Motif ID: NR3C1.p2

Z-value: 0.741


Transcription factors associated with NR3C1.p2:

Gene SymbolEntrez IDGene Name
NR3C1 2908 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NR3C1chr5_-_142763481-0.457.8e-02Click!


Activity profile for motif NR3C1.p2.

activity profile for motif NR3C1.p2


Sorted Z-values histogram for motif NR3C1.p2

Sorted Z-values for motif NR3C1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR3C1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_92670764 1.167 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr2_-_233586145 1.036 NGEF
neuronal guanine nucleotide exchange factor
chr17_+_42641712 1.017 NM_002476
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr6_+_36752244 0.986 NM_078467
CDKN1A
cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr2_-_233586164 0.949 NM_019850
NGEF
neuronal guanine nucleotide exchange factor
chr6_+_64289585 0.900 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr10_-_92671005 0.882 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr17_+_42641426 0.793 NM_001002841
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr6_-_48186868 0.771 C6orf138
chromosome 6 open reading frame 138
chr22_-_37480898 0.683 SUN2
Sad1 and UNC84 domain containing 2
chr5_+_140690387 0.628 NM_018912
NM_031993
PCDHGA1

protocadherin gamma subfamily A, 1

chr3_+_173043832 0.611 NM_001164436
TMEM212
transmembrane protein 212
chr5_+_149867866 0.561 NM_001543
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr7_+_94377145 0.537 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory (inhibitor) subunit 9A


chr10_+_70517823 0.520 NM_002727
SRGN
serglycin
chr14_-_23686269 0.516 PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr15_-_43280664 0.494 NM_138356
SHF
Src homology 2 domain containing F
chr19_+_15644885 0.493 NM_023944
CYP4F12
cytochrome P450, family 4, subfamily F, polypeptide 12
chr16_+_70654625 0.493 NM_020995
HPR
haptoglobin-related protein
chr13_+_75092570 0.492 NM_005358
LMO7
LIM domain 7
chr16_-_66075216 0.480 NM_001138
AGRP
agouti related protein homolog (mouse)
chr9_-_70780574 0.453


chr6_-_6265874 0.445 F13A1
coagulation factor XIII, A1 polypeptide
chr14_+_99309688 0.436 EML1
echinoderm microtubule associated protein like 1
chr4_-_139382672 0.430 NM_014331
SLC7A11
solute carrier family 7, (cationic amino acid transporter, y+ system) member 11
chr5_-_42847716 0.430 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr20_-_10360569 0.428 NM_018848
MKKS
McKusick-Kaufman syndrome
chr16_+_8722068 0.424 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr13_+_112825113 0.419 NM_000504
F10
coagulation factor X
chr14_+_23686547 0.415 RNF31
ring finger protein 31
chr11_-_8695974 0.414 ST5
suppression of tumorigenicity 5
chr17_+_35078032 0.403 NM_002686
PNMT
phenylethanolamine N-methyltransferase
chr14_+_34831294 0.382 NM_002791
PSMA6
proteasome (prosome, macropain) subunit, alpha type, 6
chr14_-_35859545 0.370 NM_001144891
NM_016586
MBIP

MAP3K12 binding inhibitory protein 1

chr20_+_29598848 0.368 HM13
histocompatibility (minor) 13
chr2_+_143603368 0.363 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr19_-_47724365 0.360 NM_001024912
NM_001184813
NM_001184815
NM_001184816
NM_001712
CEACAM1




carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)




chr12_-_9804682 0.359 NM_001781
CD69
CD69 molecule
chr18_-_53438854 0.357


chr5_-_16791346 0.355 MYO10
myosin X
chr1_-_94359266 0.355 NM_000350
ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
chr19_-_15869870 0.353 NM_001082
CYP4F2
cytochrome P450, family 4, subfamily F, polypeptide 2
chr14_+_23686498 0.349 NM_017999
RNF31
ring finger protein 31
chr6_-_6265896 0.342 NM_000129
F13A1
coagulation factor XIII, A1 polypeptide
chr1_-_177106702 0.336 NM_004673
ANGPTL1
angiopoietin-like 1
chr16_-_67943157 0.325 NM_144676
TMED6
transmembrane emp24 protein transport domain containing 6
chr20_+_55569542 0.323 NM_002591
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr10_+_24795465 0.322 KIAA1217
KIAA1217
chr10_+_24795446 0.321 KIAA1217
KIAA1217
chr4_+_74496660 0.317 ALB
albumin
chr2_+_43919606 0.311 NM_022437
ABCG8
ATP-binding cassette, sub-family G (WHITE), member 8
chr11_+_73036241 0.306 NM_001130034
NM_001130035
PLEKHB1

pleckstrin homology domain containing, family B (evectins) member 1

chr3_+_152970904 0.300 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr12_+_49605010 0.299 METTL7A
methyltransferase like 7A
chr2_+_37282516 0.293 LOC100505876
hypothetical LOC100505876
chr2_-_56266408 0.287 LOC100129434
hypothetical LOC100129434
chr11_-_118693021 0.280 NM_006500
MCAM
melanoma cell adhesion molecule
chr4_-_159312973 0.278 FAM198B
family with sequence similarity 198, member B
chr20_+_61838389 0.274 NM_017806
LIME1
Lck interacting transmembrane adaptor 1
chr12_+_49604782 0.272 NM_014033
METTL7A
methyltransferase like 7A
chr22_+_21042091 0.268 IGLV1-44
IGL@
immunoglobulin lambda variable 1-44
immunoglobulin lambda locus
chr17_-_36418869 0.267 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr4_-_155731288 0.264 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr16_-_70591377 0.263 NM_181536
PKD1L3
polycystic kidney disease 1-like 3
chr12_-_49708279 0.262 NM_001174125
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr1_-_205161821 0.259 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr12_+_56114724 0.258 NM_005538
INHBC
inhibin, beta C
chr1_-_158759606 0.255 NM_001184714
NM_001184715
NM_001184716
NM_052931
SLAMF6



SLAM family member 6



chr4_-_95482994 0.254 NM_014485
HPGDS
hematopoietic prostaglandin D synthase
chrX_+_46825179 0.254 RGN
regucalcin (senescence marker protein-30)
chrX_+_153423652 0.253 NM_001099856
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr14_-_64416307 0.246 SPTB
spectrin, beta, erythrocytic
chr21_+_45396903 0.242 ADARB1
adenosine deaminase, RNA-specific, B1
chr22_-_35835548 0.241 TMPRSS6
transmembrane protease, serine 6
chr22_+_21053972 0.241


chr21_+_37713076 0.233 NM_130436
DYRK1A
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
chr1_+_172060440 0.230 DARS2
aspartyl-tRNA synthetase 2, mitochondrial
chr5_+_133870175 0.228


chr2_-_238164042 0.228 RAB17
RAB17, member RAS oncogene family
chr17_+_75366524 0.228 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr17_-_23928048 0.218 NM_005165
ALDOC
aldolase C, fructose-bisphosphate
chr6_-_31756119 0.214 NM_025262
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr1_-_159546348 0.212 NM_000530
MPZ
myelin protein zero
chr17_+_7900926 0.212


chr10_-_73953699 0.211 NM_001195519
CBARA1
calcium binding atopy-related autoantigen 1
chr12_+_79625538 0.210 NM_002469
MYF6
myogenic factor 6 (herculin)
chr10_+_685887 0.209 C10orf108
chromosome 10 open reading frame 108
chr17_-_23928041 0.209 ALDOC
aldolase C, fructose-bisphosphate
chr10_-_76538859 0.209 NM_001007271
NM_001007272
NM_001007273
DUSP13


dual specificity phosphatase 13


chr17_-_53849929 0.208 NM_017763
RNF43
ring finger protein 43
chr12_+_68028397 0.207 NM_000239
LYZ
lysozyme
chr8_-_13018123 0.205 NM_001164271
DLC1
deleted in liver cancer 1
chr12_-_51585004 0.203 NM_002273
KRT8
keratin 8
chrX_+_65300803 0.201 NM_001130860
NM_014799
HEPH

hephaestin

chr8_-_101384633 0.201 NM_015435
RNF19A
ring finger protein 19A
chr10_+_91142301 0.201 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr11_+_55362802 0.198 NM_001005496
OR5D16
olfactory receptor, family 5, subfamily D, member 16
chr19_-_5821546 0.196 NM_002034
FUT5
fucosyltransferase 5 (alpha (1,3) fucosyltransferase)
chr5_-_149649380 0.196 CAMK2A
calcium/calmodulin-dependent protein kinase II alpha
chr11_+_19328846 0.192 NM_001111018
NAV2
neuron navigator 2
chr22_+_33792125 0.190 NM_001008494
ISX
intestine-specific homeobox
chr3_-_52712639 0.190 NM_152932
GLT8D1
glycosyltransferase 8 domain containing 1
chr1_+_67404756 0.189 NM_144701
IL23R
interleukin 23 receptor
chr17_-_23927973 0.189 ALDOC
aldolase C, fructose-bisphosphate
chr20_+_61838479 0.188 LIME1
Lck interacting transmembrane adaptor 1
chr5_+_143171918 0.186 NM_021182
HMHB1
histocompatibility (minor) HB-1
chr7_-_97339616 0.184 ASNS
asparagine synthetase (glutamine-hydrolyzing)
chr22_-_40666168 0.184 NM_001110215
CENPM
centromere protein M
chr16_+_30293598 0.183 NM_013292
MYLPF
myosin light chain, phosphorylatable, fast skeletal muscle
chr1_+_111544469 0.183


chr1_-_54256390 0.183 NM_001010978
LDLRAD1
low density lipoprotein receptor class A domain containing 1
chr8_-_29176490 0.182 NM_015254
KIF13B
kinesin family member 13B
chr17_-_10265991 0.181 NM_002472
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr14_-_34252695 0.180 NM_021914
CFL2
cofilin 2 (muscle)
chr1_-_181889070 0.180 NM_203454
APOBEC4
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr15_-_72288362 0.180 NM_001142617
NM_001142619
NM_001142620
STRA6


stimulated by retinoic acid gene 6 homolog (mouse)


chr19_-_2233174 0.179 NM_198532
C19orf35
chromosome 19 open reading frame 35
chr1_-_219977424 0.178 NM_144728
DUSP10
dual specificity phosphatase 10
chr8_+_1940282 0.176 KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr10_+_70517863 0.173 SRGN
serglycin
chr22_+_39404940 0.173 NM_005297
MCHR1
melanin-concentrating hormone receptor 1
chr12_+_6925997 0.173 NM_080548
PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr1_+_111571803 0.173 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr20_+_42463350 0.171 HNF4A
hepatocyte nuclear factor 4, alpha
chr9_-_124370576 0.171 NM_001004454
OR1L8
olfactory receptor, family 1, subfamily L, member 8
chr5_-_78318112 0.169 NM_000046
ARSB
arylsulfatase B
chr6_-_154873480 0.168 CNKSR3
CNKSR family member 3
chr7_+_128795280 0.167 AHCYL2
adenosylhomocysteinase-like 2
chr17_-_34014390 0.166 SRCIN1
SRC kinase signaling inhibitor 1
chr17_-_59363352 0.165 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr20_-_20641122 0.165 NM_020343
RALGAPA2
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr7_-_112545840 0.162 LOC401397
hypothetical LOC401397
chr1_-_184684478 0.162 NM_022576
PDC
phosducin
chr7_-_112545847 0.161 LOC401397
hypothetical LOC401397
chr20_-_45418818 0.161 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr7_-_122126422 0.161 NM_139175
RNF133
ring finger protein 133
chr1_-_111544603 0.161


chr4_+_35962038 0.159 NM_001170700
DTHD1
death domain containing 1
chr1_+_12325632 0.158 VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr4_+_74498042 0.156 ALB
albumin
chr3_+_99733432 0.156 NM_005290
GPR15
G protein-coupled receptor 15
chr6_-_127705244 0.155 NM_001139510
ECHDC1
enoyl CoA hydratase domain containing 1
chr12_+_68028407 0.155 LYZ
lysozyme
chr1_+_144124547 0.154 NM_145277
NM_202004
NM_213652
NM_213653
HFE2



hemochromatosis type 2 (juvenile)



chr2_-_75650355 0.153 NM_032181
FAM176A
family with sequence similarity 176, member A
chrX_+_65299157 0.153 NM_138737
HEPH
hephaestin
chr6_-_41823056 0.150 NM_001166424
NM_002630
PGC

progastricsin (pepsinogen C)

chr7_-_143587653 0.150 NM_001005328
OR2A7
OR2A4
olfactory receptor, family 2, subfamily A, member 7
olfactory receptor, family 2, subfamily A, member 4
chr12_-_16649211 0.149 LMO3
LIM domain only 3 (rhombotin-like 2)
chr17_-_53849888 0.148 RNF43
ring finger protein 43
chr11_+_66927976 0.148 NM_198517
TBC1D10C
TBC1 domain family, member 10C
chr2_-_43919392 0.148 NM_022436
ABCG5
ATP-binding cassette, sub-family G (WHITE), member 5
chr10_+_5478521 0.147 NM_005863
NET1
neuroepithelial cell transforming 1
chr8_-_62764839 0.146 NM_001164750
NM_001164751
NM_001164752
NM_001164753
NM_020164
NM_032467
NM_032468
ASPH






aspartate beta-hydroxylase






chr12_-_69837831 0.146 TSPAN8
tetraspanin 8
chr20_-_18425811 0.144 NM_006606
RBBP9
retinoblastoma binding protein 9
chrX_-_48212683 0.140 SLC38A5
solute carrier family 38, member 5
chr6_+_158653679 0.137 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr8_-_31010772 0.134 NM_001015508
PURG
purine-rich element binding protein G
chr14_-_22825072 0.134 HOMEZ
homeobox and leucine zipper encoding
chr1_-_199657468 0.133 NM_003281
TNNI1
troponin I type 1 (skeletal, slow)
chr11_-_117589283 0.129 NM_153206
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr2_-_215998181 0.129 FN1
fibronectin 1
chr1_-_111544784 0.129 NM_024901
DENND2D
DENN/MADD domain containing 2D
chr16_+_20682812 0.129 NM_005622
NM_202000
ACSM3

acyl-CoA synthetase medium-chain family member 3

chr4_+_114190233 0.129 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr10_-_69125932 0.128 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr1_-_26266571 0.127 NM_032588
TRIM63
tripartite motif containing 63
chr6_-_89984214 0.127 NM_002042
GABRR1
gamma-aminobutyric acid (GABA) receptor, rho 1
chr12_+_6926014 0.126 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chrX_+_100764757 0.126 NM_016607
NM_177947
ARMCX3

armadillo repeat containing, X-linked 3

chr1_+_156490550 0.124 NM_001763
CD1A
CD1a molecule
chr1_-_60164912 0.124 NM_000775
CYP2J2
cytochrome P450, family 2, subfamily J, polypeptide 2
chr6_-_154873396 0.123 NM_173515
CNKSR3
CNKSR family member 3
chr3_+_52254782 0.123 PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr11_-_47467094 0.122 NM_001025596
NM_001172640
CELF1

CUGBP, Elav-like family member 1

chr6_-_130224108 0.121 NM_001010876
C6orf191
chromosome 6 open reading frame 191
chr6_+_28237529 0.119 NM_001145129
ZNF389
zinc finger protein 389
chr4_+_74497998 0.118 ALB
albumin
chr20_+_42463387 0.118 HNF4A
hepatocyte nuclear factor 4, alpha
chr6_+_26264531 0.117 HIST1H1E
histone cluster 1, H1e
chr19_-_62680703 0.117 NM_001024596
NM_001144068
ZNF772

zinc finger protein 772

chr13_+_45174446 0.116 NM_152719
SPERT
spermatid associated
chr5_+_171553780 0.115 NM_001171183
EFCAB9
EF-hand calcium binding domain 9
chr9_+_130723507 0.115 PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr4_+_2783743 0.115 NM_001145855
SH3BP2
SH3-domain binding protein 2
chr2_+_230900121 0.114 NM_138402
SP140L
SP140 nuclear body protein-like
chr7_-_86812629 0.114 TP53TG1
TP53 target 1 (non-protein coding)
chr14_+_20226762 0.113 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr10_+_114144512 0.113 ACSL5
acyl-CoA synthetase long-chain family member 5
chr17_-_71352182 0.112 NM_199242
UNC13D
unc-13 homolog D (C. elegans)
chrX_+_128741578 0.112 SASH3
SAM and SH3 domain containing 3
chr17_-_40843530 0.112 ARHGAP27
Rho GTPase activating protein 27
chr12_-_69838045 0.111 NM_004616
TSPAN8
tetraspanin 8
chr1_-_54861656 0.110 NM_176782
FAM151A
family with sequence similarity 151, member A
chr6_+_150731720 0.110 NM_001164694
NM_001164695
NM_203395
IYD


iodotyrosine deiodinase


chr18_-_46600295 0.110 NM_001127175
NM_001127176
NM_031939
MRO


maestro


chr13_+_97403929 0.109 NM_002271
IPO5
importin 5
chr1_-_240228987 0.108 NM_001004343
MAP1LC3C
microtubule-associated protein 1 light chain 3 gamma
chr19_+_40511909 0.106 NM_001185099
NM_001185100
NM_001185101
NM_001771
CD22



CD22 molecule




Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.