Motif ID: SPZ1.p2

Z-value: 1.047


Transcription factors associated with SPZ1.p2:

Gene SymbolEntrez IDGene Name
SPZ1 84654 spermatogenic leucine zipper 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
SPZ1chr5_+_79651545-0.485.7e-02Click!


Activity profile for motif SPZ1.p2.

activity profile for motif SPZ1.p2


Sorted Z-values histogram for motif SPZ1.p2

Sorted Z-values for motif SPZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SPZ1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_29819647 1.318 NM_181718
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr4_-_22126437 1.206 NM_145290
GPR125
G protein-coupled receptor 125
chr2_-_220144254 1.151 OBSL1
obscurin-like 1
chr4_+_184257337 1.140 NM_024949
WWC2
WW and C2 domain containing 2
chrX_+_105856531 1.097 NM_194463
RNF128
ring finger protein 128
chr6_-_116488458 1.070 NM_002031
FRK
fyn-related kinase
chr17_+_72795567 1.030 NM_001113492
SEPT9
septin 9
chrX_-_128485121 1.029 SMARCA1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1
chr1_-_20684858 0.963 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr16_-_66535457 0.934 NM_000229
LCAT
lecithin-cholesterol acyltransferase
chr7_+_94374862 0.926 NM_001166160
NM_017650
PPP1R9A

protein phosphatase 1, regulatory (inhibitor) subunit 9A

chr20_-_22513050 0.905 NM_021784
FOXA2
forkhead box A2
chr7_+_45894480 0.874 NM_000596
IGFBP1
insulin-like growth factor binding protein 1
chr3_-_187025438 0.853 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr2_+_54536780 0.836 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr18_-_26935883 0.835 NM_004949
NM_024422
DSC2

desmocollin 2

chr10_+_123862430 0.808 TACC2
transforming, acidic coiled-coil containing protein 2
chr12_+_64504835 0.784 HMGA2
high mobility group AT-hook 2
chr3_-_187025501 0.780 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr6_-_128883125 0.773 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 53 entries
enrichment   p-value GO term description
2.06 8.97e-03 GO:0045216 cell-cell junction organization
2.01 3.82e-05 GO:0034330 cell junction organization
1.98 2.22e-02 GO:0030278 regulation of ossification
1.97 5.96e-04 GO:0034329 cell junction assembly
1.79 2.12e-02 GO:0001655 urogenital system development
1.62 2.69e-03 GO:0061061 muscle structure development
1.47 1.75e-03 GO:0000904 cell morphogenesis involved in differentiation
1.43 5.92e-04 GO:0032989 cellular component morphogenesis
1.43 4.09e-02 GO:0048812 neuron projection morphogenesis
1.42 8.85e-06 GO:0006351 transcription, DNA-dependent
1.41 5.35e-03 GO:0000902 cell morphogenesis
1.38 2.53e-04 GO:0048699 generation of neurons
1.37 5.39e-03 GO:0030182 neuron differentiation
1.37 7.57e-03 GO:0009790 embryo development
1.36 4.18e-02 GO:0030030 cell projection organization
1.35 1.94e-07 GO:0007399 nervous system development
1.35 8.10e-04 GO:0022008 neurogenesis
1.34 9.94e-04 GO:0032774 RNA biosynthetic process
1.33 1.40e-06 GO:0009653 anatomical structure morphogenesis
1.32 6.98e-03 GO:0048468 cell development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 25 entries
enrichment   p-value GO term description
2.00 3.86e-07 GO:0070161 anchoring junction
2.00 1.74e-04 GO:0044449 contractile fiber part
1.99 3.20e-06 GO:0005912 adherens junction
1.93 5.39e-03 GO:0030017 sarcomere
1.92 2.07e-02 GO:0043296 apical junction complex
1.91 1.17e-03 GO:0030016 myofibril
1.91 4.46e-03 GO:0005924 cell-substrate adherens junction
1.88 1.28e-03 GO:0043292 contractile fiber
1.88 5.36e-03 GO:0030055 cell-substrate junction
1.86 4.80e-02 GO:0016327 apicolateral plasma membrane
1.81 4.50e-02 GO:0005925 focal adhesion
1.68 1.54e-03 GO:0005911 cell-cell junction
1.61 2.71e-03 GO:0016323 basolateral plasma membrane
1.58 1.86e-09 GO:0030054 cell junction
1.50 1.07e-02 GO:0015629 actin cytoskeleton
1.28 1.32e-02 GO:0042995 cell projection
1.21 4.60e-02 GO:0005654 nucleoplasm
1.20 2.14e-02 GO:0005856 cytoskeleton
1.19 9.39e-04 GO:0044459 plasma membrane part
1.09 3.16e-02 GO:0044422 organelle part

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
enrichment   p-value GO term description
2.41 1.05e-02 GO:0008013 beta-catenin binding
1.61 1.56e-02 GO:0000975 regulatory region DNA binding
1.61 1.56e-02 GO:0001067 regulatory region nucleic acid binding
1.61 1.56e-02 GO:0044212 transcription regulatory region DNA binding
1.54 2.17e-03 GO:0016563 transcription activator activity
1.48 1.76e-02 GO:0003779 actin binding
1.42 9.52e-04 GO:0008092 cytoskeletal protein binding
1.39 9.74e-05 GO:0019899 enzyme binding
1.37 1.41e-03 GO:0043565 sequence-specific DNA binding
1.36 1.62e-05 GO:0001071 nucleic acid binding transcription factor activity
1.36 1.62e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.29 2.43e-03 GO:0030528 transcription regulator activity
1.16 2.41e-16 GO:0005515 protein binding
1.06 5.92e-07 GO:0005488 binding