Motif ID: SPZ1.p2

Z-value: 1.047


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
SPZ1 84654 spermatogenic leucine zipper 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPZ1chr5_+_79651545-0.485.7e-02Click!


Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_29819647 1.318 NM_181718
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr4_-_22126437 1.206 NM_145290
GPR125
G protein-coupled receptor 125
chr2_-_220144254 1.151 OBSL1
obscurin-like 1
chr4_+_184257337 1.140 NM_024949
WWC2
WW and C2 domain containing 2
chrX_+_105856531 1.097 NM_194463
RNF128
ring finger protein 128
chr6_-_116488458 1.070 NM_002031
FRK
fyn-related kinase
chr17_+_72795567 1.030 NM_001113492
SEPT9
septin 9
chrX_-_128485121 1.029 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr1_-_20684858 0.963 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr16_-_66535457 0.934 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr7_+_94374862 0.926 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr20_-_22513050 0.905 NM_021784
FOXA2
forkhead box A2
chr7_+_45894480 0.874 NM_000596
IGFBP1
insulin-like growth factor binding protein 1
chr3_-_187025438 0.853 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr2_+_54536780 0.836 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr18_-_26935883 0.835 NM_004949
NM_024422
DSC2

desmocollin 2

chr10_+_123862430 0.808 TACC2
transforming, acidic coiled-coil containing protein 2
chr12_+_64504835 0.784 HMGA2
high mobility group AT-hook 2
chr3_-_187025501 0.780 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr6_-_128883125 0.773 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr14_-_22516271 0.771 NM_198086
JUB
jub, ajuba homolog (Xenopus laevis)
chr9_-_106730157 0.740 ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr4_-_187884721 0.705


chr20_-_42457717 0.696


chr1_-_159459999 0.692 NM_001643
APOA2
apolipoprotein A-II
chr9_+_115957537 0.688 COL27A1
collagen, type XXVII, alpha 1
chr1_-_150070849 0.677 NM_005060
RORC
RAR-related orphan receptor C
chr20_-_30535045 0.670 C20orf112
chromosome 20 open reading frame 112
chrX_-_132947290 0.648 NM_001164617
NM_001164618
NM_001164619
NM_004484
GPC3



glypican 3



chrX_-_132947141 0.647 GPC3
glypican 3
chr11_-_70641267 0.636 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr2_+_171280944 0.633 SP5
Sp5 transcription factor
chr11_-_2116775 0.625 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr16_-_66535923 0.623 SLC12A4
solute carrier family 12 (potassium/chloride transporters), member 4
chr6_-_47385205 0.615 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr16_+_29373365 0.612 NM_001014999
NM_001015000
NM_024044
NM_178044
SLX1A-SULT1A3
SLX1A

SLX1B

SLX1A-SULT1A3 read-through transcript
SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae)

SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)

chr17_-_36469869 0.606 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr12_-_52980914 0.598 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chrX_-_128485062 0.592 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr12_-_47468985 0.583 NM_020983
ADCY6
adenylate cyclase 6
chr6_-_138231006 0.581


chr16_-_49742008 0.575 NM_001127892
SALL1
sal-like 1 (Drosophila)
chr3_-_24511180 0.571 NM_001128176
NM_000461
NM_001128177
THRB


thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)


chr19_+_40223249 0.569 NM_002151
NM_182983
HPN

hepsin

chr1_+_199130571 0.566 NM_001142569
C1orf106
chromosome 1 open reading frame 106
chr20_-_17610704 0.558 RRBP1
ribosome binding protein 1 homolog 180kDa (dog)
chr3_+_125786195 0.554 NM_007064
KALRN
kalirin, RhoGEF kinase
chr7_-_103417198 0.550 NM_005045
NM_173054
RELN

reelin

chr20_-_22512893 0.543 FOXA2
forkhead box A2
chr2_+_119905812 0.540 NM_183240
TMEM37
transmembrane protein 37
chr12_+_106236281 0.539 NM_001018072
BTBD11
BTB (POZ) domain containing 11
chr16_-_51138306 0.532 NM_001080430
TOX3
TOX high mobility group box family member 3
chr14_-_24588916 0.525 NM_014178
STXBP6
syntaxin binding protein 6 (amisyn)
chr6_+_132170888 0.523 ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr6_-_47385313 0.520 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr3_-_24511456 0.518 THRB
thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian)
chr14_+_23937766 0.515 NM_025081
NYNRIN
NYN domain and retroviral integrase containing
chr13_-_33148899 0.509 STARD13
StAR-related lipid transfer (START) domain containing 13
chr17_-_77824849 0.507 NM_001893
NM_139062
CSNK1D

casein kinase 1, delta

chr10_-_105411339 0.505 SH3PXD2A
SH3 and PX domains 2A
chr9_+_115958051 0.497 NM_032888
COL27A1
collagen, type XXVII, alpha 1
chr6_+_32090516 0.495 NM_007293
NM_001002029
C4A
C4B
complement component 4A (Rodgers blood group)
complement component 4B (Chido blood group)
chr18_-_50777634 0.492 NM_025214
CCDC68
coiled-coil domain containing 68
chr2_+_70981223 0.489 NM_012476
VAX2
ventral anterior homeobox 2
chr6_-_138470160 0.488 NM_022121
PERP
PERP, TP53 apoptosis effector
chr13_+_92677012 0.485 NM_005708
GPC6
glypican 6
chr16_+_49139694 0.482 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr2_-_20075889 0.480 MATN3
matrilin 3
chr6_+_43151922 0.479 NM_002821
NM_152880
NM_152881
NM_152882
PTK7



PTK7 protein tyrosine kinase 7



chr11_+_2116486 0.477


chr20_+_3399615 0.477 NM_139321
NM_139322
ATRN

attractin

chr14_-_60260780 0.475 SIX4
SIX homeobox 4
chr2_-_20075929 0.474 NM_002381
MATN3
matrilin 3
chr3_+_112273352 0.461 PVRL3
poliovirus receptor-related 3
chr2_+_70981233 0.457 VAX2
ventral anterior homeobox 2
chr20_-_17610828 0.455 NM_001042576
NM_004587
RRBP1

ribosome binding protein 1 homolog 180kDa (dog)

chr16_+_65701428 0.453


chr20_-_22514092 0.452 NM_153675
FOXA2
forkhead box A2
chr11_-_116168316 0.450 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr2_-_174538197 0.449 SP3
Sp3 transcription factor
chr4_-_158111995 0.446 NM_016205
PDGFC
platelet derived growth factor C
chr9_-_79835970 0.444 NM_002072
GNAQ
guanine nucleotide binding protein (G protein), q polypeptide
chr16_+_65701284 0.442 NM_025187
C16orf70
chromosome 16 open reading frame 70
chr17_+_69939806 0.441 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr11_+_101488380 0.440 NM_001195045
YAP1
Yes-associated protein 1
chr11_-_10272256 0.440 NM_030962
SBF2
SET binding factor 2
chr1_-_151848039 0.439 S100A16
S100 calcium binding protein A16
chr1_-_21868380 0.438 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr4_-_158111504 0.436 PDGFC
platelet derived growth factor C
chr2_+_242400702 0.434 NM_001167599
NM_001167602
NM_080741
NEU4


sialidase 4


chr2_+_46378405 0.430 EPAS1
endothelial PAS domain protein 1
chr14_-_20975241 0.429 NM_020920
CHD8
chromodomain helicase DNA binding protein 8
chr17_+_35147697 0.428 NM_005310
GRB7
growth factor receptor-bound protein 7
chr2_-_42873179 0.425 NM_012205
HAAO
3-hydroxyanthranilate 3,4-dioxygenase
chr6_-_119712596 0.424 NM_005907
MAN1A1
mannosidase, alpha, class 1A, member 1
chr2_-_161058120 0.421 RBMS1
RNA binding motif, single stranded interacting protein 1
chr6_+_37245860 0.420 NM_002648
PIM1
pim-1 oncogene
chr9_-_106730256 0.420 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr20_+_35240844 0.418 NM_001135771
NM_002951
RPN2

ribophorin II

chr8_+_76482661 0.417 HNF4G
hepatocyte nuclear factor 4, gamma
chr6_-_47385470 0.416 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr22_-_19122047 0.415 SCARF2
scavenger receptor class F, member 2
chr15_-_72804763 0.413 NM_000499
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr3_+_37878647 0.413 NM_001008392
NM_005808
CTDSPL

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like

chr17_-_33178987 0.413 HNF1B
HNF1 homeobox B
chr3_-_48445719 0.412 NM_002673
PLXNB1
plexin B1
chr1_-_24307514 0.411 MYOM3
myomesin family, member 3
chr10_-_101680645 0.411 DNMBP
dynamin binding protein
chr19_-_6671585 0.410 NM_000064
C3
complement component 3
chr13_-_74953873 0.408 NM_014832
TBC1D4
TBC1 domain family, member 4
chr7_+_29200850 0.408 CHN2
chimerin (chimaerin) 2
chr2_-_101134146 0.407 NM_001102426
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr12_+_55808696 0.407 LRP1
low density lipoprotein receptor-related protein 1
chr1_-_11909042 0.406 NM_138346
KIAA2013
KIAA2013
chr20_+_35241109 0.404 RPN2
ribophorin II
chr9_-_85342868 0.401 NM_174938
FRMD3
FERM domain containing 3
chr18_+_30812205 0.398 NM_001143827
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr9_+_70926009 0.398 NM_001170414
TJP2
tight junction protein 2 (zona occludens 2)
chr12_+_6290359 0.397 NM_001144856
PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr20_+_35241161 0.397 RPN2
ribophorin II
chr6_-_24466258 0.395 NM_016356
DCDC2
doublecortin domain containing 2
chr17_+_33761234 0.394 NM_014598
SOCS7
suppressor of cytokine signaling 7
chr16_+_66438348 0.391 NUTF2
nuclear transport factor 2
chr3_+_30622905 0.388 NM_001024847
NM_003242
TGFBR2

transforming growth factor, beta receptor II (70/80kDa)

chr10_-_105604942 0.388 NM_014631
SH3PXD2A
SH3 and PX domains 2A
chr3_-_189354510 0.387 LOC339929
hypothetical LOC339929
chr17_-_33179118 0.387 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr16_-_49742651 0.386 NM_002968
SALL1
sal-like 1 (Drosophila)
chr11_-_2116501 0.384 IGF2
insulin-like growth factor 2 (somatomedin A)
chr17_+_14145051 0.383 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr7_+_29200636 0.382 NM_004067
CHN2
chimerin (chimaerin) 2
chr16_+_28741861 0.380 ATXN2L
ataxin 2-like
chr14_-_22974707 0.378 NM_000257
MYH7
myosin, heavy chain 7, cardiac muscle, beta
chr20_+_35240936 0.377 RPN2
ribophorin II
chr14_-_23686269 0.377 PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr11_-_2116360 0.375 IGF2
insulin-like growth factor 2 (somatomedin A)
chr17_-_40858775 0.374 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr5_+_80292313 0.372 NM_006909
RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chr12_+_6290127 0.372 PLEKHG6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr7_-_37923040 0.372 NM_003014
SFRP4
secreted frizzled-related protein 4
chr14_-_20636337 0.370 ZNF219
zinc finger protein 219
chr14_-_37133927 0.370 FOXA1
forkhead box A1
chr5_+_80292213 0.370 RASGRF2
Ras protein-specific guanine nucleotide-releasing factor 2
chrX_-_128485134 0.365 NM_003069
NM_139035
SMARCA1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1

chr2_-_73193581 0.365 NM_015470
RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr2_-_161058550 0.362 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr2_-_220144427 0.361 OBSL1
obscurin-like 1
chr10_-_71753684 0.359 LRRC20
leucine rich repeat containing 20
chr16_+_28785087 0.357 SH2B1
SH2B adaptor protein 1
chr16_-_52877868 0.354 NM_024336
IRX3
iroquois homeobox 3
chr12_+_6363482 0.354 NM_002342
LTBR
lymphotoxin beta receptor (TNFR superfamily, member 3)
chr2_-_36384 0.353 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr6_+_108988797 0.351 FOXO3
forkhead box O3
chr10_+_114700775 0.351 TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr14_+_34521945 0.350 SRP54
signal recognition particle 54kDa
chr2_-_220144511 0.349 NM_001173408
NM_001173431
NM_015311
OBSL1


obscurin-like 1


chr14_+_34521854 0.347 NM_001146282
NM_003136
SRP54

signal recognition particle 54kDa

chr16_+_66438285 0.346 NM_005796
NUTF2
nuclear transport factor 2
chr2_+_219780192 0.344 ZFAND2B
zinc finger, AN1-type domain 2B
chr17_-_67628523 0.342 FLJ37644
hypothetical LOC400618
chr10_-_118419459 0.342 NM_144661
C10orf82
chromosome 10 open reading frame 82
chr11_+_45900731 0.341 GYLTL1B
glycosyltransferase-like 1B
chr19_+_6415259 0.341 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr17_-_38978253 0.339 ETV4
ets variant 4
chr4_-_158111916 0.338 PDGFC
platelet derived growth factor C
chr5_+_129268352 0.337 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr3_+_9933763 0.337 NM_032732
NM_153460
NM_153461
IL17RC


interleukin 17 receptor C


chr2_-_73193566 0.333 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr17_-_53387493 0.332 CUEDC1
CUE domain containing 1
chr19_+_50041387 0.331 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr21_-_36774257 0.331 NM_001146079
NM_144492
CLDN14

claudin 14

chr5_-_172689111 0.329 NM_003714
STC2
stanniocalcin 2
chr11_-_47164514 0.328 NM_001184974
NM_016223
PACSIN3

protein kinase C and casein kinase substrate in neurons 3

chr19_+_49972965 0.327 NM_001130852
NM_012116
CBLC

Cas-Br-M (murine) ecotropic retroviral transforming sequence c

chr18_+_3439972 0.324 NM_173209
NM_173208
NM_003244
TGIF1


TGFB-induced factor homeobox 1


chr19_+_50041400 0.324 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr20_-_25514137 0.324 NM_025176
NINL
ninein-like
chr2_-_160972606 0.323 RBMS1
RNA binding motif, single stranded interacting protein 1
chr2_-_11402150 0.323 NM_004850
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr2_+_113119985 0.322 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr22_-_22970850 0.322 NM_001099781
NM_001099782
NM_004121
GGT5


gamma-glutamyltransferase 5


chr15_-_81412354 0.321 NM_004839
NM_199330
NM_199331
NM_199332
HOMER2



homer homolog 2 (Drosophila)



chr1_-_56817802 0.320 PPAP2B
phosphatidic acid phosphatase type 2B
chr12_+_970613 0.320 NM_178039
NM_178040
ERC1

ELKS/RAB6-interacting/CAST family member 1

chr3_-_147361465 0.319 PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
chr20_-_47238082 0.317 STAU1
staufen, RNA binding protein, homolog 1 (Drosophila)
chr11_+_69165159 0.317 CCND1
cyclin D1
chr12_+_51730101 0.317 NM_170754
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr1_-_159459814 0.315 APOA2
apolipoprotein A-II
chr7_+_989321 0.314 NM_017781
CYP2W1
cytochrome P450, family 2, subfamily W, polypeptide 1
chr12_-_52980984 0.312 NM_001136023
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr17_-_53420595 0.312 NM_007146
VEZF1
vascular endothelial zinc finger 1
chr17_+_44429748 0.311 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr20_+_3399727 0.308 ATRN
attractin
chr19_+_50041424 0.306 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr17_-_38978772 0.305 NM_001986
ETV4
ets variant 4
chr17_-_77602493 0.304 RFNG
RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_+_219779737 0.302 NM_138802
ZFAND2B
zinc finger, AN1-type domain 2B
chr4_-_118226119 0.300 NM_152402
TRAM1L1
translocation associated membrane protein 1-like 1
chr12_+_48784057 0.299 NM_005276
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.35 1.94e-07 GO:0007399 nervous system development
1.08 3.41e-07 GO:0009987 cellular process
1.33 1.40e-06 GO:0009653 anatomical structure morphogenesis
1.19 2.70e-06 GO:0032502 developmental process
1.19 7.02e-06 GO:0007275 multicellular organismal development
1.42 8.85e-06 GO:0006351 transcription, DNA-dependent
1.21 9.33e-06 GO:0048731 system development
1.20 2.21e-05 GO:0048856 anatomical structure development
2.01 3.82e-05 GO:0034330 cell junction organization
1.11 2.42e-04 GO:0050794 regulation of cellular process
1.38 2.53e-04 GO:0048699 generation of neurons
1.17 2.61e-04 GO:0080090 regulation of primary metabolic process
1.23 2.97e-04 GO:0030154 cell differentiation
1.43 5.92e-04 GO:0032989 cellular component morphogenesis
1.97 5.96e-04 GO:0034329 cell junction assembly
1.24 6.42e-04 GO:0010467 gene expression
1.22 7.73e-04 GO:0048869 cellular developmental process
1.35 8.10e-04 GO:0022008 neurogenesis
1.16 8.89e-04 GO:0031323 regulation of cellular metabolic process
1.34 9.94e-04 GO:0032774 RNA biosynthetic process
1.09 1.50e-03 GO:0065007 biological regulation
1.47 1.75e-03 GO:0000904 cell morphogenesis involved in differentiation
1.24 2.06e-03 GO:0016070 RNA metabolic process
1.62 2.69e-03 GO:0061061 muscle structure development
1.09 2.87e-03 GO:0050789 regulation of biological process
1.16 4.06e-03 GO:0034641 cellular nitrogen compound metabolic process
1.41 5.35e-03 GO:0000902 cell morphogenesis
1.37 5.39e-03 GO:0030182 neuron differentiation
1.14 5.51e-03 GO:0019222 regulation of metabolic process
1.14 5.71e-03 GO:0023052 signaling
1.25 6.25e-03 GO:0009966 regulation of signal transduction
1.17 6.93e-03 GO:0048518 positive regulation of biological process
1.32 6.98e-03 GO:0048468 cell development
1.10 7.14e-03 GO:0044237 cellular metabolic process
1.37 7.57e-03 GO:0009790 embryo development
1.31 8.03e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.15 8.84e-03 GO:0006807 nitrogen compound metabolic process
2.06 8.97e-03 GO:0045216 cell-cell junction organization
1.27 1.33e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.27 1.52e-02 GO:0031325 positive regulation of cellular metabolic process
1.12 1.55e-02 GO:0044260 cellular macromolecule metabolic process
1.17 1.65e-02 GO:0051171 regulation of nitrogen compound metabolic process
1.15 1.76e-02 GO:0060255 regulation of macromolecule metabolic process
1.79 2.12e-02 GO:0001655 urogenital system development
1.98 2.22e-02 GO:0030278 regulation of ossification
1.17 2.70e-02 GO:0048522 positive regulation of cellular process
1.25 2.90e-02 GO:0009893 positive regulation of metabolic process
1.11 3.34e-02 GO:0043170 macromolecule metabolic process
1.43 4.09e-02 GO:0048812 neuron projection morphogenesis
1.36 4.18e-02 GO:0030030 cell projection organization
1.16 4.79e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32 4.80e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.08 4.90e-02 GO:0008152 metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.58 1.86e-09 GO:0030054 cell junction
2.00 3.86e-07 GO:0070161 anchoring junction
1.99 3.20e-06 GO:0005912 adherens junction
1.06 1.45e-05 GO:0044424 intracellular part
1.06 1.02e-04 GO:0005622 intracellular
2.00 1.74e-04 GO:0044449 contractile fiber part
1.19 9.39e-04 GO:0044459 plasma membrane part
1.91 1.17e-03 GO:0030016 myofibril
1.88 1.28e-03 GO:0043292 contractile fiber
1.68 1.54e-03 GO:0005911 cell-cell junction
1.61 2.71e-03 GO:0016323 basolateral plasma membrane
1.06 3.00e-03 GO:0043226 organelle
1.91 4.46e-03 GO:0005924 cell-substrate adherens junction
1.06 4.74e-03 GO:0043229 intracellular organelle
1.88 5.36e-03 GO:0030055 cell-substrate junction
1.93 5.39e-03 GO:0030017 sarcomere
1.50 1.07e-02 GO:0015629 actin cytoskeleton
1.28 1.32e-02 GO:0042995 cell projection
1.07 1.87e-02 GO:0005737 cytoplasm
1.92 2.07e-02 GO:0043296 apical junction complex
1.20 2.14e-02 GO:0005856 cytoskeleton
1.09 3.16e-02 GO:0044422 organelle part
1.81 4.50e-02 GO:0005925 focal adhesion
1.21 4.60e-02 GO:0005654 nucleoplasm
1.86 4.80e-02 GO:0016327 apicolateral plasma membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.16 2.41e-16 GO:0005515 protein binding
1.06 5.92e-07 GO:0005488 binding
1.36 1.62e-05 GO:0001071 nucleic acid binding transcription factor activity
1.36 1.62e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.39 9.74e-05 GO:0019899 enzyme binding
1.42 9.52e-04 GO:0008092 cytoskeletal protein binding
1.37 1.41e-03 GO:0043565 sequence-specific DNA binding
1.54 2.17e-03 GO:0016563 transcription activator activity
1.29 2.43e-03 GO:0030528 transcription regulator activity
2.41 1.05e-02 GO:0008013 beta-catenin binding
1.61 1.56e-02 GO:0000975 regulatory region DNA binding
1.61 1.56e-02 GO:0001067 regulatory region nucleic acid binding
1.61 1.56e-02 GO:0044212 transcription regulatory region DNA binding
1.48 1.76e-02 GO:0003779 actin binding