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr22_+_34107087	0.516		HMOX1	heme oxygenase (decycling) 1
chr1_+_77520190	0.513		AK5	adenylate kinase 5
chr14_+_23653848	0.511		DCAF11	DDB1 and CUL4 associated factor 11
chr16_+_56219802	0.511	NM_001145771 NM_001145772 NM_001145773 NM_201524 NM_201525	GPR56	G protein-coupled receptor 56
chr16_+_30952350	0.509		STX4	syntaxin 4
chr17_+_72795567	0.505	NM_001113492	SEPT9	septin 9
chr2_-_217267742	0.504		IGFBP5	insulin-like growth factor binding protein 5
chr16_-_69277355	0.503	NM_138383	MTSS1L	metastasis suppressor 1-like
chr14_+_23653745	0.503	NM_001163484	DCAF11	DDB1 and CUL4 associated factor 11
chr5_-_83715947	0.502		EDIL3	EGF-like repeats and discoidin I-like domains 3
chr5_+_80292313	0.500	NM_006909	RASGRF2	Ras protein-specific guanine nucleotide-releasing factor 2
chr11_+_101291134	0.499		KIAA1377	KIAA1377
chr12_+_15926743	0.498		STRAP	serine/threonine kinase receptor associated protein
chr1_-_152459697	0.495	NM_001098616 NM_015449 NM_138740	C1orf43	chromosome 1 open reading frame 43
chr20_-_47965443	0.488		SPATA2	spermatogenesis associated 2
chr16_+_639278	0.485	NM_145294	WDR90	WD repeat domain 90
chr9_-_13269562	0.485		MPDZ	multiple PDZ domain protein
chr6_+_116939500	0.483	NM_153711	FAM26E	family with sequence similarity 26, member E
chr1_+_152459918	0.481	NM_014847	UBAP2L	ubiquitin associated protein 2-like
chr18_-_53621277	0.480	NM_005603	ATP8B1	ATPase, aminophospholipid transporter, class I, type 8B, member 1
chr1_-_154205675	0.480		ARHGEF2	Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr12_+_79634820	0.478	NM_005593	MYF5	myogenic factor 5
chr2_+_228045053	0.476		AGFG1	ArfGAP with FG repeats 1
chr16_-_27468717	0.476		GTF3C1	general transcription factor IIIC, polypeptide 1, alpha 220kDa
chrX_-_34585287	0.475	NM_031442	TMEM47	transmembrane protein 47
chr3_-_36961539	0.474	NM_014831	TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1
chr12_-_57600336	0.473	NM_153377	LRIG3	leucine-rich repeats and immunoglobulin-like domains 3
chr11_+_120399966	0.472	NM_001130047 NM_152715	TBCEL	tubulin folding cofactor E-like
chr19_-_42098758	0.467	NM_001171979	ZNF829	zinc finger protein 829
chr8_-_13416554	0.467	NM_024767 NM_182643	DLC1	deleted in liver cancer 1
chr14_+_23653819	0.466	NM_025230	DCAF11	DDB1 and CUL4 associated factor 11
chr11_+_101290930	0.466	NM_020802	KIAA1377	KIAA1377
chr22_+_34107051	0.465	NM_002133	HMOX1	heme oxygenase (decycling) 1
chr20_+_43952997	0.465	NM_000308 NM_001127695 NM_001167594	CTSA	cathepsin A
chr9_+_119506274	0.458	NM_138554	TLR4	toll-like receptor 4
chr1_-_152459506	0.458		C1orf43	chromosome 1 open reading frame 43
chr1_-_68470585	0.450	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chr8_-_82186832	0.446	NM_018440	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1
chr4_+_108965167	0.445	NM_001136258	SGMS2	sphingomyelin synthase 2
chr6_+_148705421	0.444	NM_015278	SASH1	SAM and SH3 domain containing 1
chrX_-_106846684	0.442		TSC22D3	TSC22 domain family, member 3
chr7_+_28415495	0.440		LOC401317	hypothetical LOC401317
chr6_-_109810396	0.436	NM_001142401 NM_001142402 NM_001142403 NM_001142404 NM_006016	CD164	CD164 molecule, sialomucin
chr20_-_47965474	0.435	NM_006038	SPATA2	spermatogenesis associated 2
chr2_+_42249896	0.433	NM_001145076 NM_019063	EML4	echinoderm microtubule associated protein like 4
chr14_-_23653965	0.432		NRL	neural retina leucine zipper
chr5_+_80292213	0.432		RASGRF2	Ras protein-specific guanine nucleotide-releasing factor 2
chr18_+_7557313	0.431	NM_001105244 NM_002845	PTPRM	protein tyrosine phosphatase, receptor type, M
chr6_+_127629677	0.426	NM_030963	RNF146	ring finger protein 146
chr12_-_57600564	0.424		LRIG3	leucine-rich repeats and immunoglobulin-like domains 3
chr14_+_23654161	0.423		DCAF11	DDB1 and CUL4 associated factor 11
chr12_-_79855580	0.422		LIN7A	lin-7 homolog A (C. elegans)
chr2_-_227372574	0.422		IRS1	insulin receptor substrate 1
chr4_-_23500706	0.422	NM_013261	PPARGC1A	peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr11_-_8695974	0.420		ST5	suppression of tumorigenicity 5
chr9_-_98421894	0.419	NM_003671 NM_033331	CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr5_-_121440704	0.418	NM_001178102	LOX	lysyl oxidase
chr1_-_59020875	0.416		JUN	jun proto-oncogene
chr16_-_65742323	0.415	NM_033309	B3GNT9	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chr10_-_3817205	0.414		KLF6	Kruppel-like factor 6
chr13_+_47776026	0.413		RB1	retinoblastoma 1
chrX_-_102205736	0.413		BEX1	brain expressed, X-linked 1
chr22_+_36928972	0.412	NM_001161573	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr5_+_15553768	0.411		FBXL7	F-box and leucine-rich repeat protein 7
chr17_+_77529070	0.411		ASPSCR1	alveolar soft part sarcoma chromosome region, candidate 1
chr4_-_77354011	0.410	NM_005506	SCARB2	scavenger receptor class B, member 2
chr8_+_103889733	0.410		FLJ45248	FLJ45248 protein
chr12_-_90096275	0.407	NM_133504 NM_133505 NM_133506 NM_133507	DCN	decorin
chr2_+_238200922	0.404	NM_001137550	LRRFIP1	leucine rich repeat (in FLII) interacting protein 1
chr1_-_20685314	0.401	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr16_+_87765661	0.397	NM_004933	CDH15	cadherin 15, type 1, M-cadherin (myotubule)
chr15_-_71712711	0.395	NM_001161363 NM_001161364 NM_012428 NM_017455	NPTN	neuroplastin
chr2_-_160362914	0.395		CD302	CD302 molecule
chr12_+_50731457	0.394	NM_002135 NM_173157	NR4A1	nuclear receptor subfamily 4, group A, member 1
chr10_-_93382837	0.393	NM_005398	PPP1R3C	protein phosphatase 1, regulatory (inhibitor) subunit 3C
chr6_+_87921980	0.392	NM_015021	ZNF292	zinc finger protein 292
chr9_+_77695334	0.391	NM_001190482 NM_006200	PCSK5	proprotein convertase subtilisin/kexin type 5
chr7_-_81910740	0.390		CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr20_-_49818268	0.389		ATP9A	ATPase, class II, type 9A
chr2_+_173000590	0.380		ITGA6	integrin, alpha 6
chr11_+_43658718	0.380	NM_016142	HSD17B12	hydroxysteroid (17-beta) dehydrogenase 12
chr19_-_61680510	0.375	NM_022103	ZNF667	zinc finger protein 667
chr1_+_181258952	0.374	NM_002293	LAMC1	laminin, gamma 1 (formerly LAMB2)
chr17_-_75385371	0.373	NM_020649	CBX8	chromobox homolog 8
chrX_+_102518064	0.371		NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr1_+_152644471	0.370		IL6R	interleukin 6 receptor
chr3_+_44878380	0.369	NM_144638	TMEM42	transmembrane protein 42
chr9_+_119506428	0.369		TLR4	toll-like receptor 4
chrX_-_102205752	0.369	NM_018476	BEX1	brain expressed, X-linked 1
chr9_-_89779413	0.366	NM_001039803 NM_001170639 NM_001170640 NM_012119 NM_178432	CDK20	cyclin-dependent kinase 20
chr4_-_77353713	0.366		SCARB2	scavenger receptor class B, member 2
chr4_+_77446906	0.365		STBD1	starch binding domain 1
chr13_+_112999462	0.365	NM_005561	LAMP1	lysosomal-associated membrane protein 1
chr11_-_8849485	0.364		ST5	suppression of tumorigenicity 5
chr2_+_173000552	0.362	NM_000210 NM_001079818	ITGA6	integrin, alpha 6
chr1_-_112083387	0.362	NM_019099	C1orf183	chromosome 1 open reading frame 183
chr17_+_7416780	0.361	NM_001416	EIF4A1	eukaryotic translation initiation factor 4A1
chrX_+_149282097	0.361	NM_001177465	MAMLD1	mastermind-like domain containing 1
chr9_+_102380156	0.360	NM_001018116	MURC	muscle-related coiled-coil protein
chr8_+_67787206	0.359		SGK3	serum/glucocorticoid regulated kinase family, member 3
chr7_+_27102508	0.356
chr5_-_159730196	0.356	NM_031908	C1QTNF2	C1q and tumor necrosis factor related protein 2
chr4_-_111763655	0.354	NM_000325	PITX2	paired-like homeodomain 2
chr19_+_16296632	0.353	NM_016270	KLF2	Kruppel-like factor 2 (lung)
chr14_+_23654307	0.353	NM_181357	DCAF11	DDB1 and CUL4 associated factor 11
chr4_-_156517394	0.352		MAP9	microtubule-associated protein 9
chr11_-_8788765	0.352	NM_213618	ST5	suppression of tumorigenicity 5
chr4_-_77353778	0.352		SCARB2	scavenger receptor class B, member 2
chr6_+_123152044	0.352		SMPDL3A	sphingomyelin phosphodiesterase, acid-like 3A
chr7_-_81910956	0.351	NM_000722	CACNA2D1	calcium channel, voltage-dependent, alpha 2/delta subunit 1
chrX_+_99785818	0.350	NM_014467	SRPX2	sushi-repeat containing protein, X-linked 2
chr11_+_110916629	0.350		LAYN	layilin
chr12_+_63958949	0.349	NM_001193461	MSRB3	methionine sulfoxide reductase B3
chr10_-_3817418	0.348	NM_001160124 NM_001160125 NM_001300	KLF6	Kruppel-like factor 6
chr16_+_27468942	0.348	NM_015202	KIAA0556	KIAA0556
chr11_+_69165065	0.347		CCND1	cyclin D1
chr5_+_122452739	0.345	NM_001136239	PRDM6	PR domain containing 6
chr7_+_27102197	0.345
chr10_+_11100111	0.344		CELF2	CUGBP, Elav-like family member 2
chr9_-_90983501	0.343	NM_016848	SHC3	SHC (Src homology 2 domain containing) transforming protein 3
chr12_+_63958689	0.343	NM_001031679 NM_001193460 NM_198080	MSRB3	methionine sulfoxide reductase B3
chr10_+_53744043	0.342	NM_012242	DKK1	dickkopf homolog 1 (Xenopus laevis)
chr8_+_11599119	0.341	NM_002052	GATA4	GATA binding protein 4
chr4_-_156517423	0.340		MAP9	microtubule-associated protein 9
chr2_-_20115269	0.339	NM_014713	LAPTM4A	lysosomal protein transmembrane 4 alpha
chr19_-_18912112	0.339	NM_001145722 NM_001145721	HOMER3	homer homolog 3 (Drosophila)
chr6_-_84994032	0.338	NM_014895	KIAA1009	KIAA1009
chr1_-_233879617	0.338	NM_001098722	GNG4	guanine nucleotide binding protein (G protein), gamma 4
chr4_-_77353760	0.337		SCARB2	scavenger receptor class B, member 2
chr2_-_64734544	0.337	NM_014755	SERTAD2	SERTA domain containing 2
chr20_-_6051860	0.336		FERMT1	fermitin family member 1
chr10_-_62373828	0.334	NM_014836	RHOBTB1	Rho-related BTB domain containing 1
chrX_-_106846924	0.334	NM_004089	TSC22D3	TSC22 domain family, member 3
chr5_+_148766632	0.334		LOC728264	hypothetical LOC728264
chr11_+_69165119	0.333		CCND1	cyclin D1
chr2_+_85683473	0.333		USP39	ubiquitin specific peptidase 39
chr10_-_105427898	0.332		SH3PXD2A	SH3 and PX domains 2A
chr16_-_10581944	0.331	NM_001424	EMP2	epithelial membrane protein 2
chr2_-_196744546	0.330	NM_004226	STK17B	serine/threonine kinase 17b
chr1_+_152644292	0.330	NM_000565 NM_181359	IL6R	interleukin 6 receptor
chr3_+_11153778	0.329	NM_001098213	HRH1	histamine receptor H1
chr2_-_85683268	0.329	NM_001031738	TMEM150A	transmembrane protein 150A
chr9_-_126309510	0.329	NM_004959	NR5A1	nuclear receptor subfamily 5, group A, member 1
chr22_+_34025872	0.327		TOM1	target of myb1 (chicken)
chr17_+_30594192	0.326	NM_144975	SLFN5	schlafen family member 5
chr1_-_37792414	0.325	NM_024700	SNIP1	Smad nuclear interacting protein 1

Gene overrepresentation in process category:

enrichment	p-value	GO term	description
1.37	3.92e-04	GO:0033036	macromolecule localization
1.44	6.58e-03	GO:0046907	intracellular transport
1.23	1.31e-02	GO:0048522	positive regulation of cellular process
1.20	4.13e-02	GO:0048518	positive regulation of biological process
1.33	4.65e-02	GO:0051649	establishment of localization in cell

Gene overrepresentation in compartment category:

enrichment	p-value	GO term	description
1.08	3.42e-06	GO:0005622	intracellular
1.08	6.66e-06	GO:0044424	intracellular part
1.09	5.55e-03	GO:0005737	cytoplasm
1.07	1.40e-02	GO:0043229	intracellular organelle
1.07	1.49e-02	GO:0043226	organelle
1.11	4.81e-02	GO:0005634	nucleus

Gene overrepresentation in function category:

enrichment	p-value	GO term	description
1.14	3.24e-07	GO:0005515	protein binding
2.68	1.38e-02	GO:0003707	steroid hormone receptor activity
1.06	1.95e-02	GO:0005488	binding
2.54	3.69e-02	GO:0004879	ligand-dependent nuclear receptor activity